Title: Enzyme Technology for Detoxification of Mycotoxins in Animal Feed
Abstract: Chapter 3.2 Enzyme Technology for Detoxification of Mycotoxins in Animal Feed Dieter Moll, Dieter Moll BIOMIN Research Center, Technopark 1, 3430 Tulln, AustriaSearch for more papers by this author Dieter Moll, Dieter Moll BIOMIN Research Center, Technopark 1, 3430 Tulln, AustriaSearch for more papers by this author Book Editor(s):Andreas Vogel, Andreas Vogel c-LEcta GmbH, R&D Enzyme Development, Perlickstr. 5, Leipzig, 04103 GermanySearch for more papers by this authorOliver May, Oliver May DSM Nutritional Products Ltd, Wurmisweg 576, Kaiseraugst, 4303 SwitzerlandSearch for more papers by this author First published: 29 April 2019 https://doi.org/10.1002/9783527813780.ch3_2Citations: 3 AboutPDFPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShareShare a linkShare onFacebookTwitterLinked InRedditWechat Summary Mycotoxins are products of the secondary metabolism of filamentous fungi including Fusarium and Aspergillus species. These fungi colonize crop plants and grains, such as maize, as plant pathogens or saprotrophes. Therefore, grain for use as animal feed is frequently contaminated with deoxynivalenol, aflatoxin, fumonisin, zearalenone, or other mycotoxins. Mycotoxin contamination compromises the natural vigor, productivity, and disease resistance of farmed animals. Despite good agricultural practice and plant resistance breeding, mycotoxin contamination of animal feed remains an extant problem that presents an opportunity for industrial enzyme technology. BIOMIN has pioneered the development of animal feed enzymes for gastrointestinal degradation and detoxification of mycotoxins. One such recombinant enzyme, the fumonisin esterase FUMzyme ®, has been approved by regulatory authorities and is commercially available. This chapter sums up the research and development behind FUMzyme, including enzyme discovery and characterization, development of activity assays, feeding trials and biomarker analysis, enzyme engineering, production, and registration. The state of research and development of recombinant enzyme technology for detoxification of other mycotoxins is also described. Citing Literature Industrial Enzyme Applications RelatedInformation
Publication Year: 2019
Publication Date: 2019-04-29
Language: en
Type: other
Indexed In: ['crossref']
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Cited By Count: 4
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