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'https://openalex.org/W2188313369', 'https://openalex.org/W2310308624', 'https://openalex.org/W2336449782', 'https://openalex.org/W2608530032', 'https://openalex.org/W2621144715'], 'related_works': ['https://openalex.org/W96634583', 'https://openalex.org/W4389464116', 'https://openalex.org/W4282546241', 'https://openalex.org/W2564128998', 'https://openalex.org/W248873726', 'https://openalex.org/W2381509674', 'https://openalex.org/W2154565137', 'https://openalex.org/W2081010307', 'https://openalex.org/W1985574714', 'https://openalex.org/W1875572423'], 'abstract_inverted_index': {'Introduction:': [0], 'Polycystic': [1], 'ovary': [2], 'syndrome': [3], '(PCOS)': [4], 'involves': [5], 'expression': [6], 'of': [7, 12, 32, 46, 65, 74, 90, 118, 121, 132], 'chronic': [8], 'anovulation': [9], 'and': [10, 14, 51, 79, 86, 126, 129, 168], 'hyperandrogenism.Role': [11], 'environmental': [13], 'genetic': [15, 184], 'factors': [16], 'in': [17, 29, 57, 98, 115, 140, 165, 176], 'PCOS': [18, 34, 50, 100, 127, 142], 'is': [19, 187], 'strongly': [20], 'supported': [21], 'but': [22], 'the': [23, 30, 33, 58, 70, 99, 116, 124, 141], 'genes': [24, 76, 170], 'that': [25], 'are': [26], 'positively': [27], 'involved': [28], 'etiology': [31], 'have': [35, 182], 'not': [36, 113], 'been': [37], 'fully': [38], 'investigated': [39], 'until': [40], 'now.Material': [41], '&': [42], 'Methods:': [43], 'A': [44, 119], 'total': [45], '127': [47], 'patients': [48, 177], 'with': [49, 147, 178], '140': [52], 'healthy': [53], 'controls': [54, 103, 125, 146], 'were': [55, 81, 93, 135, 171], 'included': [56], 'present': [59], 'study.DNA': [60], 'was': [61, 112, 155], 'isolated': [62], 'from': [63, 68, 195], '4mL': [64], 'blood': [66], 'samples': [67], 'all': [69], 'enrolled': [71], 'subjects.The': [72], 'polymorphisms': [73], 'selected': [75], '(XRCC1,': [77], 'XPD': [78, 122, 167], 'hMSH2)': [80], 'carried': [82], 'out': [83], 'by': [84], 'ARMS-PCR': [85], 'PCR-RFLP.Results:': [87], 'GA': [88], 'genotype': [89], 'XRCC1': [91], 'gene': [92, 134], 'found': [94, 136, 172], 'to': [95, 102, 137, 145, 173, 189], 'be': [96, 138, 174], 'predominant': [97, 139, 175], 'compared': [101, 144], '(57.5%,': [104], '32.9%': [105], 'respectively,': [106], 'p': [107], '=': [108], '<0.0001).Signifi': [109], 'cant': [110, 158], 'difference': [111], 'observed': [114], 'frequency': [117], 'allele': [120], 'among': [123], '(0.76': [128], '0.62': [130], 'respectively).Heterozygotes': [131], 'hMSH2': [133, 169], 'group': [143], '2.64': [148], 'folds': [149], 'increased': [150], 'risk': [151], 'for': [152], 'PCOS,': [153], 'which': [154], 'statistically': [156], 'signifi': [157], '(OR': [159], '2.64,': [160], '95%': [161], 'CI': [162], '1.59-4.39,p=0.0001).Conclusions:': [163], 'Polymorphisms': [164], 'XRCC1,': [166], 'PCOS.Since': [179], 'different': [180], 'populations': [181], 'distinct': [183], 'backgrounds,': [185], 'it': [186], 'necessary': [188], 'validate': [190], 'or': [191], 'replicate': [192], 'such': [193], 'associations': [194], 'other': [196], 'ethnic': [197], 'populations.': [198]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2994101331', 'counts_by_year': [], 'updated_date': '2024-12-10T08:08:55.991602', 'created_date': '2019-12-13'}