Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3007986422', 'doi': 'https://doi.org/10.1016/j.jinf.2020.02.013', 'title': 'Analysis of angiotensin-converting enzyme 2 (ACE2) from different species sheds some light on cross-species receptor usage of a novel coronavirus 2019-nCoV', 'display_name': 'Analysis of angiotensin-converting enzyme 2 (ACE2) from different species sheds some light on cross-species receptor usage of a novel coronavirus 2019-nCoV', 'publication_year': 2020, 'publication_date': '2020-02-21', 'ids': {'openalex': 'https://openalex.org/W3007986422', 'doi': 'https://doi.org/10.1016/j.jinf.2020.02.013', 'mag': '3007986422', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/32092392', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/7127620'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.jinf.2020.02.013', 'pdf_url': 'http://www.journalofinfection.com/article/S0163445320300906/pdf', 'source': {'id': 'https://openalex.org/S19579164', 'display_name': 'Journal of Infection', 'issn_l': '0163-4453', 'issn': ['0163-4453', '1532-2742'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'letter', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'http://www.journalofinfection.com/article/S0163445320300906/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100448435', 'display_name': 'Rui Li', 'orcid': 'https://orcid.org/0000-0002-1829-1227'}, 'institutions': [{'id': 'https://openalex.org/I4210096196', 'display_name': 'Henan Academy of Agricultural Sciences', 'ror': 'https://ror.org/00vdyrj80', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I4210096196']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Rui Li', 'raw_affiliation_strings': ['Key Laboratory of Animal Immunology of the Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Animal Immunology of the Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China', 'institution_ids': ['https://openalex.org/I4210096196']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112591045', 'display_name': 'Songlin Qiao', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210096196', 'display_name': 'Henan Academy of Agricultural Sciences', 'ror': 'https://ror.org/00vdyrj80', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I4210096196']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Songlin Qiao', 'raw_affiliation_strings': ['Key Laboratory of Animal Immunology of the Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Animal Immunology of the Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China', 'institution_ids': ['https://openalex.org/I4210096196']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5007641506', 'display_name': 'Gaiping Zhang', 'orcid': 'https://orcid.org/0000-0002-3834-9975'}, 'institutions': [{'id': 'https://openalex.org/I4210096196', 'display_name': 'Henan Academy of Agricultural Sciences', 'ror': 'https://ror.org/00vdyrj80', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I4210096196']}, {'id': 'https://openalex.org/I4750791', 'display_name': 'Henan Agricultural University', 'ror': 'https://ror.org/04eq83d71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I4750791']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Gaiping Zhang', 'raw_affiliation_strings': ['College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 45002, China', 'Key Laboratory of Animal Immunology of the Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Animal Immunology of the Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China', 'institution_ids': ['https://openalex.org/I4210096196']}, {'raw_affiliation_string': 'College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 45002, China', 'institution_ids': ['https://openalex.org/I4750791']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5007641506'], 'corresponding_institution_ids': ['https://openalex.org/I4210096196', 'https://openalex.org/I4750791'], 'apc_list': {'value': 4000, 'currency': 'USD', 'value_usd': 4000, 'provenance': 'doaj'}, 'apc_paid': {'value': 4000, 'currency': 'USD', 'value_usd': 4000, 'provenance': 'doaj'}, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 129, 'citation_normalized_percentile': {'value': 0.999264, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '80', 'issue': '4', 'first_page': '469', 'last_page': '496'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10118', 'display_name': 'SARS-CoV-2 and COVID-19 Research', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10118', 'display_name': 'SARS-CoV-2 and COVID-19 Research', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10041', 'display_name': 'COVID-19 Clinical Research Studies', 'score': 0.9961, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10211', 'display_name': 'Computational Drug Discovery Methods', 'score': 0.9822, 'subfield': {'id': 'https://openalex.org/subfields/1703', 'display_name': 'Computational Theory and Mathematics'}, 'field': {'id': 'https://openalex.org/fields/17', 'display_name': 'Computer Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/coronavirus', 'display_name': 'Coronavirus', 'score': 0.65820706}, {'id': 'https://openalex.org/keywords/2019-20-coronavirus-outbreak', 'display_name': '2019-20 coronavirus outbreak', 'score': 0.5948393}, {'id': 'https://openalex.org/keywords/angiotensin-converting-enzyme-2', 'display_name': 'Angiotensin-converting enzyme 2', 'score': 0.57114536}, {'id': 'https://openalex.org/keywords/global-health', 'display_name': 'Global Health', 'score': 0.44979712}], 'concepts': [{'id': 'https://openalex.org/C3008058167', 'wikidata': 'https://www.wikidata.org/wiki/Q84263196', 'display_name': 'Coronavirus disease 2019 (COVID-19)', 'level': 4, 'score': 0.78431726}, {'id': 'https://openalex.org/C3007834351', 'wikidata': 'https://www.wikidata.org/wiki/Q82069695', 'display_name': 'Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)', 'level': 5, 'score': 0.693841}, {'id': 'https://openalex.org/C2777648638', 'wikidata': 'https://www.wikidata.org/wiki/Q57751738', 'display_name': 'Coronavirus', 'level': 5, 'score': 0.65820706}, {'id': 'https://openalex.org/C191935318', 'wikidata': 'https://www.wikidata.org/wiki/Q148', 'display_name': 'China', 'level': 2, 'score': 0.6090785}, {'id': 'https://openalex.org/C3006700255', 'wikidata': 'https://www.wikidata.org/wiki/Q81068910', 'display_name': '2019-20 coronavirus outbreak', 'level': 3, 'score': 0.5948393}, {'id': 'https://openalex.org/C2775946041', 'wikidata': 'https://www.wikidata.org/wiki/Q14875321', 'display_name': 'Angiotensin-converting enzyme 2', 'level': 5, 'score': 0.57114536}, {'id': 'https://openalex.org/C2777914695', 'wikidata': 'https://www.wikidata.org/wiki/Q12192', 'display_name': 'Pneumonia', 'level': 2, 'score': 0.54356635}, {'id': 'https://openalex.org/C138816342', 'wikidata': 'https://www.wikidata.org/wiki/Q189603', 'display_name': 'Public health', 'level': 2, 'score': 0.5389446}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.46348813}, {'id': 'https://openalex.org/C46578552', 'wikidata': 'https://www.wikidata.org/wiki/Q2725393', 'display_name': 'Global health', 'level': 3, 'score': 0.44979712}, {'id': 'https://openalex.org/C205649164', 'wikidata': 'https://www.wikidata.org/wiki/Q1071', 'display_name': 'Geography', 'level': 0, 'score': 0.4246471}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.38930663}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.31941697}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.15117776}, {'id': 'https://openalex.org/C524204448', 'wikidata': 'https://www.wikidata.org/wiki/Q788926', 'display_name': 'Infectious disease (medical specialty)', 'level': 3, 'score': 0.11683956}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.11426678}, {'id': 'https://openalex.org/C116675565', 'wikidata': 'https://www.wikidata.org/wiki/Q3241045', 'display_name': 'Outbreak', 'level': 2, 'score': 0.106698066}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.070154965}, {'id': 'https://openalex.org/C166957645', 'wikidata': 'https://www.wikidata.org/wiki/Q23498', 'display_name': 'Archaeology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D007703', 'descriptor_name': 'Peptidyl-Dipeptidase A', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D011991', 'descriptor_name': 'Receptors, Virus', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000085962', 'descriptor_name': 'Angiotensin-Converting Enzyme 2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000073640', 'descriptor_name': 'Betacoronavirus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000086382', 'descriptor_name': 'COVID-19', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018352', 'descriptor_name': 'Coronavirus Infections', 'qualifier_ui': 'Q000635', 'qualifier_name': 'transmission', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008958', 'descriptor_name': 'Models, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D058873', 'descriptor_name': 'Pandemics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011024', 'descriptor_name': 'Pneumonia, Viral', 'qualifier_ui': 'Q000635', 'qualifier_name': 'transmission', 'is_major_topic': False}, {'descriptor_ui': 'D011487', 'descriptor_name': 'Protein Conformation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000085064', 'descriptor_name': 'Receptors, Coronavirus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000086402', 'descriptor_name': 'SARS-CoV-2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016415', 'descriptor_name': 'Sequence Alignment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013045', 'descriptor_name': 'Species Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.jinf.2020.02.013', 'pdf_url': 'http://www.journalofinfection.com/article/S0163445320300906/pdf', 'source': {'id': 'https://openalex.org/S19579164', 'display_name': 'Journal of Infection', 'issn_l': '0163-4453', 'issn': ['0163-4453', '1532-2742'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc7127620', 'pdf_url': 'https://europepmc.org/articles/pmc7127620?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127620', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/32092392', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.jinf.2020.02.013', 'pdf_url': 'http://www.journalofinfection.com/article/S0163445320300906/pdf', 'source': {'id': 'https://openalex.org/S19579164', 'display_name': 'Journal of Infection', 'issn_l': '0163-4453', 'issn': ['0163-4453', '1532-2742'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.87, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 11, 'referenced_works': ['https://openalex.org/W1966238900', 'https://openalex.org/W1982533785', 'https://openalex.org/W2121757696', 'https://openalex.org/W2513547424', 'https://openalex.org/W2528687767', 'https://openalex.org/W3001836891', 'https://openalex.org/W3003217347', 'https://openalex.org/W3003668884', 'https://openalex.org/W3004280078', 'https://openalex.org/W3004348779', 'https://openalex.org/W3008394341'], 'related_works': ['https://openalex.org/W4289979282', 'https://openalex.org/W4211233539', 'https://openalex.org/W4211164148', 'https://openalex.org/W3217468344', 'https://openalex.org/W3197676681', 'https://openalex.org/W3113640840', 'https://openalex.org/W3015753260', 'https://openalex.org/W2389269289', 'https://openalex.org/W2379929390', 'https://openalex.org/W2082133861'], 'abstract_inverted_index': {'A': [0, 187], 'novel': [1, 76, 150, 356, 1194], 'coronavirus': [2, 42, 151, 208, 285, 320, 357, 429, 618, 855], 'from': [3, 243, 358, 459, 481, 668, 894, 1137], 'Wuhan': [4], 'in': [5, 17, 48, 72, 105, 124, 256, 310, 569, 588, 642, 649, 660, 810, 828, 889, 909, 942, 947, 956, 973, 995, 1048, 1081, 1086, 1167, 1179, 1246], 'central': [6], 'China,': [7, 74], 'named': [8], '2019-nCoV,': [9], 'has': [10, 94, 194, 822], 'recently': [11], 'caused': [12], 'an': [13, 360, 768, 816, 1154], 'epidemic': [14], 'of': [15, 75, 112, 116, 128, 155, 170, 185, 286, 308, 329, 367, 428, 452, 457, 479, 551, 616, 707, 772, 784, 794, 801, 841, 877, 1057, 1132, 1148, 1161, 1192, 1201, 1215, 1228], 'pneumonia': [16, 279], 'humans': [18, 846], 'and': [19, 102, 332, 387, 405, 426, 494, 500, 510, 517, 521, 525, 561, 581, 604, 645, 653, 663, 674, 688, 711, 733, 749, 758, 834, 847, 898, 932, 945, 971, 998, 1017, 1066, 1074, 1112, 1129, 1163, 1175, 1213, 1231, 1251], 'posed': [20], 'a': [21, 125, 138, 162, 226, 283, 311, 450, 537, 639, 679, 780, 785, 811, 1004, 1157], 'huge': [22], 'threat': [23], 'to': [24, 96, 108, 143, 147, 180, 314, 390, 585, 686, 774, 778, 825, 832, 880, 963, 984, 1119, 1187, 1256], 'global': [25], 'public': [26], 'health.1Wu': [27], 'F.': [28, 352, 423, 608, 838], 'Zhao': [29], 'S.': [30], 'Yu': [31], 'B.': [32, 272], 'Chen': [33], 'Y.-.M.': [34], 'Wang': [35, 62, 269], 'W.': [36, 210, 276, 610], 'Song': [37], 'Z.-.G.': [38], 'et': [39, 68, 192, 221, 277, 918, 1110], 'al.A': [40, 278], 'new': [41, 284], 'associated': [43, 281], 'with': [44, 282, 558, 591, 623, 911, 926, 981, 1053, 1181], 'human': [45, 305, 652, 890, 965, 1028, 1174], 'respiratory': [46, 206, 853], 'disease': [47], 'China.Nature.': [49], '2020;': [50, 82, 290, 370], '(PubMed': [51, 83, 235, 291, 412, 436, 627, 860], 'PMID:32015508)https://doi.org/10.1038/s41586-020-2008-3Crossref': [52], 'Scopus': [53, 85, 239, 293, 375, 419, 443, 632, 867], '(7481)': [54], 'Google': [55, 87, 241, 295, 377, 421, 445, 634, 869], 'Scholar,2Li': [56], 'Q.': [57], 'Guan': [58], 'X.': [59, 63], 'Wu': [60], 'P.': [61, 266], 'Zhou': [64], 'L.': [65, 274], 'Tong': [66], 'Y.': [67, 344], 'al.Early': [69], 'transmission': [70, 1160], 'dynamics': [71], 'Wuhan,': [73], 'coronavirus-infected': [77], 'pneumonia.N': [78], 'Engl': [79], 'J': [80], 'Med.': [81], 'PMID:31995857)https://doi.org/10.1056/NEJMoa2001316Crossref': [84], '(10590)': [86], 'Scholar': [88, 242, 296, 378, 446, 635, 870], 'To': [89], 'the': [90, 113, 133, 153, 168, 182, 201, 230, 259, 319, 380, 383, 460, 570, 575, 589, 596, 657, 661, 705, 718, 743, 770, 790, 798, 802, 875, 883, 892, 912, 948, 957, 964, 991, 1012, 1044, 1054, 1058, 1062, 1070, 1087, 1121, 1219, 1232, 1254, 1258], 'date': [91], '06/02/2020,': [92], '2019-nCoV': [93, 254, 309, 458, 550, 673, 687, 905, 982, 1104, 1162, 1182], 'led': [95], 'more': [97], 'than': [98], '31,000': [99], 'confirmed': [100], 'cases': [101], '637': [103], 'deaths': [104], 'China': [106, 117, 1229], 'according': [107], 'National': [109], 'Health': [110], 'Commission': [111], "People's": [114], 'Republic': [115], '(http://en.nhc.gov.cn/index.html).': [118], 'Cases': [119], 'have': [120, 176, 301], 'also': [121], 'been': [122, 178, 823], 'documented': [123], 'growing': [126], 'number': [127], 'other': [129, 298, 878, 1168, 1176], 'international': [130], 'locations,': [131], 'including': [132, 339, 484], 'United': [134], 'States': [135], '(https://www.cdc.gov/coronavirus/2019-ncov/index.html).': [136], 'As': [137, 647, 678], 'consequence,': [139], 'it': [140], 'is': [141, 161, 225, 448, 776, 908, 1020, 1084], 'urgent': [142], 'develop': [144], 'effective': [145], 'measures': [146], 'control': [148], 'this': [149, 171, 1193], 'on': [152, 318, 363, 454, 1035, 1089, 1144, 1156, 1173], 'basis': [154], 'its': [156, 676], 'pathogenesis.': [157], 'Host': [158], 'receptor': [159, 183, 202, 228, 333, 455, 461, 1146, 1190], 'recognition': [160, 354], 'determinant': [163], 'for': [164, 203, 229, 335, 693, 699, 717, 761, 850, 882, 904, 940, 1015, 1038, 1211, 1222, 1235, 1260], 'virus': [165], 'infection.': [166, 677], 'During': [167], 'time': [169], 'letter': [172], 'preparation,': [173], 'three': [174, 512], 'works': [175, 300], 'just': [177], 'published': [179], 'explore': [181], 'usage': [184, 307, 334, 456, 1147, 1191], '2019-nCoV.': [186, 340, 1149], 'work': [188, 914, 1204, 1259], 'by': [189, 355, 529, 915, 1107, 1207], 'Zheng-Li': [190, 916, 1108], 'Shi': [191, 917, 1109], 'al.': [193, 919, 1111], 'shown': [195, 648, 824], 'that': [196, 382, 534, 549, 666, 1114], 'angiotensin-converting': [197, 1133], 'enzyme': [198, 223, 1134], '2': [199, 224, 1135], '(ACE2),': [200], 'severe': [204, 851], 'acute': [205, 852], 'syndrome': [207, 854], '(SARS-CoV),3Li': [209], 'Moore': [211], 'M.J.': [212], 'Vasilieva': [213], 'N.': [214], 'Sui': [215], 'J.': [216, 346], 'Wong': [217], 'S.K.': [218], 'Berne': [219], 'M.A.': [220], 'al.Angiotensin-converting': [222], 'functional': [227], 'SARS': [231], 'coronavirus.Nature.': [232], '2003;': [233], '426': [234], 'PMID:14647384):': [236], '450-454Crossref': [237], 'PubMed': [238, 372, 418, 442, 631, 866], '(4499)': [240], 'human,': [244, 485], 'Rhinolophus': [245], 'sinicus': [246], 'bat,': [247], 'civet,': [248], 'swine': [249], 'but': [250], 'not': [251, 263, 465, 544, 556, 567, 977, 1002, 1102, 1117], 'mouse': [252, 958, 974, 997, 1016, 1049, 1099], 'mediate': [253, 675, 1103], 'infection': [255, 1105], 'vitro,': [257], 'while': [258, 723], 'detailed': [260], 'mechanisms': [261], 'are': [262, 583, 606, 714, 726, 735, 751, 1116], 'yet': [264], 'determined.4Zhou': [265], 'Yang': [267], 'X.-.L.': [268], 'X.-.G.': [270], 'Hu': [271], 'Zhang': [273, 275], 'outbreak': [280], 'probable': [287, 552], 'bat': [288, 553], 'origin.Nature.': [289], 'PMID:32015507)https://doi.org/10.1038/s41586-020-2012-7Crossref': [292], '(14262)': [294], 'The': [297, 527, 546, 969, 1077, 1196, 1241], 'two': [299, 496, 522], 'reported': [302, 1106], 'or': [303, 696, 928, 987, 1253], 'predicted': [304], 'ACE2': [306, 480, 560, 667, 766, 830, 961, 975, 1000, 1019, 1029, 1050, 1083, 1100, 1178], 'similar': [312, 1085], 'way': [313], 'SARS-CoV': [315, 592, 833], 'mainly': [316], 'based': [317, 362], 'spike': [321, 403, 430, 619, 1183], '(S)': [322], 'glycoproteins.5Letko': [323], 'M,': [324], 'Munster': [325], 'V.': [326], 'Functional': [327], 'assessment': [328], 'cell': [330], 'entry': [331], 'lineage': [336], 'b': [337], 'β-coronaviruses,': [338], 'bioRxiv.': [341], '2020:2020.01.22.915660.Google': [342], 'Scholar,6Wan': [343], 'Shang': [345], 'Graham': [347], 'R.': [348], 'Baric': [349], 'R.S.': [350], 'Li': [351, 609], 'Receptor': [353], 'Wuhan:': [359], 'analysis': [361, 840], 'decade-long': [364], 'structural': [365, 1013, 1130], 'studies': [366, 1172], 'SARS.J': [368], 'Virol.': [369, 433, 857], '(JVI.00127-20.': [371], 'PMID:31996437.': [373], 'eng)Crossref': [374], '(3133)': [376], 'Considering': [379], 'fact': [381], 'S': [384, 593], 'proteins': [385], 'mutate': [386], 'gain': [388], 'capability': [389], 'recognize': [391, 672], 'host': [392], 'receptors': [393], 'among': [394], 'species,7Hulswit': [395], 'R.J.G.': [396], 'de': [397], 'Haan': [398], 'C.A.M.': [399], 'Bosch': [400], 'B.J.': [401], 'Coronavirus': [402], 'protein': [404, 1184], 'tropism': [406], 'changes.Adv': [407], 'Virus': [408], 'Res.': [409], '2016;': [410, 434], '96': [411], 'PMID:27712627.': [413], 'Epub': [414, 438, 862], '2016/09/13.': [415], 'eng):': [416, 440, 629, 864], '29-57Crossref': [417], '(305)': [420], 'Scholar,8Li': [422], 'Structure,': [424], 'function,': [425], 'evolution': [427], 'proteins.Annu': [431], 'Rev': [432], '3': [435], 'PMID:27578435.': [437], '2016/08/25.': [439], '237-261Crossref': [441], '(1788)': [444], 'there': [447], 'still': [449], 'lack': [451], 'analyses': [453, 1095, 1131, 1152], 'perspective,': [462], 'which': [463, 565, 737, 907, 1140], 'does': [464, 1001, 1101], 'evolve': [466], 'as': [467, 469, 690, 767, 939, 1008, 1033], 'quickly': [468], 'viruses.': [470], 'Here,': [471], 'we': [472, 637, 872, 1022, 1126], 'firstly': [473], 'performed': [474], 'amino': [475], 'acid': [476], 'sequence': [477, 539, 1128], 'alignment': [478, 528], 'different': [482, 1138], 'species,': [483, 1139], 'five': [486], 'non-human': [487, 654, 669, 681], 'primates': [488, 655, 670, 682], '(gibbon,': [489], 'green': [490], 'monkey,': [491], 'macaque,': [492], 'orangutan': [493], 'chimpanzee),': [495], 'companion': [497], 'animals': [498, 504, 514, 713, 900, 934], '(cat': [499], 'dog),': [501], 'six': [502], 'domestic': [503, 710, 897, 931], '(bovine,': [505], 'sheep,': [506], 'goat,': [507], 'swine,': [508], 'horse': [509], 'chicken),': [511], 'wild': [513, 712, 899, 933], '(ferret,': [515], 'civet': [516, 765, 829], 'Chinese': [518], 'horseshoe': [519], 'bat)': [520], 'rodents': [523, 1115], '(mouse': [524], 'rat).': [526], 'Clustal': [530], 'W': [531], '2.1': [532], 'shows': [533], 'they': [535], 'share': [536, 656], 'high': [538], 'similarity': [540], 'except': [541], 'chicken': [542, 559], '(data': [543], 'shown).': [545], 'result': [547, 809], 'suggests': [548], 'origin': [554], 'may': [555, 671, 683, 796, 808, 901, 976, 1051], 'interact': [557], 'subsequently': [562], 'infect': [563], 'them,': [564], 'were': [566], 'considered': [568], 'following': [571], 'analyses.': [572, 1040], 'In': [573, 702, 788, 920, 950, 1041, 1124], 'ACE2,': [574, 891], 'regions': [576, 644, 662, 879], 'at': [577, 598, 745], 'position': [578], '30–41,': [579], '82–84': [580], '353–357': [582], 'demonstrated': [584], 'be': [586, 684, 826, 902, 936, 1120], 'involved': [587, 827], 'interaction': [590, 800, 1056, 1091], 'protein,': [594], 'where': [595], 'residues': [597, 706, 820, 888], 'positions': [599, 746], '31,': [600, 747], '35,': [601], '38,': [602], '82': [603, 750, 859], '353': [605], 'critical.9Li': [607], 'Farzan': [611], 'M.': [612], 'Harrison': [613], 'S.C.': [614], 'Structure': [615], 'sars': [617], 'receptor-binding': [620], 'domain': [621], 'complexed': [622], 'receptor.Science.': [624], '2005;': [625], '309': [626], 'PMID:16166518.': [628], '1864-1868Crossref': [630], '(1495)': [633], 'Therefore,': [636], 'took': [638], 'close': [640, 924], 'comparison': [641], 'these': [643, 806, 895, 1151], 'residues.': [646], 'Fig.': [650, 703, 1042], '1,': [651, 704], 'identity': [658], 'sequences': [659], 'residues,': [664], 'implying': [665], 'result,': [680], 'susceptible': [685, 1122], 'serve': [689], 'animal': [691, 1169], 'models': [692], 'antiviral': [694], 'research': [695], 'intermediate': [697], 'hosts': [698], 'cross-species': [700, 922, 1145, 1189], 'transmission.': [701], 'most': [708, 887], 'companion,': [709, 930], 'conserved,': [715, 736], 'especially': [716], 'critical': [719], 'ones': [720, 725, 893], 'stated': [721], 'above,': [722], 'certain': [724, 952], 'variable.': [727], 'For': [728], 'example,': [729, 769], 'Lys31,': [730], 'Glu35,': [731], 'Asp/Glu38': [732], 'Lys353': [734, 1009], 'probably': [738], 'form': [739, 779, 978, 1003], 'salt': [740, 786, 1006, 1071], 'bridges.': [741], 'Interestingly,': [742], 'changes': [744, 754, 807, 954, 1063], '38': [748], 'observed.': [752], 'These': [753, 1094], 'suggest': [755], 'steric': [756], 'hindrance': [757], 'electrostatic': [759, 986, 1075], 'interference': [760], 'host-virus': [762], 'interaction.': [763], 'Taking': [764], 'change': [771, 992, 1045, 1078], 'Lys31': [773], 'Thr31': [775], 'likely': [777, 1118], 'hydrogen': [781], 'bond': [782], 'instead': [783], 'bridge.': [787], 'addition,': [789], 'polar': [791], 'side': [792], 'chain': [793], 'Thr82': [795], 'influence': [797], 'hydrophobic': [799, 1055], 'original': [803, 1059], 'Met82.': [804, 1060], 'All': [805, 1150], 'lower': [812], 'binding': [813, 831], 'affinity.': [814], 'However,': [815], 'additional': [817], 'region': [818], 'covering': [819], '90–93': [821], 'enhance': [835], 'their': [836, 985], 'interaction.10Li': [837], 'Structural': [839, 1171], 'major': [842], 'species': [843, 1177], 'barriers': [844], 'between': [845], 'palm': [848], 'civets': [849], 'infections.J': [856], '2008;': [858], 'PMID:18448527.': [861], '2008/04/30.': [863], '6984-6991Crossref': [865], '(140)': [868], 'Consequently,': [871], "can't": [873], 'preclude': [874], 'existence': [876], 'compensate': [881], 'residue': [884], 'changes.': [885], 'With': [886], 'compaion,': [896], 'favorable': [903, 979], 'recognition,': [906], 'consistent': [910], 'recent': [913], 'case': [921], 'transmission,': [923], 'contact': [925], 'sick': [927], 'asymptomatic': [929], 'should': [935], 'cautious,': [937], 'such': [938], 'workers': [941], 'livestock': [943], 'farming': [944], 'travellers': [946], 'wild.': [949], 'contrast,': [951], 'significant': [953], 'occur': [955], 'and/or': [959], 'rat': [960, 999, 1018, 1082], 'compared': [962], 'one': [966], '(Fig.': [967, 1092], '1).': [968], 'Asn31': [970, 1065], 'Ser82': [972, 1047], 'interactions': [980], 'due': [983], 'hydrophilic': [988], 'characteristics.': [989], 'Importantly,': [990], 'into': [993, 1046, 1064, 1079], 'His353': [994, 1067, 1080], 'both': [996], 'strong': [1005], 'bridge': [1007, 1072], 'does.': [1010], 'Since': [1011], 'information': [1014], 'unavailable,': [1021], 'carried': [1023], 'out': [1024], 'homology': [1025], 'modeling': [1026], 'using': [1027], '(PDB': [1030], 'code': [1031], '2AJF)': [1032], 'template': [1034], 'online': [1036], '(https://swissmodel.expasy.org)': [1037], 'further': [1039, 1165], '2A,': [1043], 'interfere': [1052], 'Additionally,': [1061], 'definitely': [1068], 'affect': [1069], 'formation': [1073], 'potential.': [1076], 'effect': [1088], 'receptor-virus': [1090], '2B).': [1093], 'partially': [1096], 'explain': [1097], 'why': [1098], 'assume': [1113], 'host.': [1123], 'conclusion,': [1125], 'conducted': [1127], '(ACE2)': [1136], 'sheds': [1141], 'some': [1142], 'light': [1143], 'raise': [1153], 'alert': [1155], 'potential': [1158], 'interspecies': [1159], 'propose': [1164], 'surveillance': [1166], 'populations.': [1170], 'complex': [1180], 'will': [1185], 'contribute': [1186], 'understanding': [1188], 'coronavirus.': [1195], 'authors': [1197], 'declare': [1198], 'no': [1199, 1244], 'conflict': [1200], 'interest.': [1202], 'This': [1203], 'was': [1205], 'supported': [1206], 'Henan': [1208, 1236], 'Emergency': [1209], 'Project': [1210], 'Prevention': [1212], 'Control': [1214], '2019': [1216], 'Novel': [1217], 'Coronavirus,': [1218], 'Earmarked': [1220], 'Fund': [1221, 1234], 'Modern': [1223], 'Agro-industry': [1224], 'Technology': [1225], 'Research': [1226, 1238], 'System': [1227, 1239], '(CARS-35)': [1230], 'Special': [1233], 'Agriculture': [1237], '(S2012-06).': [1240], 'funders': [1242], 'had': [1243], 'role': [1245], 'study': [1247], 'design,': [1248], 'data': [1249], 'collection': [1250], 'interpretation,': [1252], 'decision': [1255], 'submit': [1257], 'publication.': [1261]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3007986422', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 7}, {'year': 2022, 'cited_by_count': 14}, {'year': 2021, 'cited_by_count': 36}, {'year': 2020, 'cited_by_count': 69}], 'updated_date': '2024-12-20T05:00:16.007578', 'created_date': '2020-03-06'}