Title: Reactions on a Solid Surface. A Simple, Economical, and Efficient Acylation of Alcohols and Amines over Al<sub>2</sub>O<sub>3</sub>
Abstract:Al(2)O(3) brings about a rapid acylation of a range of alcohols and amines with acid chlorides and acid anhydrides, respectively. Amines are easily Boc- and Cbz-protected on reaction with Boc-anhydrid...Al(2)O(3) brings about a rapid acylation of a range of alcohols and amines with acid chlorides and acid anhydrides, respectively. Amines are easily Boc- and Cbz-protected on reaction with Boc-anhydride and Cbz-Cl, respectively. The acylation of phenols is slow enough to allow chemoselective acylation of alcohols and amines in the presence of phenols.Read More
Publication Year: 2003
Publication Date: 2003-12-19
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 45
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