Title: Ring-Closing Metathesis Strategies to Amino Acid-Derived P-Heterocycles
Abstract:Utilization of the ring-closing metathesis (RCM) reaction in the synthesis of a number of amino acid-derived 5- and 7-membered cyclic phosphorus-containing compounds is described. Coupling of achiral ...Utilization of the ring-closing metathesis (RCM) reaction in the synthesis of a number of amino acid-derived 5- and 7-membered cyclic phosphorus-containing compounds is described. Coupling of achiral and non-racemic allylic amines with P(V) and P(III) chlorides generates acyclic phosphorus-containing metathesis precursors. These templates undergo RCM in the presence of the Grubbs benzylidene catalyst to afford an array of amino acid-based P-heterocycles.Read More
Publication Year: 2001
Publication Date: 2001-01-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 9
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