Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2945715301', 'doi': 'https://doi.org/10.1016/j.celrep.2019.04.091', 'title': 'Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies', 'display_name': 'Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies', 'publication_year': 2019, 'publication_date': '2019-05-01', 'ids': {'openalex': 'https://openalex.org/W2945715301', 'doi': 'https://doi.org/10.1016/j.celrep.2019.04.091', 'mag': '2945715301', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/31116985'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.celrep.2019.04.091', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S169236886', 'display_name': 'Cell Reports', 'issn_l': '2211-1247', 'issn': ['2211-1247', '2639-1856'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://doi.org/10.1016/j.celrep.2019.04.091', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5000205943', 'display_name': 'Ivan Perrot', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210143497', 'display_name': 'Innate Pharma (France)', 'ror': 'https://ror.org/055wa9133', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210143497']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Ivan Perrot', 'raw_affiliation_strings': ['Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France'], 'affiliations': [{'raw_affiliation_string': 'Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France', 'institution_ids': ['https://openalex.org/I4210143497']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012204939', 'display_name': 'Henri-Alexandre Michaud', 'orcid': 'https://orcid.org/0000-0002-6165-1929'}, 'institutions': [{'id': 'https://openalex.org/I4210140335', 'display_name': 'Institut de Recherche en Cancérologie de Montpellier', 'ror': 'https://ror.org/03capj968', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I19894307', 'https://openalex.org/I4210137371', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210140335']}, {'id': 'https://openalex.org/I19894307', 'display_name': 'Université de Montpellier', 'ror': 'https://ror.org/051escj72', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I19894307']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Henri-Alexandre Michaud', 'raw_affiliation_strings': ['IRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, 34298 Montpellier, France'], 'affiliations': [{'raw_affiliation_string': 'IRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, 34298 Montpellier, France', 'institution_ids': ['https://openalex.org/I4210140335', 'https://openalex.org/I19894307', 'https://openalex.org/I154526488']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086701944', 'display_name': 'Marc Giraudon-Paoli', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210143497', 'display_name': 'Innate Pharma (France)', 'ror': 'https://ror.org/055wa9133', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210143497']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Marc Giraudon-Paoli', 'raw_affiliation_strings': ['Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France'], 'affiliations': [{'raw_affiliation_string': 'Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France', 'institution_ids': ['https://openalex.org/I4210143497']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017595870', 'display_name': 'Séverine Augier', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210143497', 'display_name': 'Innate Pharma (France)', 'ror': 'https://ror.org/055wa9133', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210143497']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Séverine Augier', 'raw_affiliation_strings': ['Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France'], 'affiliations': [{'raw_affiliation_string': 'Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France', 'institution_ids': ['https://openalex.org/I4210143497']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018332148', 'display_name': 'Aurélie Docquier', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210091113', 'display_name': 'OREGA Biotech (France)', 'ror': 'https://ror.org/00dwde739', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210091113']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Aurélie Docquier', 'raw_affiliation_strings': ['OREGA Biotech, 69130 Ecully, France'], 'affiliations': [{'raw_affiliation_string': 'OREGA Biotech, 69130 Ecully, France', 'institution_ids': ['https://openalex.org/I4210091113']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048156654', 'display_name': 'Laurent Gros', 'orcid': 'https://orcid.org/0000-0001-5116-2980'}, 'institutions': [{'id': 'https://openalex.org/I4210140335', 'display_name': 'Institut de Recherche en Cancérologie de Montpellier', 'ror': 'https://ror.org/03capj968', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I19894307', 'https://openalex.org/I4210137371', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210140335']}, {'id': 'https://openalex.org/I19894307', 'display_name': 'Université de Montpellier', 'ror': 'https://ror.org/051escj72', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I19894307']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Laurent Gros', 'raw_affiliation_strings': ['IRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, 34298 Montpellier, France'], 'affiliations': [{'raw_affiliation_string': 'IRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, 34298 Montpellier, France', 'institution_ids': ['https://openalex.org/I4210140335', 'https://openalex.org/I19894307', 'https://openalex.org/I154526488']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005742674', 'display_name': 'Rachel Courtois', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210143497', 'display_name': 'Innate Pharma (France)', 'ror': 'https://ror.org/055wa9133', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210143497']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Rachel Courtois', 'raw_affiliation_strings': ['Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France'], 'affiliations': [{'raw_affiliation_string': 'Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France', 'institution_ids': ['https://openalex.org/I4210143497']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5058764481', 'display_name': 'Cécile Dejou', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210091113', 'display_name': 'OREGA Biotech (France)', 'ror': 'https://ror.org/00dwde739', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210091113']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Cécile Déjou', 'raw_affiliation_strings': ['OREGA Biotech, 69130 Ecully, France'], 'affiliations': [{'raw_affiliation_string': 'OREGA Biotech, 69130 Ecully, France', 'institution_ids': ['https://openalex.org/I4210091113']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068862096', 'display_name': 'Diana Jecko', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210143497', 'display_name': 'Innate Pharma (France)', 'ror': 'https://ror.org/055wa9133', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210143497']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Diana Jecko', 'raw_affiliation_strings': ['Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France'], 'affiliations': [{'raw_affiliation_string': 'Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France', 'institution_ids': ['https://openalex.org/I4210143497']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060888102', 'display_name': 'O. Becquart', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210140335', 'display_name': 'Institut de Recherche en Cancérologie de Montpellier', 'ror': 'https://ror.org/03capj968', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I19894307', 'https://openalex.org/I4210137371', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210140335']}, {'id': 'https://openalex.org/I19894307', 'display_name': 'Université de Montpellier', 'ror': 'https://ror.org/051escj72', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I19894307']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I4210093292', 'display_name': 'Centre Hospitalier Universitaire de Montpellier', 'ror': 'https://ror.org/00mthsf17', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210093292']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Ondine Becquart', 'raw_affiliation_strings': ['Département de Dermatologie, Centre Hospitalier Régional Universitaire de Montpellier et Faculté de Médecine, Université de Montpellier, 34295 Montpellier, France', 'IRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, 34298 Montpellier, France'], 'affiliations': [{'raw_affiliation_string': 'IRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, 34298 Montpellier, France', 'institution_ids': ['https://openalex.org/I4210140335', 'https://openalex.org/I19894307', 'https://openalex.org/I154526488']}, {'raw_affiliation_string': 'Département de Dermatologie, Centre Hospitalier Régional Universitaire de Montpellier et Faculté de Médecine, Université de Montpellier, 34295 Montpellier, France', 'institution_ids': ['https://openalex.org/I4210093292', 'https://openalex.org/I19894307']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000113058', 'display_name': 'Hélène Rispaud-Blanc', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210143497', 'display_name': 'Innate Pharma (France)', 'ror': 'https://ror.org/055wa9133', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210143497']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Hélène Rispaud-Blanc', 'raw_affiliation_strings': ['Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France'], 'affiliations': [{'raw_affiliation_string': 'Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France', 'institution_ids': ['https://openalex.org/I4210143497']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061502185', 'display_name': 'Laurent Gauthier', 'orcid': 'https://orcid.org/0000-0003-3225-4825'}, 'institutions': [{'id': 'https://openalex.org/I4210143497', 'display_name': 'Innate Pharma (France)', 'ror': 'https://ror.org/055wa9133', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210143497']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Laurent Gauthier', 'raw_affiliation_strings': ['Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France'], 'affiliations': [{'raw_affiliation_string': 'Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France', 'institution_ids': ['https://openalex.org/I4210143497']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069095465', 'display_name': 'Benjamín Rossi', 'orcid': 'https://orcid.org/0000-0001-5523-0602'}, 'institutions': [{'id': 'https://openalex.org/I4210143497', 'display_name': 'Innate Pharma (France)', 'ror': 'https://ror.org/055wa9133', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210143497']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Benjamin Rossi', 'raw_affiliation_strings': ['Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France'], 'affiliations': [{'raw_affiliation_string': 'Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France', 'institution_ids': ['https://openalex.org/I4210143497']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086076230', 'display_name': 'Stéphanie Chanteux', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210143497', 'display_name': 'Innate Pharma (France)', 'ror': 'https://ror.org/055wa9133', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210143497']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Stéphanie Chanteux', 'raw_affiliation_strings': ['Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France'], 'affiliations': [{'raw_affiliation_string': 'Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France', 'institution_ids': ['https://openalex.org/I4210143497']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5058333723', 'display_name': 'Nicolas Gourdin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210143497', 'display_name': 'Innate Pharma (France)', 'ror': 'https://ror.org/055wa9133', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210143497']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Nicolas Gourdin', 'raw_affiliation_strings': ['Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France'], 'affiliations': [{'raw_affiliation_string': 'Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France', 'institution_ids': ['https://openalex.org/I4210143497']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070218673', 'display_name': 'Béatrice Amigues', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210146787', 'display_name': 'Architecture et Fonction des Macromolécules Biologiques', 'ror': 'https://ror.org/04jm8zw14', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I21491767', 'https://openalex.org/I4210088668', 'https://openalex.org/I4210096427', 'https://openalex.org/I4210146787']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I21491767', 'display_name': 'Aix-Marseille Université', 'ror': 'https://ror.org/035xkbk20', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I21491767']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Beatrice Amigues', 'raw_affiliation_strings': ['CNRS, Aix Marseille Université, AFMB, Architecture et Fonction des Macromolécules Biologiques, 13009 Marseille, France'], 'affiliations': [{'raw_affiliation_string': 'CNRS, Aix Marseille Université, AFMB, Architecture et Fonction des Macromolécules Biologiques, 13009 Marseille, France', 'institution_ids': ['https://openalex.org/I4210146787', 'https://openalex.org/I1294671590', 'https://openalex.org/I21491767']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085766942', 'display_name': 'Alain Roussel', 'orcid': 'https://orcid.org/0000-0002-9831-3261'}, 'institutions': [{'id': 'https://openalex.org/I4210146787', 'display_name': 'Architecture et Fonction des Macromolécules Biologiques', 'ror': 'https://ror.org/04jm8zw14', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I21491767', 'https://openalex.org/I4210088668', 'https://openalex.org/I4210096427', 'https://openalex.org/I4210146787']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I21491767', 'display_name': 'Aix-Marseille Université', 'ror': 'https://ror.org/035xkbk20', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I21491767']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Alain Roussel', 'raw_affiliation_strings': ['CNRS, Aix Marseille Université, AFMB, Architecture et Fonction des Macromolécules Biologiques, 13009 Marseille, France'], 'affiliations': [{'raw_affiliation_string': 'CNRS, Aix Marseille Université, AFMB, Architecture et Fonction des Macromolécules Biologiques, 13009 Marseille, France', 'institution_ids': ['https://openalex.org/I4210146787', 'https://openalex.org/I1294671590', 'https://openalex.org/I21491767']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040446667', 'display_name': 'Armand Bensussan', 'orcid': 'https://orcid.org/0000-0002-0409-2497'}, 'institutions': [{'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I204730241', 'display_name': 'Université Paris Cité', 'ror': 'https://ror.org/05f82e368', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I204730241']}, {'id': 'https://openalex.org/I169173203', 'display_name': 'Délégation Paris 7', 'ror': 'https://ror.org/00bw5n526', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I169173203']}, {'id': 'https://openalex.org/I4210091437', 'display_name': 'Sorbonne Paris Cité', 'ror': 'https://ror.org/001z21q04', 'country_code': 'FR', 'type': 'other', 'lineage': ['https://openalex.org/I4210091437']}, {'id': 'https://openalex.org/I4387154437', 'display_name': 'HIPI - Immunologie humaine, physiopathologie et immunithérapie', 'ror': 'https://ror.org/008e1sp22', 'country_code': None, 'type': 'facility', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I204730241', 'https://openalex.org/I4387154437']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Armand Bensussan', 'raw_affiliation_strings': ['Institut National de la Santé et de la Recherche Médicale (INSERM) UMR-S 976, Université Paris Diderot, Sorbonne Paris Cité, Laboratory of Human Immunology, Pathophysiology and Immunotherapy, 75475 Paris, France'], 'affiliations': [{'raw_affiliation_string': 'Institut National de la Santé et de la Recherche Médicale (INSERM) UMR-S 976, Université Paris Diderot, Sorbonne Paris Cité, Laboratory of Human Immunology, Pathophysiology and Immunotherapy, 75475 Paris, France', 'institution_ids': ['https://openalex.org/I154526488', 'https://openalex.org/I204730241', 'https://openalex.org/I169173203', 'https://openalex.org/I4210091437', 'https://openalex.org/I4387154437']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5107640669', 'display_name': 'Jean‐François Eliaou', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210093292', 'display_name': 'Centre Hospitalier Universitaire de Montpellier', 'ror': 'https://ror.org/00mthsf17', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210093292']}, {'id': 'https://openalex.org/I19894307', 'display_name': 'Université de Montpellier', 'ror': 'https://ror.org/051escj72', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I19894307']}, {'id': 'https://openalex.org/I4210140335', 'display_name': 'Institut de Recherche en Cancérologie de Montpellier', 'ror': 'https://ror.org/03capj968', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I19894307', 'https://openalex.org/I4210137371', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210140335']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Jean-François Eliaou', 'raw_affiliation_strings': ["Département d'Immunologie, Centre Hospitalier Régional Universitaire de Montpellier et Faculté de Médecine, Université de Montpellier, 34295 Montpellier, France", 'IRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, 34298 Montpellier, France'], 'affiliations': [{'raw_affiliation_string': "Département d'Immunologie, Centre Hospitalier Régional Universitaire de Montpellier et Faculté de Médecine, Université de Montpellier, 34295 Montpellier, France", 'institution_ids': ['https://openalex.org/I4210093292', 'https://openalex.org/I19894307']}, {'raw_affiliation_string': 'IRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, 34298 Montpellier, France', 'institution_ids': ['https://openalex.org/I4210140335', 'https://openalex.org/I19894307', 'https://openalex.org/I154526488']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111775512', 'display_name': 'Jérémy Bastid', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210091113', 'display_name': 'OREGA Biotech (France)', 'ror': 'https://ror.org/00dwde739', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210091113']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Jérémy Bastid', 'raw_affiliation_strings': ['OREGA Biotech, 69130 Ecully, France'], 'affiliations': [{'raw_affiliation_string': 'OREGA Biotech, 69130 Ecully, France', 'institution_ids': ['https://openalex.org/I4210091113']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003282010', 'display_name': 'François Romagné', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I21491767', 'display_name': 'Aix-Marseille Université', 'ror': 'https://ror.org/035xkbk20', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I21491767']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'François Romagné', 'raw_affiliation_strings': ['MI-mAbs, Aix Marseille Université, 117 Avenue de Luminy, 13009 Marseille, France'], 'affiliations': [{'raw_affiliation_string': 'MI-mAbs, Aix Marseille Université, 117 Avenue de Luminy, 13009 Marseille, France', 'institution_ids': ['https://openalex.org/I21491767']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064976704', 'display_name': 'Yannis Morel', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210143497', 'display_name': 'Innate Pharma (France)', 'ror': 'https://ror.org/055wa9133', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210143497']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Yannis Morel', 'raw_affiliation_strings': ['Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France'], 'affiliations': [{'raw_affiliation_string': 'Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France', 'institution_ids': ['https://openalex.org/I4210143497']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5078486100', 'display_name': 'Émilie Narni-Mancinelli', 'orcid': 'https://orcid.org/0000-0002-7001-1026'}, 'institutions': [{'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I4210144005', 'display_name': 'Centre d’Immunologie de Marseille-Luminy', 'ror': 'https://ror.org/03vyjkj45', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I21491767', 'https://openalex.org/I4210096427', 'https://openalex.org/I4210144005']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I21491767', 'display_name': 'Aix-Marseille Université', 'ror': 'https://ror.org/035xkbk20', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I21491767']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Emilie Narni-Mancinelli', 'raw_affiliation_strings': ["Aix Marseille Université, INSERM, CNRS, Centre d'Immunologie de Marseille-Luminy, 13009 Marseille, France"], 'affiliations': [{'raw_affiliation_string': "Aix Marseille Université, INSERM, CNRS, Centre d'Immunologie de Marseille-Luminy, 13009 Marseille, France", 'institution_ids': ['https://openalex.org/I154526488', 'https://openalex.org/I4210144005', 'https://openalex.org/I1294671590', 'https://openalex.org/I21491767']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023634131', 'display_name': 'Éric Vivier', 'orcid': 'https://orcid.org/0000-0001-7022-8287'}, 'institutions': [{'id': 'https://openalex.org/I4210162909', 'display_name': 'Hôpital de la Timone', 'ror': 'https://ror.org/05jrr4320', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087487', 'https://openalex.org/I4210162909']}, {'id': 'https://openalex.org/I4210087487', 'display_name': 'Assistance Publique Hôpitaux de Marseille', 'ror': 'https://ror.org/002cp4060', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087487']}, {'id': 'https://openalex.org/I4210143497', 'display_name': 'Innate Pharma (France)', 'ror': 'https://ror.org/055wa9133', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210143497']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I4210144005', 'display_name': 'Centre d’Immunologie de Marseille-Luminy', 'ror': 'https://ror.org/03vyjkj45', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I21491767', 'https://openalex.org/I4210096427', 'https://openalex.org/I4210144005']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I21491767', 'display_name': 'Aix-Marseille Université', 'ror': 'https://ror.org/035xkbk20', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I21491767']}], 'countries': ['FR'], 'is_corresponding': True, 'raw_author_name': 'Eric Vivier', 'raw_affiliation_strings': ["Aix Marseille Université, INSERM, CNRS, Centre d'Immunologie de Marseille-Luminy, 13009 Marseille, France", 'Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France', "Service d'Immunologie, Marseille Immunopôle, Hôpital de la Timone, Assistance Publique-Hôpitaux de Marseille, 13005 Marseille, France"], 'affiliations': [{'raw_affiliation_string': "Service d'Immunologie, Marseille Immunopôle, Hôpital de la Timone, Assistance Publique-Hôpitaux de Marseille, 13005 Marseille, France", 'institution_ids': ['https://openalex.org/I4210162909', 'https://openalex.org/I4210087487']}, {'raw_affiliation_string': 'Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France', 'institution_ids': ['https://openalex.org/I4210143497']}, {'raw_affiliation_string': "Aix Marseille Université, INSERM, CNRS, Centre d'Immunologie de Marseille-Luminy, 13009 Marseille, France", 'institution_ids': ['https://openalex.org/I154526488', 'https://openalex.org/I4210144005', 'https://openalex.org/I1294671590', 'https://openalex.org/I21491767']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051292571', 'display_name': 'Carine Paturel', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210143497', 'display_name': 'Innate Pharma (France)', 'ror': 'https://ror.org/055wa9133', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210143497']}], 'countries': ['FR'], 'is_corresponding': True, 'raw_author_name': 'Carine Paturel', 'raw_affiliation_strings': ['Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France'], 'affiliations': [{'raw_affiliation_string': 'Innate Pharma, 117 Avenue de Luminy, 13009 Marseille, France', 'institution_ids': ['https://openalex.org/I4210143497']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5091159789', 'display_name': 'Nathalie Bonnefoy', 'orcid': 'https://orcid.org/0000-0003-4814-6722'}, 'institutions': [{'id': 'https://openalex.org/I4210140335', 'display_name': 'Institut de Recherche en Cancérologie de Montpellier', 'ror': 'https://ror.org/03capj968', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I19894307', 'https://openalex.org/I4210137371', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210140335']}, {'id': 'https://openalex.org/I19894307', 'display_name': 'Université de Montpellier', 'ror': 'https://ror.org/051escj72', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I19894307']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': True, 'raw_author_name': 'Nathalie Bonnefoy', 'raw_affiliation_strings': ['IRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, 34298 Montpellier, France'], 'affiliations': [{'raw_affiliation_string': 'IRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, 34298 Montpellier, France', 'institution_ids': ['https://openalex.org/I4210140335', 'https://openalex.org/I19894307', 'https://openalex.org/I154526488']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 16, 'corresponding_author_ids': ['https://openalex.org/A5023634131', 'https://openalex.org/A5051292571', 'https://openalex.org/A5091159789'], 'corresponding_institution_ids': ['https://openalex.org/I4210162909', 'https://openalex.org/I4210087487', 'https://openalex.org/I4210143497', 'https://openalex.org/I154526488', 'https://openalex.org/I4210144005', 'https://openalex.org/I1294671590', 'https://openalex.org/I21491767', 'https://openalex.org/I4210143497', 'https://openalex.org/I4210140335', 'https://openalex.org/I19894307', 'https://openalex.org/I154526488'], 'apc_list': {'value': 5200, 'currency': 'USD', 'value_usd': 5200, 'provenance': 'doaj'}, 'apc_paid': {'value': 5200, 'currency': 'USD', 'value_usd': 5200, 'provenance': 'doaj'}, 'fwci': 32.511, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 339, 'citation_normalized_percentile': {'value': 0.999193, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '27', 'issue': '8', 'first_page': '2411', 'last_page': '2425.e9'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11193', 'display_name': 'Adenosine and Purinergic Signaling', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1314', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11193', 'display_name': 'Adenosine and Purinergic Signaling', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1314', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10158', 'display_name': 'Cancer Immunotherapy and Biomarkers', 'score': 0.9554, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10782', 'display_name': 'Nanoplatforms for cancer theranostics', 'score': 0.9484, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/immune-checkpoint', 'display_name': 'Immune checkpoint', 'score': 0.49917555}, {'id': 'https://openalex.org/keywords/blocking-antibody', 'display_name': 'Blocking antibody', 'score': 0.48542222}, {'id': 'https://openalex.org/keywords/cancer-immunotherapy', 'display_name': 'Cancer Immunotherapy', 'score': 0.43137833}], 'concepts': [{'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.65754765}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.603205}, {'id': 'https://openalex.org/C2776107976', 'wikidata': 'https://www.wikidata.org/wiki/Q1786433', 'display_name': 'Tumor microenvironment', 'level': 3, 'score': 0.5653189}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.5583098}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.5246544}, {'id': 'https://openalex.org/C542903549', 'wikidata': 'https://www.wikidata.org/wiki/Q422248', 'display_name': 'Monoclonal antibody', 'level': 3, 'score': 0.50275517}, {'id': 'https://openalex.org/C2780851360', 'wikidata': 'https://www.wikidata.org/wiki/Q21686041', 'display_name': 'Immune checkpoint', 'level': 4, 'score': 0.49917555}, {'id': 'https://openalex.org/C45121317', 'wikidata': 'https://www.wikidata.org/wiki/Q4927287', 'display_name': 'Blocking antibody', 'level': 3, 'score': 0.48542222}, {'id': 'https://openalex.org/C2777701055', 'wikidata': 'https://www.wikidata.org/wiki/Q1427096', 'display_name': 'Immunotherapy', 'level': 3, 'score': 0.4654722}, {'id': 'https://openalex.org/C2780674031', 'wikidata': 'https://www.wikidata.org/wiki/Q2012719', 'display_name': 'Cancer immunotherapy', 'level': 4, 'score': 0.43137833}, {'id': 'https://openalex.org/C96232424', 'wikidata': 'https://www.wikidata.org/wiki/Q4118072', 'display_name': 'Cancer cell', 'level': 3, 'score': 0.42484027}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.41939294}, {'id': 'https://openalex.org/C2776991684', 'wikidata': 'https://www.wikidata.org/wiki/Q190012', 'display_name': 'Adenosine', 'level': 2, 'score': 0.41764373}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.3982643}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.39729884}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.08179274}], 'mesh': [{'descriptor_ui': 'D015720', 'descriptor_name': "5'-Nucleotidase", 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D019138', 'descriptor_name': 'Antibodies, Blocking', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D015703', 'descriptor_name': 'Antigens, CD', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D001081', 'descriptor_name': 'Apyrase', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D015720', 'descriptor_name': "5'-Nucleotidase", 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D015720', 'descriptor_name': "5'-Nucleotidase", 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015720', 'descriptor_name': "5'-Nucleotidase", 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000241', 'descriptor_name': 'Adenosine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000241', 'descriptor_name': 'Adenosine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000255', 'descriptor_name': 'Adenosine Triphosphate', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000255', 'descriptor_name': 'Adenosine Triphosphate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019138', 'descriptor_name': 'Antibodies, Blocking', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D019138', 'descriptor_name': 'Antibodies, Blocking', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015703', 'descriptor_name': 'Antigens, CD', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015703', 'descriptor_name': 'Antigens, CD', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001081', 'descriptor_name': 'Apyrase', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001081', 'descriptor_name': 'Apyrase', 'qualifier_ui': 'Q000172', 'qualifier_name': 'deficiency', 'is_major_topic': False}, {'descriptor_ui': 'D001081', 'descriptor_name': 'Apyrase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004195', 'descriptor_name': 'Disease Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055879', 'descriptor_name': 'Gene Knock-In Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007963', 'descriptor_name': 'Leukocytes, Mononuclear', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007963', 'descriptor_name': 'Leukocytes, Mononuclear', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D007963', 'descriptor_name': 'Leukocytes, Mononuclear', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008545', 'descriptor_name': 'Melanoma', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D008545', 'descriptor_name': 'Melanoma', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D008545', 'descriptor_name': 'Melanoma', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D008545', 'descriptor_name': 'Melanoma', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D008545', 'descriptor_name': 'Melanoma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008810', 'descriptor_name': 'Mice, Inbred C57BL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018345', 'descriptor_name': 'Mice, Knockout', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077150', 'descriptor_name': 'Oxaliplatin', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D000077150', 'descriptor_name': 'Oxaliplatin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015996', 'descriptor_name': 'Survival Rate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D059016', 'descriptor_name': 'Tumor Microenvironment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 7, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.celrep.2019.04.091', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S169236886', 'display_name': 'Cell Reports', 'issn_l': '2211-1247', 'issn': ['2211-1247', '2639-1856'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hal.science/hal-02359444', 'pdf_url': 'https://hal.science/hal-02359444/document', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/5587ee70bc8c4270948f7103cc944bcd', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://hal.archives-ouvertes.fr/hal-02359444/file/Blocking%20Antibodies%20Targeting%20the%20CD39_CD73Immunosuppressive%20Pathway%20_PIIS2211124719305716.pdf', 'pdf_url': 'https://hal.archives-ouvertes.fr/hal-02359444/file/Blocking%20Antibodies%20Targeting%20the%20CD39_CD73Immunosuppressive%20Pathway%20_PIIS2211124719305716.pdf', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hal.science/hal-02359444/file/Blocking%20Antibodies%20Targeting%20the%20CD39_CD73Immunosuppressive%20Pathway%20_PIIS2211124719305716.pdf', 'pdf_url': 'https://hal.science/hal-02359444/file/Blocking%20Antibodies%20Targeting%20the%20CD39_CD73Immunosuppressive%20Pathway%20_PIIS2211124719305716.pdf', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hal.archives-ouvertes.fr/hal-02359444/document', 'pdf_url': 'https://hal.archives-ouvertes.fr/hal-02359444/document', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/31116985', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.celrep.2019.04.091', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S169236886', 'display_name': 'Cell Reports', 'issn_l': '2211-1247', 'issn': ['2211-1247', '2639-1856'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.82}], 'grants': [{'funder': 'https://openalex.org/F4320320883', 'funder_display_name': 'Agence Nationale de la Recherche', 'award_id': None}, {'funder': 'https://openalex.org/F4320321589', 'funder_display_name': 'Fondation pour la Recherche Médicale', 'award_id': None}, {'funder': 'https://openalex.org/F4320322363', 'funder_display_name': 'Ligue Contre le Cancer', 'award_id': None}, {'funder': 'https://openalex.org/F4320325941', 'funder_display_name': 'Fondation pour la Recherche Nuovo-Soldati', 'award_id': None}, {'funder': 'https://openalex.org/F4320327185', 'funder_display_name': 'French Infrastructure for Integrated Structural Biology', 'award_id': None}, {'funder': 'https://openalex.org/F4320334678', 'funder_display_name': 'European Research Council', 'award_id': '694502'}], 'datasets': [], 'versions': [], 'referenced_works_count': 53, 'referenced_works': ['https://openalex.org/W1235696336', 'https://openalex.org/W1546479459', 'https://openalex.org/W1674891863', 'https://openalex.org/W1774891022', 'https://openalex.org/W1963492398', 'https://openalex.org/W1966919402', 'https://openalex.org/W1987038396', 'https://openalex.org/W1999998145', 'https://openalex.org/W2001312442', 'https://openalex.org/W200144424', 'https://openalex.org/W2006158980', 'https://openalex.org/W2018968534', 'https://openalex.org/W2029728509', 'https://openalex.org/W2029733235', 'https://openalex.org/W2030272844', 'https://openalex.org/W2033577259', 'https://openalex.org/W2038457027', 'https://openalex.org/W2042166512', 'https://openalex.org/W2049601932', 'https://openalex.org/W2056753839', 'https://openalex.org/W2060070314', 'https://openalex.org/W2096064309', 'https://openalex.org/W2104750134', 'https://openalex.org/W2108921801', 'https://openalex.org/W2120426523', 'https://openalex.org/W2124026197', 'https://openalex.org/W2131878959', 'https://openalex.org/W2134122465', 'https://openalex.org/W2144081223', 'https://openalex.org/W2146080841', 'https://openalex.org/W2148231177', 'https://openalex.org/W2151070736', 'https://openalex.org/W2154714625', 'https://openalex.org/W2155682217', 'https://openalex.org/W2161546085', 'https://openalex.org/W2162883643', 'https://openalex.org/W2168786562', 'https://openalex.org/W2270180142', 'https://openalex.org/W2276522360', 'https://openalex.org/W2294927533', 'https://openalex.org/W2419279201', 'https://openalex.org/W2519184848', 'https://openalex.org/W2587048937', 'https://openalex.org/W2733185934', 'https://openalex.org/W2766745368', 'https://openalex.org/W2768884195', 'https://openalex.org/W2804073610', 'https://openalex.org/W2884332748', 'https://openalex.org/W2887018003', 'https://openalex.org/W2892380094', 'https://openalex.org/W2899789156', 'https://openalex.org/W4210675630', 'https://openalex.org/W4248872320'], 'related_works': ['https://openalex.org/W3216620946', 'https://openalex.org/W3205845357', 'https://openalex.org/W3095731313', 'https://openalex.org/W2902626376', 'https://openalex.org/W2401134112', 'https://openalex.org/W2161261138', 'https://openalex.org/W2055758548', 'https://openalex.org/W2022674876', 'https://openalex.org/W1973797973', 'https://openalex.org/W1946101854'], 'abstract_inverted_index': {'Immune': [0], 'checkpoint': [1, 143], 'inhibitors': [2, 144], 'have': [3], 'revolutionized': [4], 'cancer': [5, 106], 'treatment.': [6], 'However,': [7], 'many': [8], 'cancers': [9], 'are': [10], 'resistant': [11], 'to': [12, 41, 51], 'ICIs,': [13], 'and': [14, 37, 61, 66, 71, 74, 94, 96, 134, 138, 145], 'the': [15, 32, 42, 53, 77, 99, 118, 122, 130], 'targeting': [16, 63], 'of': [17, 29, 35, 44, 69, 79, 101, 121, 132], 'additional': [18], 'inhibitory': [19], 'signals': [20], 'is': [21], 'crucial': [22], 'for': [23], 'limiting': [24], 'tumor': [25, 47], 'evasion.': [26], 'The': [27], 'production': [28], 'adenosine': [30, 54], 'via': [31], 'sequential': [33], 'activity': [34, 120], 'CD39': [36, 70, 111], 'CD73': [38], 'ectoenzymes': [39], 'participates': [40], 'generation': [43], 'an': [45], 'immunosuppressive': [46, 83], 'microenvironment.': [48], 'In': [49, 108], 'order': [50], 'disrupt': [52], 'pathway,': [55], 'we': [56], 'generated': [57], 'two': [58], 'antibodies,': [59], 'IPH5201': [60, 116], 'IPH5301,': [62], 'human': [64, 110], 'membrane-associated': [65], 'soluble': [67], 'forms': [68], 'CD73,': [72], 'respectively,': [73], 'efficiently': [75], 'blocking': [76], 'hydrolysis': [78], 'immunogenic': [80], 'ATP': [81], 'into': [82], 'adenosine.': [84], 'These': [85, 127], 'antibodies': [86, 137], 'promoted': [87], 'antitumor': [88], 'immunity': [89], 'by': [90, 97], 'stimulating': [91], 'dendritic': [92], 'cells': [93, 103], 'macrophages': [95], 'restoring': [98], 'activation': [100], 'T': [102], 'isolated': [104], 'from': [105], 'patients.': [107], 'a': [109], 'knockin': [112], 'mouse': [113], 'preclinical': [114], 'model,': [115], 'increased': [117], 'anti-tumor': [119], 'ATP-inducing': [123], 'chemotherapeutic': [124], 'drug': [125], 'oxaliplatin.': [126], 'results': [128], 'support': [129], 'use': [131], 'anti-CD39': [133], 'anti-CD73': [135], 'monoclonal': [136], 'their': [139], 'combination': [140], 'with': [141], 'immune': [142], 'chemotherapies': [146], 'in': [147], 'cancer.': [148]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2945715301', 'counts_by_year': [{'year': 2024, 'cited_by_count': 45}, {'year': 2023, 'cited_by_count': 59}, {'year': 2022, 'cited_by_count': 77}, {'year': 2021, 'cited_by_count': 63}, {'year': 2020, 'cited_by_count': 64}, {'year': 2019, 'cited_by_count': 21}], 'updated_date': '2024-12-24T19:10:35.222133', 'created_date': '2019-05-29'}