Publication Information

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'cyanide': [35, 69, 119, 138, 151, 312], 'yielding': [36], 'thiosulfate': [37], 'the': [39, 101, 150, 184, 208, 250, 275], 'non-toxic': [40], 'compound': [41], 'thiocyanate.': [42], 'Thiosulfate,': [43], 'turn,': [45], 'neutralizes': [46, 57], 'second': [48], 'molecule': [49], 'of': [50, 60, 95, 103, 117, 128, 183, 235, 249, 289, 292, 310], 'cyanide,': [51], 'thus,': [52], 'per': [53], 'mole,': [54], 'sodium': [55, 105, 160, 209, 226, 293], 'two': [58], 'moles': [59], 'cyanide.': [61], 'Historical': [62], 'studies': [63], 'examined': [64], 'its': [65], 'efficacy': [66, 102], 'as': [67], 'antidote,': [70, 239], 'but': [71, 242], 'it': [72, 86], 'has': [73, 85], 'not': [74], 'been': [75, 88], 'evaluated': [76, 174], 'clinically': [79], 'relevant,': [80], 'large': [81], 'animal': [82], 'model,': [83], 'nor': [84], 'previously': [87], 'administered': [89], 'by': [90], 'intramuscular': [91, 104, 290], 'injection.Objective:': [92], 'The': [93, 269], 'objective': [94], 'this': [96], 'study': [97], 'to': [99, 136, 195, 229, 272], 'evaluate': [100], 'on': [107], 'survival': [108, 301], 'clinical': [110, 303], 'outcomes': [111, 304], 'large,': [114, 307], 'swine': [115, 122, 308], 'model': [116, 309], 'severe': [118], 'toxicity.Methods:': [120], 'Anesthetized': [121], 'were': [123, 157, 173, 197, 295], 'instrumented': [124], 'for': [125, 147], 'continuous': [126], 'monitoring': [127], 'hemodynamics,': [129], 'then': [130], 'acclimated': [131], 'breathing': [133, 230], 'spontaneously': [134], 'prior': [135], 'potassium': [137], 'infusion': [139, 152], '(0.17': [140], 'mg/kg/min).': [141], 'At': [142], '6-min': [143], 'post-apnea': [144], '(no': [145], 'breaths': [146], '20': [148], 's),': [149], 'was': [153, 213], 'terminated,': [154], 'animals': [156, 223], 'treated': [158, 211, 224, 253], '(∼18': [162], 'mg/kg)': [163], 'or': [164, 181, 285], 'normal': [165], 'saline': [166], 'control.': [167], 'Clinical': [168], 'parameters': [169], 'laboratory': [171], 'values': [172], 'at': [175, 202, 231, 265], 'various': [176], 'time': [177, 194, 234, 271], 'points': [178], 'until': [179], 'death': [180, 273], 'termination': [182], 'experiment': [185], '(90': [186], 'min': [187, 237, 267], 'post-treatment).Results:': [188], 'Laboratory': [189], 'values,': [190], 'vital': [191], 'signs,': [192], 'apnea': [196], 'similar': [198], 'both': [200], 'groups': [201], 'baseline': [203], 'treatment.': [205], 'Survival': [206], 'group': [212, 277], '100%': [214], '17%': [216], 'controls': [218], '(p': [219, 261], '=': [220], '0.0043).': [221], 'All': [222], 'returned': [228], 'mean': [233], '10.85': [236], 'after': [238], 'all': [241], 'one': [243], 'control': [244, 276], 'remained': [245], 'apneic': [246], 'through': [247], 'end': [248], 'experiment.': [251], 'Animals': [252], 'showed': [256], 'improvement': [257], 'blood': [259], 'lactate': [260], '≤': [262], '0.002)': [263], 'starting': [264], '30': [266], 'post-treatment.': [268], 'average': [270], '63.3': [279], '±': [280], '23.2': [281], 'min.': [282], 'No': [283], 'systemic': [284], 'localized': [286], 'adverse': [287], 'effects': [288], 'administration': [291], 'observed.Conclusion:': [296], 'significantly': [299], 'improves': [300], 'acute': [311], 'poisoning.': [313]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2941920870', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 4}], 'updated_date': '2025-01-15T20:22:57.852837', 'created_date': '2019-05-03'}