Publication Information

{'id': 'https://openalex.org/W2995334721', 'doi': 'https://doi.org/10.1002/adhm.201901257', 'title': 'Modulating Macrophage Phenotype by Sustained MicroRNA Delivery Improves Host‐Implant Integration', 'display_name': 'Modulating Macrophage Phenotype by Sustained MicroRNA Delivery Improves Host‐Implant Integration', 'publication_year': 2019, 'publication_date': '2019-12-18', 'ids': {'openalex': 'https://openalex.org/W2995334721', 'doi': 'https://doi.org/10.1002/adhm.201901257', 'mag': '2995334721', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/31854130'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/adhm.201901257', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2500736452', 'display_name': 'Advanced Healthcare Materials', 'issn_l': '2192-2640', 'issn': ['2192-2640', '2192-2659'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://dr.ntu.edu.sg/bitstream/10356/142010/2/Modulating%20macrophage%20phenotype%20by%20sustained%20microRNA%20delivery%20improves%20hostimplant%20integration.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5035939511', 'display_name': 'Junquan Lin', 'orcid': 'https://orcid.org/0000-0002-0799-0583'}, 'institutions': [{'id': 'https://openalex.org/I172675005', 'display_name': 'Nanyang Technological University', 'ror': 'https://ror.org/02e7b5302', 'country_code': 'SG', 'type': 'education', 'lineage': ['https://openalex.org/I172675005']}], 'countries': ['SG'], 'is_corresponding': False, 'raw_author_name': 'Junquan Lin', 'raw_affiliation_strings': ['School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459 Singapore'], 'affiliations': [{'raw_affiliation_string': 'School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459 Singapore', 'institution_ids': ['https://openalex.org/I172675005']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039431130', 'display_name': 'Ibrahim M.A. Mohamed', 'orcid': 'https://orcid.org/0000-0002-7223-5808'}, 'institutions': [{'id': 'https://openalex.org/I4210153043', 'display_name': 'Duke University Hospital', 'ror': 'https://ror.org/04bct7p84', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210126298', 'https://openalex.org/I4210144876', 'https://openalex.org/I4210153043']}, {'id': 'https://openalex.org/I4210126298', 'display_name': 'Duke Medical Center', 'ror': 'https://ror.org/03njmea73', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210126298', 'https://openalex.org/I4210144876']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ibrahim Mohamed', 'raw_affiliation_strings': ['Division of Plastic and Reconstructive Surgery, Departments of Surgery and Pathology, Duke University Medical Center, Durham, NC, 27710 USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Plastic and Reconstructive Surgery, Departments of Surgery and Pathology, Duke University Medical Center, Durham, NC, 27710 USA', 'institution_ids': ['https://openalex.org/I4210153043', 'https://openalex.org/I4210126298']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5058162272', 'display_name': 'Po Hen Lin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I172675005', 'display_name': 'Nanyang Technological University', 'ror': 'https://ror.org/02e7b5302', 'country_code': 'SG', 'type': 'education', 'lineage': ['https://openalex.org/I172675005']}], 'countries': ['SG'], 'is_corresponding': False, 'raw_author_name': 'Po Hen Lin', 'raw_affiliation_strings': ['School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459 Singapore'], 'affiliations': [{'raw_affiliation_string': 'School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459 Singapore', 'institution_ids': ['https://openalex.org/I172675005']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045323520', 'display_name': 'Hitomi Shirahama', 'orcid': 'https://orcid.org/0000-0001-9710-0339'}, 'institutions': [{'id': 'https://openalex.org/I172675005', 'display_name': 'Nanyang Technological University', 'ror': 'https://ror.org/02e7b5302', 'country_code': 'SG', 'type': 'education', 'lineage': ['https://openalex.org/I172675005']}], 'countries': ['SG'], 'is_corresponding': False, 'raw_author_name': 'Hitomi Shirahama', 'raw_affiliation_strings': ['School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459 Singapore'], 'affiliations': [{'raw_affiliation_string': 'School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459 Singapore', 'institution_ids': ['https://openalex.org/I172675005']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029054194', 'display_name': 'Ulla Milbreta', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I172675005', 'display_name': 'Nanyang Technological University', 'ror': 'https://ror.org/02e7b5302', 'country_code': 'SG', 'type': 'education', 'lineage': ['https://openalex.org/I172675005']}], 'countries': ['SG'], 'is_corresponding': False, 'raw_author_name': 'Ulla Milbreta', 'raw_affiliation_strings': ['School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459 Singapore'], 'affiliations': [{'raw_affiliation_string': 'School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459 Singapore', 'institution_ids': ['https://openalex.org/I172675005']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034121073', 'display_name': 'Je Lin Sieow', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800824516', 'display_name': 'Singapore Immunology Network', 'ror': 'https://ror.org/03vmmgg57', 'country_code': 'SG', 'type': 'facility', 'lineage': ['https://openalex.org/I115228651', 'https://openalex.org/I2800824516', 'https://openalex.org/I2801752549']}], 'countries': ['SG'], 'is_corresponding': False, 'raw_author_name': 'Je Lin Sieow', 'raw_affiliation_strings': ['Singapore Immunology Network (SIgN), Biomedical Sciences Institute, ASTAR, Immunos, Singapore, 138648 Singapore'], 'affiliations': [{'raw_affiliation_string': 'Singapore Immunology Network (SIgN), Biomedical Sciences Institute, ASTAR, Immunos, Singapore, 138648 Singapore', 'institution_ids': ['https://openalex.org/I2800824516']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5082223258', 'display_name': 'Yanfen Peng', 'orcid': 'https://orcid.org/0000-0003-1753-8547'}, 'institutions': [{'id': 'https://openalex.org/I172675005', 'display_name': 'Nanyang Technological University', 'ror': 'https://ror.org/02e7b5302', 'country_code': 'SG', 'type': 'education', 'lineage': ['https://openalex.org/I172675005']}], 'countries': ['SG'], 'is_corresponding': False, 'raw_author_name': 'Yanfen Peng', 'raw_affiliation_strings': ['School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459 Singapore'], 'affiliations': [{'raw_affiliation_string': 'School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459 Singapore', 'institution_ids': ['https://openalex.org/I172675005']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030595673', 'display_name': 'Marianna Bugiani', 'orcid': 'https://orcid.org/0000-0001-7689-3042'}, 'institutions': [{'id': 'https://openalex.org/I4210108594', 'display_name': 'Amsterdam Neuroscience', 'ror': 'https://ror.org/01x2d9f70', 'country_code': 'NL', 'type': 'facility', 'lineage': ['https://openalex.org/I2802928900', 'https://openalex.org/I4210108594', 'https://openalex.org/I4210151833', 'https://openalex.org/I865915315', 'https://openalex.org/I887064364', 'https://openalex.org/I911458345']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Marianna Bugiani', 'raw_affiliation_strings': ['Departments of Child Neurology and Pathology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, 1081 HV The Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Departments of Child Neurology and Pathology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, 1081 HV The Netherlands', 'institution_ids': ['https://openalex.org/I4210108594']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007338010', 'display_name': 'Siew Cheng Wong', 'orcid': 'https://orcid.org/0000-0003-3979-6096'}, 'institutions': [{'id': 'https://openalex.org/I2800824516', 'display_name': 'Singapore Immunology Network', 'ror': 'https://ror.org/03vmmgg57', 'country_code': 'SG', 'type': 'facility', 'lineage': ['https://openalex.org/I115228651', 'https://openalex.org/I2800824516', 'https://openalex.org/I2801752549']}], 'countries': ['SG'], 'is_corresponding': False, 'raw_author_name': 'Siew Cheng Wong', 'raw_affiliation_strings': ['Singapore Immunology Network (SIgN), Biomedical Sciences Institute, ASTAR, Immunos, Singapore, 138648 Singapore'], 'affiliations': [{'raw_affiliation_string': 'Singapore Immunology Network (SIgN), Biomedical Sciences Institute, ASTAR, Immunos, Singapore, 138648 Singapore', 'institution_ids': ['https://openalex.org/I2800824516']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028626094', 'display_name': 'Howard Levinson', 'orcid': 'https://orcid.org/0000-0001-6962-3597'}, 'institutions': [{'id': 'https://openalex.org/I4210153043', 'display_name': 'Duke University Hospital', 'ror': 'https://ror.org/04bct7p84', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210126298', 'https://openalex.org/I4210144876', 'https://openalex.org/I4210153043']}, {'id': 'https://openalex.org/I4210126298', 'display_name': 'Duke Medical Center', 'ror': 'https://ror.org/03njmea73', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210126298', 'https://openalex.org/I4210144876']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Howard Levinson', 'raw_affiliation_strings': ['Department of Pathology, Duke University Medical Center, Durham, NC, 27710 USA', 'Division of Plastic and Reconstructive Surgery, Departments of Surgery and Pathology, Duke University Medical Center, Durham, NC, 27710 USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Plastic and Reconstructive Surgery, Departments of Surgery and Pathology, Duke University Medical Center, Durham, NC, 27710 USA', 'institution_ids': ['https://openalex.org/I4210153043', 'https://openalex.org/I4210126298']}, {'raw_affiliation_string': 'Department of Pathology, Duke University Medical Center, Durham, NC, 27710 USA', 'institution_ids': ['https://openalex.org/I4210153043', 'https://openalex.org/I4210126298']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5080348671', 'display_name': 'Sing Yian Chew', 'orcid': 'https://orcid.org/0000-0002-6084-5967'}, 'institutions': [{'id': 'https://openalex.org/I172675005', 'display_name': 'Nanyang Technological University', 'ror': 'https://ror.org/02e7b5302', 'country_code': 'SG', 'type': 'education', 'lineage': ['https://openalex.org/I172675005']}], 'countries': ['SG'], 'is_corresponding': True, 'raw_author_name': 'Sing Yian Chew', 'raw_affiliation_strings': ['Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232 Singapore', 'School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459 Singapore'], 'affiliations': [{'raw_affiliation_string': 'School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637459 Singapore', 'institution_ids': ['https://openalex.org/I172675005']}, {'raw_affiliation_string': 'Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232 Singapore', 'institution_ids': ['https://openalex.org/I172675005']}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 5, 'corresponding_author_ids': ['https://openalex.org/A5080348671'], 'corresponding_institution_ids': ['https://openalex.org/I172675005'], 'apc_list': {'value': 4430, 'currency': 'USD', 'value_usd': 4430, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.92, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 17, 'citation_normalized_percentile': {'value': 0.877226, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '9', 'issue': '3', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12264', 'display_name': 'Tissue Engineering and Regenerative Medicine', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12264', 'display_name': 'Tissue Engineering and Regenerative Medicine', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10729', 'display_name': 'Electrospun Nanofibers in Biomedical Applications', 'score': 0.9967, 'subfield': {'id': 'https://openalex.org/subfields/2502', 'display_name': 'Biomaterials'}, 'field': {'id': 'https://openalex.org/fields/25', 'display_name': 'Materials Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10059', 'display_name': 'Bone Tissue Engineering Materials', 'score': 0.9931, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/macrophage-polarization', 'display_name': 'Macrophage polarization', 'score': 0.8703902}, {'id': 'https://openalex.org/keywords/capsule', 'display_name': 'Capsule', 'score': 0.68005496}, {'id': 'https://openalex.org/keywords/m2-macrophage', 'display_name': 'M2 Macrophage', 'score': 0.65014434}], 'concepts': [{'id': 'https://openalex.org/C2776682551', 'wikidata': 'https://www.wikidata.org/wiki/Q21072584', 'display_name': 'Macrophage polarization', 'level': 4, 'score': 0.8703902}, {'id': 'https://openalex.org/C145059251', 'wikidata': 'https://www.wikidata.org/wiki/Q310899', 'display_name': 'microRNA', 'level': 3, 'score': 0.7112241}, {'id': 'https://openalex.org/C2778778583', 'wikidata': 'https://www.wikidata.org/wiki/Q147768', 'display_name': 'Capsule', 'level': 2, 'score': 0.68005496}, {'id': 'https://openalex.org/C2910375186', 'wikidata': 'https://www.wikidata.org/wiki/Q184204', 'display_name': 'M2 Macrophage', 'level': 4, 'score': 0.65014434}, {'id': 'https://openalex.org/C2781411149', 'wikidata': 'https://www.wikidata.org/wiki/Q486975', 'display_name': 'Implant', 'level': 2, 'score': 0.6415757}, {'id': 'https://openalex.org/C2779244956', 'wikidata': 'https://www.wikidata.org/wiki/Q184204', 'display_name': 'Macrophage', 'level': 3, 'score': 0.560606}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.44346672}, {'id': 'https://openalex.org/C91129048', 'wikidata': 'https://www.wikidata.org/wiki/Q594196', 'display_name': 'Nanofiber', 'level': 2, 'score': 0.43618858}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.38123173}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.38027382}, {'id': 'https://openalex.org/C192562407', 'wikidata': 'https://www.wikidata.org/wiki/Q228736', 'display_name': 'Materials science', 'level': 0, 'score': 0.3316704}, {'id': 'https://openalex.org/C136229726', 'wikidata': 'https://www.wikidata.org/wiki/Q327092', 'display_name': 'Biomedical engineering', 'level': 1, 'score': 0.32671118}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.25598937}, {'id': 'https://openalex.org/C171250308', 'wikidata': 'https://www.wikidata.org/wiki/Q11468', 'display_name': 'Nanotechnology', 'level': 1, 'score': 0.20588979}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.18585047}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.16333058}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.12384474}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.09639636}, {'id': 'https://openalex.org/C59822182', 'wikidata': 'https://www.wikidata.org/wiki/Q441', 'display_name': 'Botany', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D008264', 'descriptor_name': 'Macrophages', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D057139', 'descriptor_name': 'Nanofibers', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D019736', 'descriptor_name': 'Prostheses and Implants', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001808', 'descriptor_name': 'Blood Vessels', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': False}, {'descriptor_ui': 'D001808', 'descriptor_name': 'Blood Vessels', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005549', 'descriptor_name': 'Foreign-Body Reaction', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': False}, {'descriptor_ui': 'D005549', 'descriptor_name': 'Foreign-Body Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018014', 'descriptor_name': 'Gene Transfer Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008264', 'descriptor_name': 'Macrophages', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D008264', 'descriptor_name': 'Macrophages', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008810', 'descriptor_name': 'Mice, Inbred C57BL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D057139', 'descriptor_name': 'Nanofibers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010755', 'descriptor_name': 'Organophosphates', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D010755', 'descriptor_name': 'Organophosphates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011091', 'descriptor_name': 'Polyesters', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D011091', 'descriptor_name': 'Polyesters', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019736', 'descriptor_name': 'Prostheses and Implants', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/adhm.201901257', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2500736452', 'display_name': 'Advanced Healthcare Materials', 'issn_l': '2192-2640', 'issn': ['2192-2640', '2192-2659'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/10356/142010', 'pdf_url': 'https://dr.ntu.edu.sg/bitstream/10356/142010/2/Modulating%20macrophage%20phenotype%20by%20sustained%20microRNA%20delivery%20improves%20hostimplant%20integration.pdf', 'source': {'id': 'https://openalex.org/S4306402609', 'display_name': 'DR-NTU (Nanyang Technological University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I172675005', 'host_organization_name': 'Nanyang Technological University', 'host_organization_lineage': ['https://openalex.org/I172675005'], 'host_organization_lineage_names': ['Nanyang Technological University'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/31854130', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/10356/142010', 'pdf_url': 'https://dr.ntu.edu.sg/bitstream/10356/142010/2/Modulating%20macrophage%20phenotype%20by%20sustained%20microRNA%20delivery%20improves%20hostimplant%20integration.pdf', 'source': {'id': 'https://openalex.org/S4306402609', 'display_name': 'DR-NTU (Nanyang Technological University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I172675005', 'host_organization_name': 'Nanyang Technological University', 'host_organization_lineage': ['https://openalex.org/I172675005'], 'host_organization_lineage_names': ['Nanyang Technological University'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320320709', 'funder_display_name': 'National Research Foundation Singapore', 'award_id': 'NMRC/CBRG/0096/2015'}], 'datasets': [], 'versions': [], 'referenced_works_count': 49, 'referenced_works': ['https://openalex.org/W1475021316', 'https://openalex.org/W1482515349', 'https://openalex.org/W1648301895', 'https://openalex.org/W1797422316', 'https://openalex.org/W1927296860', 'https://openalex.org/W1975278509', 'https://openalex.org/W1977213877', 'https://openalex.org/W1986342542', 'https://openalex.org/W1995063875', 'https://openalex.org/W1999579326', 'https://openalex.org/W2007142798', 'https://openalex.org/W2018842062', 'https://openalex.org/W2019084643', 'https://openalex.org/W2022286567', 'https://openalex.org/W2032639324', 'https://openalex.org/W2036213518', 'https://openalex.org/W2036939733', 'https://openalex.org/W2053995348', 'https://openalex.org/W2055901626', 'https://openalex.org/W2056104115', 'https://openalex.org/W2057120576', 'https://openalex.org/W2058879644', 'https://openalex.org/W2065145765', 'https://openalex.org/W2066165358', 'https://openalex.org/W2085701716', 'https://openalex.org/W2090827542', 'https://openalex.org/W2098655765', 'https://openalex.org/W2099167250', 'https://openalex.org/W2100128950', 'https://openalex.org/W2103722820', 'https://openalex.org/W2106944257', 'https://openalex.org/W2107428754', 'https://openalex.org/W2110171090', 'https://openalex.org/W2123362076', 'https://openalex.org/W2123509232', 'https://openalex.org/W2126324756', 'https://openalex.org/W2141549067', 'https://openalex.org/W2151535331', 'https://openalex.org/W2156023352', 'https://openalex.org/W2168654563', 'https://openalex.org/W2303279577', 'https://openalex.org/W2412154595', 'https://openalex.org/W2533388171', 'https://openalex.org/W2554019942', 'https://openalex.org/W2562554519', 'https://openalex.org/W2587318156', 'https://openalex.org/W2588102691', 'https://openalex.org/W2807950737', 'https://openalex.org/W2884918620'], 'related_works': ['https://openalex.org/W4386033951', 'https://openalex.org/W4319060554', 'https://openalex.org/W3197706278', 'https://openalex.org/W3148703656', 'https://openalex.org/W3029971791', 'https://openalex.org/W2985630013', 'https://openalex.org/W2806617632', 'https://openalex.org/W2139804050', 'https://openalex.org/W1983073898', 'https://openalex.org/W1853146561'], 'abstract_inverted_index': {'Abstract': [0], 'Biomedical': [1], 'implant': [2], 'failure': [3], 'due': [4], 'to': [5, 75, 79, 115, 168, 179], 'the': [6, 15, 18, 26, 38, 49, 105, 125, 131, 134, 173], "host's": [7], 'response': [8], 'remains': [9], 'a': [10, 22, 57], 'challenging': [11], 'problem.': [12], 'In': [13], 'particular,': [14], 'formation': [16, 103], 'of': [17, 29, 41, 127, 162, 177], 'fibrous': [19, 101], 'capsule': [20, 102], 'is': [21, 33], 'common': [23], 'barrier': [24], 'for': [25, 60, 157], 'normal': [27], 'function': [28], 'implants.': [30], 'Currently,': [31], 'there': [32], 'mounting': [34], 'evidence': [35], 'indicating': [36], 'that': [37, 89, 124], 'polarization': [39, 82, 171], 'state': [40], 'macrophages': [42], 'plays': [43], 'an': [44], 'important': [45], 'role': [46], 'in': [47, 130, 136, 181, 184], 'effecting': [48], 'foreign': [50], 'body': [51], 'reaction': [52], '(FBR).': [53], 'This': [54], 'opens': [55], 'up': [56], 'potential': [58], 'avenue': [59], 'improving': [61], 'host‐implant': [62, 185], 'integration.': [63], 'Here,': [64], 'electrospun': [65], 'poly(caprolactone‐': [66], 'co': [67], '‐ethyl': [68], 'ethylene': [69], 'phosphate)': [70], 'nanofiber': [71, 153], 'scaffolds': [72, 106, 132, 154], 'are': [73, 90, 133, 155, 166], 'utilized': [74], 'deliver': [76], 'microRNAs': [77], '(miRs)': [78], 'induce': [80], 'macrophage': [81, 170], 'and': [83, 96, 111, 143, 159, 165], 'modulate': [84, 169], 'FBR.': [85], 'Specifically,': [86], 'C57BL/6': [87], 'mice': [88], 'treated': [91], 'with': [92, 117], 'M2‐inducing': [93], 'miRs,': [94], 'Let‐7c': [95, 144], 'miR‐124,': [97], 'display': [98], 'relatively': [99], 'thinner': [100], 'around': [104], 'at': [107, 187], 'both': [108], 'Week': [109], '2': [110, 175], '4,': [112], 'as': [113], 'compared': [114], 'treatment': [116, 138, 145], 'M1‐inducing': [118], 'miR,': [119], 'Anti‐Let‐7c.': [120], 'Histological': [121], 'analysis': [122], 'shows': [123], 'density': [126], 'blood': [128], 'vessels': [129], 'highest': [135], 'miR‐124': [137], 'group,': [139], 'followed': [140], 'by': [141], 'Anti‐Let‐7c': [142], 'groups.': [146], 'Based': [147], 'on': [148], 'immunohistochemical': [149], 'quantifications,': [150], 'these': [151], 'miR‐encapsulated': [152], 'useful': [156], 'localized': [158], 'sustained': [160], 'delivery': [161], 'functional': [163], 'miRs': [164], 'able': [167], 'during': [172], 'first': [174], 'weeks': [176], 'implantation': [178], 'result': [180], 'significant': [182], 'alteration': [183], 'integration': [186], 'longer': [188], 'time': [189], 'points.': [190]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2995334721', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 3}], 'updated_date': '2024-12-07T18:03:21.923008', 'created_date': '2019-12-26'}