Title: Heck Reactions Starting from Silyl Enol Ethers - A Simple One-Pot Nonaflation-Coupling Procedure for the Synthesis of 1,3-Dienes
Abstract:Starting from silyl enol ether 4 the corresponding alkenylnonaflate 5 was generated by treatment with nonafluorobutanesulfonyl fluoride (NfF) and a catalytic amount of tetra-n-butyl-ammonium fluoride ...Starting from silyl enol ether 4 the corresponding alkenylnonaflate 5 was generated by treatment with nonafluorobutanesulfonyl fluoride (NfF) and a catalytic amount of tetra-n-butyl-ammonium fluoride (TBAF). By Pd-catalysis 5 was directly Heck-coupled with a variety of olefins to furnish functionalized 1,3-dienes 6 - 12. This one-pot procedure could be extended to other silyl enol ethers and provides new synthetic options.Read More
Publication Year: 1997
Publication Date: 1997-10-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 23
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