Title: Boryl-Directed, Ir-Catalyzed C(sp<sup>3</sup>)–H Borylation of Alkylboronic Acids Leading to Site-Selective Synthesis of Polyborylalkanes
Abstract: Pyrazolylaniline serves as a temporary directing group attached to the boron atom of alkylboronic acids in Ir-catalyzed C(sp3)–H borylation. The reaction takes place at α-, β-, and γ-C–H bonds, giving polyborylated products including di-, tri-, tetra-, and even pentaborylalkanes. α-C–H borylation was generally found to be the preferred reaction of primary alkylboronic acid derivatives, whereas β- or γ-borylation also occurred if β- or γ-C–H bonds were located on the methyl group.
Publication Year: 2019
Publication Date: 2019-08-06
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 35
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