Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2955816942', 'doi': 'https://doi.org/10.1039/c9mt00102f', 'title': 'Integrity of zinc finger motifs in PML protein is necessary for inducing its degradation by antimony', 'display_name': 'Integrity of zinc finger motifs in PML protein is necessary for inducing its degradation by antimony', 'publication_year': 2019, 'publication_date': '2019-07-05', 'ids': {'openalex': 'https://openalex.org/W2955816942', 'doi': 'https://doi.org/10.1039/c9mt00102f', 'mag': '2955816942', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/31313788'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1039/c9mt00102f', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S134674912', 'display_name': 'Metallomics', 'issn_l': '1756-5901', 'issn': ['1756-5901', '1756-591X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5101867463', 'display_name': 'Chang Yang', 'orcid': 'https://orcid.org/0000-0002-7006-6377'}, 'institutions': [{'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}, {'id': 'https://openalex.org/I38260057', 'display_name': 'In-Q-Tel', 'ror': 'https://ror.org/02qp5k481', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I38260057']}], 'countries': ['CN', 'US'], 'is_corresponding': False, 'raw_author_name': 'Chang Yang', 'raw_affiliation_strings': ['Department of Pharmacology, School of Medicine, Zhejiang University, China', 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Zhejiang, 310058, China. Fax: +(86)-571-8820-6736; Tel: +(86)-571-8820-6736', 'Tel: +(86)-571-8820-6736'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, School of Medicine, Zhejiang University, China', 'institution_ids': ['https://openalex.org/I76130692']}, {'raw_affiliation_string': 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Zhejiang, 310058, China. Fax: +(86)-571-8820-6736; Tel: +(86)-571-8820-6736', 'institution_ids': ['https://openalex.org/I76130692']}, {'raw_affiliation_string': 'Tel: +(86)-571-8820-6736', 'institution_ids': ['https://openalex.org/I38260057']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5058066453', 'display_name': 'Rui Hao', 'orcid': 'https://orcid.org/0000-0003-0031-8185'}, 'institutions': [{'id': 'https://openalex.org/I44673925', 'display_name': 'Inner Mongolia Medical University', 'ror': 'https://ror.org/01mtxmr84', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I44673925']}, {'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Rui Hao', 'raw_affiliation_strings': ['College of Pharmaceutical Sciences, Inner Mongolia Medical University, Hohhot, China', 'Department of Pharmacology, School of Medicine, Zhejiang University, China'], 'affiliations': [{'raw_affiliation_string': 'College of Pharmaceutical Sciences, Inner Mongolia Medical University, Hohhot, China', 'institution_ids': ['https://openalex.org/I44673925']}, {'raw_affiliation_string': 'Department of Pharmacology, School of Medicine, Zhejiang University, China', 'institution_ids': ['https://openalex.org/I76130692']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108564256', 'display_name': 'Yong Lan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yong Fei Lan', 'raw_affiliation_strings': ['College of Pharmaceutical Sciences, Zhejiang University, China'], 'affiliations': [{'raw_affiliation_string': 'College of Pharmaceutical Sciences, Zhejiang University, China', 'institution_ids': ['https://openalex.org/I76130692']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5024918242', 'display_name': 'Ye Jia Chen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}, {'id': 'https://openalex.org/I38260057', 'display_name': 'In-Q-Tel', 'ror': 'https://ror.org/02qp5k481', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I38260057']}], 'countries': ['CN', 'US'], 'is_corresponding': False, 'raw_author_name': 'Ye Jia Chen', 'raw_affiliation_strings': ['Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Zhejiang, 310058, China. Fax: +(86)-571-8820-6736; Tel: +(86)-571-8820-6736', 'Tel: +(86)-571-8820-6736'], 'affiliations': [{'raw_affiliation_string': 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Zhejiang, 310058, China. Fax: +(86)-571-8820-6736; Tel: +(86)-571-8820-6736', 'institution_ids': ['https://openalex.org/I76130692']}, {'raw_affiliation_string': 'Tel: +(86)-571-8820-6736', 'institution_ids': ['https://openalex.org/I38260057']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100406923', 'display_name': 'Chao Wang', 'orcid': 'https://orcid.org/0000-0002-0216-2965'}, 'institutions': [{'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}, {'id': 'https://openalex.org/I38260057', 'display_name': 'In-Q-Tel', 'ror': 'https://ror.org/02qp5k481', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I38260057']}], 'countries': ['CN', 'US'], 'is_corresponding': False, 'raw_author_name': 'Chao Wang', 'raw_affiliation_strings': ['Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Zhejiang, 310058, China. Fax: +(86)-571-8820-6736; Tel: +(86)-571-8820-6736', 'Tel: +(86)-571-8820-6736'], 'affiliations': [{'raw_affiliation_string': 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Zhejiang, 310058, China. Fax: +(86)-571-8820-6736; Tel: +(86)-571-8820-6736', 'institution_ids': ['https://openalex.org/I76130692']}, {'raw_affiliation_string': 'Tel: +(86)-571-8820-6736', 'institution_ids': ['https://openalex.org/I38260057']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055273232', 'display_name': 'Na Bu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210137217', 'display_name': "Women's Hospital, School of Medicine, Zhejiang University", 'ror': 'https://ror.org/042t7yh44', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210137217']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Na Bu', 'raw_affiliation_strings': ["Department of Pharmacy, Women's Hospital, School of Medicine, Zhejiang University, China"], 'affiliations': [{'raw_affiliation_string': "Department of Pharmacy, Women's Hospital, School of Medicine, Zhejiang University, China", 'institution_ids': ['https://openalex.org/I4210137217']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083735838', 'display_name': 'Qian Qian Wang', 'orcid': 'https://orcid.org/0000-0001-5084-3450'}, 'institutions': [{'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}, {'id': 'https://openalex.org/I38260057', 'display_name': 'In-Q-Tel', 'ror': 'https://ror.org/02qp5k481', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I38260057']}], 'countries': ['CN', 'US'], 'is_corresponding': False, 'raw_author_name': 'Qian Qian Wang', 'raw_affiliation_strings': ['College of Pharmaceutical Sciences, Zhejiang University, China', 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Zhejiang, 310058, China. Fax: +(86)-571-8820-6736; Tel: +(86)-571-8820-6736', 'Tel: +(86)-571-8820-6736'], 'affiliations': [{'raw_affiliation_string': 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Zhejiang, 310058, China. Fax: +(86)-571-8820-6736; Tel: +(86)-571-8820-6736', 'institution_ids': ['https://openalex.org/I76130692']}, {'raw_affiliation_string': 'College of Pharmaceutical Sciences, Zhejiang University, China', 'institution_ids': ['https://openalex.org/I76130692']}, {'raw_affiliation_string': 'Tel: +(86)-571-8820-6736', 'institution_ids': ['https://openalex.org/I38260057']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049370838', 'display_name': 'Liaqat Hussain', 'orcid': 'https://orcid.org/0000-0001-7171-5917'}, 'institutions': [{'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}, {'id': 'https://openalex.org/I38260057', 'display_name': 'In-Q-Tel', 'ror': 'https://ror.org/02qp5k481', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I38260057']}], 'countries': ['CN', 'US'], 'is_corresponding': False, 'raw_author_name': 'Liaqat Hussain', 'raw_affiliation_strings': ['Department of Pharmacology, School of Medicine, Zhejiang University, China', 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Zhejiang, 310058, China. Fax: +(86)-571-8820-6736; Tel: +(86)-571-8820-6736', 'Tel: +(86)-571-8820-6736'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, School of Medicine, Zhejiang University, China', 'institution_ids': ['https://openalex.org/I76130692']}, {'raw_affiliation_string': 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Zhejiang, 310058, China. Fax: +(86)-571-8820-6736; Tel: +(86)-571-8820-6736', 'institution_ids': ['https://openalex.org/I76130692']}, {'raw_affiliation_string': 'Tel: +(86)-571-8820-6736', 'institution_ids': ['https://openalex.org/I38260057']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100343645', 'display_name': 'Ya Li', 'orcid': 'https://orcid.org/0000-0001-7246-2069'}, 'institutions': [{'id': 'https://openalex.org/I4210166576', 'display_name': 'First Affiliated Hospital Zhejiang University', 'ror': 'https://ror.org/05m1p5x56', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210166576']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Li Ya Ma', 'raw_affiliation_strings': ['Department of Hematology, The First Affiliated Hospital, Zhejiang University, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Hematology, The First Affiliated Hospital, Zhejiang University, China', 'institution_ids': ['https://openalex.org/I4210166576']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063622346', 'display_name': 'Yasen Maimaitiyiming', 'orcid': 'https://orcid.org/0000-0002-1990-4857'}, 'institutions': [{'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}, {'id': 'https://openalex.org/I38260057', 'display_name': 'In-Q-Tel', 'ror': 'https://ror.org/02qp5k481', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I38260057']}], 'countries': ['CN', 'US'], 'is_corresponding': False, 'raw_author_name': 'Yasen Maimaitiyiming', 'raw_affiliation_strings': ['Department of Pharmacology, School of Medicine, Zhejiang University, China', 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Zhejiang, 310058, China. Fax: +(86)-571-8820-6736; Tel: +(86)-571-8820-6736', 'Tel: +(86)-571-8820-6736'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, School of Medicine, Zhejiang University, China', 'institution_ids': ['https://openalex.org/I76130692']}, {'raw_affiliation_string': 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Zhejiang, 310058, China. Fax: +(86)-571-8820-6736; Tel: +(86)-571-8820-6736', 'institution_ids': ['https://openalex.org/I76130692']}, {'raw_affiliation_string': 'Tel: +(86)-571-8820-6736', 'institution_ids': ['https://openalex.org/I38260057']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069860284', 'display_name': 'Xiao Yang Lu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210166576', 'display_name': 'First Affiliated Hospital Zhejiang University', 'ror': 'https://ror.org/05m1p5x56', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210166576']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiao Yang Lu', 'raw_affiliation_strings': ['Department of Pharmacy, The First Affiliated Hospital, Zhejiang University, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacy, The First Affiliated Hospital, Zhejiang University, China', 'institution_ids': ['https://openalex.org/I4210166576']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5015235822', 'display_name': 'Hua Naranmandura', 'orcid': 'https://orcid.org/0000-0003-0799-2340'}, 'institutions': [{'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}, {'id': 'https://openalex.org/I44673925', 'display_name': 'Inner Mongolia Medical University', 'ror': 'https://ror.org/01mtxmr84', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I44673925']}, {'id': 'https://openalex.org/I4210166576', 'display_name': 'First Affiliated Hospital Zhejiang University', 'ror': 'https://ror.org/05m1p5x56', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210166576']}, {'id': 'https://openalex.org/I38260057', 'display_name': 'In-Q-Tel', 'ror': 'https://ror.org/02qp5k481', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I38260057']}], 'countries': ['CN', 'US'], 'is_corresponding': False, 'raw_author_name': 'Hua Naranmandura', 'raw_affiliation_strings': ['College of Pharmaceutical Sciences, Inner Mongolia Medical University, Hohhot, China', 'Department of Hematology, The First Affiliated Hospital, Zhejiang University, China', 'Department of Pharmacology, School of Medicine, Zhejiang University, China', 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Zhejiang, 310058, China. Fax: +(86)-571-8820-6736; Tel: +(86)-571-8820-6736', 'Tel: +(86)-571-8820-6736'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, School of Medicine, Zhejiang University, China', 'institution_ids': ['https://openalex.org/I76130692']}, {'raw_affiliation_string': 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Zhejiang, 310058, China. Fax: +(86)-571-8820-6736; Tel: +(86)-571-8820-6736', 'institution_ids': ['https://openalex.org/I76130692']}, {'raw_affiliation_string': 'College of Pharmaceutical Sciences, Inner Mongolia Medical University, Hohhot, China', 'institution_ids': ['https://openalex.org/I44673925']}, {'raw_affiliation_string': 'Department of Hematology, The First Affiliated Hospital, Zhejiang University, China', 'institution_ids': ['https://openalex.org/I4210166576']}, {'raw_affiliation_string': 'Tel: +(86)-571-8820-6736', 'institution_ids': ['https://openalex.org/I38260057']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2319, 'currency': 'USD', 'value_usd': 2319, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.575, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 8, 'citation_normalized_percentile': {'value': 0.622287, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 83, 'max': 84}, 'biblio': {'volume': '11', 'issue': '8', 'first_page': '1419', 'last_page': '1429'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11559', 'display_name': 'Retinoids in leukemia and cellular processes', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11559', 'display_name': 'Retinoids in leukemia and cellular processes', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10309', 'display_name': 'Acute Myeloid Leukemia Research', 'score': 0.9976, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10570', 'display_name': 'Drug Transport and Resistance Mechanisms', 'score': 0.9867, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/arsenic-trioxide', 'display_name': 'Arsenic Trioxide', 'score': 0.869556}, {'id': 'https://openalex.org/keywords/promyelocytic-leukemia-protein', 'display_name': 'Promyelocytic leukemia protein', 'score': 0.5580041}, {'id': 'https://openalex.org/keywords/antimony-trioxide', 'display_name': 'Antimony trioxide', 'score': 0.53322846}, {'id': 'https://openalex.org/keywords/protein-degradation', 'display_name': 'Protein Degradation', 'score': 0.43317273}], 'concepts': [{'id': 'https://openalex.org/C2780386689', 'wikidata': 'https://www.wikidata.org/wiki/Q7739', 'display_name': 'Arsenic trioxide', 'level': 3, 'score': 0.869556}, {'id': 'https://openalex.org/C541565711', 'wikidata': 'https://www.wikidata.org/wiki/Q1099', 'display_name': 'Antimony', 'level': 2, 'score': 0.76166403}, {'id': 'https://openalex.org/C24284526', 'wikidata': 'https://www.wikidata.org/wiki/Q204785', 'display_name': 'Zinc finger', 'level': 4, 'score': 0.7560673}, {'id': 'https://openalex.org/C502230775', 'wikidata': 'https://www.wikidata.org/wiki/Q871', 'display_name': 'Arsenic', 'level': 2, 'score': 0.66707456}, {'id': 'https://openalex.org/C535196362', 'wikidata': 'https://www.wikidata.org/wiki/Q758', 'display_name': 'Zinc', 'level': 2, 'score': 0.61881983}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.61154914}, {'id': 'https://openalex.org/C2776601000', 'wikidata': 'https://www.wikidata.org/wiki/Q612108', 'display_name': 'Acute promyelocytic leukemia', 'level': 4, 'score': 0.57050544}, {'id': 'https://openalex.org/C111441629', 'wikidata': 'https://www.wikidata.org/wiki/Q18030615', 'display_name': 'Promyelocytic leukemia protein', 'level': 5, 'score': 0.5580041}, {'id': 'https://openalex.org/C2779730802', 'wikidata': 'https://www.wikidata.org/wiki/Q409035', 'display_name': 'Antimony trioxide', 'level': 3, 'score': 0.53322846}, {'id': 'https://openalex.org/C123894998', 'wikidata': 'https://www.wikidata.org/wiki/Q425158', 'display_name': 'Fusion protein', 'level': 4, 'score': 0.50382227}, {'id': 'https://openalex.org/C2992195973', 'wikidata': 'https://www.wikidata.org/wiki/Q33123', 'display_name': 'Protein degradation', 'level': 2, 'score': 0.43317273}, {'id': 'https://openalex.org/C143065580', 'wikidata': 'https://www.wikidata.org/wiki/Q3285695', 'display_name': 'Mutant', 'level': 3, 'score': 0.4196942}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.36720955}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.3437745}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.24584752}, {'id': 'https://openalex.org/C2781121885', 'wikidata': 'https://www.wikidata.org/wiki/Q425517', 'display_name': 'Retinoic acid', 'level': 3, 'score': 0.14006928}, {'id': 'https://openalex.org/C179104552', 'wikidata': 'https://www.wikidata.org/wiki/Q11165', 'display_name': 'Inorganic chemistry', 'level': 1, 'score': 0.1225411}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.109986454}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C205474432', 'wikidata': 'https://www.wikidata.org/wiki/Q1354051', 'display_name': 'Fire retardant', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C40767141', 'wikidata': 'https://www.wikidata.org/wiki/Q285697', 'display_name': 'Recombinant DNA', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000965', 'descriptor_name': 'Antimony', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D015514', 'descriptor_name': 'Oncogene Proteins, Fusion', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000071156', 'descriptor_name': 'Promyelocytic Leukemia Protein', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D059748', 'descriptor_name': 'Proteolysis', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D016335', 'descriptor_name': 'Zinc Fingers', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D000965', 'descriptor_name': 'Antimony', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002470', 'descriptor_name': 'Cell Survival', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002470', 'descriptor_name': 'Cell Survival', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015473', 'descriptor_name': 'Leukemia, Promyelocytic, Acute', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015473', 'descriptor_name': 'Leukemia, Promyelocytic, Acute', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D015473', 'descriptor_name': 'Leukemia, Promyelocytic, Acute', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D015514', 'descriptor_name': 'Oncogene Proteins, Fusion', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D015514', 'descriptor_name': 'Oncogene Proteins, Fusion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000071156', 'descriptor_name': 'Promyelocytic Leukemia Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000071156', 'descriptor_name': 'Promyelocytic Leukemia Protein', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D059748', 'descriptor_name': 'Proteolysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016335', 'descriptor_name': 'Zinc Fingers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1039/c9mt00102f', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S134674912', 'display_name': 'Metallomics', 'issn_l': '1756-5901', 'issn': ['1756-5901', '1756-591X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/31313788', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.55, 'id': 'https://metadata.un.org/sdg/6', 'display_name': 'Clean water and sanitation'}], 'grants': [{'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81603125'}, {'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81673521'}, {'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81872942'}, {'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81600139'}, {'funder': 'https://openalex.org/F4320321540', 'funder_display_name': "Ministry of Science and Technology of the People's Republic of China", 'award_id': '2018ZX10302-206'}], 'datasets': [], 'versions': [], 'referenced_works_count': 39, 'referenced_works': ['https://openalex.org/W1158911408', 'https://openalex.org/W1856932102', 'https://openalex.org/W1985468208', 'https://openalex.org/W1994453256', 'https://openalex.org/W1994683933', 'https://openalex.org/W2005449426', 'https://openalex.org/W2006382144', 'https://openalex.org/W2008573339', 'https://openalex.org/W2008789612', 'https://openalex.org/W2013131528', 'https://openalex.org/W2017653822', 'https://openalex.org/W2037632266', 'https://openalex.org/W2045978319', 'https://openalex.org/W2047008143', 'https://openalex.org/W2052246089', 'https://openalex.org/W2060552146', 'https://openalex.org/W2065349703', 'https://openalex.org/W2066402057', 'https://openalex.org/W2068249094', 'https://openalex.org/W2072188535', 'https://openalex.org/W2077872976', 'https://openalex.org/W2088497972', 'https://openalex.org/W2099376629', 'https://openalex.org/W2111279921', 'https://openalex.org/W2120343885', 'https://openalex.org/W2146186488', 'https://openalex.org/W2158958901', 'https://openalex.org/W2170325085', 'https://openalex.org/W2170332354', 'https://openalex.org/W2512140590', 'https://openalex.org/W2580224574', 'https://openalex.org/W2587518328', 'https://openalex.org/W2755522668', 'https://openalex.org/W2768202893', 'https://openalex.org/W2777159454', 'https://openalex.org/W2801881506', 'https://openalex.org/W2803060244', 'https://openalex.org/W630782363', 'https://openalex.org/W84243108'], 'related_works': ['https://openalex.org/W4388452973', 'https://openalex.org/W4254914387', 'https://openalex.org/W4243986196', 'https://openalex.org/W33403106', 'https://openalex.org/W3143468013', 'https://openalex.org/W3126933831', 'https://openalex.org/W2606399737', 'https://openalex.org/W2089470325', 'https://openalex.org/W2018374421', 'https://openalex.org/W2010216204'], 'abstract_inverted_index': {'Antimony': [0], '(Sb)': [1], 'belongs': [2], 'to': [3, 75, 94, 155, 188], 'the': [4, 11, 31, 36, 64, 113, 129, 162, 194], 'same': [5, 195], 'group': [6], 'as': [7, 197], 'arsenic': [8, 27, 90], '(As)': [9], 'in': [10, 70, 99, 119, 193], 'periodic': [12], 'table,': [13], 'and': [14, 43, 56, 89, 134, 148, 152], 'both': [15], 'share': [16], 'similar': [17, 154], 'characteristics.': [18], 'However,': [19], 'Sb2O3': [20], '(SbIII)': [21], 'has': [22], 'no': [23], 'methylation': [24], 'capacity,': [25], 'unlike': [26], 'trioxide': [28], '(As2O3).': [29], 'In': [30, 157, 175], 'present': [32], 'study,': [33], 'we': [34, 137, 159], 'determined': [35], 'effect': [37], 'of': [38, 54, 108, 115], 'SbIII': [39, 140, 181], 'on': [40], 'NB4': [41, 57, 100], 'cells': [42, 101], 'found': [44, 138, 160], 'that': [45, 112, 139, 161, 180], 'antimony': [46, 88, 133, 164], 'could': [47, 141, 169], 'induce': [48, 143, 170], 'PML-RARα': [49, 84, 96, 120], 'fusion': [50, 97, 121], 'protein': [51, 72, 85, 98, 122, 173], 'degradation,': [52, 153], 'reorganization': [53], 'PML-NBs,': [55], 'cell': [58], 'differentiation': [59], 'with': [60, 104], 'low': [61], 'cytotoxicity.': [62], 'On': [63], 'other': [65], 'hand,': [66], 'zinc': [67, 109, 116], 'finger': [68, 117], 'motifs': [69, 118], 'PML': [71, 145, 172], 'are': [73], 'considered': [74], 'be': [76, 184], 'a': [77, 124, 185], 'key': [78], 'target': [79], 'binding': [80], 'site': [81], 'for': [82, 127], 'arsenic-induced': [83], 'degradation.': [86, 174], 'Interestingly,': [87], 'lost': [91], 'their': [92], 'ability': [93], 'degrade': [95], 'following': [102], 'pretreatment': [103], 'phenanthroline': [105], '(i.e.,': [106], 'chelator': [107], 'ions),': [110], 'indicating': [111], 'integrity': [114], 'is': [123], 'fundamental': [125], 'condition': [126], 'inducing': [128], "protein's": [130], 'degradation': [131], 'by': [132], 'arsenic.': [135], 'Moreover,': [136], 'not': [142], 'mutant': [144, 171], '(e.g.,': [146], 'A126V': [147], 'L218P)': [149], 'solubility': [150], 'change': [151], 'As2O3.': [156, 198], 'contrast,': [158], 'organic': [163], 'compound': [165], 'phenylstibine': [166], 'oxide': [167], '(PSO)': [168], 'conclusion,': [176], 'our': [177], 'results': [178], 'indicate': [179], 'might': [182], 'also': [183], 'promising': [186], 'agent': [187], 'treat': [189], 'acute': [190], 'promyelocytic': [191], 'leukemia,': [192], 'manner': [196]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2955816942', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 1}], 'updated_date': '2025-01-12T14:12:33.540644', 'created_date': '2019-07-12'}