Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3003302501', 'doi': 'https://doi.org/10.1186/s12859-019-3325-0', 'title': 'Reconstruction and analysis of a carbon-core metabolic network for Dunaliella salina', 'display_name': 'Reconstruction and analysis of a carbon-core metabolic network for Dunaliella salina', 'publication_year': 2020, 'publication_date': '2020-01-02', 'ids': {'openalex': 'https://openalex.org/W3003302501', 'doi': 'https://doi.org/10.1186/s12859-019-3325-0', 'mag': '3003302501', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/31898485', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6941287'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s12859-019-3325-0', 'pdf_url': 'https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-019-3325-0', 'source': {'id': 'https://openalex.org/S19032547', 'display_name': 'BMC Bioinformatics', 'issn_l': '1471-2105', 'issn': ['1471-2105'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-019-3325-0', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5022510144', 'display_name': 'Melanie Fachet', 'orcid': 'https://orcid.org/0000-0002-2530-4057'}, 'institutions': [{'id': 'https://openalex.org/I4210127568', 'display_name': 'Max Planck Institute for Dynamics of Complex Technical Systems', 'ror': 'https://ror.org/030h7k016', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I149899117', 'https://openalex.org/I4210127568']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Melanie Fachet', 'raw_affiliation_strings': ['Max Planck Institute for Dynamics of Complex Technical Systems, Process Systems Engineering, Sandtorstr. 1, Magdeburg, 39106, Germany'], 'affiliations': [{'raw_affiliation_string': 'Max Planck Institute for Dynamics of Complex Technical Systems, Process Systems Engineering, Sandtorstr. 1, Magdeburg, 39106, Germany', 'institution_ids': ['https://openalex.org/I4210127568']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053934743', 'display_name': 'Carina Witte', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210127568', 'display_name': 'Max Planck Institute for Dynamics of Complex Technical Systems', 'ror': 'https://ror.org/030h7k016', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I149899117', 'https://openalex.org/I4210127568']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Carina Witte', 'raw_affiliation_strings': ['Max Planck Institute for Dynamics of Complex Technical Systems, Process Systems Engineering, Sandtorstr. 1, Magdeburg, 39106, Germany'], 'affiliations': [{'raw_affiliation_string': 'Max Planck Institute for Dynamics of Complex Technical Systems, Process Systems Engineering, Sandtorstr. 1, Magdeburg, 39106, Germany', 'institution_ids': ['https://openalex.org/I4210127568']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020438172', 'display_name': 'Robert J. Flassig', 'orcid': 'https://orcid.org/0000-0002-7092-1046'}, 'institutions': [{'id': 'https://openalex.org/I4210146756', 'display_name': 'Brandenburg University of Applied Sciences', 'ror': 'https://ror.org/04qj3gf68', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I4210146756']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Robert J. Flassig', 'raw_affiliation_strings': ['Brandenburg University of Applied Sciences, Department of Engineering, Magdeburger Str. 50, Brandenburg an der Havel, 14770, Germany'], 'affiliations': [{'raw_affiliation_string': 'Brandenburg University of Applied Sciences, Department of Engineering, Magdeburger Str. 50, Brandenburg an der Havel, 14770, Germany', 'institution_ids': ['https://openalex.org/I4210146756']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030556444', 'display_name': 'Liisa Rihko‐Struckmann', 'orcid': 'https://orcid.org/0000-0003-0222-7236'}, 'institutions': [{'id': 'https://openalex.org/I4210127568', 'display_name': 'Max Planck Institute for Dynamics of Complex Technical Systems', 'ror': 'https://ror.org/030h7k016', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I149899117', 'https://openalex.org/I4210127568']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Liisa K. Rihko-Struckmann', 'raw_affiliation_strings': ['Max Planck Institute for Dynamics of Complex Technical Systems, Process Systems Engineering, Sandtorstr. 1, Magdeburg, 39106, Germany'], 'affiliations': [{'raw_affiliation_string': 'Max Planck Institute for Dynamics of Complex Technical Systems, Process Systems Engineering, Sandtorstr. 1, Magdeburg, 39106, Germany', 'institution_ids': ['https://openalex.org/I4210127568']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006263122', 'display_name': 'Zaid McKie‐Krisberg', 'orcid': 'https://orcid.org/0000-0002-8437-0011'}, 'institutions': [{'id': 'https://openalex.org/I83041322', 'display_name': 'Brooklyn College', 'ror': 'https://ror.org/019k4jq75', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I83041322']}, {'id': 'https://openalex.org/I174216632', 'display_name': 'City University of New York', 'ror': 'https://ror.org/00453a208', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I174216632']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Zaid McKie-Krisberg', 'raw_affiliation_strings': ['Brooklyn College of the City University of New York, Department of Biology, 2900 Bedford Avenue, New York, NY 11210, USA'], 'affiliations': [{'raw_affiliation_string': 'Brooklyn College of the City University of New York, Department of Biology, 2900 Bedford Avenue, New York, NY 11210, USA', 'institution_ids': ['https://openalex.org/I83041322', 'https://openalex.org/I174216632']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067328899', 'display_name': 'Jürgen E.W. Polle', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I83041322', 'display_name': 'Brooklyn College', 'ror': 'https://ror.org/019k4jq75', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I83041322']}, {'id': 'https://openalex.org/I174216632', 'display_name': 'City University of New York', 'ror': 'https://ror.org/00453a208', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I174216632']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jürgen E. W. Polle', 'raw_affiliation_strings': ['Brooklyn College of the City University of New York, Department of Biology, 2900 Bedford Avenue, New York, NY 11210, USA'], 'affiliations': [{'raw_affiliation_string': 'Brooklyn College of the City University of New York, Department of Biology, 2900 Bedford Avenue, New York, NY 11210, USA', 'institution_ids': ['https://openalex.org/I83041322', 'https://openalex.org/I174216632']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5036444315', 'display_name': 'Kai Sundmacher', 'orcid': 'https://orcid.org/0000-0003-3251-0593'}, 'institutions': [{'id': 'https://openalex.org/I95793202', 'display_name': 'Otto-von-Guericke University Magdeburg', 'ror': 'https://ror.org/00ggpsq73', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I95793202']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Kai Sundmacher', 'raw_affiliation_strings': ['Otto von Guericke University Magdeburg, Process Systems Engineering, Universitätsplatz 2, Magdeburg, 39106, Germany'], 'affiliations': [{'raw_affiliation_string': 'Otto von Guericke University Magdeburg, Process Systems Engineering, Universitätsplatz 2, Magdeburg, 39106, Germany', 'institution_ids': ['https://openalex.org/I95793202']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 1690, 'currency': 'GBP', 'value_usd': 2072, 'provenance': 'doaj'}, 'apc_paid': {'value': 1574, 'currency': 'EUR', 'value_usd': 1697, 'provenance': 'openapc'}, 'fwci': 4.07, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 103, 'citation_normalized_percentile': {'value': 0.999933, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '21', 'issue': '1', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10476', 'display_name': 'Algal biology and biofuel production', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2105', 'display_name': 'Renewable Energy, Sustainability and the Environment'}, 'field': {'id': 'https://openalex.org/fields/21', 'display_name': 'Energy'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10476', 'display_name': 'Algal biology and biofuel production', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2105', 'display_name': 'Renewable Energy, Sustainability and the Environment'}, 'field': {'id': 'https://openalex.org/fields/21', 'display_name': 'Energy'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10932', 'display_name': 'Microbial Metabolic Engineering and Bioproduction', 'score': 0.9915, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10303', 'display_name': 'Photosynthetic Processes and Mechanisms', 'score': 0.9788, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/dunaliella-salina', 'display_name': 'Dunaliella salina', 'score': 0.92298394}, {'id': 'https://openalex.org/keywords/flux-balance-analysis', 'display_name': 'Flux Balance Analysis', 'score': 0.7930563}, {'id': 'https://openalex.org/keywords/metabolic-network', 'display_name': 'Metabolic network', 'score': 0.7154834}, {'id': 'https://openalex.org/keywords/metabolic-flux-analysis', 'display_name': 'Metabolic flux analysis', 'score': 0.44437358}, {'id': 'https://openalex.org/keywords/metabolic-engineering', 'display_name': 'Metabolic Engineering', 'score': 0.441967}], 'concepts': [{'id': 'https://openalex.org/C2778159673', 'wikidata': 'https://www.wikidata.org/wiki/Q2441328', 'display_name': 'Dunaliella salina', 'level': 3, 'score': 0.92298394}, {'id': 'https://openalex.org/C167091322', 'wikidata': 'https://www.wikidata.org/wiki/Q5463029', 'display_name': 'Flux balance analysis', 'level': 2, 'score': 0.7930563}, {'id': 'https://openalex.org/C101810790', 'wikidata': 'https://www.wikidata.org/wiki/Q2263094', 'display_name': 'Metabolic network', 'level': 2, 'score': 0.7154834}, {'id': 'https://openalex.org/C89519541', 'wikidata': 'https://www.wikidata.org/wiki/Q4667893', 'display_name': 'Abiotic stress', 'level': 3, 'score': 0.48937196}, {'id': 'https://openalex.org/C68709404', 'wikidata': 'https://www.wikidata.org/wiki/Q1134475', 'display_name': 'Flux (metallurgy)', 'level': 2, 'score': 0.48916677}, {'id': 'https://openalex.org/C186060115', 'wikidata': 'https://www.wikidata.org/wiki/Q30336093', 'display_name': 'Biological system', 'level': 1, 'score': 0.47624946}, {'id': 'https://openalex.org/C160941953', 'wikidata': 'https://www.wikidata.org/wiki/Q6822342', 'display_name': 'Metabolic flux analysis', 'level': 3, 'score': 0.44437358}, {'id': 'https://openalex.org/C6350086', 'wikidata': 'https://www.wikidata.org/wiki/Q6822347', 'display_name': 'Metabolic engineering', 'level': 3, 'score': 0.441967}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.43184507}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.38043272}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.35015768}, {'id': 'https://openalex.org/C559758991', 'wikidata': 'https://www.wikidata.org/wiki/Q37868', 'display_name': 'Algae', 'level': 2, 'score': 0.32517833}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.29238176}, {'id': 'https://openalex.org/C59822182', 'wikidata': 'https://www.wikidata.org/wiki/Q441', 'display_name': 'Botany', 'level': 1, 'score': 0.2804426}, {'id': 'https://openalex.org/C62231903', 'wikidata': 'https://www.wikidata.org/wiki/Q1057', 'display_name': 'Metabolism', 'level': 2, 'score': 0.23213041}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.21893081}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.10856345}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002244', 'descriptor_name': 'Carbon', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000460', 'descriptor_name': 'Chlorophyta', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D058086', 'descriptor_name': 'Microalgae', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D002244', 'descriptor_name': 'Carbon', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D002244', 'descriptor_name': 'Carbon', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002338', 'descriptor_name': 'Carotenoids', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D002338', 'descriptor_name': 'Carotenoids', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002338', 'descriptor_name': 'Carotenoids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000460', 'descriptor_name': 'Chlorophyta', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000460', 'descriptor_name': 'Chlorophyta', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D000460', 'descriptor_name': 'Chlorophyta', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D002736', 'descriptor_name': 'Chloroplasts', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D002736', 'descriptor_name': 'Chloroplasts', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002736', 'descriptor_name': 'Chloroplasts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003600', 'descriptor_name': 'Cytosol', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D003600', 'descriptor_name': 'Cytosol', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D003600', 'descriptor_name': 'Cytosol', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008027', 'descriptor_name': 'Light', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053858', 'descriptor_name': 'Metabolic Networks and Pathways', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D058086', 'descriptor_name': 'Microalgae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D058086', 'descriptor_name': 'Microalgae', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D058086', 'descriptor_name': 'Microalgae', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D008954', 'descriptor_name': 'Models, Biological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013312', 'descriptor_name': 'Stress, Physiological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s12859-019-3325-0', 'pdf_url': 'https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-019-3325-0', 'source': {'id': 'https://openalex.org/S19032547', 'display_name': 'BMC Bioinformatics', 'issn_l': '1471-2105', 'issn': ['1471-2105'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/21.11116/0000-0005-D917-D', 'pdf_url': 'https://pure.mpg.de/pubman/item/item_3195370_4/component/file_3213262/fachet_3195370.pdf', 'source': {'id': 'https://openalex.org/S4306400655', 'display_name': 'MPG.PuRe (Max Planck Society)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I149899117', 'host_organization_name': 'Max Planck Society', 'host_organization_lineage': ['https://openalex.org/I149899117'], 'host_organization_lineage_names': ['Max Planck Society'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941287', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/31898485', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s12859-019-3325-0', 'pdf_url': 'https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-019-3325-0', 'source': {'id': 'https://openalex.org/S19032547', 'display_name': 'BMC Bioinformatics', 'issn_l': '1471-2105', 'issn': ['1471-2105'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/12', 'score': 0.43, 'display_name': 'Responsible consumption and production'}], 'grants': [], 'datasets': ['https://openalex.org/W4394409922', 'https://openalex.org/W4394374961'], 'versions': [], 'referenced_works_count': 54, 'referenced_works': ['https://openalex.org/W1505999767', 'https://openalex.org/W1576233366', 'https://openalex.org/W1766491408', 'https://openalex.org/W1972822989', 'https://openalex.org/W1973159958', 'https://openalex.org/W1980222019', 'https://openalex.org/W1998184313', 'https://openalex.org/W2004519536', 'https://openalex.org/W2018318238', 'https://openalex.org/W2018891073', 'https://openalex.org/W2019094033', 'https://openalex.org/W2019644045', 'https://openalex.org/W2020519829', 'https://openalex.org/W2025028179', 'https://openalex.org/W2031795005', 'https://openalex.org/W2043637181', 'https://openalex.org/W2065480158', 'https://openalex.org/W2066141057', 'https://openalex.org/W2069158406', 'https://openalex.org/W2076620665', 'https://openalex.org/W2082831560', 'https://openalex.org/W2099245389', 'https://openalex.org/W2108059426', 'https://openalex.org/W2110585362', 'https://openalex.org/W2114206363', 'https://openalex.org/W2118109148', 'https://openalex.org/W2125682435', 'https://openalex.org/W2127020923', 'https://openalex.org/W2133556195', 'https://openalex.org/W2139258915', 'https://openalex.org/W2149750593', 'https://openalex.org/W2155094521', 'https://openalex.org/W2160513026', 'https://openalex.org/W2161273903', 'https://openalex.org/W2164861153', 'https://openalex.org/W2170317108', 'https://openalex.org/W2171911221', 'https://openalex.org/W2215229013', 'https://openalex.org/W2325233624', 'https://openalex.org/W2372954600', 'https://openalex.org/W2485270400', 'https://openalex.org/W2532204570', 'https://openalex.org/W2532991125', 'https://openalex.org/W2549482207', 'https://openalex.org/W2572062069', 'https://openalex.org/W2725243226', 'https://openalex.org/W2731569610', 'https://openalex.org/W2765353327', 'https://openalex.org/W2790186428', 'https://openalex.org/W2792615677', 'https://openalex.org/W2802528759', 'https://openalex.org/W2802803660', 'https://openalex.org/W2888924758', 'https://openalex.org/W2897621869'], 'related_works': ['https://openalex.org/W4285237197', 'https://openalex.org/W3003302501', 'https://openalex.org/W2613838074', 'https://openalex.org/W2341681417', 'https://openalex.org/W2133150343', 'https://openalex.org/W2113329733', 'https://openalex.org/W2046546139', 'https://openalex.org/W1999460937', 'https://openalex.org/W1992844569', 'https://openalex.org/W1918238777'], 'abstract_inverted_index': {'The': [0, 76, 104], 'green': [1], 'microalga': [2], 'Dunaliella': [3], 'salina': [4, 38, 154], 'accumulates': [5], 'a': [6, 31, 60, 90], 'high': [7], 'proportion': [8], 'of': [9, 106, 118, 146, 152, 183], 'β-carotene': [10], 'during': [11], 'abiotic': [12], 'stress': [13, 170], 'conditions.': [14], 'To': [15], 'better': [16], 'understand': [17], 'the': [18, 43, 81, 107, 111, 116, 119, 130, 142, 163, 180], 'intracellular': [19], 'flux': [20, 91], 'distribution': [21], 'leading': [22], 'to': [23, 161, 174], 'carotenoid': [24], 'accumulation,': [25], 'this': [26, 157], 'work': [27, 158], 'aimed': [28], 'at': [29], 'reconstructing': [30], 'carbon': [32, 143], 'core': [33, 144], 'metabolic': [34, 150], 'network': [35, 61, 77, 121, 151], 'for': [36, 87, 97, 140, 179], 'D.': [37, 147, 153], 'CCAP': [39], '19/18': [40], 'based': [41], 'on': [42], 'recently': [44], 'published': [45], 'nuclear': [46], 'genome': [47], 'and': [48, 54, 66, 74, 85, 100, 125, 168, 171], 'its': [49], 'validation': [50], 'with': [51, 63, 110, 129], 'experimental': [52, 108], 'observations': [53], 'literature': [55], 'data.The': [56], 'reconstruction': [57], 'resulted': [58], 'in': [59, 80, 126, 156, 186], 'model': [62, 112, 135], '221': [64], 'reactions': [65], '212': [67], 'metabolites': [68], 'within': [69], 'three': [70], 'compartments:': [71], 'cytosol,': [72], 'chloroplast': [73], 'mitochondrion.': [75], 'was': [78, 94], 'implemented': [79], 'MATLAB': [82], 'toolbox': [83], 'CellNetAnalyzer': [84], 'checked': [86], 'feasibility.': [88], 'Furthermore,': [89], 'balance': [92], 'analysis': [93, 122], 'carried': [95], 'out': [96], 'different': [98], 'light': [99, 167], 'nutrient': [101, 169], 'uptake': [102], 'rates.': [103], 'comparison': [105], 'knowledge': [109], 'prediction': [113], 'revealed': [114], 'that': [115], 'results': [117], 'stoichiometric': [120], 'are': [123], 'plausible': [124], 'good': [127], 'agreement': [128], 'observed': [131], 'behavior.': [132], 'Accordingly,': [133], 'our': [134], 'provides': [136], 'an': [137, 175], 'excellent': [138], 'tool': [139], 'investigating': [141], 'metabolism': [145], 'salina.The': [148], 'reconstructed': [149], 'presented': [155], 'is': [159], 'able': [160], 'predict': [162], 'biological': [164], 'behavior': [165], 'under': [166], 'will': [172], 'lead': [173], 'improved': [176], 'process': [177], 'understanding': [178], 'optimized': [181], 'production': [182], 'high-value': [184], 'products': [185], 'microalgae.': [187]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3003302501', 'counts_by_year': [{'year': 2024, 'cited_by_count': 18}, {'year': 2023, 'cited_by_count': 20}, {'year': 2022, 'cited_by_count': 20}, {'year': 2021, 'cited_by_count': 35}, {'year': 2020, 'cited_by_count': 7}], 'updated_date': '2024-12-27T11:55:03.771632', 'created_date': '2020-02-07'}