Publication Information

{'id': 'https://openalex.org/W2970913233', 'doi': 'https://doi.org/10.1016/j.jid.2019.08.439', 'title': 'Differential Lipid Recognition by Mouse versus Human CD300f, Inhibiting Passive Cutaneous Anaphylaxis, Depends on a Single Amino Acid Substitution in its Immunoglobulin-Like Domain', 'display_name': 'Differential Lipid Recognition by Mouse versus Human CD300f, Inhibiting Passive Cutaneous Anaphylaxis, Depends on a Single Amino Acid Substitution in its Immunoglobulin-Like Domain', 'publication_year': 2019, 'publication_date': '2019-08-30', 'ids': {'openalex': 'https://openalex.org/W2970913233', 'doi': 'https://doi.org/10.1016/j.jid.2019.08.439', 'mag': '2970913233', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/31476319'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.jid.2019.08.439', 'pdf_url': 'http://www.jidonline.org/article/S0022202X1933204X/pdf', 'source': {'id': 'https://openalex.org/S28607811', 'display_name': 'Journal of 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2282, 2321, 2323, 2380, 2382, 2426, 2428, 2505, 2507, 2551, 2553, 2653, 2655, 2699, 2701, 2769, 2771, 2815, 2817, 2872, 2874, 2918, 2920, 3098, 3100, 3144, 3146, 3221, 3223, 3267, 3269, 3381, 3383, 3427, 3429, 3600, 3602, 3646, 3648], 'Text': [83, 85, 128, 130, 174, 176, 250, 252, 291, 293, 368, 370, 507, 509, 553, 555, 602, 604, 829, 831, 939, 941, 1438, 1440, 2235, 2237, 2281, 2283, 2322, 2324, 2381, 2383, 2427, 2429, 2506, 2508, 2552, 2554, 2654, 2656, 2700, 2702, 2770, 2772, 2816, 2818, 2873, 2875, 2919, 2921, 3099, 3101, 3145, 3147, 3222, 3224, 3268, 3270, 3382, 3384, 3428, 3430, 3601, 3603, 3647, 3649], 'PDF': [86, 131, 177, 253, 294, 371, 510, 556, 605, 832, 942, 1441, 2238, 2284, 2325, 2384, 2430, 2509, 2555, 2657, 2703, 2773, 2819, 2876, 2922, 3102, 3148, 3225, 3271, 3385, 3431, 3604, 3650], '(54)': [89], '2012Izawa': [95, 474, 2202, 2348, 2473, 2621, 2737, 2840, 3066, 3189, 3349, 3568], 'Maehara': [99, 148, 188, 218, 311, 347, 478, 527, 803, 913, 1412, 2206, 2255, 2290, 2352, 2401, 2477, 2526, 2625, 2674, 2741, 2790, 2844, 2893, 3070, 3119, 3193, 3242, 3353, 3402, 3572, 3621], 'A.': [100, 149, 189, 222, 224, 232, 312, 338, 342, 348, 479, 528, 671, 702, 804, 914, 1413, 1771, 1802, 2207, 2256, 2294, 2296, 2304, 2353, 2402, 2478, 2527, 2626, 2675, 2742, 2791, 2845, 2894, 3071, 3120, 3194, 3243, 3354, 3403, 3573, 3622], 'Takahashi': [101, 150, 300, 480, 529, 805, 915, 1414, 2208, 2257, 2354, 2403, 2479, 2528, 2627, 2676, 2743, 2792, 2846, 2895, 3072, 3121, 3195, 3244, 3355, 3404, 3574, 3623], 'M.': [102, 104, 143, 151, 191, 195, 230, 267, 304, 308, 314, 481, 483, 522, 530, 578, 675, 798, 806, 908, 916, 1407, 1415, 1775, 2209, 2211, 2250, 2258, 2302, 2355, 2357, 2396, 2404, 2480, 2482, 2521, 2529, 2628, 2630, 2669, 2677, 2744, 2746, 2785, 2793, 2847, 2849, 2888, 2896, 3073, 3075, 3114, 3122, 3196, 3198, 3237, 3245, 3356, 3358, 3397, 3405, 3575, 3577, 3616, 3624], 'Isobe': [103, 142, 190, 313, 482, 521, 797, 907, 1406, 2210, 2249, 2356, 2395, 2481, 2520, 2629, 2668, 2745, 2784, 2848, 2887, 3074, 3113, 3197, 3236, 3357, 3396, 3576, 3615], 'Ito': [105, 146, 484, 525, 801, 911, 1410, 2212, 2253, 2358, 2399, 2483, 2524, 2631, 2672, 2747, 2788, 2850, 2891, 3076, 3117, 3199, 3240, 3359, 3400, 3578, 3619], 'S.': [106, 147, 485, 526, 802, 912, 1411, 2213, 2254, 2359, 2400, 2484, 2525, 2632, 2673, 2748, 2789, 2851, 2892, 3077, 3118, 3200, 3241, 3360, 3401, 3579, 3620], 'al.The': [108, 316, 487, 2215, 2361, 2486, 2634, 2750, 2853, 3079, 3202, 3362, 3581], 'LMIR3': [110, 489, 2217, 2363, 2488, 2636, 2752, 2855, 3081, 3204, 3364, 3583], 'negatively': [111, 490, 2218, 2364, 2489, 2637, 2753, 2856, 3082, 3205, 3365, 3584], 'mast': [113, 164, 358, 402, 459, 492, 543, 636, 819, 929, 1162, 1393, 1428, 1449, 1512, 1520, 1533, 1555, 1584, 1624, 1650, 1672, 2220, 2271, 2366, 2417, 2491, 2542, 2639, 2690, 2755, 2806, 2858, 2909, 3084, 3135, 3207, 3258, 3367, 3418, 3586, 3637, 3700, 3735, 3754], 'cell': [114, 165, 359, 403, 460, 493, 544, 637, 820, 845, 885, 897, 930, 1163, 1299, 1320, 1329, 1429, 1585, 2221, 2272, 2367, 2418, 2492, 2543, 2613, 2640, 2691, 2756, 2807, 2859, 2910, 3085, 3136, 3208, 3259, 3368, 3419, 3587, 3638, 3712], 'activation': [115, 461, 494, 2222, 2368, 2493, 2641, 2757, 2860, 3086, 3209, 3369, 3588], 'allergic': [117, 463, 496, 2224, 2370, 2495, 2643, 2759, 2862, 3088, 3211, 3371, 3590], 'by': [119, 205, 282, 498, 593, 1709, 1757, 1901, 2042, 2173, 2226, 2372, 2497, 2597, 2645, 2761, 2829, 2864, 3090, 3213, 3373, 3489, 3592], 'binding': [120, 451, 499, 857, 1124, 1219, 1258, 1289, 1310, 1372, 2227, 2373, 2498, 2646, 2762, 2865, 3091, 3214, 3374, 3593], 'to': [121, 455, 500, 694, 761, 777, 787, 861, 970, 1023, 1117, 1125, 1225, 1230, 1239, 1261, 1267, 1283, 1290, 1340, 1345, 1352, 1354, 1375, 1505, 1558, 1717, 1741, 1763, 1794, 1917, 2018, 2228, 2374, 2499, 2647, 2719, 2763, 2866, 3056, 3092, 3215, 3292, 3375, 3451, 3594, 3672], 'extracellular': [122, 428, 501, 863, 995, 1088, 1579, 2229, 2375, 2500, 2568, 2648, 2764, 2867, 3093, 3216, 3376, 3595], 'ceramide.Immunity.': [123, 502, 2230, 2376, 2501, 2649, 2765, 2868, 3094, 3217, 3377, 3596], '2012;': [124, 503, 2231, 2377, 2502, 2650, 2766, 2869, 3095, 3218, 3378, 3597], '37:': [125, 504, 2232, 2378, 2503, 2651, 2767, 2870, 3096, 3219, 3379, 3598], '827-839Abstract': [126, 505, 2233, 2379, 2504, 2652, 2768, 2871, 3097, 3220, 3380, 3599], '(76)': [134, 513, 2241, 2387, 2512, 2660, 2776, 2879, 3105, 3228, 3388, 3607], '2014Izawa': [140, 519, 795, 905, 1404, 2247, 2393, 2518, 2666, 2782, 2885, 3111, 3234, 3394, 3613], 'Matsukawa': [144, 523, 799, 909, 1408, 2251, 2397, 2522, 2670, 2786, 2889, 3115, 3238, 3398, 3617], 'al.Sphingomyelin': [153, 532, 808, 918, 1417, 2260, 2406, 2531, 2679, 2795, 2898, 3124, 3247, 3407, 3626], 'ceramide': [155, 441, 534, 774, 810, 877, 920, 1226, 1241, 1262, 1273, 1419, 1635, 1661, 2262, 2408, 2533, 2681, 2797, 2900, 2982, 3126, 3249, 3409, 3628], 'are': [156, 535, 811, 921, 1366, 1420, 2016, 2263, 2409, 2534, 2682, 2798, 2901, 3127, 3250, 3410, 3629, 3657], 'physiological': [157, 536, 812, 922, 1421, 2264, 2410, 2535, 2683, 2799, 2902, 3128, 3251, 3411, 3630], 'ligands': [158, 454, 537, 751, 813, 860, 923, 974, 1422, 1728, 2265, 2411, 2536, 2684, 2800, 2903, 3129, 3252, 3412, 3631], 'for': [159, 434, 446, 538, 662, 733, 814, 924, 1198, 1256, 1368, 1423, 1701, 1833, 1856, 2035, 2266, 2412, 2537, 2606, 2685, 2801, 2904, 3130, 3253, 3319, 3413, 3632], 'human': [160, 447, 539, 815, 925, 1424, 1850, 1893, 2267, 2413, 2538, 2686, 2802, 2905, 3131, 3254, 3414, 3633], 'LMIR3/CD300f,': [161, 540, 816, 926, 1425, 2268, 2414, 2539, 2687, 2803, 2906, 3132, 3255, 3415, 3634], 'inhibiting': [162, 541, 817, 927, 1426, 1582, 2269, 2415, 2540, 2688, 2804, 2907, 3133, 3256, 3416, 3635], 'FcεRI-mediated': [163, 542, 818, 928, 1427, 2270, 2416, 2541, 2689, 2805, 2908, 3134, 3257, 3417, 3636], 'activation.J': [166, 360, 545, 821, 931, 1430, 2273, 2419, 2544, 2692, 2808, 2911, 3137, 3260, 3420, 3639], 'Allergy': [167, 361, 546, 822, 932, 1431, 2274, 2420, 2545, 2607, 2693, 2809, 2912, 3138, 3261, 3421, 3640], 'Clin': [168, 362, 547, 823, 933, 1432, 2275, 2421, 2546, 2694, 2810, 2913, 3139, 3262, 3422, 3641], '2014;': [170, 287, 407, 549, 598, 641, 825, 935, 1167, 1434, 2277, 2423, 2548, 2696, 2812, 2915, 3141, 3264, 3424, 3643], '133:': [171, 550, 826, 936, 1435, 2278, 2424, 2549, 2697, 2813, 2916, 3142, 3265, 3425, 3644], '270-273.e1Abstract': [172, 551, 827, 937, 1436, 2279, 2425, 2550, 2698, 2814, 2917, 3143, 3266, 3426, 3645], '(0)': [180, 559, 835, 945, 1444, 2287, 2433, 2558, 2706, 2822, 2925, 3151, 3274, 3434, 3653], '2017Izawa': [186], 'Yasuda': [192], 'Urai': [194, 307], 'Hoshino': [196], 'al.Disrupting': [199], 'ceramide-CD300f': [200, 237, 2309], 'interaction': [201, 238, 318, 1575, 2310], 'prevents': [202], 'septic': [203], 'peritonitis': [204], 'stimulating': [206], 'neutrophil': [207, 323], 'recruitment.Sci': [208, 324], 'Rep.': [209], '2017;': [210], '7:': [211, 288, 599], '4298Crossref': [212], '(18)': [215], '2018Maehara': [221, 2293], 'Kaitani': [223, 341, 2295], 'Shiba': [227, 2299], 'E.': [228, 981, 1074, 2300], 'Nagamine': [229, 2301], 'Takamori': [231, 334, 2303], 'al.Role': [234, 2306], 'the': [236, 427, 688, 763, 770, 843, 856, 862, 952, 956, 963, 972, 994, 998, 1047, 1087, 1091, 1113, 1129, 1176, 1184, 1199, 1250, 1257, 1279, 1296, 1306, 1309, 1325, 1336, 1348, 1361, 1369, 1381, 1479, 1499, 1515, 1536, 1567, 1574, 1641, 1648, 1656, 1664, 1680, 1684, 1694, 1702, 1720, 1748, 1758, 1788, 1846, 1857, 1874, 1902, 2019, 2174, 2308, 2577, 2581, 2593, 3041, 3057, 3278, 3299, 3313, 3324, 3442, 3458, 3460, 3479, 3482, 3491, 3508, 3516, 3527, 3553, 3676], 'in': [239, 354, 398, 426, 632, 854, 882, 895, 1120, 1134, 1158, 1318, 1370, 1382, 1399, 1514, 1532, 1554, 1573, 1626, 1644, 1667, 1683, 1703, 1747, 1895, 2311, 3281, 3312, 3507, 3525, 3552, 3688, 3714, 3748], 'Gram-negative': [240, 2312], 'bacterial': [241, 2313], 'skin': [242, 1501, 1517, 1629, 2314, 3555, 3716], 'infections.J': [243, 2315], 'Invest': [244, 2316], 'Dermatol.': [245, 2317], '2018;': [246, 2318], '138:': [247, 2319], '1221-1224Abstract': [248, 2320], '(6)': [256, 2328], 'Moshkovits': [259], '2014Moshkovits': [262, 573], 'I.': [263, 574], 'Shik': [264, 575], 'D.': [265, 269, 576, 580, 985, 1078], 'Itan': [266, 577], 'Karo-Atar': [268, 579], 'Bernshtein': [270, 581], 'B.': [271, 582], 'Hershko': [272, 583], 'A.Y.': [273, 584], 'al.CMRF35-like': [275, 586], 'molecule': [276, 587], '1': [277, 588, 3021, 3035, 3540], '(CLM-1)': [278, 589], 'eosinophil': [280, 591], 'homeostasis': [281, 592], 'suppressing': [283, 594], 'cellular': [284, 595, 731, 1831], 'chemotaxis.Mucosal': [285, 596], '292-303Abstract': [289, 600], '(28)': [297, 608], '2019Takahashi': [303], 'phytosphingosine-CD300b': [317], 'promotes': [319], 'zymosan-induced,': [320], 'nitric': [321], 'oxide-dependent': [322], 'Signal.': [325], '2019;': [326, 364], '12:': [327], 'eaar5514Crossref': [328], '(8)': [331], '2019Takamori': [337], 'Ando': [343], 'Okamoto': [345], 'al.Identification': [350], 'mechanisms': [353, 397, 631, 1157], 'pseudo-allergy': [355, 399, 633, 1159], 'involving': [356, 400, 634, 1160, 1252, 1364, 1569, 1697, 1852], 'Mrgprb2/MRGPRX2-mediated': [357, 401, 635, 1161], '143:': [365], '1231-1235.e12Abstract': [366], '(17)': [374], 'Tian': [377, 611], '2014Tian': [380, 614, 1140], 'L.': [381, 615, 1141], 'Choi': [382, 616, 1142], 'S.C.': [383, 617, 1143], 'Murakami': [384, 618, 678, 1144, 1778], 'Allen': [386, 620, 1146], 'Morse': [388, 622, 1148], '3rd,': [389, 623, 1149], 'H.C.': [390, 624, 1150], 'Qi': [391, 625, 1151], 'C.F.': [392, 626, 1152], 'al.p85al.miK': [394, 628, 1154], '∖l': [395, 629, 1155], '"c10"unolbitory': [396, 630, 1156], 'activationeramideion': [404, 638, 1164], 'protei.Nat': [405, 639, 1165], 'Commun.': [406, 640, 1166], '5:': [408, 642, 1168], '3146Crossref': [409, 643, 1169], '(58)': [412, 646, 1172], 'Scholar).': [414, 561, 648, 743, 837, 947, 1015, 1108, 1174, 1446, 1843, 2330, 2435, 2560, 2708, 2824, 2927, 3153, 3276, 3436, 3655], 'CD300f': [415, 436, 448, 456, 953, 1475, 1550, 1605, 1851, 1872, 1894, 3687], 'an': [417, 659, 1868, 2567, 3046], 'contains': [421], 'single': [423, 1863], 'immunoglobulin-like': [424, 964, 1869], 'domain': [425, 864, 965, 996, 1089, 1870, 2569], 'region.': [429], 'Ceramide': [430], 'ligand': [433, 445, 757, 1135, 1201], '(mCD300f),': [437], 'whereas': [438, 782, 887], 'sphingomyelin': [439, 783, 889, 1231, 1244, 1268, 1291, 1312, 1355, 1376, 1638, 1675, 1707, 1860, 3028], 'act': [442], '(hCD300f).': [449], 'The': [450, 990, 1083, 1109, 1218, 1527, 2008, 2928, 3333, 3531], 'these': [453, 1179, 1482, 1495, 1617, 1690], 'inhibits': [457], 'IgE-mediated': [458, 1583], 'responses,': [464], 'including': [465], 'passive': [466, 3773], 'cutaneous': [467, 3774], 'anaphylaxis': [468], '(PCA)': [469], '(Izawa': [471, 792, 902, 1401, 2199, 2345, 2470, 2618, 2734, 2837, 3063, 3186, 3346, 3565], 'mCD300f': [562, 746, 779, 866, 1053, 1121, 1194, 1204, 1260, 1286, 1577, 1732], 'also': [563, 1739, 3181], 'recognizes': [564], 'phosphatidylserine': [565], 'exposed': [566], 'on': [567, 769, 1002, 1095, 1478, 1498, 1606], 'apoptotic': [568, 1126], 'cells': [569, 1004, 1097, 1127, 1450, 1513, 1534, 1556, 1625, 1651, 2710, 3551], '(Moshkovits': [570], 'In': [649, 874, 1844, 3496], 'addition,': [650, 1264], 'mCD300f,': [651], 'but': [652, 1228], 'not': [653, 1229, 1678], 'hCD300f,': [654, 781], 'was': [655, 2040, 2453, 2467, 2574, 2955, 2986, 3000, 3014, 3032, 3157, 3180, 3290, 3338, 3341, 3670], 'recently': [656], 'identified': [657], 'entry': [660, 1749], 'murine': [663, 692, 1792], 'norovirus': [664], '(Haga': [665, 1765], '2016Haga': [668, 1768], 'Fujimoto': [670, 1770], 'Takai-Todaka': [672, 1772], 'R.': [673, 1773], 'Miki': [674, 1774], 'Doan': [676, 1776], 'Y.H.': [677, 1777], 'molecules': [683, 1783], 'CD300lf': [684, 1784], 'CD300ld': [686, 1786], 'within': [687, 1787], 'enable': [691, 1791], 'noroviruses': [693, 1793], 'infect': [695, 1795], 'cells.Proc': [696, 1796], 'Natl': [697, 1797], 'Acad': [698, 1798], 'Sci': [699, 1799], 'U': [700, 1800], 'S': [701, 1801], '2016;': [703, 736, 1803, 1836], '113:': [704, 1804], 'E6248-E6255Crossref': [705, 1805], '(106)': [708, 1808], 'Orchard': [711, 1811], '2016Orchard': [714, 1814], 'R.C.': [715, 1815], 'Wilen': [716, 1816], 'C.B.': [717, 1817], 'Doench': [718, 1818], 'J.G.': [719, 1819], 'Baldridge': [720, 1820], 'M.T.': [721, 1821], 'McCune': [722, 1822], 'B.T.': [723, 1823], 'Lee': [724, 1824], 'Y.C.': [725, 1825], 'al.Discovery': [727, 1827], 'proteinaceous': [730, 1830], 'Norovirus.Science.': [735, 1835], '353:': [737, 1837], '933-936Crossref': [738, 1838], '(177)': [741, 1841], 'Thus,': [744], 'both': [745, 778, 883], 'hCD300f': [748, 788, 868, 1020, 1065, 1190, 1351, 1374, 1723, 1744, 1764], 'share': [749], 'similar': [750, 1509, 1886], 'functions,': [753], 'while': [754], 'exhibiting': [755], 'differential': [756, 1200], 'specificities.': [758], 'We': [759, 1207, 1507, 2015], 'aimed': [760], 'elucidate': [762], 'underlying': [764], 'molecular': [765], 'mechanisms:': [766], 'we': [767, 841, 1181, 1294, 1391, 1588], 'focused': [768], 'previous': [771, 1110], 'finding': [772, 1111], '(d18:1/24:0)': [775, 878, 1227, 1242, 1274], 'binds': [776, 786], '(d18:1/18:0)': [784, 890, 1245, 1313, 1356, 1708], 'only': [785, 894, 1314], '(Supplementary': [789, 899, 1485, 1524, 1609, 1630, 1652], 'Figure': [790, 900, 1486, 1525, 1610, 1631, 1653, 3678, 3704, 3710, 3739, 3745, 3781], 'S1a)': [791], 'To': [838, 1378, 2436, 2561], 'this': [839, 1132, 1386, 1734, 1918], 'end,': [840], 'used': [842, 1392, 2195, 3182], 'reporter': [844, 884, 1298, 1328], 'lines': [846, 898, 1300, 1321, 1330, 2614], '2B4-mCD300f-wild-type': [847], '(WT)–green': [848], 'fluorescent': [849], 'protein': [850], '(GFP)': [851], '2B4-hCD300f-WT-GFP,': [853], 'which': [855, 1545, 1753, 1882], 'specific': [859, 1735], 'could': [869], 'induce': [870], 'GFP': [871, 880, 892, 1316], 'expression,': [872], 'respectively.': [873, 2727], 'fact,': [875], 'plate-coated': [876, 888], 'induced': [879, 891, 1315], 'expression': [881, 893, 1317, 3680], 'lines,': [886], '2B4-hCD300f-GFP': [896, 2612], 'S1b)': [901], 'One': [948], 'important': [949], 'feature': [950], 'structure': [954, 992, 1018, 1085, 1133, 1251, 1388, 1568, 1696, 1848], 'formation': [957], 'prominent': [960], 'protrusion': [961, 1017, 1362, 1387, 1695, 1847], 'from': [962, 1454, 2044, 2944, 2956, 2967, 2976, 2988, 3002, 3016], 'has': [967], 'been': [968], 'postulated': [969], 'recognize': [971, 1725], 'potential': [973], '(Márquez': [975, 1068], '2007Márquez': [978, 1071], 'J.A.': [979, 1072], 'Galfré': [980, 1073], 'Dupeux': [982, 1075], 'Flot': [984, 1077], 'Moran': [986, 1079], 'O.': [987, 1080], 'Dimasi': [988, 1081], 'N.': [989, 1082], 'crystal': [991, 1084], 'inhibitor': [999, 1092], 'expressed': [1001, 1094, 3658], 'IREM-1.J': [1005, 1098], 'Mol': [1006, 1099], 'Biol.': [1007, 1100], '367:': [1009, 1102], '310-318Crossref': [1010, 1103], '(23)': [1013, 1106], 'This': [1016, 2038], 'presumed': [1022], 'be': [1024, 1196, 1755, 1921], 'composed': [1025], 'several': [1027, 1210], 'key': [1028], 'amino': [1029, 1049, 1864], 'acids': [1030], 'include': [1032], 'tryptophan-52,': [1033], 'tryptophan-59,': [1034], 'isoleucine-64,': [1035], 'lysine': [1036], '(K)-67,': [1037], 'tryptophan-107,': [1038], 'glutamic': [1039], 'acid': [1040, 1050, 1865], '(E)-111,': [1041], 'aspartate': [1043], '(D)-116.': [1044], 'Among': [1045], 'them,': [1046], 'corresponding': [1048], 'residues': [1051, 1187], '(tyrosine-53,': [1054], 'Glutamine-60,': [1055], 'Threonine-65,': [1056], 'E-68,': [1057], 'threonine-112)': [1059], 'were': [1060, 1452, 1458, 1476, 1492, 1614, 1899, 2171, 2194, 2340, 2595, 2615, 2711, 2729, 2827, 2931, 2942, 2966, 2974, 3043, 3301, 3326, 3439, 3462, 3487, 3504, 3518, 3529, 3536, 3556], 'different': [1061, 1888], 'than': [1062], 'those': [1063, 1543], '(Figure': [1066, 1235, 1246, 1275, 1322, 1357, 1561, 1687], '1a)': [1067], 'substitution': [1114, 1280, 1337, 1866], 'D-117': [1116, 1253], 'alanine': [1118], '(A)': [1119], 'abolishes': [1122], 'its': [1123], 'underscores': [1128], 'significance': [1130], 'recognition': [1136, 1705, 1858], '(Tian': [1137], 'On': [1175, 1655], 'basis': [1177], 'concepts,': [1180], 'hypothesized': [1182], 'oppositely': [1185], 'charged': [1186], 'K-67': [1188, 1339, 1853], 'versus': [1191, 1892], 'E-68': [1192, 1282], 'would': [1195], 'responsible': [1197], 'specificities': [1202], 'between': [1203, 1576, 1878, 3675], 'hCD300f.': [1206, 1710], 'then': [1208], 'generated': [1209, 1295, 1453, 1589, 2730, 2828, 3044], 'Fc': [1211, 2466, 2583, 3311], 'fusion': [1212], 'proteins:': [1213], 'mCD300f-WT-Fc,': [1214, 3307], 'mCD300f-E68K-Fc,': [1215], 'mCD300f-D117A-Fc.': [1217], 'assay': [1220], 'showed': [1221, 1334, 1529], 'mCD300f-WT-Fc': [1223], 'bound': [1224, 1238, 1266], '(d18:1/18:0),': [1232, 1269], 'expected': [1234], '1a).': [1236], 'mCD300f-D117A-Fc': [1237], 'neither': [1240, 1549], 'nor': [1243, 1552], '1b),': [1247, 1276], 'indicating': [1248], 'essential': [1255, 1367, 1700], '(d18:1/24:0).In': [1263], 'mCD300f-E68K-Fc': [1265], 'well': [1271], 'demonstrating': [1277], 'K': [1284, 2051, 2058, 2064, 2073, 2092, 2107, 2112, 2118, 2128, 2138, 2160], 'rendered': [1285], 'capable': [1287], '(d18:1/18:0).': [1292, 1377, 1861], 'Next,': [1293], 'additional': [1297], '2B4-mCD300f-D117A-GFP': [1301], '2B4-mCD300f-E68K-GFP.': [1303], 'Consistent': [1304], 'with': [1305, 1460, 1494, 1542, 1593, 1616, 1634, 1647, 1660, 1670, 1731, 2455, 2713, 3034, 3159, 3168, 3303, 3328, 3441, 3465, 3511, 3520, 3539, 3558, 3723, 3752, 3757], 'results': [1307, 1326, 1528, 1564, 1691], 'assays,': [1311], '2B4-mCD300f-E68K-GFP': [1319], '1c).': [1323], 'Moreover,': [1324], 'using': [1327, 2462, 3045], '2B4-hCD300f-K67E-GFP': [1331], '2B4-hCD300f-D116A-GFP': [1333], 'E': [1341], 'D-116': [1344], 'A': [1346, 1862, 2053, 2060, 2075, 2109, 2120, 2130, 2140, 2153, 3664], 'dampened': [1347], 'ability': [1349], 'bind': [1353, 1762], '1d).': [1358], 'Taken': [1359], 'together,': [1360], 'structures': [1363], 'K67': [1365, 1698], 'vitro': [1371], 'next': [1379], 'examine': [1380], 'vivo': [1383, 1704], 'role': [1384], 'CD300f,': [1390], 'cell–': [1394], 'IgE-dependent': [1396], 'PCA': [1397, 1537, 1642, 1665, 1681, 3340], 'reactions': [1398], 'mice': [1400, 1456, 1491, 1523, 1613, 1645, 1668, 1686, 2193, 3438, 3461, 3535, 3719, 3750], 'Bone': [1447], 'marrow–derived': [1448, 3699, 3734], '(BMMCs)': [1451], 'mCD300f-deficient': [1455, 1590], 'transduced': [1459, 1483, 1519, 1592, 2712, 3725], 'mCD300f-WT,': [1461], 'mCD300f-E68K,': [1462], 'mCD300f-D117A,': [1463], 'or': [1464, 1595, 1603, 1637, 1887, 2334, 2338, 2446, 2451, 2459, 2564, 2572, 2717, 2724, 3030, 3285, 3310], 'mock': [1466], 'treatment.': [1467], 'Equivalent': [1468], 'levels': [1469, 1540, 1599, 3681], 'FcεRIα,': [1471, 1601, 3683], 'c-Kit,': [1472, 1602], 'Flag-tagged': [1474, 1604, 3686], 'found': [1477, 1508, 1922], 'surface': [1480], 'BMMCs': [1484, 1591, 2728, 3726], 'S2).': [1487, 1611], 'Mast': [1488, 3550], 'cell–deficient': [1489], 'Mcpt5-Cre/R-DTA': [1490, 1522, 1612, 2192, 3534, 3718, 3749], 'reconstituted': [1493, 1615, 1646, 1669], 'BMMC': [1496, 1618, 2825, 3544, 3690], 'transfectants': [1497, 2826, 3545], 'ear': [1500, 1516, 1628, 3554, 3715], 'before': [1502, 3548], 'being': [1503], 'subjected': [1504], 'PCA.': [1506, 3549], 'numbers': [1510, 1622, 3713], 'cells–engrafted': [1521], 'S3).': [1526, 1632], 'mCD300f-E68K': [1531, 2571], 'suppressed': [1535, 1663], 'at': [1539, 1544, 1923, 3335, 3493], 'comparable': [1541], 'mCD300f-WT': [1546], 'did.': [1547], 'However,': [1548], 'deficiency': [1551], 'mCD300f-D117A': [1553, 2573], 'failed': [1557], 'do': [1559], 'so': [1560], '2a).': [1562], 'These': [1563], 'indicate': [1565, 1692], 'D117': [1570], 'pivotal': [1572, 1855], 'lipid': [1580, 1875, 3025, 3502], 'ligands,': [1581], 'activation.': [1586], 'Furthermore,': [1587], 'hCD300f-WT': [1594], 'hCD300f-K67E,': [1596], 'expressing': [1597], 'equivalent': [1598, 1621], 'their': [1607, 1627], 'surfaces': [1608], 'transfectants,': [1619], 'displaying': [1620], 'Pretreatment': [1633], '(d18:1/24:0)-vesicles': [1636, 1662], '(d18:1/18:0)-vesicles': [1639, 1676], 'inhibited': [1640], 'hCD300f-WT–transduced': [1649], 'S4).': [1654], 'other': [1657], 'hand,': [1658], 'pretreatment': [1659], 'hCD300f-K67E-transduced': [1671], 'cells;': [1673], 'however,': [1674], 'did': [1677], 'suppress': [1679], 'same': [1685], '2b).': [1688], 'Accordingly,': [1689], 'Although': [1711], 'further': [1712], 'structural': [1713], 'needed': [1716], 'completely': [1718], 'understand': [1719], 'relevant': [1721], 'mechanisms,': [1722], 'might': [1724, 1754], 'more': [1726], 'diverse': [1727], 'compared': [1730], 'via': [1733], 'structure.': [1736], 'It': [1737], 'possible': [1740], 'speculate': [1742], 'involved': [1746], 'certain': [1751], 'viruses,': [1752], 'prevented': [1756], 'drugs': [1759], 'specifically': [1761], 'conclusion,': [1845], 'determines': [1873], 'ligand–binding': [1876], 'specificity': [1877], 'human,': [1881], 'will': [1883], 'help': [1884], 'clarify': [1885], 'roles': [1889], 'immunity.': [1896], 'All': [1897, 2169, 2591], 'procedures': [1898, 2170], 'approved': [1900, 2172], 'Institutional': [1903, 2175], 'Review': [1904, 2135, 2176], 'Committee': [1905, 2177], 'Juntendo': [1907, 2029, 2179], 'University': [1908, 2030, 2180], '(approval': [1909, 2181], 'no.': [1910, 2182], '290104,': [1911, 2183], '300132,': [1912, 2184], '310047).': [1914, 2186], 'Datasets': [1915], 'related': [1916], 'article': [1919], 'https://www.ncbi.nlm.nih.gov/protein/AAP57942': [1924], 'https://www.ncbi.nlm.nih.gov/nuccore/AY457047.': [1926], 'Kumi': [1927], 'Izawa:': [1928], 'http://orcid.org/0000-0003-4746-7225': [1929], 'Ayako': [1930], 'Kaitani:': [1931], 'http://orcid.org/0000-0003-0660-0480': [1932], 'Tomoaki': [1933], 'Ando:': [1934, 1946], 'http://orcid.org/0000-0002-8548-4424': [1935], 'Akie': [1936], 'Maehara:': [1937], 'http://orcid.org/0000-0002-9067-6471': [1938], 'Masakazu': [1939], 'Nagamine:': [1940], 'http://orcid.org/0000-0002-9691-3079': [1941], 'Hiromichi': [1942], 'Yamada:': [1943], 'http://orcid.org/0000-0002-0753-0827': [1944], 'Taiki': [1945], 'http://orcid.org/0000-0002-6012-5484': [1947], 'Takuma': [1948], 'Ide:': [1949], 'http://orcid.org/0000-0001-6196-2965': [1950], 'Moe': [1951], 'Matsuzawa:': [1952], 'http://orcid.org/0000-0001-6486-7525': [1953], 'Yoko': [1954], 'Okamoto:': [1955], 'http://orcid.org/0000-0001-7857-0909': [1956], 'Enzhi': [1957], 'Yin:': [1958], 'http://orcid.org/0000-0002-4265-0058': [1959], 'Saaya': [1960], 'Fukase:': [1961], 'http://orcid.org/0000-0002-3643-6004': [1962], 'Hexing': [1963], 'Wang:': [1964], 'http://orcid.org/0000-0001-9215-4821': [1965], 'Anna': [1966], 'Kamei:': [1967], 'http://orcid.org/0000-0001-6309-3337': [1968], 'Shino': [1969], 'Uchida:': [1970, 1979], 'http://orcid.org/0000-0001-6428-3773': [1971], 'Keiko': [1972], 'Maeda:': [1973], 'http://orcid.org/0000-0003-2127-4687': [1974], 'Nobuhiro': [1975], 'Nakano:': [1976], 'http://orcid.org/0000-0002-5317-5950': [1977], 'Koichiro': [1978], 'http://orcid.org/0000-0003-0645-8373': [1980], 'Naoto': [1981], 'Tamura:': [1982], 'http://orcid.org/0000-0003-1729-2954': [1983], 'Katsuhisa': [1984], 'Ikeda:': [1985], 'http://orcid.org/0000-0001-8920-9916': [1986], 'Nobuyuki': [1987], 'Ebihara:': [1988], 'http://orcid.org/0000-0002-6772-6549': [1989], 'Toshiaki': [1990], 'Shimizu:': [1991], 'http://orcid.org/0000-0003-0364-0022': [1992], 'David': [1993], 'Voehringer:': [1994], 'http://orcid.org/0000-0001-6650-0639': [1995], 'Axel': [1996], 'Roers:': [1997], 'http://orcid.org/0000-0003-1806-6158': [1998], 'Hideoki': [1999], 'Ogawa:': [2000], 'http://orcid.org/0000-0003-4268-8790': [2001], 'Ko': [2002], 'Okumura:': [2003], 'http://orcid.org/0000-0003-3238-6422': [2004], 'Jiro': [2005], 'Kitaura:': [2006], 'http://orcid.org/0000-0002-5083-8368': [2007], 'authors': [2009], 'state': [2010], 'no': [2011], 'conflict': [2012], 'interest.': [2014], 'grateful': [2017], 'Laboratory': [2020], 'Morphology': [2022], 'Image': [2024, 3703, 3738, 3780], 'Analysis,': [2025], 'Research': [2026, 2604, 2990], 'Support': [2027], 'Center,': [2028], 'Graduate': [2031], 'School': [2032], 'Medicine': [2034], 'technical': [2036], 'assistance.': [2037], 'work': [2039], 'supported': [2041], 'grants': [2043], 'JSPS': [2045], 'KAKENHI': [2046], '(26293231': [2047], '17H04217).': [2049], 'Conceptualization:': [2050], 'Izawa,': [2052, 2059, 2074, 2093, 2108, 2119, 2129, 2139], 'Kaitani,': [2054, 2061, 2076, 2110, 2121, 2131, 2141], 'JK;': [2055, 2068], 'Formal': [2056], 'Analysis:': [2057], 'TA,': [2062, 2077, 2142, 2146], 'NT,': [2063, 2111, 2159], 'Ikeda,': [2065, 2113, 2161], 'NE,': [2066, 2114, 2162], 'TS,': [2067, 2115], 'Funding': [2069], 'Acquisition:': [2070], 'JK.': [2071, 2094, 2097, 2101, 2105, 2116, 2122, 2132, 2168], 'Investigation:': [2072], 'AM,': [2078, 2143], 'MN,': [2079, 2144], 'NN,': [2080, 2157], 'KU,': [2081, 2158], 'HY,': [2082, 2145], 'TI,': [2083, 2147], 'YO,': [2084, 2149], 'EY,': [2085, 2150], 'SF,': [2086, 2151], 'KM,': [2087, 2156], 'HW,': [2088, 2152], 'SU,': [2089, 2155], 'KM.': [2090], 'Methodology:': [2091], 'Project': [2095], 'Administration:': [2096], 'Resources:': [2098], 'DV,': [2099, 2164], 'AR,': [2100, 2165], 'Supervision:': [2102], 'HO,': [2103, 2166], 'KO,': [2104, 2167], 'Validation:': [2106], 'Visualization:': [2117], 'Writing': [2123, 2133], '-': [2124, 2134], 'Original': [2125], 'Draft': [2126], 'Preparation:': [2127], 'Editing:': [2137], 'MM,': [2148], 'Kamei,': [2154], 'TX,': [2163], 'C57BL/6J': [2187], 'mice,': [2188, 2190], 'CD300f−/−': [2189], 'previously': [2197, 2343, 2468, 2616, 2732, 2835, 3061, 3184, 3344], 'described': [2198, 2344, 2469, 2617, 2733, 2836, 3062, 3185, 3345, 3564], 'pMXs-IRES-puror': [2331], '(pMXs-IP),': [2332], 'pMXs-Flag-mCD300f': [2333, 2337], 'hCD300f-IP,': [2335], 'hCD300f-CD3ζ-IP': [2339], 'constructed': [2341], 'generate': [2437, 2562, 2720], 'pMXs-Flag-mCD300f-E68K,': [2439, 2443], 'Flag-mCD300f-D117A,': [2440, 2444], 'Flag-hCD300f-K67E-IP': [2441], 'Flag-hCD300f-K67E,': [2445], 'Flag-hCD300f-D116A-CD3ζ-IP,': [2447], 'mCD300f-E68,': [2448], 'mCD300f-D117,': [2449], 'hCD300f-K67,': [2450], 'hCD300f-D116': [2452], 'replaced': [2454], 'K,': [2456], 'A,': [2457, 2460], 'E,': [2458], 'respectively,': [2461], 'PCR-mediated': [2463], 'mutagenesis.': [2464], 'pME18S-mCD300f-hIgG1': [2465], 'pME18S-mCD300f-E68K': [2563], 'D117A-hIgG1': [2565], 'Fc,': [2566], 'inserted': [2575], 'into': [2576], 'cloning': [2578], 'sites': [2579], 'pME18S-hIgG1': [2582], 'vector': [2584], '(H.': [2585], 'Arase,': [2586], 'Osaka': [2587], 'University,': [2588], 'Osaka,': [2589], 'Japan).': [2590], 'constructs': [2594], 'verified': [2596], 'DNA': [2598], 'sequencing.': [2599], '2B4-GFP': [2600, 2709], '(T.': [2601], 'Saito,': [2602], 'RIKEN': [2603], 'Center': [2605], 'Immunology),': [2609], '2B4-mCD300f-GFP,': [2610], 'mCD300f-E68K-CD3ζ,': [2714], 'mCD300f-D117A-CD3ζ,': [2715], 'hCD300f-K67E-CD3ζ,': [2716], 'hCD300f-D116A-CD3ζ': [2718], '2B4-mCD300f-E68K-GFP,': [2721], '2B4-mCD300f-D117A-GFP,': [2722], '2B4-hCD300f-K67E-GFP,': [2723], '2B4-hCD300f-D117A-GFP': [2725], 'cells,': [2726, 3755], 'retroviral': [2830], 'transfection': [2831], 'infection': [2833], 'following': [2929], 'antibodies': [2930], 'used:': [2932], 'Anti-Flag': [2933], 'IgG1': [2934, 2939], 'Ab': [2935, 2940, 2954], '(M2),': [2936], '(MOPC21)': [2941], 'purchased': [2943], 'Sigma-Aldrich': [2945], '(St.': [2946], 'Louis,': [2947], 'MO).': [2948], 'R-phycoerythrin-conjugated': [2949, 2963], 'anti-mouse': [2950], 'IgG': [2951], 'goat': [2952], 'F(ab′)2': [2953], 'Beckman': [2957], 'Coulter.': [2958], 'FITC-conjugated': [2959], 'anti-FcεRIα': [2960], '(MAR-1)': [2961], 'anti-c-kit': [2964], '(2B8)': [2965], 'Thermo': [2968], 'Fisher': [2969], 'Inc': [2970, 2992, 3005], '(Waltham,': [2971], 'MA).': [2972], 'Cytokines': [2973], 'obtained': [2975, 2987, 3001, 3015], 'R&D': [2977], 'Systems': [2978], '(Minneapolis,': [2979], 'MN).': [2980], 'C-24': [2981], '(ceramide': [2983, 3026], '[d18:1/24:0];': [2984], 'C42H83NO3)': [2985], 'Toronto': [2989], 'Chemicals,': [2991], '(North': [2993], 'York,': [2994], 'ON,': [2995], 'Canada).': [2996], '1,2-Dipalmitoyl-sn-glycero-3-phosphocholine': [2997], '(phosphatidylcholine;': [2998], 'PC)': [2999, 3031], 'Echelon': [3003], 'Biosciences': [3004], '(Salt': [3006], 'Lake': [3007], 'City,': [3008], 'UT).': [3009], 'Sphingomyelin': [3010], '(sphingomyelin': [3011], '[d18:1/18:0];': [3012], 'C41H83N2O6P)': [3013], 'ENZO': [3017], '(Farmingdale,': [3018], 'NY).': [3019], 'After': [3020, 3297, 3322, 3515], 'mg': [3022], 'dry': [3024], '(d18:1/24:0],': [3027], '[d18:1/18:0],': [3029], 'hydrated': [3033], 'ml': [3036], 'phosphate': [3038], 'buffered': [3039], 'saline,': [3040], 'vesicles': [3042, 3503, 3759], 'Avanti': [3047], 'Mini-Extruder': [3048], '(Avanti': [3049], 'Polar': [3050], 'Lipids,': [3051], 'Inc,': [3052], 'Alabaster,': [3053], 'AL)': [3054], 'according': [3055], "manufacturer's": [3058], 'instructions': [3059], 'Flow': [3154], 'cytometric': [3155], 'performed': [3158, 3342, 3671], 'FACSCalibur': [3161], '(BD': [3162], 'Biosciences,': [3163], 'San': [3164], 'Jose,': [3165], 'CA)': [3166], 'equipped': [3167], 'CellQuest': [3169], 'software': [3170, 3173], 'FlowJo': [3172], '(Tree': [3174], 'Star,': [3175], 'Ashland,': [3176], 'OR).': [3177], 'Solid-phase': [3178], 'ELISA': [3179, 3293], 'Briefly,': [3277, 3437], 'indicated': [3279, 3689, 3724, 3758], 'lipids': [3280], 'methanol': [3282, 3286], '(10': [3283], 'μg/ml)': [3284], 'control': [3289], 'added': [3291], 'plates': [3294, 3300, 3325], 'air-dried.': [3296], 'washing,': [3298, 3323], 'incubated': [3302, 3327], '10': [3304, 3499], 'μM': [3305], 'mCD300-E68K-Fc,': [3308], 'mCD300f-D117A-Fc,': [3309], 'presence': [3314], '0.5': [3316], 'mM': [3317], 'CaCl2': [3318], '120': [3320], 'minutes.': [3321], 'peroxidase-conjugated': [3329], 'anti-human': [3330], 'Ig': [3331], '(Sigma).': [3332], 'absorbance': [3334, 3492], '450': [3336], 'nm': [3337], 'measured.': [3339], 'sensitized': [3440], 'intradermal': [3443, 3721], 'injection': [3444], '50': [3446], 'ng': [3447], 'anti-2,4-dintrophenyl': [3448], 'IgE': [3449, 3513], '(H1-ε-26)': [3450], 'each': [3452], 'ear.': [3453], 'Then': [3454], '24': [3455], 'hours': [3456], 'after': [3457, 3478, 3720], 'sensitization,': [3459], 'injected': [3463, 3505, 3537], 'intravenously': [3464], 'Evans': [3466], 'blue': [3467, 3560], 'dye': [3468, 3486], '(Sigma-Aldrich)': [3469], 'containing': [3470], '250': [3471], 'μg': [3472, 3500], '2,4-dinitropheyl-human': [3473], 'serum': [3474], 'albumin.': [3475], 'Thirty': [3476], 'minutes': [3477], 'antigen': [3480], 'challenge,': [3481], 'amounts': [3483], 'extravasated': [3485], 'measured': [3488], 'measuring': [3490], '620': [3494], 'nm.': [3495], 'some': [3497], 'experiments,': [3498], 'intradermally': [3506, 3538], 'ears': [3509, 3517, 3532], 'together': [3510], 'anti-2,4-dinitrophenyl': [3512], '(H1-ε-26).': [3514], 'fixed': [3519], '10%': [3521], 'formaldehyde': [3522], 'embedded': [3524], 'paraffin,': [3526], 'sections': [3528], 'stained.': [3530], '×': [3541], '106': [3542], '6': [3546], 'weeks': [3547], 'stained': [3557], 'toluidine': [3559], 'quantified': [3562], 'Results': [3656], 'means': [3660], '±': [3661, 3765], 'standard': [3662, 3766], 'deviation.': [3663], 'two-tailed': [3665], 'unpaired': [3666], "Student's": [3667], 't': [3668], 'test': [3669], 'compare': [3673], 'differences': [3674], 'groups.Supplementary': [3677], 'S2Surface': [3679], 'c-kit,': [3684], 'transfectants.': [3691], 'Representative': [3692], 'two': [3694], 'independent': [3695], 'experiments.': [3696], 'BMMC,': [3697, 3732], 'bone': [3698, 3733], 'cells.View': [3701, 3736], 'Large': [3702, 3737, 3779], 'ViewerDownload': [3705, 3740, 3782], 'Hi-res': [3706, 3741, 3783], 'image': [3707, 3742, 3784], 'Download': [3708, 3743, 3785], '(PPT)Supplementary': [3709, 3744], 'S3Mast': [3711], 'transplantation': [3722], '(n': [3727, 3760], '=': [3728, 3761], '3–7': [3729], 'per': [3730, 3763], 'group).': [3731], 'S4PCA': [3746], 'transplanted': [3751], 'hCD300f-WT-transduced': [3753], 'pretreated': [3756], '5': [3762], 'group,': [3764], 'deviation).': [3767], '*P': [3768], '<0.01.': [3769], 'PC,': [3770], 'phosphatidylcholine;': [3771], 'PCA,': [3772], 'anaphylaxis;': [3775], 'WT,': [3776], 'wild': [3777], 'type.View': [3778], '(PPT)': [3786]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2970913233', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 2}], 'updated_date': '2024-12-12T01:16:16.394246', 'created_date': '2019-09-05'}