Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2949531974', 'doi': 'https://doi.org/10.7554/elife.45185', 'title': 'Conformational switches control early maturation of the eukaryotic small ribosomal subunit', 'display_name': 'Conformational switches control early maturation of the eukaryotic small ribosomal subunit', 'publication_year': 2019, 'publication_date': '2019-06-17', 'ids': {'openalex': 'https://openalex.org/W2949531974', 'doi': 'https://doi.org/10.7554/elife.45185', 'mag': '2949531974', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/31206356', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6579516'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.7554/elife.45185', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S1336409049', 'display_name': 'eLife', 'issn_l': '2050-084X', 'issn': ['2050-084X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311710', 'host_organization_name': 'eLife Sciences Publications Ltd', 'host_organization_lineage': ['https://openalex.org/P4310311710'], 'host_organization_lineage_names': ['eLife Sciences Publications Ltd'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://doi.org/10.7554/elife.45185', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5078909595', 'display_name': 'Mirjam Hunziker', 'orcid': 'https://orcid.org/0000-0002-2912-4993'}, 'institutions': [{'id': 'https://openalex.org/I83399316', 'display_name': 'Rockefeller University', 'ror': 'https://ror.org/0420db125', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I83399316']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Mirjam Hunziker', 'raw_affiliation_strings': ['Laboratory of Protein and Nucleic Acid Chemistry, The Rockefeller University, New York, United States'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Protein and Nucleic Acid Chemistry, The Rockefeller University, New York, United States', 'institution_ids': ['https://openalex.org/I83399316']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050628736', 'display_name': 'Jonas Barandun', 'orcid': 'https://orcid.org/0000-0003-2971-8190'}, 'institutions': [{'id': 'https://openalex.org/I83399316', 'display_name': 'Rockefeller University', 'ror': 'https://ror.org/0420db125', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I83399316']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jonas Barandun', 'raw_affiliation_strings': ['Laboratory of Protein and Nucleic Acid Chemistry, The Rockefeller University, New York, United States'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Protein and Nucleic Acid Chemistry, The Rockefeller University, New York, United States', 'institution_ids': ['https://openalex.org/I83399316']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087250666', 'display_name': 'Olga Buzovetsky', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I83399316', 'display_name': 'Rockefeller University', 'ror': 'https://ror.org/0420db125', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I83399316']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Olga Buzovetsky', 'raw_affiliation_strings': ['Laboratory of Protein and Nucleic Acid Chemistry, The Rockefeller University, New York, United States'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Protein and Nucleic Acid Chemistry, The Rockefeller University, New York, United States', 'institution_ids': ['https://openalex.org/I83399316']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034350731', 'display_name': 'Caitlin Steckler', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I83399316', 'display_name': 'Rockefeller University', 'ror': 'https://ror.org/0420db125', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I83399316']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Caitlin Steckler', 'raw_affiliation_strings': ['Proteomics Resource Center, The Rockefeller University, New York, United States'], 'affiliations': [{'raw_affiliation_string': 'Proteomics Resource Center, The Rockefeller University, New York, United States', 'institution_ids': ['https://openalex.org/I83399316']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026244741', 'display_name': 'Henrik Molina', 'orcid': 'https://orcid.org/0000-0001-8950-4990'}, 'institutions': [{'id': 'https://openalex.org/I83399316', 'display_name': 'Rockefeller University', 'ror': 'https://ror.org/0420db125', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I83399316']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Henrik Molina', 'raw_affiliation_strings': ['Proteomics Resource Center, The Rockefeller University, New York, United States'], 'affiliations': [{'raw_affiliation_string': 'Proteomics Resource Center, The Rockefeller University, New York, United States', 'institution_ids': ['https://openalex.org/I83399316']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5031074465', 'display_name': 'Sebastian Klinge', 'orcid': 'https://orcid.org/0000-0002-9373-4737'}, 'institutions': [{'id': 'https://openalex.org/I83399316', 'display_name': 'Rockefeller University', 'ror': 'https://ror.org/0420db125', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I83399316']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sebastian Klinge', 'raw_affiliation_strings': ['Laboratory of Protein and Nucleic Acid Chemistry, The Rockefeller University, New York, United States'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Protein and Nucleic Acid Chemistry, The Rockefeller University, New York, United States', 'institution_ids': ['https://openalex.org/I83399316']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3000, 'currency': 'USD', 'value_usd': 3000, 'provenance': 'doaj'}, 'apc_paid': {'value': 3000, 'currency': 'USD', 'value_usd': 3000, 'provenance': 'doaj'}, 'fwci': 2.472, 'has_fulltext': False, 'cited_by_count': 37, 'citation_normalized_percentile': {'value': 0.999983, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '8', 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11482', 'display_name': 'RNA Methylation and Modification in Gene Expression', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11482', 'display_name': 'RNA Methylation and Modification in Gene Expression', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10521', 'display_name': 'Ribosome Structure and Translation Mechanisms', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10604', 'display_name': 'Regulation of RNA Processing and Function', 'score': 0.9946, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/eukaryotic-ribosome', 'display_name': 'Eukaryotic Ribosome', 'score': 0.6442094}, {'id': 'https://openalex.org/keywords/ribosome-biogenesis', 'display_name': 'ribosome biogenesis', 'score': 0.602534}, {'id': 'https://openalex.org/keywords/5.8s-ribosomal-rna', 'display_name': '5.8S ribosomal RNA', 'score': 0.57484794}, {'id': 'https://openalex.org/keywords/rna-phase-transitions', 'display_name': 'RNA Phase Transitions', 'score': 0.542181}, {'id': 'https://openalex.org/keywords/rna-structure', 'display_name': 'RNA Structure', 'score': 0.518444}, {'id': 'https://openalex.org/keywords/trna-fragments', 'display_name': 'tRNA fragments', 'score': 0.506035}, {'id': 'https://openalex.org/keywords/rna-polymerase-i', 'display_name': 'RNA polymerase I', 'score': 0.46278813}, {'id': 'https://openalex.org/keywords/ribosomal-protein', 'display_name': 'Ribosomal protein', 'score': 0.4331828}, {'id': 'https://openalex.org/keywords/transcription', 'display_name': 'Transcription (linguistics)', 'score': 0.4132836}], 'concepts': [{'id': 'https://openalex.org/C2779419633', 'wikidata': 'https://www.wikidata.org/wiki/Q7322423', 'display_name': 'Ribosome biogenesis', 'level': 5, 'score': 0.85738003}, {'id': 'https://openalex.org/C67905577', 'wikidata': 'https://www.wikidata.org/wiki/Q215980', 'display_name': 'Ribosomal RNA', 'level': 3, 'score': 0.6918756}, {'id': 'https://openalex.org/C129194359', 'wikidata': 'https://www.wikidata.org/wiki/Q2636953', 'display_name': 'Eukaryotic Ribosome', 'level': 5, 'score': 0.6442094}, {'id': 'https://openalex.org/C88478588', 'wikidata': 'https://www.wikidata.org/wiki/Q42244', 'display_name': 'Ribosome', 'level': 4, 'score': 0.5791775}, {'id': 'https://openalex.org/C98098607', 'wikidata': 'https://www.wikidata.org/wiki/Q4639691', 'display_name': '5.8S ribosomal RNA', 'level': 5, 'score': 0.57484794}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5554168}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.53080606}, {'id': 'https://openalex.org/C112755997', 'wikidata': 'https://www.wikidata.org/wiki/Q3827874', 'display_name': 'Eukaryotic Large Ribosomal Subunit', 'level': 5, 'score': 0.48675585}, {'id': 'https://openalex.org/C75934600', 'wikidata': 'https://www.wikidata.org/wiki/Q419245', 'display_name': 'Ribonucleoprotein', 'level': 4, 'score': 0.46492222}, {'id': 'https://openalex.org/C25281209', 'wikidata': 'https://www.wikidata.org/wiki/Q3502188', 'display_name': 'RNA polymerase I', 'level': 5, 'score': 0.46278813}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.43937427}, {'id': 'https://openalex.org/C38062823', 'wikidata': 'https://www.wikidata.org/wiki/Q3408228', 'display_name': 'Ribosomal protein', 'level': 5, 'score': 0.4331828}, {'id': 'https://openalex.org/C301363', 'wikidata': 'https://www.wikidata.org/wiki/Q4637383', 'display_name': 'Eukaryotic Small Ribosomal Subunit', 'level': 5, 'score': 0.42221823}, {'id': 'https://openalex.org/C155794727', 'wikidata': 'https://www.wikidata.org/wiki/Q2306414', 'display_name': 'Internal transcribed spacer', 'level': 4, 'score': 0.41718107}, {'id': 'https://openalex.org/C179926584', 'wikidata': 'https://www.wikidata.org/wiki/Q207714', 'display_name': 'Transcription (linguistics)', 'level': 2, 'score': 0.4132836}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.33720183}, {'id': 'https://openalex.org/C41258723', 'wikidata': 'https://www.wikidata.org/wiki/Q2919111', 'display_name': 'RNA-dependent RNA polymerase', 'level': 4, 'score': 0.10935813}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.08271015}, {'id': 'https://openalex.org/C41895202', 'wikidata': 'https://www.wikidata.org/wiki/Q8162', 'display_name': 'Linguistics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C138885662', 'wikidata': 'https://www.wikidata.org/wiki/Q5891', 'display_name': 'Philosophy', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D012322', 'descriptor_name': 'RNA Precursors', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D012269', 'descriptor_name': 'Ribosomal Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D054682', 'descriptor_name': 'Ribosome Subunits, Small, Eukaryotic', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D029701', 'descriptor_name': 'Saccharomyces cerevisiae Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D020285', 'descriptor_name': 'Cryoelectron Microscopy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005057', 'descriptor_name': 'Eukaryotic Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005057', 'descriptor_name': 'Eukaryotic Cells', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008958', 'descriptor_name': 'Models, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008968', 'descriptor_name': 'Molecular Conformation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000072417', 'descriptor_name': 'Protein Domains', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012322', 'descriptor_name': 'RNA Precursors', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012322', 'descriptor_name': 'RNA Precursors', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D012322', 'descriptor_name': 'RNA Precursors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012337', 'descriptor_name': 'RNA, Ribosomal, 18S', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012337', 'descriptor_name': 'RNA, Ribosomal, 18S', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D012337', 'descriptor_name': 'RNA, Ribosomal, 18S', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012337', 'descriptor_name': 'RNA, Ribosomal, 18S', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D012269', 'descriptor_name': 'Ribosomal Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012269', 'descriptor_name': 'Ribosomal Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D012269', 'descriptor_name': 'Ribosomal Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D054679', 'descriptor_name': 'Ribosome Subunits, Small', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054679', 'descriptor_name': 'Ribosome Subunits, Small', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D054679', 'descriptor_name': 'Ribosome Subunits, Small', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D054679', 'descriptor_name': 'Ribosome Subunits, Small', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D054682', 'descriptor_name': 'Ribosome Subunits, Small, Eukaryotic', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D054682', 'descriptor_name': 'Ribosome Subunits, Small, Eukaryotic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054682', 'descriptor_name': 'Ribosome Subunits, Small, Eukaryotic', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D029701', 'descriptor_name': 'Saccharomyces cerevisiae Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D029701', 'descriptor_name': 'Saccharomyces cerevisiae Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D029701', 'descriptor_name': 'Saccharomyces cerevisiae Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.7554/elife.45185', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S1336409049', 'display_name': 'eLife', 'issn_l': '2050-084X', 'issn': ['2050-084X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311710', 'host_organization_name': 'eLife Sciences Publications Ltd', 'host_organization_lineage': ['https://openalex.org/P4310311710'], 'host_organization_lineage_names': ['eLife Sciences Publications Ltd'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/cf5ad240ed714a808a96f003f8aa5dc8', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc6579516', 'pdf_url': 'https://europepmc.org/articles/pmc6579516?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579516', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/31206356', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.7554/elife.45185', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S1336409049', 'display_name': 'eLife', 'issn_l': '2050-084X', 'issn': ['2050-084X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311710', 'host_organization_name': 'eLife Sciences Publications Ltd', 'host_organization_lineage': ['https://openalex.org/P4310311710'], 'host_organization_lineage_names': ['eLife Sciences Publications Ltd'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320306151', 'funder_display_name': 'Alfred P. Sloan Foundation', 'award_id': None}, {'funder': 'https://openalex.org/F4320309418', 'funder_display_name': 'Irma T. Hirschl Trust', 'award_id': None}, {'funder': 'https://openalex.org/F4320314691', 'funder_display_name': 'Robertson Foundation', 'award_id': None}, {'funder': 'https://openalex.org/F4320320924', 'funder_display_name': 'Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung', 'award_id': '155515'}, {'funder': 'https://openalex.org/F4320332161', 'funder_display_name': 'National Institutes of Health', 'award_id': '1DP2GM123459'}], 'datasets': [], 'versions': [], 'referenced_works_count': 43, 'referenced_works': ['https://openalex.org/W1966765568', 'https://openalex.org/W1974631225', 'https://openalex.org/W1983499457', 'https://openalex.org/W1986656413', 'https://openalex.org/W1991350843', 'https://openalex.org/W2013303176', 'https://openalex.org/W2016680661', 'https://openalex.org/W2020237198', 'https://openalex.org/W2035503835', 'https://openalex.org/W2047682618', 'https://openalex.org/W2113580266', 'https://openalex.org/W2114622716', 'https://openalex.org/W2121450976', 'https://openalex.org/W2128551987', 'https://openalex.org/W2132629607', 'https://openalex.org/W2133152095', 'https://openalex.org/W2140003283', 'https://openalex.org/W2140224280', 'https://openalex.org/W2142161929', 'https://openalex.org/W2142906105', 'https://openalex.org/W2170776626', 'https://openalex.org/W2180229411', 'https://openalex.org/W2301441647', 'https://openalex.org/W2432427150', 'https://openalex.org/W2463195069', 'https://openalex.org/W2471036526', 'https://openalex.org/W2531577274', 'https://openalex.org/W2562544371', 'https://openalex.org/W2571083978', 'https://openalex.org/W2578197026', 'https://openalex.org/W2587625522', 'https://openalex.org/W2594366997', 'https://openalex.org/W2734356283', 'https://openalex.org/W2743052511', 'https://openalex.org/W2757370337', 'https://openalex.org/W2764176217', 'https://openalex.org/W2786780189', 'https://openalex.org/W2788238068', 'https://openalex.org/W2790889101', 'https://openalex.org/W2899714098', 'https://openalex.org/W2901941802', 'https://openalex.org/W2953320394', 'https://openalex.org/W4246412588'], 'related_works': ['https://openalex.org/W4353112023', 'https://openalex.org/W4286490885', 'https://openalex.org/W4224244449', 'https://openalex.org/W2517092495', 'https://openalex.org/W2305275542', 'https://openalex.org/W2157475454', 'https://openalex.org/W2146757543', 'https://openalex.org/W2138620065', 'https://openalex.org/W2093750110', 'https://openalex.org/W1996959647'], 'abstract_inverted_index': {'Eukaryotic': [0], 'ribosome': [1, 37, 149], 'biogenesis': [2, 69], 'is': [3, 26], 'initiated': [4], 'with': [5, 40], 'the': [6, 12, 19, 29, 45, 48, 60, 79, 84, 87, 104, 110, 132, 140], 'transcription': [7], 'of': [8, 22, 36, 47, 59, 78, 86, 103, 134, 142, 148], 'pre-ribosomal': [9, 41, 107], 'RNA': [10, 42, 92, 96], 'at': [11], '5’': [13, 88, 111], 'external': [14, 89, 112], 'transcribed': [15, 90, 113], 'spacer,': [16], 'which': [17], 'directs': [18], 'early': [20, 146], 'association': [21, 35], 'assembly': [23, 38, 75, 108], 'factors': [24, 39, 70], 'but': [25], 'absent': [27], 'from': [28], 'mature': [30], 'ribosome.': [31], 'The': [32, 73], 'subsequent': [33], 'co-transcriptional': [34], 'results': [43], 'in': [44, 71, 124], 'formation': [46], 'small': [49, 61, 80], 'subunit': [50, 63, 81], 'processome.': [51], 'Here': [52], 'we': [53], 'show': [54], 'that': [55], 'stable': [56], 'rRNA': [57], 'domains': [58], 'ribosomal': [62, 95], 'can': [64, 127], 'independently': [65], 'recruit': [66], 'their': [67], 'own': [68], 'vivo.': [72], 'final': [74], 'and': [76, 93, 137], 'compaction': [77], 'processome': [82], 'requires': [83], 'presence': [85], 'spacer': [91, 114], 'all': [94], 'domains.': [97], 'Additionally,': [98], 'our': [99], 'cryo-electron': [100], 'microscopy': [101], 'structure': [102], 'earliest': [105], 'nucleolar': [106], '-': [109], 'ribonucleoprotein': [115], '–': [116], 'provides': [117], 'a': [118], 'mechanism': [119], 'for': [120], 'how': [121], 'conformational': [122], 'changes': [123], 'multi-protein': [125], 'complexes': [126], 'be': [128], 'employed': [129], 'to': [130], 'regulate': [131], 'accessibility': [133], 'binding': [135], 'sites': [136], 'therefore': [138], 'define': [139], 'chronology': [141], 'maturation': [143], 'events': [144], 'during': [145], 'stages': [147], 'assembly.': [150]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2949531974', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 10}, {'year': 2021, 'cited_by_count': 8}, {'year': 2020, 'cited_by_count': 11}, {'year': 2019, 'cited_by_count': 1}], 'updated_date': '2024-09-14T14:00:21.510486', 'created_date': '2019-06-27'}