Screening of House Dust from Chinese Homes for Chemicals with Liver X Receptors Binding Activities and Characterization of Atherosclerotic Activity Using an <i>in Vitro</i> Macrophage Cell Line and ApoE−/− Mice

Name: Work Video:
Duration: 3 min 30 s
Wenxin Hu; Yingting Jia; Qiyue Kang; Hui Peng; Haojia Ma; Shiyi Zhang; Youhei Hiromori; Tomoki Kimura; Tsuyoshi Nakanishi; Lemin Zheng; Yifu Qiu; Zhaobin Zhang; Yi Wan; Jianying Hu
{'id': 'https://openalex.org/W2984392772', 'doi': 'https://doi.org/10.1289/ehp5039', 'title': 'Screening of House Dust from Chinese Homes for Chemicals with Liver X Receptors Binding Activities and Characterization of Atherosclerotic Activity Using an <i>in Vitro</i> Macrophage Cell Line and ApoE−/− Mice', 'display_name': 'Screening of House Dust from Chinese Homes for Chemicals with Liver X Receptors Binding Activities and Characterization of Atherosclerotic Activity Using an <i>in Vitro</i> Macrophage Cell Line and ApoE−/− Mice', 'publication_year': 2019, 'publication_date': '2019-11-01', 'ids': {'openalex': 'https://openalex.org/W2984392772', 'doi': 'https://doi.org/10.1289/ehp5039', 'mag': '2984392772', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/31724879', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6927504'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1289/ehp5039', 'pdf_url': 'https://ehp.niehs.nih.gov/doi/pdf/10.1289/EHP5039', 'source': {'id': 'https://openalex.org/S10446503', 'display_name': 'Environmental Health Perspectives', 'issn_l': '0091-6765', 'issn': ['0091-6765', '1552-9924'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319799', 'host_organization_name': 'National Institute of Environmental Health Sciences', 'host_organization_lineage': ['https://openalex.org/P4310319799', 'https://openalex.org/P4310316754'], 'host_organization_lineage_names': ['National Institute of Environmental Health Sciences', 'National Institutes of Health'], 'type': 'journal'}, 'license': 'public-domain', 'license_id': 'https://openalex.org/licenses/public-domain', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'diamond', 'oa_url': 'https://ehp.niehs.nih.gov/doi/pdf/10.1289/EHP5039', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5102800609', 'display_name': 'Wenxin Hu', 'orcid': 'https://orcid.org/0000-0002-7339-6443'}, 'institutions': [{'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wenxin Hu', 'raw_affiliation_strings': ['Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, China', 'institution_ids': ['https://openalex.org/I20231570']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060845432', 'display_name': 'Yingting Jia', 'orcid': 'https://orcid.org/0000-0003-0433-1619'}, 'institutions': [{'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yingting Jia', 'raw_affiliation_strings': ['Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, China', 'institution_ids': ['https://openalex.org/I20231570']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018296464', 'display_name': 'Qiyue Kang', 'orcid': 'https://orcid.org/0000-0003-2028-084X'}, 'institutions': [{'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Qiyue Kang', 'raw_affiliation_strings': ['Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, China', 'institution_ids': ['https://openalex.org/I20231570']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5043920362', 'display_name': 'Hui Peng', 'orcid': 'https://orcid.org/0000-0002-2000-1647'}, 'institutions': [{'id': 'https://openalex.org/I185261750', 'display_name': 'University of Toronto', 'ror': 'https://ror.org/03dbr7087', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I185261750']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Hui Peng', 'raw_affiliation_strings': ['Department of Chemistry, University of Toronto, Toronto, Ontario, Canada'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, University of Toronto, Toronto, Ontario, Canada', 'institution_ids': ['https://openalex.org/I185261750']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080708277', 'display_name': 'Haojia Ma', 'orcid': 'https://orcid.org/0009-0002-9215-4690'}, 'institutions': [{'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Haojia Ma', 'raw_affiliation_strings': ['Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, China', 'institution_ids': ['https://openalex.org/I20231570']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100784919', 'display_name': 'Shiyi Zhang', 'orcid': 'https://orcid.org/0000-0003-3942-7928'}, 'institutions': [{'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Shiyi Zhang', 'raw_affiliation_strings': ['Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, China', 'institution_ids': ['https://openalex.org/I20231570']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5062431954', 'display_name': 'Youhei Hiromori', 'orcid': 'https://orcid.org/0009-0007-4381-6201'}, 'institutions': [{'id': 'https://openalex.org/I173865709', 'display_name': 'Gifu Pharmaceutical University', 'ror': 'https://ror.org/0372t5741', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I173865709']}, {'id': 'https://openalex.org/I171559596', 'display_name': 'Suzuka University of Medical Science', 'ror': 'https://ror.org/00tq7xg10', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I171559596']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Youhei Hiromori', 'raw_affiliation_strings': ['Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science, Suzuka, Mie, Japan', 'Laboratory of Hygienic Chemistry and Molecular Toxicology, Gifu Pharmaceutical University, Gifu, Gifu, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Hygienic Chemistry and Molecular Toxicology, Gifu Pharmaceutical University, Gifu, Gifu, Japan', 'institution_ids': ['https://openalex.org/I173865709']}, {'raw_affiliation_string': 'Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science, Suzuka, Mie, Japan', 'institution_ids': ['https://openalex.org/I171559596']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055653919', 'display_name': 'Tomoki Kimura', 'orcid': 'https://orcid.org/0000-0002-5138-5882'}, 'institutions': [{'id': 'https://openalex.org/I102826571', 'display_name': 'Setsunan University', 'ror': 'https://ror.org/0418a3v02', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I102826571']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tomoki Kimura', 'raw_affiliation_strings': ['Department of Life Science, Faculty of Science and Engineering, Setsunan University, Ikedanakamachi, Neyagawa, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Life Science, Faculty of Science and Engineering, Setsunan University, Ikedanakamachi, Neyagawa, Japan', 'institution_ids': ['https://openalex.org/I102826571']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101739606', 'display_name': 'Tsuyoshi Nakanishi', 'orcid': 'https://orcid.org/0000-0002-2683-0075'}, 'institutions': [{'id': 'https://openalex.org/I173865709', 'display_name': 'Gifu Pharmaceutical University', 'ror': 'https://ror.org/0372t5741', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I173865709']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tsuyoshi Nakanishi', 'raw_affiliation_strings': ['Laboratory of Hygienic Chemistry and Molecular Toxicology, Gifu Pharmaceutical University, Gifu, Gifu, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Hygienic Chemistry and Molecular Toxicology, Gifu Pharmaceutical University, Gifu, Gifu, Japan', 'institution_ids': ['https://openalex.org/I173865709']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101751176', 'display_name': 'Lemin Zheng', 'orcid': 'https://orcid.org/0000-0003-4473-6936'}, 'institutions': [{'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Lemin Zheng', 'raw_affiliation_strings': ['School of Basic Medical Sciences, Peking University Health Science Center, Peking University, Beijing, China'], 'affiliations': [{'raw_affiliation_string': 'School of Basic Medical Sciences, Peking University Health Science Center, Peking University, Beijing, China', 'institution_ids': ['https://openalex.org/I20231570']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067879712', 'display_name': 'Yifu Qiu', 'orcid': 'https://orcid.org/0000-0001-5645-3189'}, 'institutions': [{'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yifu Qiu', 'raw_affiliation_strings': ['Institute of Molecular Medicine, Peking University, Beijing, China'], 'affiliations': [{'raw_affiliation_string': 'Institute of Molecular Medicine, Peking University, Beijing, China', 'institution_ids': ['https://openalex.org/I20231570']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001479419', 'display_name': 'Zhaobin Zhang', 'orcid': 'https://orcid.org/0000-0003-0838-0872'}, 'institutions': [{'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhaobin Zhang', 'raw_affiliation_strings': ['Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, China', 'institution_ids': ['https://openalex.org/I20231570']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101682794', 'display_name': 'Yi Wan', 'orcid': 'https://orcid.org/0000-0003-1312-6254'}, 'institutions': [{'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yi Wan', 'raw_affiliation_strings': ['Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, China', 'institution_ids': ['https://openalex.org/I20231570']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5010492003', 'display_name': 'Jianying Hu', 'orcid': 'https://orcid.org/0000-0003-1965-7494'}, 'institutions': [{'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jianying Hu', 'raw_affiliation_strings': ['Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, China', 'institution_ids': ['https://openalex.org/I20231570']}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 0, 'currency': 'USD', 'value_usd': 0, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.265, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 63, 'citation_normalized_percentile': {'value': 0.760109, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '127', 'issue': '11', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10190', 'display_name': 'Air Quality and Health Impacts', 'score': 0.9605, 'subfield': {'id': 'https://openalex.org/subfields/2307', 'display_name': 'Health, Toxicology and Mutagenesis'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10190', 'display_name': 'Air Quality and Health Impacts', 'score': 0.9605, 'subfield': {'id': 'https://openalex.org/subfields/2307', 'display_name': 'Health, Toxicology and Mutagenesis'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/liver-x-receptor', 'display_name': 'Liver X receptor', 'score': 0.8724514}, {'id': 'https://openalex.org/keywords/foam-cell', 'display_name': 'Foam cell', 'score': 0.5964141}, {'id': 'https://openalex.org/keywords/abcg1', 'display_name': 'ABCG1', 'score': 0.55951124}], 'concepts': [{'id': 'https://openalex.org/C167400880', 'wikidata': 'https://www.wikidata.org/wiki/Q3454539', 'display_name': 'Liver X receptor', 'level': 5, 'score': 0.8724514}, {'id': 'https://openalex.org/C2777704780', 'wikidata': 'https://www.wikidata.org/wiki/Q21115210', 'display_name': 'ABCA1', 'level': 4, 'score': 0.672371}, {'id': 'https://openalex.org/C2777895019', 'wikidata': 'https://www.wikidata.org/wiki/Q1425962', 'display_name': 'Foam cell', 'level': 4, 'score': 0.5964141}, {'id': 'https://openalex.org/C207001950', 'wikidata': 'https://www.wikidata.org/wiki/Q141124', 'display_name': 'In vivo', 'level': 2, 'score': 0.5862284}, {'id': 'https://openalex.org/C2776330080', 'wikidata': 'https://www.wikidata.org/wiki/Q21113668', 'display_name': 'ABCG1', 'level': 5, 'score': 0.55951124}, {'id': 'https://openalex.org/C2779244956', 'wikidata': 'https://www.wikidata.org/wiki/Q184204', 'display_name': 'Macrophage', 'level': 3, 'score': 0.46213737}, {'id': 'https://openalex.org/C2778163477', 'wikidata': 'https://www.wikidata.org/wiki/Q43656', 'display_name': 'Cholesterol', 'level': 2, 'score': 0.45107666}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.41951743}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.37510878}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.37178928}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.34737778}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3360495}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.3346415}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.273333}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.2261281}, {'id': 'https://openalex.org/C63932345', 'wikidata': 'https://www.wikidata.org/wiki/Q422500', 'display_name': 'Nuclear receptor', 'level': 4, 'score': 0.10813135}, {'id': 'https://openalex.org/C150903083', 'wikidata': 'https://www.wikidata.org/wiki/Q7108', 'display_name': 'Biotechnology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C149011108', 'wikidata': 'https://www.wikidata.org/wiki/Q652985', 'display_name': 'Transporter', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000393', 'descriptor_name': 'Air Pollutants', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D016902', 'descriptor_name': 'Air Pollution, Indoor', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D050197', 'descriptor_name': 'Atherosclerosis', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D004391', 'descriptor_name': 'Dust', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D000393', 'descriptor_name': 'Air Pollutants', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016902', 'descriptor_name': 'Air Pollution, Indoor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050197', 'descriptor_name': 'Atherosclerosis', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': False}, {'descriptor_ui': 'D050197', 'descriptor_name': 'Atherosclerosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002681', 'descriptor_name': 'China', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004391', 'descriptor_name': 'Dust', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000071518', 'descriptor_name': 'Liver X Receptors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000071518', 'descriptor_name': 'Liver X Receptors', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008810', 'descriptor_name': 'Mice, Inbred C57BL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000074085', 'descriptor_name': 'Mice, Knockout, ApoE', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000067996', 'descriptor_name': 'RAW 264.7 Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1289/ehp5039', 'pdf_url': 'https://ehp.niehs.nih.gov/doi/pdf/10.1289/EHP5039', 'source': {'id': 'https://openalex.org/S10446503', 'display_name': 'Environmental Health Perspectives', 'issn_l': '0091-6765', 'issn': ['0091-6765', '1552-9924'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319799', 'host_organization_name': 'National Institute of Environmental Health Sciences', 'host_organization_lineage': ['https://openalex.org/P4310319799', 'https://openalex.org/P4310316754'], 'host_organization_lineage_names': ['National Institute of Environmental Health Sciences', 'National Institutes of Health'], 'type': 'journal'}, 'license': 'public-domain', 'license_id': 'https://openalex.org/licenses/public-domain', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc6927504', 'pdf_url': 'https://europepmc.org/articles/pmc6927504?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927504', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/31724879', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1289/ehp5039', 'pdf_url': 'https://ehp.niehs.nih.gov/doi/pdf/10.1289/EHP5039', 'source': {'id': 'https://openalex.org/S10446503', 'display_name': 'Environmental Health Perspectives', 'issn_l': '0091-6765', 'issn': ['0091-6765', '1552-9924'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319799', 'host_organization_name': 'National Institute of Environmental Health Sciences', 'host_organization_lineage': ['https://openalex.org/P4310319799', 'https://openalex.org/P4310316754'], 'host_organization_lineage_names': ['National Institute of Environmental Health Sciences', 'National Institutes of Health'], 'type': 'journal'}, 'license': 'public-domain', 'license_id': 'https://openalex.org/licenses/public-domain', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.42}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 50, 'referenced_works': ['https://openalex.org/W1149349272', 'https://openalex.org/W1526302359', 'https://openalex.org/W1650965741', 'https://openalex.org/W1973402545', 'https://openalex.org/W1974864595', 'https://openalex.org/W1985370990', 'https://openalex.org/W1986755882', 'https://openalex.org/W1994712205', 'https://openalex.org/W2012154384', 'https://openalex.org/W2012690683', 'https://openalex.org/W2025165872', 'https://openalex.org/W2026236910', 'https://openalex.org/W2026587556', 'https://openalex.org/W2031672510', 'https://openalex.org/W2036700466', 'https://openalex.org/W2038699706', 'https://openalex.org/W2052435494', 'https://openalex.org/W2086290312', 'https://openalex.org/W2091358061', 'https://openalex.org/W2092206838', 'https://openalex.org/W2097511872', 'https://openalex.org/W2099335802', 'https://openalex.org/W2099540110', 'https://openalex.org/W2101415872', 'https://openalex.org/W2102848212', 'https://openalex.org/W2103714932', 'https://openalex.org/W2104016841', 'https://openalex.org/W2114328455', 'https://openalex.org/W2116237065', 'https://openalex.org/W2119092533', 'https://openalex.org/W2121731956', 'https://openalex.org/W2147881974', 'https://openalex.org/W2157098333', 'https://openalex.org/W2159332620', 'https://openalex.org/W2165104851', 'https://openalex.org/W2165534314', 'https://openalex.org/W2166169043', 'https://openalex.org/W2326186065', 'https://openalex.org/W2419499011', 'https://openalex.org/W2435738159', 'https://openalex.org/W2593494248', 'https://openalex.org/W2595709889', 'https://openalex.org/W2735193701', 'https://openalex.org/W2738798374', 'https://openalex.org/W2759742128', 'https://openalex.org/W2906034961', 'https://openalex.org/W2969166360', 'https://openalex.org/W3140799612', 'https://openalex.org/W4211200033', 'https://openalex.org/W4237409398'], 'related_works': ['https://openalex.org/W4236404449', 'https://openalex.org/W3048895920', 'https://openalex.org/W2405007220', 'https://openalex.org/W2331166879', 'https://openalex.org/W2160015677', 'https://openalex.org/W2094753712', 'https://openalex.org/W2038314830', 'https://openalex.org/W1990488222', 'https://openalex.org/W1984008992', 'https://openalex.org/W1980848916'], 'abstract_inverted_index': {'Vol.': [0], '127,': [1], 'No.': [2], '11': [3, 1543, 3617, 3659, 3810], 'ResearchOpen': [4], 'AccessScreening': [5], 'of': [6, 22, 72, 97, 122, 142, 145, 166, 191, 211, 224, 229, 246, 250, 270, 293, 317, 340, 365, 396, 419, 456, 483, 490, 587, 632, 638, 677, 684, 694, 712, 721, 738, 781, 813, 829, 839, 872, 888, 907, 974, 990, 1001, 1103, 1150, 1165, 1186, 1213, 1215, 1257, 1280, 1291, 1302, 1313, 1324, 1360, 1419, 1490, 1504, 1511, 1538, 1594, 1650, 1673, 1722, 1729, 1802, 1819, 1865, 1909, 1927, 2064, 2090, 2111, 2137, 2152, 2156, 2170, 2174, 2210, 2216, 2309, 2363, 2409, 2569, 2572, 2582, 2594, 2618, 2638, 2650, 2655, 2661, 2666, 2688, 2727, 2750, 2762, 2819, 2829, 2840, 2842, 2876, 2923, 2952, 2959, 3002, 3016, 3088, 3112, 3187, 3196, 3213, 3221, 3514, 3605, 3647, 3791, 3897, 3901, 3993, 4136, 4305, 4394, 4404, 4450], 'House': [7], 'Dust': [8, 1189], 'from': [9, 553, 680, 1204, 1233, 1252, 1295, 1306, 1317, 1328, 1336, 1344, 1356, 1396, 1542, 1602, 1647, 1850, 1986, 2104, 2244, 2256, 2996, 3026, 3043, 3893, 4103, 4233], 'Chinese': [10, 554, 681, 1217], 'Homes': [11], 'for': [12, 67, 82, 92, 107, 117, 132, 151, 161, 176, 186, 201, 236, 260, 283, 307, 325, 335, 350, 360, 375, 391, 414, 429, 468, 556, 569, 1230, 1433, 1443, 1451, 1500, 1530, 1559, 1564, 1578, 1664, 1757, 1782, 1787, 1795, 1833, 1921, 1943, 2042, 2050, 2071, 2204, 2264, 2280, 2283, 2398, 2416, 2499, 2558, 2722, 2737, 2862, 2867, 3083, 3092, 3096, 3101, 3107, 3116, 3120, 3125, 3177, 3184, 3210, 3298, 3316, 3329, 3350, 3403, 3466, 3478, 3510, 3523, 3546, 3637, 3642, 3680, 3685, 3745, 3750, 3772, 3777, 3815, 3820, 3844, 3849, 3908, 3913, 4010, 4049, 4151, 4185, 4196, 4280, 4340], 'Chemicals': [13], 'with': [14, 977, 1049, 1071, 1425, 1670, 1704, 1734, 1825, 1841, 1879, 1890, 1907, 1968, 1993, 2086, 2481, 2590, 2597, 2605, 2707, 2717, 2748, 3145, 3152, 3166, 3306, 3399, 3428, 3469, 3497, 3614, 3656, 3709, 3807, 3852, 3943, 3983, 4020, 4039, 4144, 4157, 4272, 4322, 4329, 4353], 'Liver': [15, 470, 922], 'X': [16, 471, 923], 'Receptors': [17], 'Binding': [18], 'Activities': [19], 'and': [20, 32, 61, 74, 99, 124, 168, 193, 214, 252, 273, 342, 367, 382, 398, 421, 459, 486, 525, 541, 558, 576, 592, 594, 614, 623, 648, 656, 660, 730, 763, 788, 791, 798, 846, 855, 904, 919, 929, 952, 958, 987, 997, 1106, 1122, 1134, 1143, 1145, 1148, 1152, 1172, 1192, 1210, 1266, 1273, 1275, 1333, 1362, 1373, 1388, 1391, 1440, 1471, 1494, 1506, 1518, 1597, 1611, 1680, 1725, 1742, 1790, 1882, 1885, 1901, 1913, 1974, 1980, 2002, 2030, 2045, 2067, 2131, 2134, 2143, 2166, 2227, 2260, 2293, 2303, 2323, 2335, 2344, 2346, 2356, 2394, 2412, 2418, 2429, 2434, 2443, 2459, 2467, 2475, 2479, 2489, 2511, 2517, 2522, 2535, 2629, 2657, 2705, 2730, 2742, 2764, 2781, 2813, 2816, 2831, 2844, 2864, 2884, 2956, 2964, 2977, 2992, 3006, 3010, 3041, 3079, 3099, 3123, 3135, 3149, 3193, 3294, 3310, 3343, 3376, 3443, 3519, 3552, 3569, 3577, 3592, 3616, 3639, 3658, 3682, 3711, 3747, 3752, 3767, 3774, 3794, 3809, 3817, 3822, 3846, 3888, 3904, 3961, 3971, 3979, 4013, 4025, 4059, 4106, 4134, 4154, 4179, 4231, 4237, 4245, 4252, 4270, 4277, 4289, 4295, 4326, 4348, 4362, 4383, 4421, 4429, 4440], 'Characterization': [21], 'Atherosclerotic': [23], 'Activity': [24], 'Using': [25, 1607], 'an': [26, 532, 603, 1139, 1437, 2039, 2794, 4087], 'in': [27, 478, 506, 517, 521, 523, 529, 531, 564, 580, 600, 619, 653, 666, 674, 697, 714, 727, 749, 753, 757, 766, 770, 772, 826, 843, 853, 869, 915, 954, 1003, 1019, 1097, 1138, 1155, 1160, 1179, 1197, 1246, 1254, 1271, 1370, 1496, 1520, 1548, 1915, 1946, 2014, 2069, 2160, 2178, 2249, 2485, 2493, 2504, 2513, 2524, 2575, 2585, 2600, 2609, 2692, 2766, 2777, 2835, 2893, 2983, 3204, 3230, 3248, 3273, 3340, 3362, 3430, 3450, 3867, 4033, 4264, 4359, 4396, 4415], 'Vitro': [28], 'Macrophage': [29], 'Cell': [30, 3898, 4072, 4406], 'Line': [31, 3899], 'ApoE−/−': [33, 534, 604, 668, 699], 'Mice': [34], 'Wenxin': [35, 64], 'Hu,': [36, 389], 'Yingting': [37, 89], 'Jia,': [38], 'Qiyue': [39, 114], 'Kang,': [40], 'Hui': [41, 139], 'Peng,': [42], 'Haojia': [43, 158], 'Ma,': [44], 'Shiyi': [45, 183], 'Zhang,': [46, 58], 'Youhei': [47, 208], 'Hiromori,': [48], 'Tomoki': [49, 243], 'Kimura,': [50], 'Tsuyoshi': [51, 267], 'Nakanishi,': [52], 'Lemin': [53, 290], 'Zheng,': [54], 'Yifu': [55, 314], 'Qiu,': [56], 'Zhaobin': [57, 332], 'Yi': [59, 357], 'Wan,': [60], 'Jianying': [62, 383, 388], 'Hu': [63, 65, 384], 'Laboratory': [66, 91, 116, 160, 185, 210, 269, 334, 359, 390, 413], 'Earth': [68, 93, 118, 162, 187, 336, 361, 392, 415], 'Surface': [69, 94, 119, 163, 188, 337, 362, 393, 416], 'Processes,': [70, 95, 120, 164, 189, 338, 363, 394, 417], 'College': [71, 96, 121, 165, 190, 339, 364, 395, 418], 'Urban': [73, 98, 123, 167, 192, 341, 366, 397, 420], 'Environmental': [75, 100, 125, 169, 194, 343, 368, 399, 422], 'Sciences,': [76, 101, 126, 170, 195, 226, 296, 344, 369, 400, 423], 'Peking': [77, 102, 127, 171, 196, 297, 302, 320, 345, 370, 401, 424, 1595], 'University,': [78, 103, 128, 172, 197, 219, 255, 278, 303, 321, 346, 371, 402, 425, 1596], 'Beijing,': [79, 104, 129, 173, 198, 304, 322, 347, 372, 426, 1260, 3902], 'China': [80, 105, 130, 174, 199, 305, 323, 348, 373, 427, 771, 1258], 'Search': [81, 106, 131, 150, 175, 200, 235, 259, 282, 306, 324, 349, 374, 428], 'more': [83, 108, 133, 152, 177, 202, 237, 261, 284, 308, 326, 351, 376, 430], 'papers': [84, 109, 134, 153, 178, 203, 238, 262, 285, 309, 327, 352, 377, 431], 'by': [85, 110, 135, 154, 179, 204, 239, 263, 286, 310, 328, 353, 378, 432, 936, 1017, 1055, 1077, 1278, 1400, 1431, 1590, 1626, 1643, 1772, 1813, 1854, 1869, 2025, 2036, 2214, 2636, 2880, 2908, 2943, 2969, 3031, 3067, 3173, 3236, 3312, 3485, 3530, 3560, 3609, 3651, 3704, 3727, 3740, 3802, 4217, 4223], 'this': [86, 111, 136, 155, 180, 205, 240, 264, 287, 311, 329, 354, 379, 433, 515, 565, 1083, 1085, 1198, 2505], 'author': [87, 112, 137, 156, 181, 206, 241, 265, 288, 312, 330, 355, 380, 434], ',': [88, 113, 138, 157, 182, 207, 242, 266, 289, 313, 331, 356, 381], 'Jia': [90], 'Kang': [115], 'Peng': [140], 'Department': [141, 245], 'Chemistry,': [143], 'University': [144, 228, 298, 1649], 'Toronto,': [146, 147], 'Ontario,': [148], 'Canada': [149], 'Ma': [159], 'Zhang': [184, 333], 'Hiromori': [209], 'Hygienic': [212, 271], 'Chemistry': [213, 272], 'Molecular': [215, 274, 318], 'Toxicology,': [216, 275], 'Gifu': [217, 276], 'Pharmaceutical': [218, 225, 277], 'Gifu,': [220, 221, 279, 280], 'Japan': [222, 234, 258, 281], 'Faculty': [223, 249], 'Suzuka': [227], 'Medical': [230, 295, 1653], 'Science,': [231, 248], 'Suzuka,': [232], 'Mie,': [233], 'Kimura': [244], 'Life': [247, 1934, 4125], 'Science': [251, 300], 'Engineering,': [253], 'Setsunan': [254], 'Ikedanakamachi,': [256], 'Neyagawa,': [257], 'Nakanishi': [268], 'Zheng': [291], 'School': [292], 'Basic': [294], 'Health': [299], 'Center,': [301, 1654], 'Qiu': [315], 'Institute': [316, 1359], 'Medicine,': [319], 'Wan': [358], 'Address': [385], 'correspondence': [386], 'to': [387, 499, 513, 519, 548, 572, 583, 596, 627, 636, 690, 707, 747, 764, 786, 819, 945, 1012, 1032, 1064, 1069, 1089, 1297, 1308, 1319, 1330, 1339, 1346, 1459, 1468, 1483, 1515, 1523, 1554, 1581, 1713, 1748, 1793, 1860, 1936, 2019, 2057, 2099, 2115, 2246, 2258, 2273, 2299, 2368, 2374, 2391, 2440, 2579, 2684, 2702, 2754, 2800, 2888, 2937, 2948, 3200, 3226, 3265, 3454, 3633, 3676, 3760, 3858, 3932, 4114, 4129, 4400], 'Beijing': [403], '10087': [404], 'China.': [405], 'Telephone:': [406], '86-10-62765520.': [407], 'Email:': [408], 'E-mail': [409], 'Address:': [410], '[email': [411], 'protected]': [412], 'Published:14': [435], 'November': [436], '2019CID:': [437], '117003https://doi.org/10.1289/EHP5039Cited': [438], 'by:11AboutSectionsPDF': [439], 'Supplemental': [440], 'Materials': [441], 'ToolsDownload': [442], 'CitationsTrack': [443], 'Citations': [444], 'ShareShare': [445], 'onFacebookTwitterLinked': [446], 'InRedditEmail': [447], 'AbstractBackground:Atherosclerotic': [448], 'cardiovascular': [449, 526, 722, 878], 'disease': [450, 527, 723], 'has': [451, 725, 732], 'become': [452], 'the': [453, 585, 608, 639, 667, 685, 692, 698, 705, 709, 734, 754, 827, 873, 897, 905, 927, 1013, 1156, 1184, 1205, 1211, 1288, 1292, 1300, 1303, 1311, 1314, 1322, 1325, 1334, 1337, 1340, 1357, 1397, 1454, 1472, 1502, 1531, 1539, 1561, 1571, 1591, 1616, 1619, 1648, 1698, 1707, 1714, 1719, 1726, 1744, 1760, 1886, 1896, 1939, 1957, 1963, 1987, 2020, 2082, 2105, 2112, 2122, 2135, 2157, 2161, 2167, 2175, 2179, 2205, 2234, 2240, 2252, 2268, 2274, 2307, 2315, 2324, 2332, 2337, 2379, 2406, 2422, 2430, 2486, 2494, 2514, 2525, 2530, 2533, 2546, 2567, 2570, 2576, 2580, 2586, 2601, 2606, 2610, 2643, 2647, 2658, 2664, 2686, 2689, 2693, 2697, 2718, 2743, 2751, 2760, 2767, 2771, 2782, 2786, 2789, 2801, 2838, 2849, 2856, 2874, 2877, 2881, 2885, 2889, 2903, 2913, 2921, 2931, 2939, 2949, 2960, 3011, 3136, 3201, 3222, 3227, 3237, 3302, 3322, 3379, 3439, 3455, 3459, 3472, 3480, 3537, 3548, 3572, 3586, 3593, 3736, 3755, 3782, 3833, 3853, 3859, 3868, 3876, 3894, 3905, 3909, 3934, 3975, 3991, 4002, 4015, 4045, 4050, 4069, 4077, 4115, 4131, 4137, 4205, 4218, 4284, 4303, 4318, 4344, 4349, 4360, 4397, 4401, 4425, 4448], 'leading': [454, 735], 'cause': [455, 737, 887], 'death': [457, 739], 'worldwide,': [458], 'environmental': [460, 675, 716, 804, 874, 1127], 'pollutants': [461, 485, 713, 821, 1048, 1070, 1105], 'are': [462, 504, 1095, 1158], 'increasingly': [463], 'recognized': [464], 'as': [465, 795, 802, 938, 1030, 1381, 1409, 1657, 1687, 2233, 2404, 2566, 2615, 2788, 2848, 2873, 3075, 3413, 3585, 3599, 4221, 4391], 'risk': [466, 489], 'factors': [467, 875], 'atherosclerosis.': [469], 'receptors': [472, 924], '(LXRs)': [473], 'play': [474], 'a': [475, 538, 542, 823, 885, 912, 947, 978, 1225, 1420, 1460, 1487, 1525, 1556, 1608, 1612, 1658, 1842, 1855, 1947, 1960, 2061, 2217, 2591, 2909, 2924, 2945, 2970, 3167, 3274, 3363, 3486, 3543, 3610, 3652, 3705, 3803, 4119, 4158, 4314, 4354, 4370, 4392], 'central': [476, 1014], 'role': [477, 825, 914, 1015], 'atherosclerosis;': [479], 'however,': [480], 'LXR': [481, 980, 1565, 1605, 2102, 2690, 2953, 3589, 3594, 3694], 'activity': [482, 516, 3557, 3738, 3757], 'organic': [484, 1473], 'associated': [487], 'potential': [488, 2616], 'atherosclerosis': [491, 533, 916, 1006, 1020, 1034, 1054, 1076, 1137], 'have': [492, 850, 1027], 'not': [493], 'yet': [494], 'been': [495, 733, 851, 1028], 'characterized.Objectives:This': [496], 'study': [497, 1086, 1157, 1199], 'aimed': [498], 'explore': [500], 'whether': [501, 1092, 1124, 3689, 3781, 3832], 'LXR-antagonistic': [502, 3837], 'chemicals': [503, 673, 1022, 1094, 1128, 1151, 2017, 2118, 2211, 2531, 2621, 2966, 3444, 3784, 3835, 3855], 'present': [505, 842, 1096], 'indoor': [507, 678, 1098, 1194, 1365, 1562, 2106, 2694, 2768, 2802, 2918, 2961, 3690, 3699], 'house': [508, 550, 620, 1304, 1315, 1338, 1910, 3446, 3761], 'dust': [509, 551, 621, 679, 1099, 1195, 1349, 1366, 1398, 1404, 1421, 1563, 1911, 2107, 2695, 2752, 2769, 2803, 2915, 2962, 3447, 3691, 3700, 3762], 'and,': [510], 'if': [511], 'so,': [512], 'characterize': [514], 'relation': [518], 'changes': [520], 'macrophages': [522, 655, 659, 4109, 4261, 4412], 'vitro': [524, 2894], 'indicators': [528], 'vivo': [530, 601], 'mouse': [535, 605, 657, 669, 700, 4107, 4259, 4410], 'model.Methods:We': [536], 'used': [537, 1154, 1196, 1229, 1569, 1656, 1685, 2094, 2203, 2498, 2683, 2936, 3038, 3584, 3598, 3907, 4048, 4128, 4195], 'His-LXRα-pull-down': [539], 'assay': [540, 2973], 'nontarget': [543, 2072, 2790], 'high-resolution': [544], 'mass': [545, 2195, 2628, 2645, 2648, 2673, 2679, 2698, 2740], 'spectrometry': [546, 2680], 'method': [547, 2784, 2883, 2934], 'screen': [549], 'collected': [552, 1201], 'homes': [555, 1269], 'LXRα-': [557], 'LXRβ-antagonist': [559], 'activity.': [560], 'A': [561, 1348, 1535, 1637, 2075, 3734], 'chemical': [562, 820, 2073, 2207, 2791], 'identified': [563, 607, 2965, 3783, 3834], 'manner': [566], 'was': [567, 634, 688, 1087, 1200, 1228, 1354, 1367, 1423, 1457, 1466, 1551, 1588, 1600, 1624, 1655, 1668, 1695, 1746, 1763, 1778, 1823, 1867, 1888, 1905, 1941, 1983, 2012, 2079, 2119, 2164, 2182, 2202, 2212, 2261, 2278, 2319, 2327, 2366, 2372, 2389, 2425, 2453, 2542, 2564, 2682, 2700, 2775, 2785, 2798, 2809, 2871, 2906, 2926, 2935, 3065, 3160, 3410, 3517, 3528, 3558, 3583, 3607, 3649, 3725, 3856, 3865, 3872, 3930, 3977, 3999, 4066, 4084, 4101, 4127, 4142, 4194, 4202, 4215, 4286, 4311, 4346, 4389, 4427, 4456], 'assessed': [568, 2968, 4067, 4085], 'its': [570], 'ability': [571, 626], 'induce': [573, 597, 1053, 1075, 1136], 'cholesterol': [574, 646, 939, 943, 950, 4056], 'efflux': [575, 647, 944, 953, 4057, 4388], 'foam': [577, 650, 933, 955, 984, 1057, 1079, 1131, 4060], 'cell': [578, 651, 891, 934, 985, 1058, 1080, 1132, 3440, 4061, 4355, 4363], 'formation': [579, 652, 665, 895, 935, 986, 1133, 4062], 'RAW264.7': [581, 654, 3935, 3937, 3948, 3967, 4006, 4104], 'macrophages,': [582], 'down-regulate': [584], 'expression': [586, 1800, 1818, 1864, 2989, 3182, 3208, 4214], 'two': [588, 765, 2713], 'LXR-dependent': [589], 'genes,': [590], 'ABCA1': [591], 'ABCG1,': [593], 'finally': [595], 'atherosclerotic': [598, 663, 695, 975, 991], 'lesions': [599, 696], 'using': [602, 1202, 1401, 1631, 1706, 1750, 1959, 2081, 2121, 2461, 2550, 2625, 2974, 3162, 3880, 4068, 4086, 4110, 4204, 4369], 'model.Results:We': [606], 'flame': [609], 'retardants': [610], 'triphenyl': [611, 1167], 'phosphate': [612, 617, 1168, 1175], '(TPHP)': [613], '2-ethylhexyl': [615, 1173], 'diphenyl': [616, 1174], '(EHDPP)': [618, 1176], 'samples': [622, 676, 1249, 1405, 1544, 2563, 2753, 2963], 'demonstrated': [624, 852], 'their': [625, 1187, 2739, 2757], 'antagonize': [628], 'LXRs.': [629], 'The': [630, 836, 1236, 1268, 1364, 1403, 1464, 1478, 1508, 1585, 1799, 1817, 1836, 1863, 2016, 2053, 2109, 2149, 2285, 2360, 2370, 2385, 2396, 2447, 2465, 2555, 2725, 2869, 2987, 2998, 3035, 3063, 3128, 3157, 3180, 3206, 3269, 3335, 3356, 3382, 3406, 3492, 3526, 3588, 3602, 3644, 3668, 3722, 3861, 3870, 3947, 3966, 4188, 4226, 4458], 'potency': [631], 'TPHP': [633, 642, 1505, 2763, 2830, 2843, 2863, 2940, 3821, 3989, 4021, 4301, 4446], 'similar': [635], 'that': [637, 817, 876, 941, 972, 998, 1023, 1047, 1066, 2745], 'LXR-antagonist': [640, 672, 710, 1050, 1072, 1093, 1126], 'SR9238.': [641], 'could': [643], 'also': [644], 'inhibit': [645], 'promote': [649, 691, 1130], 'peritoneal': [658, 4108, 4260, 4411], 'significantly': [661], 'promoted': [662, 988], 'lesion': [664], 'model.Conclusions:We': [670], 'found': [671], 'homes.': [682, 1218], 'One': [683], 'chemicals,': [686], 'TPHP,': [687, 2728, 3792], 'able': [689], 'development': [693], 'model.': [701], 'These': [702, 1060, 2620], 'results': [703], 'highlight': [704], 'need': [706], 'assess': [708], 'activities': [711, 1051, 1073, 2958], 'future': [715], 'management': [717], 'programs.': [718], 'https://doi.org/10.1289/EHP5039IntroductionThe': [719], 'incidence': [720], '(CVD)': [724], 'increased': [726, 2243, 2255], 'many': [728], 'countries,': [729], 'CVD': [731, 745, 782, 807, 830, 849], 'underlying': [736], 'worldwide': [740], 'since': [741], '2000': [742], '(WHO': [743], '2018).': [744], 'contributed': [746], 'one': [748], 'every': [750, 767], 'three': [751, 2854, 3916], 'deaths': [752, 769], 'United': [755], 'States': [756], '2008': [758], '(Roger': [759], 'et': [760, 775, 862, 881, 962, 966, 994, 1008, 1036, 1040, 1111, 1115, 1119, 1413, 2900, 3417], 'al.': [761, 776, 863, 882, 963, 967, 995, 1009, 1037, 1041, 1112, 1116, 1120, 1414, 2901, 3418], '2012)': [762], 'five': [768, 3712], '2014': [773], '(Chen': [774], '2017).': [777], 'More': [778], 'than': [779, 831, 2928], '80%': [780], 'can': [783, 900, 1024, 1129], 'be': [784, 3634, 3677], 'attributed': [785], 'modifiable': [787], 'nongenetic': [789], 'factors,': [790], 'lifestyle': [792], 'choices': [793], 'such': [794], 'smoking,': [796], 'diet,': [797], 'exercise': [799], 'were': [800, 1177, 1239, 1250, 1276, 1394, 1406, 1476, 1481, 1513, 1574, 1686, 1732, 1806, 1839, 1965, 2023, 2055, 2139, 2231, 2297, 2342, 2351, 2402, 2415, 2438, 2457, 2471, 2497, 2613, 2622, 2633, 2720, 2735, 2746, 2823, 2833, 2846, 2967, 2994, 3024, 3039, 3140, 3234, 3246, 3263, 3271, 3304, 3324, 3338, 3345, 3359, 3385, 3424, 3452, 3462, 3476, 3495, 3540, 3597, 3621, 3631, 3663, 3674, 3702, 3716, 3796, 3800, 3824, 3891, 3911, 3939, 3950, 3969, 4008, 4017, 4047, 4229, 4262, 4320, 4351, 4366, 4413], 'considered': [801, 2503, 2614], 'major': [803, 886], 'influences': [805], 'on': [806, 848, 1183, 1242, 1436, 1780, 2038, 2545, 2642, 2676, 2892, 3387, 3875, 4076], '(Bhatnagar': [808, 834, 858], '2006).': [809], 'Recent': [810, 969], 'disparate': [811], 'lines': [812], 'evidences': [814], 'together': [815], 'indicate': [816], 'exposure': [818, 1068, 1108], 'plays': [822], 'larger': [824], 'etiology': [828], 'previously': [832, 1411, 2898, 3415], 'thought': [833], '2004).': [835, 864], 'adverse': [837], 'effects': [838], 'fine': [840], 'particles': [841], 'ambient': [844], 'air': [845], 'metal': [847], 'epidemiological': [854], 'animal': [856, 1141, 1389], 'studies': [857, 970], '2004,': [859], '2006;': [860, 964], 'Brook': [861], 'However,': [865], 'significant': [866], 'gaps': [867], 'remain': [868], 'our': [870], 'understanding': [871], 'affect': [877], 'health': [879], '(Bergman': [880], '2013).Atherosclerosis': [883], 'is': [884, 1045], 'CVD.': [889], 'Foam': [890], '(i.e.,': [892], 'cholesterol-laden': [893], 'macrophages)': [894], 'within': [896], 'artery': [898], 'wall': [899], 'facilitate': [901], 'adventitia': [902], 'angiogenesis': [903], 'buildup': [906], 'necrotic': [908], 'pools,': [909], 'thereby': [910], 'playing': [911], 'key': [913], 'pathogenesis': [917], '(Tontonoz': [918], 'Mangelsdorf': [920, 1646], '2003).': [921, 1042], '(LXRs,': [925], 'including': [926, 1259], 'LXRα': [928, 1622, 1981, 2021, 2097, 2114, 2124, 3003, 3045, 3077, 3130, 3638, 3681, 3746, 3773, 3845], 'LXRβ': [930, 3007, 3051, 3080, 3133], 'subtypes)': [931], 'regulate': [932, 942], 'functioning': [937], 'sensors': [940], 'achieve': [946], 'balance': [948], 'between': [949, 1222, 2532, 2811], 'influx': [951], 'cells': [956, 1771, 1812, 3233, 3245, 3262, 3270, 3303, 3323, 3337, 3358, 3384, 3423, 3494, 3890, 3906, 3938, 3949, 3968, 4007, 4016, 4046, 4105, 4257, 4319, 4350, 4408], '(Glass': [957], 'Witztum': [959], '2001;': [960], 'Pennings': [961], 'Yu': [965], '2013).': [968], 'showed': [971], 'treatment': [973], 'mice': [976, 1004], 'synthetic': [979, 3388], 'agonist': [981, 3590], '(GW3965)': [982], 'inhibited': [983], 'regression': [989, 2817, 2946], 'plaques': [992], '(Joseph': [993, 1035], '2002)': [996], 'macrophage-specific': [999], 'deletion': [1000], 'LXRs': [1002, 1018, 1026, 2976, 4003], 'enhanced': [1005], '(Tangirala': [1007], '2002).': [1010], 'Due': [1011], 'played': [1016], 'pathogenesis,': [1021], 'activate': [1025], 'designed': [1029, 1088, 3040, 4230], 'drugs': [1031], 'treat': [1033], '2002;': [1038], 'Terasaka': [1039], 'Thus,': [1043], 'it': [1044], 'possible': [1046], 'may': [1052], 'promoting': [1056, 1078], 'formation.': [1059], 'findings': [1061], 'led': [1062], 'us': [1063], 'postulate': [1065], 'human': [1067, 1107, 1387, 1621, 2975, 3027], 'would': [1074], 'formation.To': [1081], 'test': [1082], 'hypothesis,': [1084], 'determine': [1090, 2759, 3688, 3780, 3831], 'a)': [1091], '(a': [1100], 'well-known': [1101], 'carrier': [1102], 'various': [1104, 1255, 3713, 3811], 'matrix)': [1109], '(Suzuki': [1110], '2013;': [1113], 'Kassotis': [1114], '2017;': [1117], 'Fang': [1118], '2015),': [1121], 'b)': [1123], 'these': [1125], 'consequently': [1135], 'experimental': [1140], 'model.Materials': [1142], 'MethodsChemicals': [1144], 'ReagentsThe': [1146], 'names': [1147], 'sources': [1149], 'reagents': [1153], 'listed': [1159, 1547], 'Table': [1161, 1247, 1284, 1549, 2733, 3396, 3436, 3504], 'S1.': [1162], 'Dose': [1163], 'solutions': [1164, 3799], 'SR9238,': [1166], '(TPHP),': [1169], 'p-nitrophenol': [1170], '(PNP),': [1171], 'prepared': [1178, 3622, 3664, 3718, 3826], 'dimethyl': [1180], 'sulfoxide': [1181], '(DMSO)': [1182], 'basis': [1185], 'molarity.Indoor': [1188], 'Sample': [1190], 'Collection': [1191], 'ExtractionThe': [1193], 'brooms': [1203], 'main': [1206], 'living': [1207], 'area': [1208, 2571, 2581], '(floor': [1209], 'top': [1212, 2380], 'furniture)': [1214], '29': [1216], 'To': [1219, 2528, 3687, 3779, 3830], 'prevent': [1220, 1582], 'contamination': [1221], 'different': [1223, 3765], 'households,': [1224], 'new': [1226], 'broom': [1227], 'sample': [1231, 1399, 1422, 1558, 1586, 2286, 2294, 2925], 'collection': [1232, 1587], 'each': [1234, 1603, 1937, 2559, 2573, 2583], 'household.': [1235], 'sampling': [1237], 'locations': [1238], 'chosen': [1240], 'based': [1241, 2544, 2641, 2675, 2891, 3874, 4075], 'convenience.': [1243], 'As': [1244, 1379, 2793, 2896], 'shown': [1245], 'S2,': [1248], 'obtained': [1251, 1601, 3892], 'cities': [1253], 'regions': [1256], 'Yiyang,': [1261], 'Zhengzhou,': [1262], 'Fuzhou': [1263], 'Shanghai,': [1264], 'Guangzhou,': [1265], 'Chongqing.': [1267], 'varied': [1270], 'age': [1272, 1312, 1323], 'size': [1274, 1301], 'inhabited': [1277], 'persons': [1279], 'varying': [1281], 'incomes': [1282], '(see': [1283, 1876, 2146, 2184, 2732], 'S2).': [1285], 'For': [1286, 1895, 4001], 'example,': [1287], 'monthly': [1289], 'income': [1290], 'family': [1293], 'ranged': [1294, 1305, 1316, 1327, 1343], '<5,000': [1296], '20,000': [1298], 'RMB,': [1299], '∼20': [1307, 1345], '185': [1309], 'm2,': [1310], '<5': [1318, 1329], '10–30': [1320, 1331], 'y,': [1321, 1332], 'furniture': [1326], 'distance': [1335], 'nearest': [1341], 'road': [1342], '800m.': [1347], 'standard': [1350, 2821, 2857], 'reference': [1351], 'material': [1352], '(SRM2585)': [1353], 'purchased': [1355, 2736, 2995, 3042, 4232], 'National': [1358, 3895], 'Standards': [1361], 'Technology.': [1363], 'collected,': [1368, 4347], 'wrapped': [1369], 'aluminum': [1371], 'foil,': [1372], 'stored': [1374], 'at': [1375, 1448, 1576, 1662, 1755, 1785, 1831, 1919, 1949, 1953, 2047, 2127, 2321, 2329, 2353, 2427, 2473, 2646, 2711, 2805, 2912, 3090, 3114, 3175, 3296, 3326, 3332, 3347, 3353, 3401, 3464, 3482, 3508, 3521, 3550, 3574, 3742, 3764, 3769, 3840, 3914, 3941, 3952, 3990, 4027, 4149, 4183, 4267, 4302, 4379, 4418, 4447], '−20°C': [1376], 'until': [1377], 'extraction.': [1378], 'much': [1380], 'possible,': [1382], 'impurities': [1383], '(clips,': [1384], 'small': [1385], 'stones,': [1386], 'hair,': [1390], 'wood': [1392], 'chips)': [1393], 'removed': [1395, 3477, 3978, 4288, 4428], 'tweezers.': [1402], 'then': [1407, 1441, 1552, 1743, 1791, 1984, 3344, 3360, 3974, 4014, 4155, 4327], 'extracted': [1408, 1424, 2024], 'described': [1410, 2897, 3414], '(Fang': [1412], '2015).': [1415, 3419], 'In': [1416, 1717, 2237, 2306, 2331, 3242], 'brief,': [1417, 1718, 3243], '0.1g': [1418], '5mL': [1426], 'acetone/hexane': [1427, 1455], '(1:1,': [1428], 'vol/vol),': [1429], 'followed': [1430, 1853, 2035], 'shaking': [1432, 2037], '20': [1434, 1975, 3511], 'min': [1435, 2044, 2282, 3331, 3352, 4153], 'orbital': [1438, 2040], 'shaker': [1439, 1948, 2041], 'sonicating': [1442], '15': [1444, 1758, 2043, 3093, 3097, 3117, 3121, 3317], 'min.': [1445, 2052, 2266, 3300, 3525, 4187], 'After': [1446, 1660, 1753, 1924, 1955, 3319, 3438, 3506, 4313], 'centrifugation': [1447], '4,000': [1449, 2048], 'rpm': [1450, 1952, 2049, 3328, 3349], '10': [1452, 2444, 3286, 3368], 'min,': [1453, 1666, 1759, 1784, 2239, 2251, 2477, 3085, 3109, 3512], 'extract': [1456, 1912, 2644, 3250, 3763], 'transferred': [1458, 1792], 'clean': [1461], 'glass': [1462, 1917], 'bottle.': [1463], 'residue': [1465], 'subjected': [1467], 'extraction': [1469, 1572], 'twice,': [1470], 'solvent': [1474], 'extracts': [1475, 1480, 1510, 2054, 2804, 3448, 3692, 3701], 'combined.': [1477], '7.5-mL': [1479], 'evaporated': [1482, 1514], 'near': [1484, 1516, 2058], 'dryness': [1485, 1517, 2059], 'under': [1486, 2060], 'gentle': [1488, 2062], 'stream': [1489, 2063], 'high': [1491, 2677], 'purity': [1492, 4135], 'nitrogen': [1493, 2066], 'reconstituted': [1495, 1519, 2068], '7.5mL': [1497, 1512], 'methanol': [1498], '(MeOH)': [1499], 'determining': [1501, 3479], 'concentrations': [1503, 2761, 3618, 3660, 3714, 3766, 3812, 3992], 'EHDPP.': [1507], 'residual': [1509, 3493], '200μL': [1521, 3498], 'DMSO': [1522, 1528, 1540, 3581, 3863, 3985, 4034, 4041, 4297, 4442], 'form': [1524], '500-mg': [1526], 'dust/mL': [1527], 'solution': [1529, 1541, 1737, 3279, 3365, 3604, 3646], 'yeast': [1532, 2971, 2988, 3181, 3207, 3244, 3249, 3261, 3407, 3422], 'two-hybrid': [1533, 2972, 3408], 'assay.': [1534], '10-μL': [1536], 'aliquot': [1537], '(Samples': [1545], '1–11;': [1546], 'S2)': [1550], 'composited': [1553], 'create': [1555], 'mixture': [1557, 1745, 1762, 1777, 1940, 4159], 'screening': [1560], 'ligands.': [1566], 'Glass': [1567], 'tubes': [1568], 'during': [1570], 'process': [1573], 'pretreated': [1575], '500°C': [1577], '6': [1579], 'h': [1580, 1945, 3258, 3468, 4012], 'background': [1583], 'contaminations.': [1584], 'approved': [1589], 'ethics': [1592], 'committee': [1593], 'informed': [1598], 'consent': [1599], 'homeowner.Screening': [1604], 'Ligands': [1606], 'Pull-Down': [1609], 'Assay': [1610, 4074], 'Nontarget': [1613], 'Chemical': [1614], 'AnalysisIn': [1615], 'pull-down': [1617, 1897], 'assay,': [1618, 1898, 4058], 'full-length': [1620], 'gene': [1623, 4213], 'amplified': [1625, 1691, 1730, 3025, 3129], 'polymerase': [1627, 1636, 3071], 'chain': [1628], 'reaction': [1629, 1761, 3159, 3527], '(PCR)': [1630], 'KOD': [1632], 'FX': [1633], 'Neo': [1634], 'DNA': [1635, 1693, 3070, 3164, 3168], 'plasmid': [1638, 1724, 3209], 'vector': [1639, 1702], 'pCMX-hLXRα,': [1640], 'kindly': [1641], 'provided': [1642], 'Dr.': [1644], 'D.': [1645], 'Texas': [1651], 'Southwestern': [1652], 'template.': [1659], 'preincubation': [1661], '94°C': [1663], '2': [1665, 1944, 2474, 2982, 3020], 'PCR': [1667, 4191], 'performed': [1669, 2013, 2080, 2543, 3066, 3161, 4203], '40': [1671], 'cycles': [1672, 3087, 3111], '98°C': [1674], '(10': [1675], 's),': [1676, 1679], '58°C': [1677, 3119], '(30': [1678], '72°C': [1681, 3100, 3124], '(60': [1682], 's).': [1683], 'Primers': [1684], 'follows:forward': [1688], '5′-GCTCGGTACCCTCGAAATGTCCTTGTGGCTGGG-3′reverse': [1689], '5′-ATTCGGATCCCTCGATCATTCGTGCACATCCCAG-3′.The': [1690], 'circular': [1692], '(cDNA)': [1694], 'subcloned': [1696, 3141], 'into': [1697, 1765, 1808, 3142, 3542], 'pCold-trigger': [1699], 'factor': [1700, 2981, 3019], '(TF)': [1701], 'predigested': [1703, 1723], 'EcoRI': [1705], 'In-Fusion': [1708], 'HD': [1709, 1739], 'Cloning': [1710, 1740], 'Kit': [1711, 4192], 'according': [1712, 4113], 'manufacturer’s': [1715, 4078, 4116], 'instructions.': [1716, 4117], '50': [1720], 'ng': [1721, 1728], '100': [1727, 2354, 2814, 3635, 3743, 3770, 4031], 'cDNA': [1731], 'mixed': [1733, 4143], '2μL': [1735], 'premix': [1736], '(In-Fusion': [1738], 'Kit),': [1741], 'adjusted': [1747], '10μL': [1749], 'double-distilled': [1751], 'water.': [1752], 'incubation': [1754, 3507], '50°C': [1756], 'transformed': [1764, 3235, 3421], 'Escherichia': [1766], 'coil': [1767], '(E.': [1768], 'coli)': [1769], 'DH5α-competent': [1770], 'heat': [1773, 1814, 3313, 3320], 'shock': [1774, 1815, 3314], 'transformation': [1775], '(the': [1776], 'incubated': [1779, 1914, 1942, 3295, 3463, 3940, 4328], 'ice': [1781, 1794], '30': [1783, 3299, 3524], '42°C': [1786, 4184], '90': [1788], 's,': [1789, 3094, 3098, 3118, 3122], 'another': [1796], '3': [1797, 2265, 2410, 3330, 3351], 'min).': [1798, 3318], 'plasmids': [1801, 3183], 'pCold-His-TF-LXRα': [1803], 'or': [1804, 1821, 3132, 3445, 3696, 3787, 3988, 4030, 4038, 4258, 4300, 4335, 4409, 4445], 'pCold-His-TF': [1805], 'transfected': [1807, 3305, 3383], 'E.': [1809], 'coli': [1810], 'BL21': [1811], 'transformation.': [1816], 'His-TF': [1820, 1903, 2087], 'His-TF-LXRα': [1822, 1866, 2091, 2162, 2534, 2577, 2602], 'induced': [1824, 3739], '0.4': [1826], 'mM': [1827, 1972, 1976, 1997, 2000, 2004, 3287, 3290, 3369, 3372], 'isopropyl': [1828], 'β-d': [1829], 'thiogalactoside': [1830], '20°C': [1832], '18': [1834, 3257], 'h.': [1835, 1923, 3179, 4282, 4342], 'recombinant': [1837, 2113], 'proteins': [1838], 'purified': [1840, 2096], 'nickel-affinity': [1843], 'column': [1844, 1849, 2219, 2291], '(Ni2+-charged': [1845], 'HiTrap': [1846], 'chelating': [1847], 'high-performance': [1848, 2191], 'GE': [1851], 'Healthcare),': [1852], 'Hitrap': [1856], 'desalting': [1857], '(GE': [1858, 4123], 'Healthcare)': [1859], 'remove': [1861], 'imidazole.': [1862], 'detected': [1868], 'sodium': [1870, 3533], 'dodecyl': [1871], 'sulfate-polyacrylamide': [1872], 'gel': [1873, 1887], 'electrophoresis': [1874], '(SDS-PAGE)': [1875], 'Figure': [1877, 2147, 2185], 'S1A)': [1878], '4%': [1880], 'stacking': [1881], '15%': [1883], 'resolving,': [1884], 'stained': [1889], 'Coomassie®': [1891], 'blue': [1892], '(Imperial': [1893], 'Chemical).': [1894], '20μMHis-TF-LXRα': [1899], '(n=6)': [1900, 1904], '20μM': [1902], 'spiked': [1906, 2158, 2176], '5μL': [1908], '2-mL': [1916], 'tubes)': [1918], '4°C': [1920], '1': [1922, 3178, 3289, 3371], 'adding': [1925, 2026, 3531], '100μL': [1926, 3532], 'His-select': [1928, 1988], 'nickel': [1929, 1989], 'magnetic': [1930, 1961, 1990], 'agarose': [1931, 1991], 'beads': [1932, 1992], '(Beaver': [1933], 'Science)': [1935, 4126], 'tube,': [1938], 'approximately': [1950], '170': [1951], '4°C.': [1954], 'removing': [1956], 'supernatant': [1958], 'separator,': [1962], 'residues': [1964, 3198, 3224], 'washed': [1966, 4321], 'twice': [1967], '1mL': [1969, 1994], 'buffer': [1970, 1995, 3500, 4181, 4365], '(20': [1971, 1996], 'Tris': [1973], 'NaCl;': [1977], 'pH': [1978, 2006, 3292, 3374], '8.0),': [1979], 'protein': [1982, 2009, 2022, 2088, 2098, 3186, 3212], 'eluted': [1985], 'Tris,': [1998], '500': [1999], 'NaCl,': [2001], '250': [2003], 'imidazole;': [2005], '8.0).': [2007], 'This': [2008], 'elution': [2010], 'step': [2011], 'triplicate.': [2015], 'bound': [2018], 'ethyl': [2027], 'acetate': [2028, 3239], '(7mL)': [2029], 'formic': [2031], 'acid': [2032], '(FA;': [2033], '60μL),': [2034], 'centrifuging': [2046], '5': [2051, 2651, 2703, 2806, 3084, 3108, 4152], 'concentrated': [2056], 'high-purity': [2065], 'MeOH': [2070, 2228], 'analysis.': [2074, 2208, 2501, 2792, 4198], 'negative': [2076, 2417, 2487, 2515], 'control': [2077, 2180, 2340, 2536, 2587, 2611], 'experiment': [2078, 2506, 3409, 3910], 'same': [2083, 2787], 'protocol': [2084], 'but': [2085], 'instead': [2089], 'protein.': [2092], 'We': [2093], 'freshly': [2095], 'pull': [2100, 2116], 'down': [2101, 2117, 2154, 2172], 'ligands': [2103, 2617, 2691], 'extracts.': [2108], 'efficiency': [2110], 'confirmed': [2120], 'positive': [2123, 2419, 2495, 2526, 2778, 3600], 'ligand': [2125], 'TO901317': [2126, 2138, 2155, 2173, 3591, 3606, 3741, 3768, 3839, 4026], '0.25-,': [2128], '2.5-,': [2129], '25-,': [2130], '250-μg/L': [2132], 'concentrations,': [2133], 'recoveries': [2136], '100%±3%,': [2140], '85%±5%,': [2141], '80%±0.7%,': [2142], '92%±4%,': [2144], 'respectively': [2145], 'S1B).': [2148], 'average': [2150, 2168, 2850], 'percentage': [2151, 2169, 4393], 'pulled': [2153, 2171], 'concentration': [2159, 2177, 2878, 2886, 2905, 2942, 3628, 3671, 3864, 4304, 4449], 'group': [2163, 2181, 2578, 2603, 2612], '89%,': [2165], '10%': [2183, 3925, 4275, 4293, 4433], 'S1C).A': [2186], 'Dionex': [2187], 'UltiMate': [2188], '3000': [2189], 'Ultra': [2190], 'liquid': [2192], 'chromatography–quaternary': [2193], '(UHPLC-Q)-Exactive™': [2194], 'spectrometer': [2196], '(MS)': [2197], 'system': [2198, 4209], '(Thermo': [2199, 3072, 3489], 'Fisher': [2200, 3073, 3490], 'Scientific)': [2201, 3074], 'nontargeted': [2206], 'Separation': [2209], 'achieved': [2213], 'use': [2215, 2637], 'C18': [2218], '(1.7μm,': [2220], '2.1mm×100mm;': [2221], 'Waters).': [2222], 'Milli-Q®': [2223], 'water': [2224], '(A': [2225], 'phase)': [2226, 2230], '(B': [2229], 'employed': [2232, 3931], 'mobile': [2235], 'phases.': [2236], '0–3': [2238], 'B': [2241, 2253, 2269, 3753], 'phase': [2242, 2254, 2270], '5%': [2245, 3944], '60%.': [2247], 'Then': [2248, 2663, 3301, 3471, 3555, 4044, 4118, 4343, 4424], '3–13': [2250], '60%': [2257], '100%,': [2259], 'held': [2262, 2279], 'static': [2263], 'Finally': [2267], 'fell': [2271], 'back': [2272], 'initial': [2275, 2466], 'condition,': [2276], 'which': [2277, 2670], '4': [2281, 3467, 4341], 'equilibration.': [2284], 'injection': [2287, 2348], 'volume,': [2288], 'flow': [2289, 2433, 2437], 'rate,': [2290], 'temperature,': [2292], 'compartment': [2295], 'temperature': [2296, 2424], 'set': [2298, 2320, 2328, 2352, 2367, 2373, 2390, 2403, 2439, 2472, 2701, 2847], '5μL,': [2300], '0.30mL/min,': [2301], '40°C,': [2302], '5°C,': [2304], 'respectively.': [2305, 2359, 2446, 3156, 3580], 'mode': [2308, 2401, 2488, 2496, 2516], 'full': [2310, 2316, 2333], 'scan': [2311, 2317, 2334], 'MS/data-dependent': [2312], '(dd)': [2313], 'MS2,': [2314], 'resolution': [2318, 2326, 2678], '70,000,': [2322], 'ddMS2': [2325], '17,500.': [2330], 'ddMS2,': [2336], 'automatic': [2338], 'gain': [2339], 'values': [2341, 2350, 3630, 3673], '3×106': [2343], '5×104,': [2345], 'maximum': [2347, 2914], 'time': [2349], 'ms': [2355], '80': [2357], 'ms,': [2358], 'isolation': [2361], 'window': [2362], 'precursor': [2364], 'ions': [2365, 2715], '1.0m/z.': [2369], 'TopN': [2371], '5,': [2375, 4028], 'where': [2376, 3566, 3733], 'N': [2377], 'represents': [2378, 3735, 3754], 'most': [2381], 'abundant': [2382], 'product': [2383, 2714], 'ions.': [2384], 'step-normalized': [2386], 'collision': [2387], 'energy': [2388], '10,': [2392, 4029], '30,': [2393], '50.': [2395], 'parameters': [2397], 'electrospray': [2399], 'ionization': [2400, 2779], 'follows:': [2405, 3076], 'spray': [2407], 'voltages': [2408], 'kV': [2411, 2414], '3.5': [2413], 'modes,': [2420], 'respectively;': [2421], 'capillary': [2423], 'maintained': [2426], '320°C;': [2428], 'sheath': [2431], 'gas': [2432, 2436], 'auxiliary': [2435], '35': [2441, 3086, 3110], 'Arb': [2442], 'Arb,': [2445], 'S-lens': [2448], 'radio': [2449], 'frequency': [2450], '(rf)': [2451], 'level': [2452], '50.The': [2454], 'data': [2455], 'sets': [2456], 'deconvoluted': [2458], 'aligned': [2460, 2547], 'Progenesis®': [2462, 2639], 'QI': [2463, 2640], '(Waters).': [2464], 'final': [2468, 3862], 'retention': [2469, 2630], 'times': [2470, 2855], '16.2': [2476], 'respectively,': [2478, 4368], 'peaks': [2480, 2706], '5,000': [2482], 'minimum': [2483, 2491], 'intensity': [2484, 2492], '10,000': [2490], 'further': [2500, 2634, 2723, 3717, 3825, 4315], 'Adducts': [2502], 'included': [2507], '[M-H2O-H]−,': [2508], '[M-H]−,': [2509], '[M+Cl]−,': [2510], '[M+FA-H]−': [2512], '[M+H-H2O]+,': [2518], '[M+H]+,': [2519], '[M+NH4]+,': [2520], '[M+Na]+,': [2521], '[M+K]+': [2523], 'mode.': [2527], 'differentiate': [2529], 'groups,': [2537], 'principal': [2538], 'component': [2539], 'analysis': [2540], '(PCA)': [2541], 'peak': [2548, 2574, 2584], 'list': [2549], 'SIMCA-P+': [2551], '(version': [2552, 3883], '12.0;': [2553], 'Umetrics).': [2554], 'fold': [2556, 2592, 2607], 'change': [2557, 2593, 2608], 'feature': [2560], 'matched': [2561, 2716], 'across': [2562], 'calculated': [2565, 2635, 2872, 2907, 3559, 3726, 3873], 'ratio': [2568, 2875], 'group.': [2588], 'Peaks': [2589], '>3': [2595], '(p<0.05': [2596], 'Student’s': [2598], 't-test)': [2599], 'compared': [2604, 2747], 'LXRα.': [2619], 'manually': [2623], 'checked': [2624], 'formula': [2626], 'exact': [2627], 'time.': [2631], 'Formulas': [2632], 'error': [2649], 'ppm,': [2652, 2704], 'element': [2653], 'numbers': [2654], 'C50H200N10O10P5S5Cl10Br10F10,': [2656], 'isotopic': [2659], 'difference': [2660], '<10%.': [2662], 'database': [2665, 2719], 'mzCloud': [2667], '(': [2668], 'https://www.mzcloud.org/),': [2669], 'provides': [2671], 'accurate': [2672], 'spectra': [2674, 2709, 2741], '(HRMS),': [2681], 'identify': [2685], 'structures': [2687], 'samples,': [2696, 2837], 'tolerance': [2699], 'MS/MS': [2708], 'containing': [2710, 3924, 4160, 4274, 4292, 4332, 4432], 'least': [2712, 3915], 'selected': [2721, 3386], 'evaluation.': [2724], 'standards': [2726, 3790], 'EHDPP,': [2729, 3793], 'PNP': [2731, 3795, 3816], 'S1)': [2734], 'obtaining': [2738], 'chromatograms': [2744], 'those': [2749], 'ultimately': [2755], 'confirm': [2756], 'structures.To': [2758], 'EHDPP': [2765, 2832, 2845], 'extracts,': [2770], 'UHPLC-Q': [2772], 'Exactive™': [2773], 'MS': [2774], 'operated': [2776], 'mode,': [2780], 'instrumental': [2783, 2882], 'internal': [2795], 'standard,': [2796], 'TPHP-d15': [2797], 'added': [2799, 3453, 3518, 3541, 3857], 'ng/mL.': [2807], 'Linearity': [2808], 'valid': [2810], '0.1': [2812], 'ng/mL,': [2815], 'coefficients': [2818], '7-point': [2820], 'curves': [2822, 3879], 'always': [2824], '>0.99.': [2825], 'Because': [2826], 'low': [2827], 'levels': [2828], 'detectable': [2834], 'blank': [2836, 2851], 'limit': [2839], 'detection': [2841, 4201, 4208], 'signal': [2852], 'plus': [2853], 'deviation': [2858], '(SD)': [2859, 3390], '(0.05': [2860], 'ng/mL': [2861, 2866], '0.01': [2865], 'EHDPP).': [2868], 'contribution': [2870], 'determined': [2879, 3632, 3675], 'equivalent': [2887, 2904, 2941], 'inhibition': [2890, 2922, 3723], 'bioassay.': [2895], '(Villeneuve': [2899], '2000),': [2902], 'single-point': [2910], 'estimation': [2911, 2933], 'dose': [2916], '(500μg': [2917], 'dust/mL)': [2919], 'when': [2920], 'less': [2927], '20%,': [2929], 'otherwise': [2930], 'multiple-point': [2932], 'derivate': [2938], 'fitting': [2944], 'model': [2947], 'dose–response': [2950], 'relationship.Assessment': [2951], 'ActivityThe': [2954], 'LXR-agonistic': [2955, 3786], '-antagonistic': [2957, 3788], 'coactivator': [2978], 'transcription': [2979, 3033, 4053], 'intermediary': [2980, 3018], 'Saccharomyces': [2984], 'cerevisiae': [2985], 'Y187.': [2986], 'plasmids,': [2990], 'pGBT9': [2991, 3143], 'pGAD424,': [2993], 'Clontech/Takara-Bio.': [2997], 'ligand-binding': [2999], 'domains': [3000, 3014], '(LBDs)': [3001], '(residues': [3004, 3008, 3022], '205–447)': [3005], '219–460)': [3009], 'receptor': [3012], 'interaction': [3013], '(RIDs)': [3015], 'transcriptional': [3017], '(TIF2)': [3021], '483–1,090)': [3023], 'total': [3028, 4402], 'RNA': [3029, 4100, 4140], '(Clontech/Takara-Bio)': [3030], 'reverse': [3032, 3049, 3055, 3061, 4052, 4166], '(RT)-PCR.': [3034], 'following': [3036, 4227], 'primers': [3037, 4228], 'Sigma-Aldrich:': [3044], 'LBD:': [3046, 3052, 3081], 'forward': [3047, 3053, 3059], '5ʹ-CGGAGGAGTGTGTCCTGTCAGA-3′,': [3048], '5′-TCATTCGTGACGCCCAGATCTC-3′;': [3050], '5′-AGGGAGCAGGCTCCTTTCTGAA-3′,': [3054], '5′-TCACTCGTGGACGCCCAGATCTC-3′;': [3056], 'TIF2': [3057, 3104, 3137], 'RID:': [3058, 3105], '5′-TCCGAATCCCACCCAGTCAG-3′,': [3060], '5′-TAAGGCTCTATCAATCTCCTCCAG-3′.': [3062], 'RT-PCR': [3064, 4197], 'AmpliTaq': [3068], 'Gold®': [3069], 'LBD': [3078, 3131, 3134], '95°C': [3082, 3091, 3106, 3115], 'denaturation': [3089, 3113], '60°C': [3095], '60': [3102, 4186], 's;': [3103], '120': [3126], 's.': [3127], 'RID': [3138, 3218], 'fragments': [3139], 'digested': [3144, 3151], 'SmaI-BamHI': [3146], '(Takala': [3147], 'Bio)': [3148, 3172], 'pGAD424': [3150], 'EcoRI-BamHI': [3153], '(Takara': [3154, 3171], 'Bio),': [3155], 'ligation': [3158, 3169], 'T4': [3163], 'ligase': [3165], 'kit': [3170], 'incubating': [3174], '16°C': [3176], 'fusion': [3185, 3211], 'GAL4': [3188, 3202, 3214, 3228], 'DNA-binding': [3189], 'domain': [3190, 3216], '(DBD)—LXR-LBD': [3191], '(pGBT9-LXRα': [3192], 'pGBT9-LXRβ)': [3194, 3309], 'consisted': [3195, 3220], 'LXR-LBD': [3197], 'coupled': [3199, 3225], 'DBD': [3203], 'pGBT9.': [3205], 'activation': [3215], '(AD)–TIF2': [3217], '(pGAD-TIF2)': [3219], 'TIF2-RID': [3223], 'AD': [3229], 'pGAD424.': [3231], 'Yeast': [3232], 'lithium': [3238], '(LiAc)': [3240], 'method.': [3241], 'precultured': [3247], 'peptone': [3251], 'dextrose': [3252], '(YPDA)': [3253], 'medium': [3254, 3392, 3432, 3457, 3923, 3976, 4285, 4331, 4345, 4361, 4398, 4426], '(Clontech/Takara-Bio).': [3255], 'At': [3256], 'after': [3259, 3758], 'preculture,': [3260], 'grown': [3264, 3972, 4422], 'optical': [3266], 'density': [3267], '(OD)595=0.4–0.6.': [3268], 'resuspended': [3272, 3339, 3361], 'polyethylene': [3275], 'glycol': [3276], '(PEG)': [3277], 'LiAc': [3278, 3364], '(0.1M': [3280, 3366], 'LiAc,': [3281, 3367], '40%': [3282], 'wt/vol': [3283], 'PEG': [3284], '4000,': [3285], 'Tris-HCl,': [3288, 3370], 'EDTA;': [3291, 3373], '7.5)': [3293, 3375], '30°C': [3297, 3402, 3465, 3509, 3522], 'pGBT9-LXRα': [3307], '(or': [3308], 'pGAD-TIF2': [3311], '(42°C': [3315], 'shock,': [3321], 'centrifuged': [3325, 3336, 3346, 3357], '3,000': [3327, 3348], 'room': [3333, 3354], 'temperature.': [3334, 3355], 'distilled': [3341], 'water,': [3342], 'plated': [3377, 3951, 3970, 4263, 4414], 'onto': [3378], 'agar': [3380, 3400], 'plate.': [3381], 'defined': [3389], 'minimal': [3391], '(for': [3393, 3433, 3501], 'details,': [3394, 3434, 3502], 'see': [3395, 3435, 3503], 'S3)': [3397], 'solidified': [3398], '2–3': [3404], 'd.': [3405], 'carried': [3411], 'out': [3412], '(Zhang': [3416], 'Briefly,': [3420], 'cultured': [3425, 3912, 4271], '(∼15h,': [3426], '30°C,': [3427], 'shaking)': [3429], 'SD': [3431, 3456], 'S3).': [3437, 3505], 'suspension': [3441], '(50μL)': [3442], '(2.5μL,': [3449], 'DMSO)': [3451], '(200μL),': [3458], 'culture': [3460, 3473, 3933], 'mixtures': [3461, 3474, 3538], 'shaking.': [3470], '(150μL)': [3475, 3539], 'absorbance': [3481, 3549, 3573], '595': [3483], 'nm': [3484], 'microplate': [3487, 3545, 4092], 'reader': [3488, 4093], 'Scientific).': [3491], 'lysed': [3496, 4352], 'Z': [3499], '40μL': [3513], '2-nitrophenyl-b-d-galactoside': [3515], '(4mg/mL)': [3516], 'reacted': [3520], 'terminated': [3529], 'carbonate': [3534], '(1M).': [3535], 'Finally,': [3536], '96-well': [3544, 4265], 'detecting': [3547], '415': [3551], '570': [3553, 3578], 'nm.': [3554], 'β-galactosidase': [3556, 3563, 3737, 3756], 'Equation': [3561, 3728], '1:': [3562], 'activity=(OD415−1.75×OD570)/(OD595)': [3564], '[1]': [3565], 'OD595,': [3567], 'OD415,': [3568], 'OD570': [3570], 'represent': [3571], '595,': [3575], '415,': [3576], 'nm,': [3579], '(1%)': [3582], 'control.': [3587], 'antagonist': [3595], 'SR9238': [3596, 3648], 'controls.': [3601], 'stock': [3603, 3645], 'diluted': [3608, 3650, 3703, 3801, 3854], '3-fold': [3611, 3706], 'serial': [3612, 3654, 3707, 3805], 'dilution': [3613, 3655, 3708, 3806], 'DMSO,': [3615, 3657, 3710, 3808], '(0.05–3,000': [3619], 'nM)': [3620, 3662], '(n=3': [3623, 3665, 3719, 3827, 3996, 4035, 4080, 4308, 4453], 'per': [3624, 3666, 3720, 3828, 3997, 4036, 4081, 4309, 4454], 'group).': [3625, 3667, 3721, 3829, 4082], 'Half-maximal': [3626], 'effective': [3627], '(EC50)': [3629], 'nM': [3636, 3641, 3679, 3684, 3744, 3749, 3771, 3776, 3814, 3819, 3843, 3848, 3995, 4032, 4307, 4452], '220': [3640, 3748, 3775, 3847], 'LXRβ.': [3643, 3686, 3778], '2-fold': [3653, 3804], '(24.4–25,000': [3661, 3813], 'half-maximal': [3669], 'inhibitory': [3670], '(IC50)': [3672], '824.7': [3678], '446.4': [3683], 'possessed': [3693, 3785, 3836], 'agonistic': [3695], 'antagonistic': [3697], 'activity,': [3698, 3789, 3838], '(6–500μg/mL)': [3715], '(%)': [3724], '2:': [3729], 'Inhibition': [3730], '%=([A−B]A)×100': [3731], '[2]': [3732], 'LXRβ,': [3751], 'co-exposing': [3759], 'tested.': [3797], 'Stock': [3798], '48.8–50,000': [3818], 'EHDPP)': [3823], 'EC50': [3841], '(100': [3842], 'LXRβ)': [3850], 'along': [3851], 'medium.': [3860, 3869], '1%': [3866], 'IC50': [3871], 'sigmoidal': [3877], 'dose–effect': [3878], 'Prism': [3881], 'software': [3882], '5;': [3884], 'Graphpad': [3885], 'Inc.).Cell': [3886], 'Cultures': [3887], 'TreatmentsRAW264.7': [3889], 'Infrastructure': [3896], 'Resource': [3900], 'China,': [3903], 'passages.': [3917], 'Dulbecco’s': [3918], 'Modified': [3919], 'Eagle’s': [3920], 'Medium': [3921], '(DMEM)-F12': [3922], 'fetal': [3926], 'bovine': [3927], 'serum': [3928], '(FBS)': [3929], 'cells.': [3936], '37°C': [3942], 'carbon': [3945], 'dioxide.': [3946], '2.5×105': [3953], 'cells/well': [3954, 3958, 3963, 4269, 4420], '(6-well': [3955], 'plates),': [3956, 3960], '6.0×104': [3957, 4419], '(24-well': [3959], '104': [3962, 4268], '(96-well': [3964], 'plates).': [3965], 'overnight;': [3973], 'fresh': [3980, 4290, 4430], 'DMEM-F12': [3981, 4273, 4291, 4431], 'contained': [3982], '0.1%': [3984, 4040, 4296, 4441], '(control;': [3986, 4042, 4298, 4443], 'n=3)': [3987, 4024, 4299, 4444], '1–20,000': [3994, 4306, 4451], 'group)': [3998, 4037, 4310, 4455], 'added.': [4000, 4312, 4457], 'reactivated': [4004], 'experiment,': [4005], 'seeded': [4009], '24': [4011, 4281], 'treated': [4018], 'simultaneously': [4019], '(10,000': [4022], 'nM,': [4023], 'n=3).': [4043], 'quantitative': [4051], '(qRT)-PCR,': [4054], 'cellular': [4055], 'experiment.Cell': [4063], 'ViabilityCell': [4064], 'viability': [4065], 'CellTiter-Glo®': [4070], 'Luminescent': [4071], 'Viability': [4073], 'instructions': [4079], 'Luminescence': [4083], 'LB': [4088], '941': [4089], 'TriStar': [4090], 'multimode': [4091], '(Berthold': [4094], 'Technologies).Quantitative': [4095], 'Reverse': [4096], 'Transcription–Polymerase': [4097], 'Chain': [4098], 'ReactionTotal': [4099], 'isolated': [4102], 'TRIzol': [4111], 'reagent': [4112], 'Nanovue': [4120], 'Plus™': [4121], 'spectrophotometer': [4122], 'Healthcare': [4124], 'analyze': [4130], 'concentration,': [4132], 'quality,': [4133], 'RNA.': [4138], 'Total': [4139], '(1μg)': [4141], 'oligo': [4145], 'deoxythymine': [4146], '(dT)': [4147], '(1μL)': [4148], '70°C': [4150], 'combined': [4156], 'Moloney': [4161], 'murine': [4162], 'leukemia': [4163], 'virus': [4164], '(MMLV)': [4165], 'transcriptase': [4167], '(1μL),': [4168], 'deoxy-ribonucleoside': [4169], 'triphosphate': [4170], '(dNTP)': [4171], '(1.25μL),': [4172], 'Recombinant': [4173], 'RNasin®': [4174], 'Ribonuclease': [4175], 'Inhibitor': [4176], '(Promega)': [4177], '(0.65μL),': [4178], 'MMLV': [4180], '(5μL)': [4182], 'SYBR®': [4189], 'Green': [4190], '(TOYOBO)': [4193], 'Real-time': [4199], 'fluorescence': [4200, 4395], 'StepOnePlus™': [4206], 'sequence': [4207], '(Applied': [4210], 'Biosystems).': [4211], 'Relative': [4212], 'evaluated': [4216], '2−ΔΔCt': [4219], 'method,': [4220], 'suggested': [4222], 'Applied': [4224], 'Biosystems.': [4225], 'Sangon': [4234], 'Biotech:actin:': [4235], '5′-CCTGGCACCCAGCACAAT-3′': [4236], '5′-GCCGATCCACACACGGAGTACT-3′': [4238], 'ATP-binding': [4239], 'cassette': [4240, 4247], 'transporter': [4241, 4248], 'A1': [4242], '(ABCA1):': [4243], '5′-CCCAGAGCAAAAAGGGACTC-3′': [4244], '5′-GGTCATCATCACTTTGGTCCTTG-3′ATP-binding': [4246], 'G1': [4249], '(ABCG1):': [4250], '5′-CAAGACCCTTTTGAAAGGGATCTC-3′': [4251], '5′-GCCAGAATATTCATGAGTGTGGAC-3′.Cellular': [4253], 'Cholesterol': [4254, 4387], 'Efflux': [4255], 'AssayRAW264.7': [4256], 'plates': [4266, 4417], 'FBS': [4276, 4294], '1μg/mL22-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-23,24-bisnor-5-cholen-3β-Ol': [4278], '(NBD-cholesterol)': [4279], 'Subsequently,': [4283], 'completely': [4287], '24-h': [4316], 'incubation,': [4317], 'phosphate-buffered': [4323], 'saline': [4324], '(PBS)': [4325], 'serum-free': [4330], 'ApoA-I': [4333], '(20μg/mL)': [4334], 'high-density': [4336], 'lipoprotein': [4337, 4438], '(HDL;': [4338], '50μg/mL)': [4339], 'lysis': [4356, 4364], 'buffer.': [4357], 'NBD-cholesterol': [4358], 'measured,': [4367], 'Tecan': [4371], 'Infinite®': [4372], 'M1000Pro': [4373], 'Microplate': [4374], 'Reader': [4375], '(Tecan': [4376], 'Group': [4377], 'Ltd.)': [4378], '485-nm': [4380], 'excitation': [4381], 'wavelength': [4382], '535-nm': [4384], 'emission': [4385], 'wavelength.': [4386], 'expressed': [4390], 'relative': [4399], 'amount': [4403], 'fluorescence.Foam': [4405], 'FormationRAW264.7': [4407], '24-well': [4416], 'overnight.': [4423], 'FBS,': [4434], '20μg/mL': [4435], 'oxidized': [4436], 'low-density': [4437], '(ox-LDL),': [4439]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2984392772', 'counts_by_year': [{'year': 2024, 'cited_by_count': 10}, {'year': 2023, 'cited_by_count': 21}, {'year': 2022, 'cited_by_count': 18}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 8}], 'updated_date': '2024-12-19T10:17:36.293679', 'created_date': '2019-11-22'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
