Screening for Cognitive Impairment in Older Adults

Name: Work Video:
Duration: 3 min 30 s
Carrie D. Patnode; Leslie A Perdue; Rebecca C. Rossom; Megan C. Rushkin; Nadia Redmond; Rachel Thomas; Jennifer S Lin
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83, 103, 108, 113, 118, 124, 132, 137, 231, 264, 316, 365, 371], 'caregiver': [10, 135, 345, 394], 'health': [11], 'outcomes.': [12], '<h3>Objective</h3>': [13], 'To': [14], 'systematically': [15], 'review': [16, 141], 'the': [17, 41, 161, 202, 217, 277, 288, 321], 'test': [18], 'accuracy': [19, 203], 'screening': [22, 79, 165, 206, 295, 387], 'instruments': [23, 207, 374], 'benefits': [25, 362, 411], 'harms': [27], 'interventions': [29, 336, 403], 'to': [30, 39, 72, 95, 193, 208, 229, 238, 240, 283, 309, 326, 332, 354, 358], 'treat': [31, 310], 'in': [34, 179, 297, 340], 'older': [35, 150, 413], 'adults': [36, 414], '(≥65': [37], 'years)': [38], 'inform': [40], 'US': [42], 'Preventive': [43], 'Services': [44], 'Task': [45], 'Force.': [46], '<h3>Data': [47, 101], 'Sources</h3>': [48], 'MEDLINE,': [49], 'PubMed,': [50], 'PsycINFO,': [51], 'Cochrane': [53], 'Central': [54], 'Register': [55], 'Controlled': [57], 'Trials': [58], 'through': [59, 65], 'January': [60], '2019,': [61], 'with': [62, 89, 145, 220, 293, 303, 415], 'literature': [63], 'surveillance': [64], 'November': [66], '22,': [67], '2019.': [68], '<h3>Study': [69], 'Selection</h3>': [70], 'Fair-': [71], 'good-quality': [73], 'English-language': [74], 'studies': [75, 144, 196, 267], 'instruments,': [80], 'pharmacologic': [82], 'nonpharmacologic': [84], 'treatments': [85], 'aimed': [86], 'at': [87, 184], 'persons': [88, 302], 'mild': [90, 94, 282], '(MCI),': [93], 'moderate': [96, 284], 'dementia,': [97], 'or': [98, 248, 250, 252, 274, 281, 393, 396, 406, 420], 'their': [99, 421], 'caregivers.': [100, 422], 'Extraction': [102], 'Synthesis</h3>': [104], 'Independent': [105], 'critical': [106], 'appraisal': [107], 'data': [109], 'abstraction;': [110], 'random-effects': [111], 'meta-analyses': [112], 'qualitative': [114], 'synthesis.': [115], '<h3>Main': [116], 'Outcomes': [117], 'Measures</h3>': [119], 'Sensitivity,': [120], 'specificity;': [121], 'patient,': [122], 'caregiver,': [123], 'clinician': [125], 'decision-making;': [126], 'function,': [128], 'quality': [129, 181], 'life,': [131], 'neuropsychiatric': [133], 'symptoms;': [134], 'burden': [136, 346], 'well-being.': [138], '<h3>Results</h3>': [139], 'The': [140, 212], 'included': [142], '287': [143], 'more': [146, 269], 'than': [147, 270], '280': [148], '000': [149, 272], 'adults.': [151], 'One': [152], 'randomized': [153], 'clinical': [154, 368], 'trial': [155], '(RCT)': [156], '(n': [157, 197], '=': [158, 198, 257], '4005)': [159], 'examined': [160], 'direct': [162], 'effect': [163], 'for': [166, 337, 344, 388, 404, 412], 'on': [169, 320], 'outcomes,': [171], 'including': [172, 268], 'potential': [173], 'harms,': [174], 'finding': [175], 'no': [176, 382], 'significant': [177], 'differences': [178], 'health-related': [180], 'life': [183], '12': [185, 258, 359], 'months': [186, 331], '(effect': [187], 'size,': [188], '0.009': [189], '[95%': [190, 351], 'CI,': [191, 227, 236, 352], '–0.063': [192], '0.080]).': [194], 'Fifty-nine': [195], '38': [199], '531)': [200], 'addressed': [201, 276], '49': [205], 'detect': [209, 241, 377], 'impairment.': [211, 306, 379], 'Mini-Mental': [213], 'State': [214], 'Examination': [215], 'was': [216], 'most-studied': [218], 'instrument,': [219], 'a': [221, 244, 294, 341], 'pooled': [222], 'sensitivity': [223], '0.89': [225, 234], '(95%': [226, 235], '0.85': [228, 237], '0.92)': [230], 'specificity': [232], '0.93)': [239], 'dementia': [242], 'using': [243], 'cutoff': [245], '23': [247], 'less': [249, 253], '24': [251], '(15': [254], 'studies,': [255], 'n': [256], '796).': [259], 'Two': [260], 'hundred': [261], 'twenty-four': [262], 'RCTs': [263], '3': [265, 330, 333, 357], 'observational': [266], '240': [271], 'patients': [273, 405], 'caregivers': [275, 338, 407], 'treatment': [278, 289], 'MCI': [280], 'dementia.': [285], 'None': [286], 'trials': [290], 'were': [291, 301, 363], 'linked': [292], 'program;': [296], 'all': [298], 'cases,': [299], 'participants': [300], 'known': [304], 'Medications': [307], 'approved': [308], 'Alzheimer': [311], 'disease': [312], '(donepezil,': [313], 'galantamine,': [314], 'rivastigmine,': [315], 'memantine)': [317], 'improved': [318], 'scores': [319], 'ADAS-Cog': [322], '11': [323], 'by': [324], '1': [325], '2.5': [327], 'points': [328], 'over': [329, 356], 'years.': [334], 'Psychoeducation': [335], 'resulted': [339], 'small': [342, 364], 'benefit': [343], '(standardized': [347], 'mean': [348], 'difference,': [349], '–0.24': [350], '–0.36': [353], '–0.13)': [355], 'months.': [360], 'Intervention': [361], 'uncertain': [367], 'importance.': [369], '<h3>Conclusions': [370], 'Relevance</h3>': [372], 'Screening': [373], 'can': [375], 'adequately': [376], 'There': [380], 'is': [381], 'empirical': [383], 'evidence,': [384], 'however,': [385], 'that': [386], 'improves': [391], 'outcomes': [395], 'causes': [397], 'harm.': [398], 'It': [399], 'remains': [400], 'unclear': [401], 'whether': [402], 'provide': [408], 'clinically': [409], 'important': [410], 'earlier': [416], 'detected': [417]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3008391208', 'counts_by_year': [{'year': 2024, 'cited_by_count': 39}, {'year': 2023, 'cited_by_count': 48}, {'year': 2022, 'cited_by_count': 54}, {'year': 2021, 'cited_by_count': 40}, {'year': 2020, 'cited_by_count': 20}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 2}], 'updated_date': '2024-12-28T20:15:24.359524', 'created_date': '2020-03-06'}
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