Publication Information

{'id': 'https://openalex.org/W2955881909', 'doi': 'https://doi.org/10.1158/1538-7445.am2019-4458', 'title': 'Abstract 4458: Clinical significance of <i>PIK3CA</i> and <i>ESR1</i> mutations in ctDNA and FFPE samples from the MONARCH 2 study of abemaciclib plus fulvestrant', 'display_name': 'Abstract 4458: Clinical significance of <i>PIK3CA</i> and <i>ESR1</i> mutations in ctDNA and FFPE samples from the MONARCH 2 study of abemaciclib plus fulvestrant', 'publication_year': 2019, 'publication_date': '2019-07-01', 'ids': {'openalex': 'https://openalex.org/W2955881909', 'doi': 'https://doi.org/10.1158/1538-7445.am2019-4458', 'mag': '2955881909'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.am2019-4458', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168522863', 'display_name': 'Cancer Research', 'issn_l': '0008-5472', 'issn': ['0008-5472', '1538-7445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5069056507', 'display_name': 'Sara M. Tolaney', 'orcid': 'https://orcid.org/0000-0002-5940-8671'}, 'institutions': [{'id': 'https://openalex.org/I4210117453', 'display_name': 'Dana-Farber Cancer Institute', 'ror': 'https://ror.org/02jzgtq86', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117453']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sara M. Tolaney', 'raw_affiliation_strings': ['1Dana-Farber Cancer Institute, Boston, MA;'], 'affiliations': [{'raw_affiliation_string': '1Dana-Farber Cancer Institute, Boston, MA;', 'institution_ids': ['https://openalex.org/I4210117453']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091245889', 'display_name': 'Masakazu Toi', 'orcid': 'https://orcid.org/0000-0003-1488-9958'}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Masakazu Toi', 'raw_affiliation_strings': ['2Kyoto University, Kyoto, Japan;'], 'affiliations': [{'raw_affiliation_string': '2Kyoto University, Kyoto, Japan;', 'institution_ids': ['https://openalex.org/I22299242']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007579054', 'display_name': 'Patrick Neven', 'orcid': 'https://orcid.org/0000-0002-1434-9460'}, 'institutions': [{'id': 'https://openalex.org/I2800231306', 'display_name': 'Universitair Ziekenhuis Leuven', 'ror': 'https://ror.org/0424bsv16', 'country_code': 'BE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800231306']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Patrick Neven', 'raw_affiliation_strings': ['3UZ Leuven, Leuven, Belgium;'], 'affiliations': [{'raw_affiliation_string': '3UZ Leuven, Leuven, Belgium;', 'institution_ids': ['https://openalex.org/I2800231306']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030577122', 'display_name': 'Joohyuk Sohn', 'orcid': 'https://orcid.org/0000-0002-2303-2764'}, 'institutions': [], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Joohyuk Sohn', 'raw_affiliation_strings': ['4Yonsei Cancer Center, Seoul, Republic of Korea;'], 'affiliations': [{'raw_affiliation_string': '4Yonsei Cancer Center, Seoul, Republic of Korea;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013148496', 'display_name': 'Eva‐Maria Grischke', 'orcid': 'https://orcid.org/0000-0001-7413-5053'}, 'institutions': [{'id': 'https://openalex.org/I4210122374', 'display_name': 'Universitäts Frauenklinik', 'ror': 'https://ror.org/02veq1j93', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210094118', 'https://openalex.org/I4210122374']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Eva-Maria Grischke', 'raw_affiliation_strings': ['5Universitats-Frauenklinik Tubingen, Tübingen, Germany;'], 'affiliations': [{'raw_affiliation_string': '5Universitats-Frauenklinik Tubingen, Tübingen, Germany;', 'institution_ids': ['https://openalex.org/I4210122374']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030451537', 'display_name': 'Antonio Llombart‐Cussac', 'orcid': 'https://orcid.org/0000-0003-4515-8293'}, 'institutions': [{'id': 'https://openalex.org/I4210119293', 'display_name': 'Hospital Arnau de Vilanova', 'ror': 'https://ror.org/02s7fkk92', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210119293']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Antonio Llombart-Cussac', 'raw_affiliation_strings': ['6FISABIO - Hospital Arnau Vilanova, Valencia, Spain;'], 'affiliations': [{'raw_affiliation_string': '6FISABIO - Hospital Arnau Vilanova, Valencia, Spain;', 'institution_ids': ['https://openalex.org/I4210119293']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090789911', 'display_name': 'Hatem Soliman', 'orcid': 'https://orcid.org/0000-0001-6644-2264'}, 'institutions': [{'id': 'https://openalex.org/I3019308854', 'display_name': 'Moffitt Cancer Center', 'ror': 'https://ror.org/01xf75524', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3019308854']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Hatem Soliman', 'raw_affiliation_strings': ['7H. Lee Moffitt Cancer Center, Tampa, FL;'], 'affiliations': [{'raw_affiliation_string': '7H. Lee Moffitt Cancer Center, Tampa, FL;', 'institution_ids': ['https://openalex.org/I3019308854']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081153905', 'display_name': 'Lacey M. Litchfield', 'orcid': 'https://orcid.org/0009-0004-5232-9585'}, 'institutions': [{'id': 'https://openalex.org/I168537998', 'display_name': 'Eli Lilly (United States)', 'ror': 'https://ror.org/01qat3289', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I168537998']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Lacey M. Litchfield', 'raw_affiliation_strings': ['8Eli Lilly and Company, Indianapolis, IN;'], 'affiliations': [{'raw_affiliation_string': '8Eli Lilly and Company, Indianapolis, IN;', 'institution_ids': ['https://openalex.org/I168537998']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021147423', 'display_name': 'Sameera R. Wijayawardana', 'orcid': 'https://orcid.org/0000-0002-5187-167X'}, 'institutions': [{'id': 'https://openalex.org/I168537998', 'display_name': 'Eli Lilly (United States)', 'ror': 'https://ror.org/01qat3289', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I168537998']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sameera Wijayawardana', 'raw_affiliation_strings': ['8Eli Lilly and Company, Indianapolis, IN;'], 'affiliations': [{'raw_affiliation_string': '8Eli Lilly and Company, Indianapolis, IN;', 'institution_ids': ['https://openalex.org/I168537998']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001838875', 'display_name': 'Tammy Forrester', 'orcid': 'https://orcid.org/0009-0000-4712-3225'}, 'institutions': [{'id': 'https://openalex.org/I168537998', 'display_name': 'Eli Lilly (United States)', 'ror': 'https://ror.org/01qat3289', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I168537998']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Tammy Forrester', 'raw_affiliation_strings': ['8Eli Lilly and Company, Indianapolis, IN;'], 'affiliations': [{'raw_affiliation_string': '8Eli Lilly and Company, Indianapolis, IN;', 'institution_ids': ['https://openalex.org/I168537998']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048549140', 'display_name': 'Valerie M. Jansen', 'orcid': 'https://orcid.org/0009-0002-5754-6111'}, 'institutions': [{'id': 'https://openalex.org/I168537998', 'display_name': 'Eli Lilly (United States)', 'ror': 'https://ror.org/01qat3289', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I168537998']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Valerie M. Jansen', 'raw_affiliation_strings': ['8Eli Lilly and Company, Indianapolis, IN;'], 'affiliations': [{'raw_affiliation_string': '8Eli Lilly and Company, Indianapolis, IN;', 'institution_ids': ['https://openalex.org/I168537998']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5066769011', 'display_name': 'George W. Sledge', 'orcid': 'https://orcid.org/0000-0003-0297-0775'}, 'institutions': [{'id': 'https://openalex.org/I97018004', 'display_name': 'Stanford University', 'ror': 'https://ror.org/00f54p054', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I97018004']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'George W. Sledge', 'raw_affiliation_strings': ['9Stanford University, Stanford, CA.'], 'affiliations': [{'raw_affiliation_string': '9Stanford University, Stanford, CA.', 'institution_ids': ['https://openalex.org/I97018004']}]}], 'institution_assertions': [], 'countries_distinct_count': 6, 'institutions_distinct_count': 8, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.518, 'has_fulltext': False, 'cited_by_count': 14, 'citation_normalized_percentile': {'value': 0.8743, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 88, 'max': 89}, 'biblio': {'volume': '79', 'issue': '13_Supplement', 'first_page': '4458', 'last_page': '4458'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12829', 'display_name': 'Advanced Breast Cancer Therapies', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12829', 'display_name': 'Advanced Breast Cancer Therapies', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/fulvestrant', 'display_name': 'Fulvestrant', 'score': 0.8420087}, {'id': 'https://openalex.org/keywords/concordance', 'display_name': 'Concordance', 'score': 0.80282784}, {'id': 'https://openalex.org/keywords/cold-pcr', 'display_name': 'COLD-PCR', 'score': 0.44547442}, {'id': 'https://openalex.org/keywords/veliparib', 'display_name': 'Veliparib', 'score': 0.4232145}], 'concepts': [{'id': 'https://openalex.org/C2780482068', 'wikidata': 'https://www.wikidata.org/wiki/Q5508491', 'display_name': 'Fulvestrant', 'level': 5, 'score': 0.8420087}, {'id': 'https://openalex.org/C160798450', 'wikidata': 'https://www.wikidata.org/wiki/Q4230870', 'display_name': 'Concordance', 'level': 2, 'score': 0.80282784}, {'id': 'https://openalex.org/C50524450', 'wikidata': 'https://www.wikidata.org/wiki/Q5013338', 'display_name': 'COLD-PCR', 'level': 5, 'score': 0.44547442}, {'id': 'https://openalex.org/C501734568', 'wikidata': 'https://www.wikidata.org/wiki/Q42918', 'display_name': 'Mutation', 'level': 3, 'score': 0.4364766}, {'id': 'https://openalex.org/C530470458', 'wikidata': 'https://www.wikidata.org/wiki/Q128581', 'display_name': 'Breast cancer', 'level': 3, 'score': 0.42613876}, {'id': 'https://openalex.org/C2781312401', 'wikidata': 'https://www.wikidata.org/wiki/Q7919041', 'display_name': 'Veliparib', 'level': 5, 'score': 0.4232145}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.40586838}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.3927976}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.38954678}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.38801187}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.32923883}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.32546633}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.30074984}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.2491481}, {'id': 'https://openalex.org/C84606932', 'wikidata': 'https://www.wikidata.org/wiki/Q416496', 'display_name': 'Estrogen receptor', 'level': 4, 'score': 0.1820209}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.18163547}, {'id': 'https://openalex.org/C176944494', 'wikidata': 'https://www.wikidata.org/wiki/Q1415380', 'display_name': 'Point mutation', 'level': 4, 'score': 0.13488281}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.13236311}, {'id': 'https://openalex.org/C82381507', 'wikidata': 'https://www.wikidata.org/wiki/Q416878', 'display_name': 'Polymerase', 'level': 3, 'score': 0.12646213}, {'id': 'https://openalex.org/C182979987', 'wikidata': 'https://www.wikidata.org/wiki/Q3907241', 'display_name': 'Poly ADP ribose polymerase', 'level': 4, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.am2019-4458', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168522863', 'display_name': 'Cancer Research', 'issn_l': '0008-5472', 'issn': ['0008-5472', '1538-7445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.79, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4387909540', 'https://openalex.org/W4361915263', 'https://openalex.org/W4361884634', 'https://openalex.org/W2971197283', 'https://openalex.org/W2599182281', 'https://openalex.org/W2165616575', 'https://openalex.org/W2056214045', 'https://openalex.org/W1991229228', 'https://openalex.org/W1982853714', 'https://openalex.org/W1601684588'], 'abstract_inverted_index': {'Abstract': [0], 'BACKGROUND:': [1], 'Mutations': [2], 'in': [3, 10, 15, 65, 116, 147, 158, 189, 203, 210, 222, 228, 255, 263, 267, 289, 294, 399], 'PIK3CA': [4, 27, 83, 112, 145, 223, 243, 259, 298, 395], 'and': [5, 28, 33, 43, 54, 88, 123, 140, 149, 165, 182, 191, 205, 224, 232, 244, 248, 260, 396, 401], 'ESR1': [6, 29, 89, 154, 187, 201, 225, 245, 261, 300, 397], 'have': [7], 'been': [8], 'implicated': [9], 'resistance': [11], 'to': [12, 274, 287], 'endocrine': [13], 'therapy': [14, 252], 'HR+': [16], 'metastatic': [17], 'breast': [18], 'cancer.': [19], 'Herein,': [20], 'we': [21, 238], 'assessed': [22], 'the': [23, 132, 174, 213, 216, 240, 277, 303, 405, 417], 'clinical': [24], 'significance': [25, 393], 'of': [26, 82, 119, 126, 144, 161, 168, 186, 198, 200, 215, 242, 280, 285, 297, 305, 394, 409, 416], 'mutations': [30, 81, 113, 146, 155, 188, 202, 262, 398], 'from': [31, 36, 61, 109, 250, 404], 'ctDNA': [32, 148, 190, 204, 264, 281, 400], 'FFPE': [34, 55, 128, 150, 170, 192, 206, 235, 269, 402], 'samples': [35, 50, 57, 122, 151, 164, 193, 207, 270, 403], 'patients': [37, 63, 311], 'treated': [38], 'with': [39, 272, 312], 'abemaciclib': [40, 251, 286, 410], 'plus': [41, 45, 411], 'fulvestrant': [42, 288, 412], 'placebo': [44], 'fulvestrant.': [46], 'METHODS:': [47], 'Baseline': [48], 'plasma': [49, 121, 163, 231], '(n': [51, 58], '=': [52, 59], '334)': [53], 'tumor': [56], '434)': [60], '669': [62], 'enrolled': [64], 'MONARCH': [66, 290, 406], '2': [67, 291, 407], 'were': [68, 107, 114, 156, 226], 'analyzed.': [69], 'Extracted': [70], 'DNA': [71, 97], 'was': [72, 131, 152, 173, 194, 307], 'analyzed': [73], 'by': [74, 137, 179, 212], 'droplet': [75], 'digital': [76], 'PCR': [77], 'for': [78, 310, 420], 'four': [79], 'hotspot': [80], '(E542K;': [84], 'E545K;': [85], 'H1047L;': [86], 'H1047R)': [87], '(D538G;': [90], 'Y537C;': [91], 'Y537N;': [92], 'Y537S).': [93], 'Samples': [94], 'that': [95], 'failed': [96], 'QC': [98], 'or': [99, 299], 'where': [100], 'mutation': [101, 135, 177, 246], 'status': [102, 247], 'could': [103], 'not': [104, 266], 'be': [105], 'determined': [106], 'excluded': [108], 'analysis.': [110, 282], 'RESULTS:': [111], 'detected': [115, 157], '96': [117], '(40.3%)': [118], '238': [120], '133': [124], '(39.9%)': [125], '333': [127], 'samples.': [129, 171, 236], 'H1047R': [130], 'most': [133, 175], 'frequent': [134, 176], 'followed': [136, 178], 'E545K,': [138], 'E542K,': [139], 'H1047L.': [141], 'The': [142, 184, 283], 'concordance': [143, 185], '62.8%.': [153], '190': [159], '(64.4%)': [160], '295': [162], '15': [166], '(4.4%)': [167], '344': [169], 'D538G': [172], 'Y537C,': [180], 'Y537N,': [181], 'Y537S.': [183], '37.1%;': [195], 'this': [196], 'rate': [197], 'detection': [199], 'is': [208], 'explained': [209], 'part': [211], 'site': [214], 'biopsy': [217], '(primary': [218], 'vs': [219], 'metastatic).': [220], 'Co-mutations': [221], 'observed': [227], '86': [229], '(36.1%)': [230], '5': [233], '(1.5%)': [234], 'Finally,': [237], 'examined': [239], 'relationship': [241], 'benefit': [249, 306], 'as': [253], 'shown': [254], 'Table': [256, 317], '1.': [257], 'CONCLUSIONS:': [258], 'but': [265], 'archived': [268], 'correlated': [271], 'response': [273], 'abemaciclib,': [275], 'confirming': [276], 'potential': [278], 'use': [279], 'addition': [284], 'demonstrated': [292], 'improvement': [293], 'PFS': [295, 325, 328], 'regardless': [296], 'status;': [301], 'however,': [302], 'magnitude': [304], 'numerically': [308], 'greater': [309], 'tumors': [313], 'harboring': [314], 'PIK3CA/ESR1': [315], 'mutations.': [316], '1.Abemaciclib': [318], '+': [319, 321], 'FulvestrantPlacebo': [320], 'FulvestrantMutation': [322], 'Status': [323], '(Plasma)nMedian': [324], '(95%': [326, 329, 332], 'CI)nMedian': [327], 'CI)Hazard': [330], 'Ratio': [331], 'CI)PIK3CA': [333], 'wild-type9120': [334], '(14,': [335], 'NA)5112.7': [336], '(7.9,': [337], 'NA)0.68': [338], '(0.42,': [339], '1.09)PIK3CA': [340], 'mutant5815': [341], '(9.4,': [342], 'NA)385.7': [343], '(3.8,': [344], '15)0.46': [345], '(0.27,': [346], '0.78)ESR1': [347], 'wild-type7216.3': [348], '(12.4,': [349], '22.8)3311.6': [350], '(7.4,': [351], '23.1)0.69': [352], '(0.41,': [353], '1.18)ESR1': [354], 'mutant11821.9': [355], '(15,': [356], 'NA)7210.3': [357], '(5.7,': [358], '15.6)0.49': [359], '(0.33,': [360], '0.73)': [361], 'Citation': [362], 'Format:': [363], 'Sara': [364], 'M.': [365, 380, 387], 'Tolaney,': [366], 'Masakazu': [367], 'Toi,': [368], 'Patrick': [369], 'Neven,': [370], 'Joohyuk': [371], 'Sohn,': [372], 'Eva-Maria': [373], 'Grischke,': [374], 'Antonio': [375], 'Llombart-Cussac,': [376], 'Hatem': [377], 'Soliman,': [378], 'Lacey': [379], 'Litchfield,': [381], 'Sameera': [382], 'Wijayawardana,': [383], 'Tammy': [384], 'Forrester,': [385], 'Valerie': [386], 'Jansen,': [388], 'George': [389], 'W.': [390], 'Sledge.': [391], 'Clinical': [392], 'study': [408], '[abstract].': [413], 'In:': [414], 'Proceedings': [415], 'American': [418], 'Association': [419], 'Cancer': [421, 435], 'Research': [422], 'Annual': [423], 'Meeting': [424], '2019;': [425], '2019': [426], 'Mar': [427], '29-Apr': [428], '3;': [429], 'Atlanta,': [430], 'GA.': [431], 'Philadelphia': [432], '(PA):': [433], 'AACR;': [434], 'Res': [436], '2019;79(13': [437], 'Suppl):Abstract': [438], 'nr': [439], '4458.': [440]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2955881909', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 5}, {'year': 2019, 'cited_by_count': 1}], 'updated_date': '2025-01-10T22:43:40.274029', 'created_date': '2019-07-12'}