Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2947531650', 'doi': 'https://doi.org/10.1128/msphere.00142-19', 'title': 'Stage-Specific and Selective Delivery of Caged Azidosugars into the Intracellular Parasite <i>Toxoplasma gondii</i> by Using an Esterase-Ester Pair Technique', 'display_name': 'Stage-Specific and Selective Delivery of Caged Azidosugars into the Intracellular Parasite <i>Toxoplasma gondii</i> by Using an Esterase-Ester Pair Technique', 'publication_year': 2019, 'publication_date': '2019-05-28', 'ids': {'openalex': 'https://openalex.org/W2947531650', 'doi': 'https://doi.org/10.1128/msphere.00142-19', 'mag': '2947531650', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/31142619', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6541734'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/msphere.00142-19', 'pdf_url': 'https://msphere.asm.org/content/msph/4/3/e00142-19.full.pdf', 'source': {'id': 'https://openalex.org/S4210207018', 'display_name': 'mSphere', 'issn_l': '2379-5042', 'issn': ['2379-5042'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://msphere.asm.org/content/msph/4/3/e00142-19.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5072059139', 'display_name': 'Tadakimi Tomita', 'orcid': 'https://orcid.org/0000-0001-8809-3333'}, 'institutions': [{'id': 'https://openalex.org/I129975664', 'display_name': 'Albert Einstein College of Medicine', 'ror': 'https://ror.org/05cf8a891', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I129975664', 'https://openalex.org/I4210112371']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Tadakimi Tomita', 'raw_affiliation_strings': ['Department of Pathology, Albert Einstein College of Medicine, New York, New York, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Albert Einstein College of Medicine, New York, New York, USA', 'institution_ids': ['https://openalex.org/I129975664']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100403938', 'display_name': 'Hua Wang', 'orcid': 'https://orcid.org/0000-0002-2605-5697'}, 'institutions': [{'id': 'https://openalex.org/I123431417', 'display_name': 'Scripps Research Institute', 'ror': 'https://ror.org/02dxx6824', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I123431417']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Hua Wang', 'raw_affiliation_strings': ['Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, USA', 'institution_ids': ['https://openalex.org/I123431417']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090263634', 'display_name': 'Peng Wu', 'orcid': 'https://orcid.org/0000-0002-5204-0229'}, 'institutions': [{'id': 'https://openalex.org/I123431417', 'display_name': 'Scripps Research Institute', 'ror': 'https://ror.org/02dxx6824', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I123431417']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Peng Wu', 'raw_affiliation_strings': ['Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, USA', 'institution_ids': ['https://openalex.org/I123431417']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5066856917', 'display_name': 'Louis M. Weiss', 'orcid': 'https://orcid.org/0000-0002-0357-7396'}, 'institutions': [{'id': 'https://openalex.org/I129975664', 'display_name': 'Albert Einstein College of Medicine', 'ror': 'https://ror.org/05cf8a891', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I129975664', 'https://openalex.org/I4210112371']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Louis M. Weiss', 'raw_affiliation_strings': ['Department of Medicine, Albert Einstein College of Medicine, New York, New York, USA', 'Department of Pathology, Albert Einstein College of Medicine, New York, New York, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Albert Einstein College of Medicine, New York, New York, USA', 'institution_ids': ['https://openalex.org/I129975664']}, {'raw_affiliation_string': 'Department of Medicine, Albert Einstein College of Medicine, New York, New York, USA', 'institution_ids': ['https://openalex.org/I129975664']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3500, 'currency': 'USD', 'value_usd': 3500, 'provenance': 'doaj'}, 'apc_paid': {'value': 3500, 'currency': 'USD', 'value_usd': 3500, 'provenance': 'doaj'}, 'fwci': 0.313, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 2, 'citation_normalized_percentile': {'value': 0.446875, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 69, 'max': 74}, 'biblio': {'volume': '4', 'issue': '3', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11155', 'display_name': 'Toxoplasma gondii Research Studies', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2405', 'display_name': 'Parasitology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11155', 'display_name': 'Toxoplasma gondii Research Studies', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2405', 'display_name': 'Parasitology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10625', 'display_name': 'Herpesvirus Infections and Treatments', 'score': 0.9883, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10981', 'display_name': 'Cytomegalovirus and herpesvirus research', 'score': 0.9797, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/intracellular-parasite', 'display_name': 'Intracellular parasite', 'score': 0.7443394}, {'id': 'https://openalex.org/keywords/esterase', 'display_name': 'Esterase', 'score': 0.51175857}, {'id': 'https://openalex.org/keywords/protozoan-parasite', 'display_name': 'Protozoan parasite', 'score': 0.47119403}], 'concepts': [{'id': 'https://openalex.org/C2778128430', 'wikidata': 'https://www.wikidata.org/wiki/Q131003', 'display_name': 'Toxoplasma gondii', 'level': 3, 'score': 0.9478772}, {'id': 'https://openalex.org/C79879829', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Intracellular', 'level': 2, 'score': 0.911371}, {'id': 'https://openalex.org/C153726182', 'wikidata': 'https://www.wikidata.org/wiki/Q3720909', 'display_name': 'Intracellular parasite', 'level': 3, 'score': 0.7443394}, {'id': 'https://openalex.org/C71928629', 'wikidata': 'https://www.wikidata.org/wiki/Q804206', 'display_name': 'Parasite hosting', 'level': 2, 'score': 0.66628796}, {'id': 'https://openalex.org/C2777261171', 'wikidata': 'https://www.wikidata.org/wiki/Q418750', 'display_name': 'Esterase', 'level': 3, 'score': 0.51175857}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.504115}, {'id': 'https://openalex.org/C3019792204', 'wikidata': 'https://www.wikidata.org/wiki/Q353172', 'display_name': 'Protozoan parasite', 'level': 3, 'score': 0.47119403}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.46279216}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.38231936}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.32145378}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.24951297}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.14507395}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.0910334}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.049636006}, {'id': 'https://openalex.org/C136764020', 'wikidata': 'https://www.wikidata.org/wiki/Q466', 'display_name': 'World Wide Web', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001386', 'descriptor_name': 'Azides', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D057930', 'descriptor_name': 'Click Chemistry', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D004950', 'descriptor_name': 'Esterases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D004952', 'descriptor_name': 'Esters', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D006023', 'descriptor_name': 'Glycoproteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D014122', 'descriptor_name': 'Toxoplasma', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001692', 'descriptor_name': 'Biological Transport', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D000075082', 'descriptor_name': 'Proof of Concept Study', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015800', 'descriptor_name': 'Protozoan Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013552', 'descriptor_name': 'Swine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/msphere.00142-19', 'pdf_url': 'https://msphere.asm.org/content/msph/4/3/e00142-19.full.pdf', 'source': {'id': 'https://openalex.org/S4210207018', 'display_name': 'mSphere', 'issn_l': '2379-5042', 'issn': ['2379-5042'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc6541734', 'pdf_url': 'https://europepmc.org/articles/pmc6541734?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541734', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/31142619', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/msphere.00142-19', 'pdf_url': 'https://msphere.asm.org/content/msph/4/3/e00142-19.full.pdf', 'source': {'id': 'https://openalex.org/S4210207018', 'display_name': 'mSphere', 'issn_l': '2379-5042', 'issn': ['2379-5042'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320337354', 'funder_display_name': 'National Institute of General Medical Sciences', 'award_id': 'K12 GM102779'}, {'funder': 'https://openalex.org/F4320337355', 'funder_display_name': 'National Institute of Allergy and Infectious Diseases', 'award_id': 'R21 AI123495'}], 'datasets': [], 'versions': [], 'referenced_works_count': 24, 'referenced_works': ['https://openalex.org/W1892352924', 'https://openalex.org/W1988658450', 'https://openalex.org/W1996336718', 'https://openalex.org/W1998326662', 'https://openalex.org/W2002340960', 'https://openalex.org/W2031114810', 'https://openalex.org/W2054269398', 'https://openalex.org/W2057570438', 'https://openalex.org/W2065654101', 'https://openalex.org/W2080670791', 'https://openalex.org/W2112759148', 'https://openalex.org/W2121624499', 'https://openalex.org/W2131025240', 'https://openalex.org/W2131043951', 'https://openalex.org/W2161093157', 'https://openalex.org/W2199395563', 'https://openalex.org/W2295952587', 'https://openalex.org/W2338693143', 'https://openalex.org/W2573080176', 'https://openalex.org/W2580625752', 'https://openalex.org/W2788593837', 'https://openalex.org/W2804205785', 'https://openalex.org/W2887186938', 'https://openalex.org/W2900461565'], 'related_works': ['https://openalex.org/W4298313298', 'https://openalex.org/W3004449527', 'https://openalex.org/W2947531650', 'https://openalex.org/W2916040195', 'https://openalex.org/W2893492741', 'https://openalex.org/W2811406123', 'https://openalex.org/W2074189358', 'https://openalex.org/W2017025302', 'https://openalex.org/W2012423405', 'https://openalex.org/W1983557113'], 'abstract_inverted_index': {'is': [0, 43], 'an': [1], 'obligate': [2], 'intracellular': [3], 'parasite': [4], 'that': [5], 'chronically': [6], 'infects': [7], 'up': [8], 'to': [9, 45], 'a': [10, 32], 'third': [11], 'of': [12, 22, 37], 'the': [13, 20, 25, 35], 'human': [14], 'population.': [15], 'The': [16, 40], 'parasites': [17], 'persist': [18], 'in': [19, 24], 'form': [21], 'cysts': [23], 'central': [26], 'nervous': [27], 'system': [28], 'and': [29], 'serve': [30], 'as': [31], 'reservoir': [33], 'for': [34], 'reactivation': [36], 'toxoplasmic': [38], 'encephalitis.': [39], 'cyst': [41], 'wall': [42], 'known': [44], 'have': [46], 'abundant': [47]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2947531650', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}], 'updated_date': '2024-12-17T20:44:17.918815', 'created_date': '2019-06-07'}