Title: Procjena efektivne veličine populacije iz vezanih i nevezanih gena
Abstract: Effective population size (Ne) is a key population genetic parametar that describes the amount of genetic drift in a population. In other words, Ne is defined as the size of a hypothetically ideal population (N) that would experience the same amount of genetic change (genetic drift) as the real population we are considering. Estimation of effective population size (Ne) by the linkage disequilibrium (LD) method is increasingly used to estimation of population's parameters. However, due to the specificity of the formula, this assessment also includes markers that are not linked but only correlated (gametic disequilibrium – GD). Estimation of Ne by disequilibrium linked marker (NeLD) method is often used in population genetics of humans and domestic animals. On the contrary, the estimation of Ne from disequiliubrium unlinked markers information (NeGD) is often used in genetics of wild animals. This paper will seek to separate GD and LD and thus compare the estimates Ne with and without GD.
The aim of this paper is to estimate Ne by programs NeEstimator and SNeP. The estimates will then be compared because programs run on different algorithms. The paper uses data from six sheep populations with a total of 354 individuals.
Publication Year: 2019
Publication Date: 2019-09-30
Language: en
Type: dissertation
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