Title: Mo1388 – Targeted Next Generation Sequencing for Predicting Prognosis in Endoscopic Ultrasound-Guided Fine Needle Aspirates of Pancreatic Ductal Adenocarcinoma
Abstract: 299.77 ng/ml vs 51.92 ± 29.40 ng/ml, p<0.00001 and 301.59 ± 190.36 ng/ml vs 51.92 ± 29.40 ng/ml, p<0.00001).IGFBP-2 in CP without DM was also higher compared to those with PDAC and without DM (559.39 ± 281.43 vs 296.53 ± 196.93, p=0.00001).Conclusions: IGF-1 and IGFBP-2 are good biomarkers of pancreatic diseases, especially CP and PDAC.Elevated levels of IGF-1 in the course of CP may indicate the presence of pancreatic cyst.IGF-1 may be an indicator which signals whether pancreatic diabetes comes from CP or PDAC.Further studies are necessary to examine if this biomarker will be able to differentiate pancreatic diabetes as a first symptom of PDAC. Mo1386