Title: Synthesis of novel annulated uracils via domino Knoevenagel-hetero-Diels–Alder reaction in aqueous media
Abstract: An efficient synthesis of tetracyclic uracil derivatives (polycyclic pyrans) is achieved via domino Knoevenagel-hetero-Diels–Alder reactions of O-propargylated salicylaldehyde derivatives with 1,3-dimethylbarbituric acid in water as solvent in the presence of CuI. The products are formed in good yields.
Publication Year: 2008
Publication Date: 2008-09-19
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 41
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