Publication Information

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'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W67732338', 'https://openalex.org/W3140102804', 'https://openalex.org/W3036349246', 'https://openalex.org/W2956186113', 'https://openalex.org/W2945924635', 'https://openalex.org/W2803560915', 'https://openalex.org/W2799473390', 'https://openalex.org/W2587113693', 'https://openalex.org/W2564349670', 'https://openalex.org/W2548752869', 'https://openalex.org/W2517169372', 'https://openalex.org/W2152451724', 'https://openalex.org/W2128928935', 'https://openalex.org/W2112154638', 'https://openalex.org/W2110750414', 'https://openalex.org/W2065872061', 'https://openalex.org/W2048750724', 'https://openalex.org/W2038968759', 'https://openalex.org/W1978212707', 'https://openalex.org/W1970709974'], 'abstract_inverted_index': {'Clopidogrel': [0], 'therapy': [1], 'in': [2, 11, 43, 74, 87, 121, 152, 157, 174, 187, 191, 206, 229], 'combination': [3, 122, 192, 214], 'with': [4, 65, 90, 123, 177, 193], 'proton': [5], 'pump': [6], 'inhibitors': [7], '(PPIs)': [8], 'is': [9, 70, 85, 125, 172, 200], 'controversial': [10], 'the': [12, 30, 44, 55, 75, 112, 142, 196, 209, 213, 227], 'treatment': [13, 93], 'for': [14, 94], 'ischemic': [15], 'heart': [16], 'diseases': [17], 'after': [18], 'coronary': [19], 'stent': [20], 'implantation': [21], 'because': [22], 'PPIs': [23], '(especially': [24], 'omeprazole)': [25], 'are': [26, 223], 'suggested': [27], 'to': [28, 127, 182, 208, 225], 'attenuate': [29], 'antiplatelet': [31, 143], 'effect': [32, 144], 'of': [33, 46, 57, 62, 132, 145, 198, 215], 'clopidogrel.': [34, 218], 'The': [35, 60, 78, 116], 'polymorphic': [36], 'CYP2C19': [37, 58, 63, 83, 100, 167, 170, 210], 'enzyme': [38], 'has': [39], 'a': [40, 66, 128, 137], 'pivotal': [41], 'function': [42], 'metabolism': [45], 'both': [47], 'agents.': [48], 'In': [49, 102], 'addition,': [50], 'omeprazole': [51, 92, 120, 151, 179, 216], 'can': [52], 'irreversibly': [53], 'inhibit': [54], 'activity': 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'Interestingly,': [141], 'more': [148], 'affected': [149], 'by': [150], 'homozygous': [153, 163], 'CYP2C19*1': [154], 'carries': [155], 'than': [156], 'heterozygous': [158], '(*1/2': [159], 'or': [160, 165], '*1/3)': [161], '(*2/2': [164], '*2/3)': [166], 'carriers.': [168], 'Therefore,': [169], 'advised': [173], 'treatment.': [180], 'This': [181], 'prevent': [183], 'treated': [189], 'PPIs.': [194], 'However,': [195], 'number': [197], 'studies': [199, 222], 'rather': [201], 'limited': [202], 'up': [203], 'till': [204], 'now': [205], 'relation': [207], 'status': [211], 'plus': [217], 'Therefore': [219], 'further': [220], 'clinical': [221], 'indispensable': [224], 'verify': [226], 'conclusion': [228], 'study.': [231]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2942385418', 'counts_by_year': [], 'updated_date': '2024-12-07T01:45:26.425248', 'created_date': '2019-05-03'}