Publication Information

{'id': 'https://openalex.org/W2944027287', 'doi': 'https://doi.org/10.1038/s41467-019-09904-5', 'title': 'Asymmetric synthesis of tetrazole and dihydroisoquinoline derivatives by isocyanide-based multicomponent reactions', 'display_name': 'Asymmetric synthesis of tetrazole and dihydroisoquinoline derivatives by isocyanide-based multicomponent reactions', 'publication_year': 2019, 'publication_date': '2019-05-09', 'ids': {'openalex': 'https://openalex.org/W2944027287', 'doi': 'https://doi.org/10.1038/s41467-019-09904-5', 'mag': '2944027287', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/31073191', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6509109'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/s41467-019-09904-5', 'pdf_url': 'https://www.nature.com/articles/s41467-019-09904-5.pdf', 'source': {'id': 'https://openalex.org/S64187185', 'display_name': 'Nature Communications', 'issn_l': '2041-1723', 'issn': ['2041-1723'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.nature.com/articles/s41467-019-09904-5.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5035119933', 'display_name': 'Qian Xiong', 'orcid': 'https://orcid.org/0000-0003-3140-959X'}, 'institutions': [{'id': 'https://openalex.org/I24185976', 'display_name': 'Sichuan University', 'ror': 'https://ror.org/011ashp19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24185976']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Qian Xiong', 'raw_affiliation_strings': ['Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, China'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, China', 'institution_ids': ['https://openalex.org/I24185976']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081426782', 'display_name': 'Shunxi Dong', 'orcid': 'https://orcid.org/0000-0002-3018-3085'}, 'institutions': [{'id': 'https://openalex.org/I24185976', 'display_name': 'Sichuan University', 'ror': 'https://ror.org/011ashp19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24185976']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Shunxi Dong', 'raw_affiliation_strings': ['Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, China'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, China', 'institution_ids': ['https://openalex.org/I24185976']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5009853550', 'display_name': 'Yushuang Chen', 'orcid': 'https://orcid.org/0000-0003-4157-8709'}, 'institutions': [{'id': 'https://openalex.org/I24185976', 'display_name': 'Sichuan University', 'ror': 'https://ror.org/011ashp19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24185976']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yushuang Chen', 'raw_affiliation_strings': ['Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, China'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, China', 'institution_ids': ['https://openalex.org/I24185976']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100370781', 'display_name': 'Xiaohua Liu', 'orcid': 'https://orcid.org/0000-0001-9555-0555'}, 'institutions': [{'id': 'https://openalex.org/I24185976', 'display_name': 'Sichuan University', 'ror': 'https://ror.org/011ashp19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24185976']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiaohua Liu', 'raw_affiliation_strings': ['Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, China'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, China', 'institution_ids': ['https://openalex.org/I24185976']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5077217676', 'display_name': 'Xiaoming Feng', 'orcid': 'https://orcid.org/0000-0003-4507-0478'}, 'institutions': [{'id': 'https://openalex.org/I24185976', 'display_name': 'Sichuan University', 'ror': 'https://ror.org/011ashp19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24185976']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiaoming Feng', 'raw_affiliation_strings': ['Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, China'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, China', 'institution_ids': ['https://openalex.org/I24185976']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3920, 'currency': 'GBP', 'value_usd': 4808, 'provenance': 'doaj'}, 'apc_paid': {'value': 3920, 'currency': 'GBP', 'value_usd': 4808, 'provenance': 'doaj'}, 'fwci': 5.038, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 72, 'citation_normalized_percentile': {'value': 0.999938, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '10', 'issue': '1', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10817', 'display_name': 'Multicomponent Synthesis of Heterocycles', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/1605', 'display_name': 'Organic Chemistry'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10817', 'display_name': 'Multicomponent Synthesis of Heterocycles', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/1605', 'display_name': 'Organic Chemistry'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T13265', 'display_name': 'Synthesis of Tetrazole Derivatives', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/1605', 'display_name': 'Organic Chemistry'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T12318', 'display_name': 'Quinazolinone synthesis and applications', 'score': 0.992, 'subfield': {'id': 'https://openalex.org/subfields/1605', 'display_name': 'Organic Chemistry'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/tetrazole', 'display_name': 'Tetrazole', 'score': 0.8298696}, {'id': 'https://openalex.org/keywords/annulation', 'display_name': 'Annulation', 'score': 0.51856786}, {'id': 'https://openalex.org/keywords/malonate', 'display_name': 'Malonate', 'score': 0.42618376}], 'concepts': [{'id': 'https://openalex.org/C2777010268', 'wikidata': 'https://www.wikidata.org/wiki/Q421897', 'display_name': 'Isocyanide', 'level': 2, 'score': 0.9049409}, {'id': 'https://openalex.org/C146686406', 'wikidata': 'https://www.wikidata.org/wiki/Q898628', 'display_name': 'Enantioselective synthesis', 'level': 3, 'score': 0.8347746}, {'id': 'https://openalex.org/C2780827033', 'wikidata': 'https://www.wikidata.org/wiki/Q58826308', 'display_name': 'Tetrazole', 'level': 2, 'score': 0.8298696}, {'id': 'https://openalex.org/C21951064', 'wikidata': 'https://www.wikidata.org/wiki/Q899212', 'display_name': 'Combinatorial chemistry', 'level': 1, 'score': 0.6399195}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.6379531}, {'id': 'https://openalex.org/C161790260', 'wikidata': 'https://www.wikidata.org/wiki/Q82264', 'display_name': 'Catalysis', 'level': 2, 'score': 0.6046782}, {'id': 'https://openalex.org/C7512685', 'wikidata': 'https://www.wikidata.org/wiki/Q529093', 'display_name': 'Annulation', 'level': 3, 'score': 0.51856786}, {'id': 'https://openalex.org/C116569031', 'wikidata': 'https://www.wikidata.org/wiki/Q899107', 'display_name': 'Ligand (biochemistry)', 'level': 3, 'score': 0.49768475}, {'id': 'https://openalex.org/C2777552763', 'wikidata': 'https://www.wikidata.org/wiki/Q421972', 'display_name': 'Malonate', 'level': 2, 'score': 0.42618376}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.32688367}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/s41467-019-09904-5', 'pdf_url': 'https://www.nature.com/articles/s41467-019-09904-5.pdf', 'source': {'id': 'https://openalex.org/S64187185', 'display_name': 'Nature Communications', 'issn_l': '2041-1723', 'issn': ['2041-1723'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/acf4f00c9b424b08a7574e6fbe6e3a44', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc6509109', 'pdf_url': 'https://europepmc.org/articles/pmc6509109?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509109', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/31073191', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/s41467-019-09904-5', 'pdf_url': 'https://www.nature.com/articles/s41467-019-09904-5.pdf', 'source': {'id': 'https://openalex.org/S64187185', 'display_name': 'Nature Communications', 'issn_l': '2041-1723', 'issn': ['2041-1723'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.45, 'display_name': 'Clean water and sanitation', 'id': 'https://metadata.un.org/sdg/6'}], 'grants': [], 'datasets': ['https://openalex.org/W4397348252', 'https://openalex.org/W4397490442', 'https://openalex.org/W4397749570'], 'versions': [], 'referenced_works_count': 47, 'referenced_works': ['https://openalex.org/W1501906745', 'https://openalex.org/W1837315762', 'https://openalex.org/W1978749374', 'https://openalex.org/W1981047084', 'https://openalex.org/W2022926519', 'https://openalex.org/W2034380051', 'https://openalex.org/W2042043797', 'https://openalex.org/W2059523269', 'https://openalex.org/W2077074100', 'https://openalex.org/W2080428771', 'https://openalex.org/W2086805350', 'https://openalex.org/W2112146567', 'https://openalex.org/W2125282956', 'https://openalex.org/W2126974923', 'https://openalex.org/W2127378043', 'https://openalex.org/W2127909394', 'https://openalex.org/W2144442575', 'https://openalex.org/W2146372261', 'https://openalex.org/W2152680780', 'https://openalex.org/W2158548106', 'https://openalex.org/W2159259582', 'https://openalex.org/W2239429815', 'https://openalex.org/W2299655782', 'https://openalex.org/W2324559824', 'https://openalex.org/W2330733209', 'https://openalex.org/W2336836584', 'https://openalex.org/W2400537560', 'https://openalex.org/W2407040666', 'https://openalex.org/W2470271646', 'https://openalex.org/W2502246907', 'https://openalex.org/W2526216986', 'https://openalex.org/W2565275889', 'https://openalex.org/W2576276560', 'https://openalex.org/W2746872199', 'https://openalex.org/W2762238273', 'https://openalex.org/W2802088792', 'https://openalex.org/W2883416535', 'https://openalex.org/W2890446973', 'https://openalex.org/W2892158053', 'https://openalex.org/W2949244907', 'https://openalex.org/W2949383687', 'https://openalex.org/W2950092368', 'https://openalex.org/W2951688887', 'https://openalex.org/W2951991302', 'https://openalex.org/W2952504242', 'https://openalex.org/W2953225867', 'https://openalex.org/W592757206'], 'related_works': ['https://openalex.org/W4362594116', 'https://openalex.org/W4318820457', 'https://openalex.org/W3125492253', 'https://openalex.org/W2998759773', 'https://openalex.org/W2998223762', 'https://openalex.org/W2951344012', 'https://openalex.org/W2921265200', 'https://openalex.org/W2897063804', 'https://openalex.org/W2509220222', 'https://openalex.org/W1996598134'], 'abstract_inverted_index': {'Abstract': [0], 'Although': [1], 'isocyanide-based': [2, 51], 'multicomponent': [3, 52], 'reactions': [4, 53, 84], 'were': [5], 'proven': [6], 'to': [7, 26, 47, 101, 155], 'be': [8, 86], 'simple,': [9], 'elegant': [10], 'and': [11, 78, 112], 'facile': [12], 'strategies': [13], 'for': [14], 'the': [15, 41, 57, 71, 113], 'synthesis': [16], 'of': [17, 44, 59, 96, 116, 132, 145], 'highly': [18], 'valuable': [19], 'nitrogen-containing': [20], 'heterocycles,': [21], 'their': [22], 'asymmetric': [23], 'versions': [24], 'accessing': [25], 'optically': [27], 'active': [28], 'nitrogen': [29], 'heterocyclic': [30], 'compounds': [31], 'are': [32, 54, 123], 'rather': [33], 'limited.': [34], 'Here,': [35], 'we': [36], 'illustrate': [37], 'that,': [38], 'relying': [39], 'on': [40, 126], 'enantioselective': [42, 140], 'addition': [43], 'simple': [45], 'isocyanides': [46], 'C=C': [48], 'bonds,': [49], 'several': [50], 'realized': [55], 'in': [56, 99, 153], 'presence': [58], 'a': [60, 108, 137], 'chiral': [61, 151], 'Mg': [62], 'II': [63], '-': [64], 'N': [65, 67], ',': [66, 77], 'ʹ-dioxide': [68], 'catalyst.': [69], 'In': [70], 'reaction': [72, 91, 144], 'among': [73], 'isocyanide,': [74], 'TMSN': [75], '3': [76], 'alkylidene': [79], 'malonate,': [80], 'three-': [81], 'or': [82, 120], 'four-component': [83], 'could': [85], 'precisely': [87], 'controlled': [88], 'by': [89], 'modulating': [90], 'conditions,': [92], 'supplying': [93], 'two': [94], 'types': [95], 'enantioenriched': [97], 'tetrazole-derivatives': [98], 'moderate': [100], 'high': [102], 'yields.': [103], 'Possible': [104], 'catalytic': [105], 'cycles': [106], 'via': [107], 'key': [109], 'zwitterionic': [110, 134], 'intermediate,': [111], 'vital': [114], 'roles': [115], 'H': [117], '2': [118], 'O': [119], 'excess': [121], 'ligand': [122], 'provided': [124], 'based': [125], 'control': [127], 'experiments.': [128], 'Moreover,': [129], 'taking': [130], 'advantage': [131], 'this': [133], 'intermediate': [135], 'as': [136], '1,3-dipole,': [138], 'an': [139], 'dearomative': [141], '[3+2]': [142], 'annulation': [143], 'nonactivated': [146], 'isoquinolines': [147], 'is': [148], 'achieved,': [149], 'furnishing': [150], '1,2-dihydroisoquinolines': [152], 'good': [154], 'excellent': [156], 'results.': [157]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2944027287', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 13}, {'year': 2022, 'cited_by_count': 14}, {'year': 2021, 'cited_by_count': 17}, {'year': 2020, 'cited_by_count': 17}, {'year': 2019, 'cited_by_count': 5}], 'updated_date': '2024-12-16T14:38:00.524433', 'created_date': '2019-05-16'}