Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2953727082', 'doi': 'https://doi.org/10.1111/gtc.12709', 'title': 'A role for epigenetic adaption in evolution', 'display_name': 'A role for epigenetic adaption in evolution', 'publication_year': 2019, 'publication_date': '2019-07-04', 'ids': {'openalex': 'https://openalex.org/W2953727082', 'doi': 'https://doi.org/10.1111/gtc.12709', 'mag': '2953727082', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/31273901', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6852114'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/gtc.12709', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/gtc.12709', 'source': {'id': 'https://openalex.org/S48908450', 'display_name': 'Genes to Cells', 'issn_l': '1356-9597', 'issn': ['1356-9597', '1365-2443'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/gtc.12709', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5053494748', 'display_name': 'Ichiro Yahara', 'orcid': 'https://orcid.org/0000-0002-5863-5768'}, 'institutions': [{'id': 'https://openalex.org/I4210098918', 'display_name': 'Tokyo Metropolitan Institute of Medical Science', 'ror': 'https://ror.org/00vya8493', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I4210098918']}], 'countries': ['JP'], 'is_corresponding': True, 'raw_author_name': 'Ichiro Yahara', 'raw_affiliation_strings': ['Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan'], 'affiliations': [{'raw_affiliation_string': 'Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan', 'institution_ids': ['https://openalex.org/I4210098918']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5053494748'], 'corresponding_institution_ids': ['https://openalex.org/I4210098918'], 'apc_list': {'value': 3800, 'currency': 'USD', 'value_usd': 3800, 'provenance': 'doaj'}, 'apc_paid': {'value': 3800, 'currency': 'USD', 'value_usd': 3800, 'provenance': 'doaj'}, 'fwci': 0.052, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 3, 'citation_normalized_percentile': {'value': 0.160335, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 74, 'max': 77}, 'biblio': {'volume': '24', 'issue': '8', 'first_page': '524', 'last_page': '533'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetics and DNA Methylation', 'score': 0.9963, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetics and DNA Methylation', 'score': 0.9963, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10676', 'display_name': 'Genetics, Aging, and Longevity in Model Organisms', 'score': 0.9928, 'subfield': {'id': 'https://openalex.org/subfields/1302', 'display_name': 'Aging'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12835', 'display_name': 'FOXO transcription factor regulation', 'score': 0.9843, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C41091548', 'wikidata': 'https://www.wikidata.org/wiki/Q26939', 'display_name': 'Epigenetics', 'level': 3, 'score': 0.9470678}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.9075949}, {'id': 'https://openalex.org/C127716648', 'wikidata': 'https://www.wikidata.org/wiki/Q104053', 'display_name': 'Phenotype', 'level': 3, 'score': 0.8836179}, {'id': 'https://openalex.org/C180754005', 'wikidata': 'https://www.wikidata.org/wiki/Q80726', 'display_name': 'Allele', 'level': 3, 'score': 0.8042866}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.68454933}, {'id': 'https://openalex.org/C112672928', 'wikidata': 'https://www.wikidata.org/wiki/Q239526', 'display_name': 'Offspring', 'level': 3, 'score': 0.67496777}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.4717318}, {'id': 'https://openalex.org/C78458016', 'wikidata': 'https://www.wikidata.org/wiki/Q840400', 'display_name': 'Evolutionary biology', 'level': 1, 'score': 0.3778491}, {'id': 'https://openalex.org/C2779234561', 'wikidata': 'https://www.wikidata.org/wiki/Q11995', 'display_name': 'Pregnancy', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000220', 'descriptor_name': 'Adaptation, Biological', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000483', 'descriptor_name': 'Alleles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005075', 'descriptor_name': 'Biological Evolution', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002843', 'descriptor_name': 'Chromatin', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D044127', 'descriptor_name': 'Epigenesis, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018841', 'descriptor_name': 'HSP90 Heat-Shock Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D040582', 'descriptor_name': 'Inheritance Patterns', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008957', 'descriptor_name': 'Models, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010641', 'descriptor_name': 'Phenotype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012641', 'descriptor_name': 'Selection, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013312', 'descriptor_name': 'Stress, Physiological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/gtc.12709', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/gtc.12709', 'source': {'id': 'https://openalex.org/S48908450', 'display_name': 'Genes to Cells', 'issn_l': '1356-9597', 'issn': ['1356-9597', '1365-2443'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc6852114', 'pdf_url': 'https://europepmc.org/articles/pmc6852114?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852114', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/31273901', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/gtc.12709', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/gtc.12709', 'source': {'id': 'https://openalex.org/S48908450', 'display_name': 'Genes to Cells', 'issn_l': '1356-9597', 'issn': ['1356-9597', '1365-2443'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 45, 'referenced_works': ['https://openalex.org/W1503622815', 'https://openalex.org/W1516006437', 'https://openalex.org/W1554180547', 'https://openalex.org/W1973341497', 'https://openalex.org/W1974623218', 'https://openalex.org/W1976935056', 'https://openalex.org/W1992909271', 'https://openalex.org/W1993525477', 'https://openalex.org/W1998639983', 'https://openalex.org/W2007877183', 'https://openalex.org/W2011163535', 'https://openalex.org/W2017989706', 'https://openalex.org/W2023491365', 'https://openalex.org/W2034719507', 'https://openalex.org/W2039411295', 'https://openalex.org/W2057056702', 'https://openalex.org/W2057250255', 'https://openalex.org/W2065305645', 'https://openalex.org/W2065479320', 'https://openalex.org/W2074579328', 'https://openalex.org/W2078128181', 'https://openalex.org/W2080815080', 'https://openalex.org/W2082258814', 'https://openalex.org/W2086991973', 'https://openalex.org/W2094902224', 'https://openalex.org/W2096237314', 'https://openalex.org/W2098224915', 'https://openalex.org/W2101508231', 'https://openalex.org/W2108078777', 'https://openalex.org/W2111563936', 'https://openalex.org/W2132643489', 'https://openalex.org/W2137417707', 'https://openalex.org/W2147891181', 'https://openalex.org/W2162082053', 'https://openalex.org/W2171773153', 'https://openalex.org/W2195184589', 'https://openalex.org/W2325216703', 'https://openalex.org/W2331004399', 'https://openalex.org/W2440896660', 'https://openalex.org/W2467034934', 'https://openalex.org/W2549018048', 'https://openalex.org/W2570684882', 'https://openalex.org/W2606824156', 'https://openalex.org/W2713757953', 'https://openalex.org/W2953727082'], 'related_works': ['https://openalex.org/W4237091814', 'https://openalex.org/W4231313959', 'https://openalex.org/W2953727082', 'https://openalex.org/W2496469184', 'https://openalex.org/W2330598502', 'https://openalex.org/W2133577258', 'https://openalex.org/W2105558110', 'https://openalex.org/W2016258313', 'https://openalex.org/W1996322489', 'https://openalex.org/W1980117820'], 'abstract_inverted_index': {'Abstract': [0], 'The': [1], 'outcome': [2], 'of': [3, 24, 64, 89, 113], 'epigenetic': [4, 26, 47, 97], 'responses': [5, 48], 'to': [6, 41, 57, 102], 'stress': [7], 'depends': [8], 'strictly': [9], 'on': [10], 'genetic': [11], 'background,': [12], 'suggesting': [13], 'that': [14, 45, 59, 86, 104], 'altered': [15, 35], 'phenotypes,': [16], 'when': [17], 'induced,': [18], 'are': [19, 37], 'created': [20], 'by': [21], 'a': [22], 'combination': [23], 'induced': [25], 'factors': [27], 'and': [28, 39], 'pre‐existing': [29], 'allelic': [30, 66], 'ones.': [31], 'When': [32], 'individuals': [33, 94, 103], 'with': [34, 95], 'phenotypes': [36, 75], 'selected': [38, 93], 'subjected': [40], 'successive': [42], 'breeding,': [43], 'alleles': [44, 91], 'potentiate': [46], 'could': [49, 68, 99], 'accumulate': [50], 'in': [51, 72, 92, 110], 'offspring': [52], 'populations.': [53], 'It': [54], 'is': [55], 'reasonable': [56], 'suppose': [58], 'many,': [60], 'if': [61], 'not': [62], 'all,': [63], 'these': [65], 'genes': [67], 'also': [69], 'be': [70], 'involved': [71], 'creating': [73], 'new': [74], 'under': [76], 'nonstressful': [77], 'conditions.': [78], 'In': [79], 'this': [80], 'review,': [81], 'I': [82], 'discuss': [83], 'the': [84, 87, 106, 111], 'possibility': [85], 'accumulation': [88], 'such': [90], 'an': [96], 'phenotype': [98, 108], 'give': [100], 'rise': [101], 'exhibit': [105], 'same': [107], 'even': [109], 'absence': [112], 'stress.': [114]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2953727082', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}], 'updated_date': '2024-12-16T20:00:49.218254', 'created_date': '2019-07-12'}