Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3007675747', 'doi': 'https://doi.org/10.1002/brb3.1529', 'title': 'Ionizing radiation modulates vascular endothelial growth factor expression through STAT3 signaling pathway in rat neonatal primary astrocyte cultures', 'display_name': 'Ionizing radiation modulates vascular endothelial growth factor expression through STAT3 signaling pathway in rat neonatal primary astrocyte cultures', 'publication_year': 2020, 'publication_date': '2020-02-27', 'ids': {'openalex': 'https://openalex.org/W3007675747', 'doi': 'https://doi.org/10.1002/brb3.1529', 'mag': '3007675747', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/32106359', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/7177558'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/brb3.1529', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/brb3.1529', 'source': {'id': 'https://openalex.org/S2764450051', 'display_name': 'Brain and Behavior', 'issn_l': '2162-3279', 'issn': ['2162-3279'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/brb3.1529', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5056611624', 'display_name': 'Guijuan Zhou', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210143187', 'display_name': 'First Affiliated Hospital of University of South China', 'ror': 'https://ror.org/049z3cb60', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210143187']}, {'id': 'https://openalex.org/I91935597', 'display_name': 'University of South China', 'ror': 'https://ror.org/03mqfn238', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I91935597']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Guijuan Zhou', 'raw_affiliation_strings': ['The First Afliated Hospital of University of South China, University of South China, Hengyang, China'], 'affiliations': [{'raw_affiliation_string': 'The First Afliated Hospital of University of South China, University of South China, Hengyang, China', 'institution_ids': ['https://openalex.org/I4210143187', 'https://openalex.org/I91935597']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027459729', 'display_name': 'Yan Xu', 'orcid': 'https://orcid.org/0000-0003-0379-8866'}, 'institutions': [{'id': 'https://openalex.org/I4210143187', 'display_name': 'First Affiliated Hospital of University of South China', 'ror': 'https://ror.org/049z3cb60', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210143187']}, {'id': 'https://openalex.org/I91935597', 'display_name': 'University of South China', 'ror': 'https://ror.org/03mqfn238', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I91935597']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yan Xu', 'raw_affiliation_strings': ['The First Afliated Hospital of University of South China, University of South China, Hengyang, China'], 'affiliations': [{'raw_affiliation_string': 'The First Afliated Hospital of University of South China, University of South China, Hengyang, China', 'institution_ids': ['https://openalex.org/I4210143187', 'https://openalex.org/I91935597']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044734672', 'display_name': 'Bing He', 'orcid': 'https://orcid.org/0000-0002-9694-6591'}, 'institutions': [{'id': 'https://openalex.org/I4210143187', 'display_name': 'First Affiliated Hospital of University of South China', 'ror': 'https://ror.org/049z3cb60', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210143187']}, {'id': 'https://openalex.org/I91935597', 'display_name': 'University of South China', 'ror': 'https://ror.org/03mqfn238', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I91935597']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Bing He', 'raw_affiliation_strings': ['The First Afliated Hospital of University of South China, University of South China, Hengyang, China'], 'affiliations': [{'raw_affiliation_string': 'The First Afliated Hospital of University of South China, University of South China, Hengyang, China', 'institution_ids': ['https://openalex.org/I4210143187', 'https://openalex.org/I91935597']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006897054', 'display_name': 'Rundong Ma', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210143187', 'display_name': 'First Affiliated Hospital of University of South China', 'ror': 'https://ror.org/049z3cb60', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210143187']}, {'id': 'https://openalex.org/I91935597', 'display_name': 'University of South China', 'ror': 'https://ror.org/03mqfn238', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I91935597']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Rundong Ma', 'raw_affiliation_strings': ['The First Afliated Hospital of University of South China, University of South China, Hengyang, China'], 'affiliations': [{'raw_affiliation_string': 'The First Afliated Hospital of University of South China, University of South China, Hengyang, China', 'institution_ids': ['https://openalex.org/I4210143187', 'https://openalex.org/I91935597']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100449855', 'display_name': 'Yilin Wang', 'orcid': 'https://orcid.org/0000-0002-8455-390X'}, 'institutions': [{'id': 'https://openalex.org/I4210143187', 'display_name': 'First Affiliated Hospital of University of South China', 'ror': 'https://ror.org/049z3cb60', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210143187']}, {'id': 'https://openalex.org/I91935597', 'display_name': 'University of South China', 'ror': 'https://ror.org/03mqfn238', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I91935597']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yilin Wang', 'raw_affiliation_strings': ['The First Afliated Hospital of University of South China, University of South China, Hengyang, China'], 'affiliations': [{'raw_affiliation_string': 'The First Afliated Hospital of University of South China, University of South China, Hengyang, China', 'institution_ids': ['https://openalex.org/I4210143187', 'https://openalex.org/I91935597']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5082449761', 'display_name': 'Yunqian Chang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210143187', 'display_name': 'First Affiliated Hospital of University of South China', 'ror': 'https://ror.org/049z3cb60', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210143187']}, {'id': 'https://openalex.org/I91935597', 'display_name': 'University of South China', 'ror': 'https://ror.org/03mqfn238', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I91935597']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yunqian Chang', 'raw_affiliation_strings': ['The First Afliated Hospital of University of South China, University of South China, Hengyang, China'], 'affiliations': [{'raw_affiliation_string': 'The First Afliated Hospital of University of South China, University of South China, Hengyang, China', 'institution_ids': ['https://openalex.org/I4210143187', 'https://openalex.org/I91935597']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050480498', 'display_name': 'Yangzhi Xie', 'orcid': 'https://orcid.org/0000-0003-2248-9719'}, 'institutions': [{'id': 'https://openalex.org/I4210143187', 'display_name': 'First Affiliated Hospital of University of South China', 'ror': 'https://ror.org/049z3cb60', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210143187']}, {'id': 'https://openalex.org/I91935597', 'display_name': 'University of South China', 'ror': 'https://ror.org/03mqfn238', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I91935597']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yangzhi Xie', 'raw_affiliation_strings': ["Leiyang People's Hospital, Leiyang, China", 'The First Afliated Hospital of University of South China, University of South China, Hengyang, China'], 'affiliations': [{'raw_affiliation_string': 'The First Afliated Hospital of University of South China, University of South China, Hengyang, China', 'institution_ids': ['https://openalex.org/I4210143187', 'https://openalex.org/I91935597']}, {'raw_affiliation_string': "Leiyang People's Hospital, Leiyang, China", 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023929740', 'display_name': 'Lin Wu', 'orcid': 'https://orcid.org/0000-0001-9642-223X'}, 'institutions': [{'id': 'https://openalex.org/I4210143187', 'display_name': 'First Affiliated Hospital of University of South China', 'ror': 'https://ror.org/049z3cb60', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210143187']}, {'id': 'https://openalex.org/I91935597', 'display_name': 'University of South China', 'ror': 'https://ror.org/03mqfn238', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I91935597']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Lin Wu', 'raw_affiliation_strings': ['The First Afliated Hospital of University of South China, University of South China, Hengyang, China'], 'affiliations': [{'raw_affiliation_string': 'The First Afliated Hospital of University of South China, University of South China, Hengyang, China', 'institution_ids': ['https://openalex.org/I4210143187', 'https://openalex.org/I91935597']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070744644', 'display_name': 'Jianghua Huang', 'orcid': 'https://orcid.org/0000-0003-0437-1303'}, 'institutions': [{'id': 'https://openalex.org/I4210143187', 'display_name': 'First Affiliated Hospital of University of South China', 'ror': 'https://ror.org/049z3cb60', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210143187']}, {'id': 'https://openalex.org/I91935597', 'display_name': 'University of South China', 'ror': 'https://ror.org/03mqfn238', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I91935597']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jianghua Huang', 'raw_affiliation_strings': ['The First Afliated Hospital of University of South China, University of South China, Hengyang, China'], 'affiliations': [{'raw_affiliation_string': 'The First Afliated Hospital of University of South China, University of South China, Hengyang, China', 'institution_ids': ['https://openalex.org/I4210143187', 'https://openalex.org/I91935597']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5028837344', 'display_name': 'Zijian Xiao', 'orcid': 'https://orcid.org/0000-0001-5137-9549'}, 'institutions': [{'id': 'https://openalex.org/I4210143187', 'display_name': 'First Affiliated Hospital of University of South China', 'ror': 'https://ror.org/049z3cb60', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210143187']}, {'id': 'https://openalex.org/I91935597', 'display_name': 'University of South China', 'ror': 'https://ror.org/03mqfn238', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I91935597']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Zijian Xiao', 'raw_affiliation_strings': ['The First Afliated Hospital of University of South China, University of South China, Hengyang, China'], 'affiliations': [{'raw_affiliation_string': 'The First Afliated Hospital of University of South China, University of South China, Hengyang, China', 'institution_ids': ['https://openalex.org/I4210143187', 'https://openalex.org/I91935597']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5028837344'], 'corresponding_institution_ids': ['https://openalex.org/I4210143187', 'https://openalex.org/I91935597'], 'apc_list': {'value': 2200, 'currency': 'EUR', 'value_usd': 2900, 'provenance': 'doaj'}, 'apc_paid': {'value': 2200, 'currency': 'EUR', 'value_usd': 2900, 'provenance': 'doaj'}, 'fwci': 1.095, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 13, 'citation_normalized_percentile': {'value': 0.812377, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 89, 'max': 90}, 'biblio': {'volume': '10', 'issue': '4', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11503', 'display_name': 'Role of STAT3 in Cancer Inflammation and Immunity', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11503', 'display_name': 'Role of STAT3 in Cancer Inflammation and Immunity', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T14245', 'display_name': 'Role of Pentraxins in Innate Immunity and Inflammation', 'score': 0.9905, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12626', 'display_name': 'Impact of Chronic Stress on Cancer Progression', 'score': 0.9875, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/inflammation', 'display_name': 'Inflammation', 'score': 0.501815}], 'concepts': [{'id': 'https://openalex.org/C2778923194', 'wikidata': 'https://www.wikidata.org/wiki/Q14912019', 'display_name': 'STAT3', 'level': 3, 'score': 0.74327755}, {'id': 'https://openalex.org/C2777025900', 'wikidata': 'https://www.wikidata.org/wiki/Q29725', 'display_name': 'Vascular endothelial growth factor', 'level': 3, 'score': 0.64246535}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.5866024}, {'id': 'https://openalex.org/C2777542381', 'wikidata': 'https://www.wikidata.org/wiki/Q502961', 'display_name': 'Astrocyte', 'level': 3, 'score': 0.5600872}, {'id': 'https://openalex.org/C171958077', 'wikidata': 'https://www.wikidata.org/wiki/Q419333', 'display_name': 'STAT protein', 'level': 4, 'score': 0.5409149}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.52081025}, {'id': 'https://openalex.org/C2780495277', 'wikidata': 'https://www.wikidata.org/wiki/Q905442', 'display_name': 'Glial fibrillary acidic protein', 'level': 3, 'score': 0.49733785}, {'id': 'https://openalex.org/C57074206', 'wikidata': 'https://www.wikidata.org/wiki/Q14197552', 'display_name': 'MAPK/ERK pathway', 'level': 3, 'score': 0.45445916}, {'id': 'https://openalex.org/C2775960820', 'wikidata': 'https://www.wikidata.org/wiki/Q408378', 'display_name': 'Growth factor', 'level': 3, 'score': 0.41909227}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.41029382}, {'id': 'https://openalex.org/C146285616', 'wikidata': 'https://www.wikidata.org/wiki/Q7916455', 'display_name': 'Vascular endothelial growth factor A', 'level': 4, 'score': 0.41013944}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.40945137}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.40915832}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.40816343}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.33382446}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.31835377}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.28042948}, {'id': 'https://openalex.org/C529278444', 'wikidata': 'https://www.wikidata.org/wiki/Q47273', 'display_name': 'Central nervous system', 'level': 2, 'score': 0.16651425}, {'id': 'https://openalex.org/C204232928', 'wikidata': 'https://www.wikidata.org/wiki/Q899285', 'display_name': 'Immunohistochemistry', 'level': 2, 'score': 0.13376433}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.085025996}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.08193982}, {'id': 'https://openalex.org/C167734588', 'wikidata': 'https://www.wikidata.org/wiki/Q4356503', 'display_name': 'VEGF receptors', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001253', 'descriptor_name': 'Astrocytes', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': True}, {'descriptor_ui': 'D011839', 'descriptor_name': 'Radiation, Ionizing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D050796', 'descriptor_name': 'STAT3 Transcription Factor', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': True}, {'descriptor_ui': 'D042461', 'descriptor_name': 'Vascular Endothelial Growth Factor A', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001253', 'descriptor_name': 'Astrocytes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001253', 'descriptor_name': 'Astrocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002540', 'descriptor_name': 'Cerebral Cortex', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D002540', 'descriptor_name': 'Cerebral Cortex', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002540', 'descriptor_name': 'Cerebral Cortex', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005904', 'descriptor_name': 'Glial Fibrillary Acidic Protein', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005904', 'descriptor_name': 'Glial Fibrillary Acidic Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017207', 'descriptor_name': 'Rats, Sprague-Dawley', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050796', 'descriptor_name': 'STAT3 Transcription Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D042461', 'descriptor_name': 'Vascular Endothelial Growth Factor A', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/brb3.1529', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/brb3.1529', 'source': {'id': 'https://openalex.org/S2764450051', 'display_name': 'Brain and Behavior', 'issn_l': '2162-3279', 'issn': ['2162-3279'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/0c539b7b2cc1474a9f9af43a3dfb8182', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc7177558', 'pdf_url': 'https://europepmc.org/articles/pmc7177558?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177558', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/32106359', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/brb3.1529', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/brb3.1529', 'source': {'id': 'https://openalex.org/S2764450051', 'display_name': 'Brain and Behavior', 'issn_l': '2162-3279', 'issn': ['2162-3279'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.8}], 'grants': [{'funder': 'https://openalex.org/F4320322843', 'funder_display_name': 'Natural Science Foundation of\xa0Hunan Province', 'award_id': '2017JJ3273'}], 'datasets': [], 'versions': [], 'referenced_works_count': 31, 'referenced_works': ['https://openalex.org/W1524986137', 'https://openalex.org/W1536119616', 'https://openalex.org/W1975828751', 'https://openalex.org/W1976406616', 'https://openalex.org/W1989838140', 'https://openalex.org/W1996489820', 'https://openalex.org/W2007897471', 'https://openalex.org/W2019615335', 'https://openalex.org/W2029739938', 'https://openalex.org/W2047752735', 'https://openalex.org/W2049640107', 'https://openalex.org/W2057016599', 'https://openalex.org/W2079208301', 'https://openalex.org/W2084926770', 'https://openalex.org/W2093673524', 'https://openalex.org/W2093979417', 'https://openalex.org/W2146269545', 'https://openalex.org/W2165477627', 'https://openalex.org/W2170810978', 'https://openalex.org/W2173225193', 'https://openalex.org/W2174482320', 'https://openalex.org/W2235105384', 'https://openalex.org/W2400419369', 'https://openalex.org/W2530157423', 'https://openalex.org/W2566300341', 'https://openalex.org/W2592716952', 'https://openalex.org/W2610627565', 'https://openalex.org/W2773139792', 'https://openalex.org/W2794697922', 'https://openalex.org/W2925613754', 'https://openalex.org/W2930150135'], 'related_works': ['https://openalex.org/W2891863700', 'https://openalex.org/W2390458645', 'https://openalex.org/W2383141715', 'https://openalex.org/W2349220395', 'https://openalex.org/W2148585034', 'https://openalex.org/W2076206894', 'https://openalex.org/W2058391066', 'https://openalex.org/W2021735051', 'https://openalex.org/W2011704181', 'https://openalex.org/W1964650815'], 'abstract_inverted_index': {'Abstract': [0], 'Background': [1], 'and': [2, 22, 47, 52, 63, 77, 94, 106, 129, 179, 193, 227, 255, 276], 'Purpose': [3], 'Radiation‐induced': [4], 'brain': [5, 290], 'injury': [6], '(RBI)': [7], 'usually': [8], 'occurs': [9], 'six': [10], 'months': [11], 'to': [12, 139, 210], 'three': [13], 'years': [14], 'after': [15, 117, 159, 236], 'irradiation,': [16], 'often': [17], 'shows': [18], 'cognitive': [19], 'dysfunction,': [20], 'epilepsy,': [21], 'other': [23], 'neurological': [24], 'dysfunction.': [25], 'In': [26, 87], 'severe': [27], 'cases,': [28], 'it': [29, 53], 'can': [30, 173], 'cause': [31], 'a': [32, 55, 252], 'wide': [33], 'range': [34], 'of': [35, 45, 50, 75, 83, 108, 121, 143, 157, 164, 169, 183, 196, 215, 220, 230, 233, 249, 274, 288], 'cerebral': [36], 'edema,': [37], 'even': [38], 'herniation.': [39], 'It': [40], 'seriously': [41], 'threatens': [42], 'the': [43, 60, 65, 73, 92, 102, 136, 141, 155, 162, 181, 184, 194, 203, 213, 221, 228, 247, 263, 272, 286], 'survival': [44], 'patients': [46], 'their': [48], 'quality': [49], 'life,': [51], 'becomes': [54], 'key': [56], 'factor': [57, 147, 200], 'in': [58, 68, 97, 149, 154, 202, 251, 285], 'limiting': [59], 'radiation': [61, 223], 'dose': [62], 'lowering': [64], 'therapeutic': [66, 80], 'efficacy': [67], 'recent': [69], 'years.': [70], 'Therefore,': [71], 'studying': [72], 'pathogenesis': [74, 287], 'RBI': [76], 'exploring': [78], 'new': [79], 'targets': [81], 'are': [82], 'great': [84], 'significance.': [85], 'Methods': [86], 'our': [88], 'study,': [89], 'we': [90, 134, 266], 'observed': [91], 'activation': [93, 115, 156, 185, 224, 248, 273], 'secretory': [95], 'function': [96], 'astrocytes': [98, 158, 250, 275], 'as': [99, 101], 'well': [100], 'intracellular': [103], 'signal': [104, 112, 150], 'transducer': [105], 'activator': [107], 'transcription': [109], '3': [110], '(STAT3)': [111], 'transduction': [113, 151], 'pathway': [114, 217, 282], 'status': [116], 'exposing': [118], 'different': [119], 'doses': [120], 'X‐ray': [122, 243, 256, 269], 'irradiation': [123, 244, 257, 270], 'by': [124], 'using': [125], 'MTT,': [126], 'Immunocytologic': [127], 'analysis,': [128], 'Western': [130], 'blot': [131], 'analysis.': [132], 'Further,': [133], 'used': [135], 'same': [137, 264], 'way': [138], 'explore': [140], 'role': [142], 'vascular': [144, 197], 'endothelial': [145, 166, 198], 'growth': [146, 167, 199], '(VEGF)': [148, 201], 'pathways': [152], 'playing': [153], 'irradiating': [160], 'through': [161], 'use': [163], 'specificInhivascular': [165], 'factorbitors': [168], 'STAT3.': [170], 'Results': [171], 'Ast': [172, 222], 'be': [174], 'directly': [175, 245], 'activated,': [176], 'reactive': [177], 'hyperplasia': [178], 'hypertrophy,': [180], 'expression': [182, 195, 229, 232], 'marker': [186], 'glial': [187], 'fibrillary': [188], 'acidic': [189], 'protein': [190], 'is': [191, 205], 'increased,': [192, 206], 'cells': [204], 'which': [207], 'may': [208, 283], 'lead': [209], 'RBI.': [211], 'After': [212], 'addition': [214], 'STAT3': [216, 259, 280], 'inhibitor,': [218], 'most': [219], 'was': [225], 'suppressed,': [226], 'high‐level': [231], 'VEGF': [234], 'decreased': [235], 'irradiation.': [237], 'Conclusion': [238], 'Our': [239], 'findings': [240], 'demonstrated': [241], 'that': [242, 268], 'induced': [246, 271], 'persistent': [253], 'manner': [254], 'activated': [258], 'signaling': [260, 281], 'pathway.': [261], 'As': [262], 'time,': [265], 'found': [267], 'secretion': [277], 'cytokine.': [278], 'The': [279], 'participate': [284], 'radiation‐induced': [289], 'injury.': [291]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3007675747', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 3}], 'updated_date': '2024-09-13T14:56:56.092714', 'created_date': '2020-03-06'}