Title: Masked hypertension during prehypertension and anthropometric indices: Prospective study
Abstract: Analysis of the ambulatory blood pressure profile of patients with prehypertension (PHT) and the assessment of their cardiovascular risk have rarely been studied. Our work aimed to establish the link between masked hypertension (MH) and the cardiovascular risk factors (CVR) associated with prehypertension. From 2015 to 2016, a cross-sectional study was conducted in primary care consultation in Algiers on a sample of 1086 adults, without known hypertension. They were screened for PHT (defined by the JNCVII as systolic BP between 120 and 139 mmHg or diastolic BP between 80 and 89 mm Hg). Pre-hypertensive patients were assessed for their anthropometric indices (height, weight and waist circumference) and an ambulatory blood pressure measurement (ABPM). The Pearson correlation test was used to investigate the relationship between MH and the major CVR factors in these patients. Three hundred and ninety-nine pre-hypertensive patients were identified (prevalence: 36.7%), concerning more men than women (50.0 vs. 31.5%, P < 0.001). ABPM was performed in 273 patients, and MH was treated in 52.4% of cases, affecting men and women equally (P = 0.29). Nighttime MH (≥ 120/70 mmHg) was significantly more frequent than daytime MH (≥ 135/85 mmHg) (57% vs. 36%, P = 0.0005). Patients with MH were older than those with normal ABPM (46 ± 13.33 vs. 42 ± 14.36 years, P = 0.01), had higher body mass index (BMI) (29.47 ± 5.507 vs. 26.6 ± 4.985 kg/m2, P = 0.00001) and more frequent android obesity (64% vs. 43%, P = 0.0006). In MH patients, we found a positive correlation between daytime pressure and weight (r = 0.361), BMI (r = 0.283) and waist circumference (r = 0.374). This positive relationship was also valid for the night pressure values (r = 0.379, 0.399 and 0.410 respectively). Masked hypertension is a recognized source of increased CVR, thus we suggest to record and monitor the ambulatory pressure in pre-hypertensive subjects, especially as they are overweight.
Publication Year: 2019
Publication Date: 2019-08-01
Language: en
Type: article
Indexed In: ['crossref']
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