Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2981743892', 'doi': 'https://doi.org/10.18632/aging.102249', 'title': 'Long noncoding RNA GAS5 inhibits cell proliferation and fibrosis in diabetic nephropathy by sponging miR-221 and modulating SIRT1 expression', 'display_name': 'Long noncoding RNA GAS5 inhibits cell proliferation and fibrosis in diabetic nephropathy by sponging miR-221 and modulating SIRT1 expression', 'publication_year': 2019, 'publication_date': '2019-10-20', 'ids': {'openalex': 'https://openalex.org/W2981743892', 'doi': 'https://doi.org/10.18632/aging.102249', 'mag': '2981743892', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/31631065', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6834398'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/aging.102249', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210231119', 'display_name': 'Aging', 'issn_l': '1945-4589', 'issn': ['1945-4589'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://doi.org/10.18632/aging.102249', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5103161006', 'display_name': 'Xiaoxu Ge', 'orcid': 'https://orcid.org/0000-0002-2533-9057'}, 'institutions': [{'id': 'https://openalex.org/I4210107879', 'display_name': 'Tongren Hospital', 'ror': 'https://ror.org/01r8rcr36', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210107879']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiaoxu Ge', 'raw_affiliation_strings': ['Department of Endocrinology, Tongren Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Endocrinology, Tongren Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China', 'institution_ids': ['https://openalex.org/I4210107879']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026797857', 'display_name': 'Bojin Xu', 'orcid': 'https://orcid.org/0000-0002-0410-016X'}, 'institutions': [{'id': 'https://openalex.org/I4210107879', 'display_name': 'Tongren Hospital', 'ror': 'https://ror.org/01r8rcr36', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210107879']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Bojin Xu', 'raw_affiliation_strings': ['Department of Endocrinology, Tongren Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Endocrinology, Tongren Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China', 'institution_ids': ['https://openalex.org/I4210107879']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102795238', 'display_name': 'Wenwei Xu', 'orcid': 'https://orcid.org/0000-0002-0951-0950'}, 'institutions': [{'id': 'https://openalex.org/I4210107879', 'display_name': 'Tongren Hospital', 'ror': 'https://ror.org/01r8rcr36', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210107879']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wenwei Xu', 'raw_affiliation_strings': ['Department of Endocrinology, Tongren Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China', 'Department of Geriatrics, Tongren Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Geriatrics, Tongren Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China', 'institution_ids': ['https://openalex.org/I4210107879']}, {'raw_affiliation_string': 'Department of Endocrinology, Tongren Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China', 'institution_ids': ['https://openalex.org/I4210107879']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101754093', 'display_name': 'Lili Xia', 'orcid': 'https://orcid.org/0000-0003-3924-7513'}, 'institutions': [{'id': 'https://openalex.org/I4210107879', 'display_name': 'Tongren Hospital', 'ror': 'https://ror.org/01r8rcr36', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210107879']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Lili Xia', 'raw_affiliation_strings': ['Department of Endocrinology, Tongren Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Endocrinology, Tongren Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China', 'institution_ids': ['https://openalex.org/I4210107879']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083651302', 'display_name': 'Zhongqin Xu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210107879', 'display_name': 'Tongren Hospital', 'ror': 'https://ror.org/01r8rcr36', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210107879']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhongqin Xu', 'raw_affiliation_strings': ['Department of Family Medicine, Tongren Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Family Medicine, Tongren Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China', 'institution_ids': ['https://openalex.org/I4210107879']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045281555', 'display_name': 'Lisha Shen', 'orcid': 'https://orcid.org/0000-0002-1808-6370'}, 'institutions': [{'id': 'https://openalex.org/I4210107879', 'display_name': 'Tongren Hospital', 'ror': 'https://ror.org/01r8rcr36', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210107879']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Lisha Shen', 'raw_affiliation_strings': ['Department of Endocrinology, Tongren Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Endocrinology, Tongren Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China', 'institution_ids': ['https://openalex.org/I4210107879']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101813935', 'display_name': 'Wenfang Peng', 'orcid': 'https://orcid.org/0000-0002-2905-1210'}, 'institutions': [{'id': 'https://openalex.org/I4210107879', 'display_name': 'Tongren Hospital', 'ror': 'https://ror.org/01r8rcr36', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210107879']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wenfang Peng', 'raw_affiliation_strings': ['Department of Endocrinology, Tongren Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Endocrinology, Tongren Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China', 'institution_ids': ['https://openalex.org/I4210107879']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5061272605', 'display_name': 'Shan Huang', 'orcid': 'https://orcid.org/0000-0001-8125-953X'}, 'institutions': [{'id': 'https://openalex.org/I4210107879', 'display_name': 'Tongren Hospital', 'ror': 'https://ror.org/01r8rcr36', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210107879']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Shan Huang', 'raw_affiliation_strings': ['Department of Endocrinology, Tongren Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Endocrinology, Tongren Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China', 'institution_ids': ['https://openalex.org/I4210107879']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 5.498, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 78, 'citation_normalized_percentile': {'value': 0.723491, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '11', 'issue': '20', 'first_page': '8745', 'last_page': '8759'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10515', 'display_name': 'Cancer-related molecular mechanisms research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10515', 'display_name': 'Cancer-related molecular mechanisms research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/gas5', 'display_name': 'GAS5', 'score': 0.91216433}, {'id': 'https://openalex.org/keywords/competing-endogenous-rna', 'display_name': 'Competing Endogenous RNA', 'score': 0.601343}], 'concepts': [{'id': 'https://openalex.org/C2776941990', 'wikidata': 'https://www.wikidata.org/wiki/Q18045451', 'display_name': 'GAS5', 'level': 5, 'score': 0.91216433}, {'id': 'https://openalex.org/C62203573', 'wikidata': 'https://www.wikidata.org/wiki/Q15087973', 'display_name': 'Long non-coding RNA', 'level': 4, 'score': 0.7345762}, {'id': 'https://openalex.org/C127561419', 'wikidata': 'https://www.wikidata.org/wiki/Q224527', 'display_name': 'Downregulation and upregulation', 'level': 3, 'score': 0.68391365}, {'id': 'https://openalex.org/C60365752', 'wikidata': 'https://www.wikidata.org/wiki/Q5156306', 'display_name': 'Competing endogenous RNA', 'level': 5, 'score': 0.601343}, {'id': 'https://openalex.org/C2779922275', 'wikidata': 'https://www.wikidata.org/wiki/Q1129105', 'display_name': 'Diabetic nephropathy', 'level': 3, 'score': 0.5629798}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.5569371}, {'id': 'https://openalex.org/C62112901', 'wikidata': 'https://www.wikidata.org/wiki/Q189159', 'display_name': 'Cell growth', 'level': 2, 'score': 0.49130407}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3988678}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.33272362}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.3303231}, {'id': 'https://openalex.org/C2780091579', 'wikidata': 'https://www.wikidata.org/wiki/Q9377', 'display_name': 'Kidney', 'level': 2, 'score': 0.1990149}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.15654877}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.13508847}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.07526618}], 'mesh': [{'descriptor_ui': 'D003928', 'descriptor_name': 'Diabetic Nephropathies', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D005355', 'descriptor_name': 'Fibrosis', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D062085', 'descriptor_name': 'RNA, Long Noncoding', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D056564', 'descriptor_name': 'Sirtuin 1', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000375', 'descriptor_name': 'Aging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060565', 'descriptor_name': 'Argonaute Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D060565', 'descriptor_name': 'Argonaute Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060565', 'descriptor_name': 'Argonaute Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003921', 'descriptor_name': 'Diabetes Mellitus, Experimental', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003921', 'descriptor_name': 'Diabetes Mellitus, Experimental', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D003928', 'descriptor_name': 'Diabetic Nephropathies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005355', 'descriptor_name': 'Fibrosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017353', 'descriptor_name': 'Gene Deletion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D005947', 'descriptor_name': 'Glucose', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D005947', 'descriptor_name': 'Glucose', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D005947', 'descriptor_name': 'Glucose', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050527', 'descriptor_name': 'Mesangial Cells', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D050527', 'descriptor_name': 'Mesangial Cells', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D050527', 'descriptor_name': 'Mesangial Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D000067996', 'descriptor_name': 'RAW 264.7 Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D062085', 'descriptor_name': 'RNA, Long Noncoding', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D062085', 'descriptor_name': 'RNA, Long Noncoding', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017207', 'descriptor_name': 'Rats, Sprague-Dawley', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056564', 'descriptor_name': 'Sirtuin 1', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D056564', 'descriptor_name': 'Sirtuin 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/aging.102249', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210231119', 'display_name': 'Aging', 'issn_l': '1945-4589', 'issn': ['1945-4589'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc6834398', 'pdf_url': 'https://europepmc.org/articles/pmc6834398?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834398', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/31631065', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/aging.102249', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210231119', 'display_name': 'Aging', 'issn_l': '1945-4589', 'issn': ['1945-4589'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.79, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 31, 'referenced_works': ['https://openalex.org/W1480785638', 'https://openalex.org/W1618818749', 'https://openalex.org/W2091252250', 'https://openalex.org/W2099760082', 'https://openalex.org/W2105731956', 'https://openalex.org/W2253426984', 'https://openalex.org/W2543312576', 'https://openalex.org/W2560315515', 'https://openalex.org/W2612676285', 'https://openalex.org/W2773048598', 'https://openalex.org/W2783548621', 'https://openalex.org/W2800240734', 'https://openalex.org/W2801396070', 'https://openalex.org/W2809113787', 'https://openalex.org/W2862090491', 'https://openalex.org/W2883978878', 'https://openalex.org/W2885095235', 'https://openalex.org/W2886648347', 'https://openalex.org/W2886673880', 'https://openalex.org/W2887154584', 'https://openalex.org/W2892235817', 'https://openalex.org/W2898049555', 'https://openalex.org/W2903923120', 'https://openalex.org/W2905477792', 'https://openalex.org/W2907733478', 'https://openalex.org/W2909474393', 'https://openalex.org/W2911075837', 'https://openalex.org/W2912276967', 'https://openalex.org/W2916252710', 'https://openalex.org/W2996242680', 'https://openalex.org/W4211057538'], 'related_works': ['https://openalex.org/W3162111133', 'https://openalex.org/W3093337086', 'https://openalex.org/W3000023245', 'https://openalex.org/W2999808440', 'https://openalex.org/W2991252237', 'https://openalex.org/W2983746804', 'https://openalex.org/W2944433097', 'https://openalex.org/W2913268581', 'https://openalex.org/W2912601922', 'https://openalex.org/W2400832891'], 'abstract_inverted_index': {'Diabetic': [0], 'nephropathy': [1], '(DN)': [2], 'is': [3, 15], 'one': [4], 'of': [5, 9, 24, 32, 66, 83, 128, 154, 165], 'the': [6, 19, 30, 64, 81, 114, 152, 163], 'leading': [7], 'causes': [8], 'end-stage': [10], 'renal': [11], 'diseases': [12], 'worldwide.This': [13], 'study': [14], 'designed': [16], 'to': [17, 172], 'investigate': [18], 'underlying': [20], 'function': [21], 'and': [22, 73, 93, 118, 134, 138, 170, 175], 'mechanism': [23], 'a': [25, 125], 'novel': [26], 'lncRNA': [27, 36, 56, 103, 149, 158], 'GAS5': [28, 37, 57, 69, 78, 104, 130, 159], 'in': [29, 42, 52, 86, 156, 162, 177], 'progression': [31, 164], 'DN.We': [33], 'found': [34, 147], 'that': [35, 51, 102, 148], 'expression': [38, 58, 82, 133], 'level': [39, 59], 'was': [40, 60, 122, 160], 'decreased': [41], 'type': [43], '2': [44], 'diabetes': [45], '(T2D)': [46], 'with': [47, 50, 63], 'DN': [48, 155, 166], 'compared': [49], 'patients': [53], 'without': [54], 'DN.Moreover,': [55], 'negatively': [61], 'associated': [62], 'severity': [65], 'DN-related': [67], 'complications.lncRNA': [68], 'inhibited': [70, 135], 'MCs': [71, 136], 'proliferation': [72, 137], 'caused': [74], 'G0/1': [75], 'phase': [76], 'arrest.lncRNA': [77], 'overexpression': [79], 'alleviated': [80], 'fibrosis-related': [84], 'protein': [85, 96], 'mesangial': [87], 'cells': [88], '(MCs).The': [89], 'dual-luciferase': [90], 'reporter': [91], 'assay': [92, 99], 'RNA': [94], 'binding': [95], 'immunoprecipitation': [97], '(RIP)': [98], 'results': [100], 'revealed': [101], 'functions': [105], 'as': [106, 124, 142], 'an': [107, 143], 'endogenous': [108], 'sponge': [109], 'for': [110], 'miR-221': [111, 144, 169], 'via': [112], 'both': [113], 'directly': [115], 'targeting': [116], 'way': [117], 'Ago2-dependent': [119], 'manner.Furthermore,': [120], 'SIRT1': [121, 132], 'confirmed': [123], 'target': [126], 'gene': [127], 'miR-221.lncRNA': [129], 'upregulated': [131], 'fibrosis': [139], 'by': [140, 167], 'acting': [141], 'sponge.Finally,': [145], 'we': [146], 'GSA5': [150], 'suppressed': [151], 'development': [153], 'vivo.Thus,': [157], 'involved': [161], 'sponging': [168], 'contributed': [171], 'lncRNA-directed': [173], 'diagnostics': [174], 'therapeutics': [176], 'DN.': [178]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2981743892', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 10}, {'year': 2022, 'cited_by_count': 18}, {'year': 2021, 'cited_by_count': 32}, {'year': 2020, 'cited_by_count': 14}], 'updated_date': '2024-12-09T07:24:58.699994', 'created_date': '2019-11-01'}