Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2940459858', 'doi': 'https://doi.org/10.1093/eurheartj/ehz202', 'title': 'Platelet reactivity and clinical outcomes in acute coronary syndrome patients treated with prasugrel and clopidogrel: a pre-specified exploratory analysis from the TROPICAL-ACS trial', 'display_name': 'Platelet reactivity and clinical outcomes in acute coronary syndrome patients treated with prasugrel and clopidogrel: a pre-specified exploratory analysis from the TROPICAL-ACS trial', 'publication_year': 2019, 'publication_date': '2019-04-17', 'ids': {'openalex': 'https://openalex.org/W2940459858', 'doi': 'https://doi.org/10.1093/eurheartj/ehz202', 'mag': '2940459858', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/31226213'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1093/eurheartj/ehz202', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S181568219', 'display_name': 'European Heart Journal', 'issn_l': '0195-668X', 'issn': ['0195-668X', '1522-9645'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5012467226', 'display_name': 'Dániel Aradi', 'orcid': 'https://orcid.org/0000-0003-1833-2516'}, 'institutions': [{'id': 'https://openalex.org/I101202996', 'display_name': 'Semmelweis University', 'ror': 'https://ror.org/01g9ty582', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I101202996']}], 'countries': ['HU'], 'is_corresponding': False, 'raw_author_name': 'Dániel Aradi', 'raw_affiliation_strings': ['Department of Active Cardiology, Heart Centre Balatonfüred and Heart and Vascular Centre, Semmelweis University Budapest, 2 Gyógy Tér, Balatonfüred, Hungary', 'Department of Cardiology, Heart and Vascular Centre, Semmelweis University Budapest, Budapest, Hungary'], 'affiliations': [{'raw_affiliation_string': 'Department of Active Cardiology, Heart Centre Balatonfüred and Heart and Vascular Centre, Semmelweis University Budapest, 2 Gyógy Tér, Balatonfüred, Hungary', 'institution_ids': ['https://openalex.org/I101202996']}, {'raw_affiliation_string': 'Department of Cardiology, Heart and Vascular Centre, Semmelweis University Budapest, Budapest, Hungary', 'institution_ids': ['https://openalex.org/I101202996']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5032412677', 'display_name': 'Lisa Groß', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210127591', 'display_name': 'German Centre for Cardiovascular Research', 'ror': 'https://ror.org/031t5w623', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I4210127591']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Lisa Gross', 'raw_affiliation_strings': ['Partner Site Munich Heart Alliance, DZHK (German Center for Cardiovascular Research), Munich, Germany'], 'affiliations': [{'raw_affiliation_string': 'Partner Site Munich Heart Alliance, DZHK (German Center for Cardiovascular Research), Munich, Germany', 'institution_ids': ['https://openalex.org/I4210127591', 'https://openalex.org/I4210127591']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068846586', 'display_name': 'Dietmar Trenk', 'orcid': 'https://orcid.org/0000-0003-0505-7121'}, 'institutions': [{'id': 'https://openalex.org/I4210133302', 'display_name': 'Universitäts-Herzzentrum Freiburg-Bad Krozingen', 'ror': 'https://ror.org/02w6m7e50', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210133302']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Dietmar Trenk', 'raw_affiliation_strings': ['Department of Cardiology and Angiology II, University Heart Centre Freiburg-Bad Krozingen, Bad Krozingen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology and Angiology II, University Heart Centre Freiburg-Bad Krozingen, Bad Krozingen, Germany', 'institution_ids': ['https://openalex.org/I4210133302']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090714953', 'display_name': 'Tobias Geisler', 'orcid': 'https://orcid.org/0000-0002-8864-6038'}, 'institutions': [{'id': 'https://openalex.org/I4210125796', 'display_name': "University Children's Hospital Tübingen", 'ror': 'https://ror.org/03esvmb28', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210094118', 'https://openalex.org/I4210125796']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Tobias Geisler', 'raw_affiliation_strings': ['Department of Cardiology and Cardiovascular Disease, University Hospital Tübingen, Tübingen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology and Cardiovascular Disease, University Hospital Tübingen, Tübingen, Germany', 'institution_ids': ['https://openalex.org/I4210125796']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086692319', 'display_name': 'Béla Merkely', 'orcid': 'https://orcid.org/0000-0001-6514-0723'}, 'institutions': [{'id': 'https://openalex.org/I101202996', 'display_name': 'Semmelweis University', 'ror': 'https://ror.org/01g9ty582', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I101202996']}], 'countries': ['HU'], 'is_corresponding': False, 'raw_author_name': 'Béla Merkely', 'raw_affiliation_strings': ['Department of Cardiology, Heart and Vascular Centre, Semmelweis University Budapest, Budapest, Hungary'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology, Heart and Vascular Centre, Semmelweis University Budapest, Budapest, Hungary', 'institution_ids': ['https://openalex.org/I101202996']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015803547', 'display_name': 'Róbert Gábor Kiss', 'orcid': 'https://orcid.org/0000-0003-0514-7530'}, 'institutions': [], 'countries': ['HU'], 'is_corresponding': False, 'raw_author_name': 'Róbert Gábor Kiss', 'raw_affiliation_strings': ['Department of Cardiology, Military Hospital, Budapest, Hungary'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology, Military Hospital, Budapest, Hungary', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073075473', 'display_name': 'András Komócsi', 'orcid': 'https://orcid.org/0000-0002-8170-1778'}, 'institutions': [{'id': 'https://openalex.org/I79741316', 'display_name': 'University of Pecs', 'ror': 'https://ror.org/037b5pv06', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I79741316']}], 'countries': ['HU'], 'is_corresponding': False, 'raw_author_name': 'András Komócsi', 'raw_affiliation_strings': ['Department of Interventional Cardiology, Heart Institute, University of Pécs, Pécs, Hungary'], 'affiliations': [{'raw_affiliation_string': 'Department of Interventional Cardiology, Heart Institute, University of Pécs, Pécs, Hungary', 'institution_ids': ['https://openalex.org/I79741316']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070827922', 'display_name': 'Csaba András Dézsi', 'orcid': 'https://orcid.org/0000-0002-7203-0423'}, 'institutions': [{'id': 'https://openalex.org/I4210146066', 'display_name': 'Petz Aladár Megyei Oktató Kórház', 'ror': 'https://ror.org/03vqk1b90', 'country_code': 'HU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210146066']}], 'countries': ['HU'], 'is_corresponding': False, 'raw_author_name': 'Csaba András Dézsi', 'raw_affiliation_strings': ['Department of Cardiology, Petz Aladár County Hospital Győr, Győr, Hungary'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology, Petz Aladár County Hospital Győr, Győr, Hungary', 'institution_ids': ['https://openalex.org/I4210146066']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023974390', 'display_name': 'Zoltán Ruzsa', 'orcid': 'https://orcid.org/0000-0002-2474-5723'}, 'institutions': [{'id': 'https://openalex.org/I101202996', 'display_name': 'Semmelweis University', 'ror': 'https://ror.org/01g9ty582', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I101202996']}], 'countries': ['HU'], 'is_corresponding': False, 'raw_author_name': 'Zoltán Ruzsa', 'raw_affiliation_strings': ['Department of Cardiology, Heart and Vascular Centre, Semmelweis University Budapest, Budapest, Hungary'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology, Heart and Vascular Centre, Semmelweis University Budapest, Budapest, Hungary', 'institution_ids': ['https://openalex.org/I101202996']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008587276', 'display_name': 'Imre Ungi', 'orcid': 'https://orcid.org/0000-0002-2011-0069'}, 'institutions': [{'id': 'https://openalex.org/I227486990', 'display_name': 'University of Szeged', 'ror': 'https://ror.org/01pnej532', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I227486990']}], 'countries': ['HU'], 'is_corresponding': False, 'raw_author_name': 'Imre Ungi', 'raw_affiliation_strings': ['Department of Cardiology, University of Szeged, Szeged, Hungary'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology, University of Szeged, Szeged, Hungary', 'institution_ids': ['https://openalex.org/I227486990']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039734287', 'display_name': 'Konstantinos D. Rizas', 'orcid': 'https://orcid.org/0000-0002-5993-0339'}, 'institutions': [{'id': 'https://openalex.org/I4210127591', 'display_name': 'German Centre for Cardiovascular Research', 'ror': 'https://ror.org/031t5w623', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I4210127591']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Konstantinos D Rizas', 'raw_affiliation_strings': ['Partner Site Munich Heart Alliance, DZHK (German Center for Cardiovascular Research), Munich, Germany'], 'affiliations': [{'raw_affiliation_string': 'Partner Site Munich Heart Alliance, DZHK (German Center for Cardiovascular Research), Munich, Germany', 'institution_ids': ['https://openalex.org/I4210127591', 'https://openalex.org/I4210127591']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111635076', 'display_name': 'Andreas E. May', 'orcid': None}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Andreas E May', 'raw_affiliation_strings': ['Department of Cardiology, Innere Medizin I, Klinikum Memmingen, Memmingen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology, Innere Medizin I, Klinikum Memmingen, Memmingen, Germany', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5043893807', 'display_name': 'Andreas Mügge', 'orcid': 'https://orcid.org/0000-0001-9548-6995'}, 'institutions': [{'id': 'https://openalex.org/I4210153564', 'display_name': 'Katholisches Klinikum Bochum', 'ror': 'https://ror.org/05k5t2r42', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153564']}, {'id': 'https://openalex.org/I4210138993', 'display_name': 'St. Josef-Hospital', 'ror': 'https://ror.org/046vare28', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799784675', 'https://openalex.org/I4210138993', 'https://openalex.org/I4210153564']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Andreas Mügge', 'raw_affiliation_strings': ['Department of Cardiology, Katholisches Klinikum Bochum, St. Josef Hospital, Bochum, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology, Katholisches Klinikum Bochum, St. Josef Hospital, Bochum, Germany', 'institution_ids': ['https://openalex.org/I4210153564', 'https://openalex.org/I4210138993']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061907666', 'display_name': 'Andreas M. Zeiher', 'orcid': 'https://orcid.org/0000-0003-1711-5819'}, 'institutions': [{'id': 'https://openalex.org/I4210132578', 'display_name': 'University Hospital Frankfurt', 'ror': 'https://ror.org/03f6n9m15', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210132578']}, {'id': 'https://openalex.org/I114090438', 'display_name': 'Goethe University Frankfurt', 'ror': 'https://ror.org/04cvxnb49', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I114090438']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Andreas M Zeiher', 'raw_affiliation_strings': ['Department of Cardiology, Universitätsklinikum Frankfurt, Frankfurt/Main, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology, Universitätsklinikum Frankfurt, Frankfurt/Main, Germany', 'institution_ids': ['https://openalex.org/I4210132578', 'https://openalex.org/I114090438']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5024120001', 'display_name': 'Lesca M. Holdt', 'orcid': 'https://orcid.org/0000-0001-5735-4975'}, 'institutions': [{'id': 'https://openalex.org/I3018771216', 'display_name': 'LMU Klinikum', 'ror': 'https://ror.org/02jet3w32', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3018771216', 'https://openalex.org/I8204097']}, {'id': 'https://openalex.org/I8204097', 'display_name': 'Ludwig-Maximilians-Universität München', 'ror': 'https://ror.org/05591te55', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I8204097']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Lesca Holdt', 'raw_affiliation_strings': ['Institute of Laboratory Medicine, University Hospital, LMU Munich, Munich, Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Laboratory Medicine, University Hospital, LMU Munich, Munich, Germany', 'institution_ids': ['https://openalex.org/I3018771216', 'https://openalex.org/I8204097']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077862111', 'display_name': 'Kurt Huber', 'orcid': 'https://orcid.org/0000-0002-7934-5524'}, 'institutions': [{'id': 'https://openalex.org/I109570744', 'display_name': 'Sigmund Freud University Vienna', 'ror': 'https://ror.org/04hwbg047', 'country_code': 'AT', 'type': 'education', 'lineage': ['https://openalex.org/I109570744']}], 'countries': ['AT'], 'is_corresponding': False, 'raw_author_name': 'Kurt Huber', 'raw_affiliation_strings': ['3rd Medical Department, Cardiology and Intensive Care Medicine, Sigmund Freud Private University, Medical School, Wien, Austria'], 'affiliations': [{'raw_affiliation_string': '3rd Medical Department, Cardiology and Intensive Care Medicine, Sigmund Freud Private University, Medical School, Wien, Austria', 'institution_ids': ['https://openalex.org/I109570744']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005201146', 'display_name': 'Franz‐Josef Neumann', 'orcid': 'https://orcid.org/0000-0002-9478-2757'}, 'institutions': [{'id': 'https://openalex.org/I4210133302', 'display_name': 'Universitäts-Herzzentrum Freiburg-Bad Krozingen', 'ror': 'https://ror.org/02w6m7e50', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210133302']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Franz-Josef Neumann', 'raw_affiliation_strings': ['Department of Cardiology and Angiology II, University Heart Centre Freiburg-Bad Krozingen, Bad Krozingen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology and Angiology II, University Heart Centre Freiburg-Bad Krozingen, Bad Krozingen, Germany', 'institution_ids': ['https://openalex.org/I4210133302']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063780377', 'display_name': 'Łukasz Kołtowski', 'orcid': 'https://orcid.org/0000-0003-0477-2094'}, 'institutions': [{'id': 'https://openalex.org/I268303160', 'display_name': 'Medical University of Warsaw', 'ror': 'https://ror.org/04p2y4s44', 'country_code': 'PL', 'type': 'education', 'lineage': ['https://openalex.org/I268303160']}], 'countries': ['PL'], 'is_corresponding': False, 'raw_author_name': 'Lukasz Koltowski', 'raw_affiliation_strings': ['1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland'], 'affiliations': [{'raw_affiliation_string': '1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland', 'institution_ids': ['https://openalex.org/I268303160']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5076996249', 'display_name': 'Zenon Huczek', 'orcid': 'https://orcid.org/0000-0002-5912-2649'}, 'institutions': [{'id': 'https://openalex.org/I268303160', 'display_name': 'Medical University of Warsaw', 'ror': 'https://ror.org/04p2y4s44', 'country_code': 'PL', 'type': 'education', 'lineage': ['https://openalex.org/I268303160']}], 'countries': ['PL'], 'is_corresponding': False, 'raw_author_name': 'Zenon Huczek', 'raw_affiliation_strings': ['1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland'], 'affiliations': [{'raw_affiliation_string': '1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland', 'institution_ids': ['https://openalex.org/I268303160']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039606590', 'display_name': 'Martin Hadamitzky', 'orcid': 'https://orcid.org/0000-0001-6267-1692'}, 'institutions': [{'id': 'https://openalex.org/I4210148371', 'display_name': 'Deutsches Herzzentrum München', 'ror': 'https://ror.org/04hbwba26', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210148371', 'https://openalex.org/I62916508']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Martin Hadamitzky', 'raw_affiliation_strings': ['Department of Radiology and Nuclear Medicine, Deutsches Herzzentrum München, Munich, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiology and Nuclear Medicine, Deutsches Herzzentrum München, Munich, Germany', 'institution_ids': ['https://openalex.org/I4210148371']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007093669', 'display_name': 'Steffen Maßberg', 'orcid': 'https://orcid.org/0000-0001-7387-3986'}, 'institutions': [{'id': 'https://openalex.org/I4210127591', 'display_name': 'German Centre for Cardiovascular Research', 'ror': 'https://ror.org/031t5w623', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I4210127591']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Steffen Massberg', 'raw_affiliation_strings': ['Partner Site Munich Heart Alliance, DZHK (German Center for Cardiovascular Research), Munich, Germany'], 'affiliations': [{'raw_affiliation_string': 'Partner Site Munich Heart Alliance, DZHK (German Center for Cardiovascular Research), Munich, Germany', 'institution_ids': ['https://openalex.org/I4210127591', 'https://openalex.org/I4210127591']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5078073832', 'display_name': 'Dirk Sibbing', 'orcid': 'https://orcid.org/0000-0002-0698-2696'}, 'institutions': [{'id': 'https://openalex.org/I4210127591', 'display_name': 'German Centre for Cardiovascular Research', 'ror': 'https://ror.org/031t5w623', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I4210127591']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Dirk Sibbing', 'raw_affiliation_strings': ['Partner Site Munich Heart Alliance, DZHK (German Center for Cardiovascular Research), Munich, Germany'], 'affiliations': [{'raw_affiliation_string': 'Partner Site Munich Heart Alliance, DZHK (German Center for Cardiovascular Research), Munich, Germany', 'institution_ids': ['https://openalex.org/I4210127591', 'https://openalex.org/I4210127591']}]}], 'institution_assertions': [], 'countries_distinct_count': 4, 'institutions_distinct_count': 16, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4238, 'currency': 'EUR', 'value_usd': 4570, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 6.036, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 47, 'citation_normalized_percentile': {'value': 0.99996, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '40', 'issue': '24', 'first_page': '1942', 'last_page': '1951'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11064', 'display_name': 'Antiplatelet Therapy and Cardiovascular Diseases', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11064', 'display_name': 'Antiplatelet Therapy and Cardiovascular Diseases', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10292', 'display_name': 'Acute Myocardial Infarction Research', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10065', 'display_name': 'Atrial Fibrillation Management and Outcomes', 'score': 0.9975, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2777028646', 'wikidata': 'https://www.wikidata.org/wiki/Q416232', 'display_name': 'Prasugrel', 'level': 4, 'score': 0.99375117}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.92730796}, {'id': 'https://openalex.org/C2777849778', 'wikidata': 'https://www.wikidata.org/wiki/Q410237', 'display_name': 'Clopidogrel', 'level': 3, 'score': 0.89716333}, {'id': 'https://openalex.org/C2777698277', 'wikidata': 'https://www.wikidata.org/wiki/Q266018', 'display_name': 'Acute coronary syndrome', 'level': 3, 'score': 0.7171117}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.6182102}, {'id': 'https://openalex.org/C164705383', 'wikidata': 'https://www.wikidata.org/wiki/Q10379', 'display_name': 'Cardiology', 'level': 1, 'score': 0.46611363}, {'id': 'https://openalex.org/C500558357', 'wikidata': 'https://www.wikidata.org/wiki/Q12152', 'display_name': 'Myocardial infarction', 'level': 2, 'score': 0.43921548}, {'id': 'https://openalex.org/C168563851', 'wikidata': 'https://www.wikidata.org/wiki/Q1436668', 'display_name': 'Randomized controlled trial', 'level': 2, 'score': 0.4193054}, {'id': 'https://openalex.org/C207103383', 'wikidata': 'https://www.wikidata.org/wiki/Q3930246', 'display_name': 'Hazard ratio', 'level': 3, 'score': 0.4170714}, {'id': 'https://openalex.org/C49059817', 'wikidata': 'https://www.wikidata.org/wiki/Q14916330', 'display_name': 'P2Y12', 'level': 4, 'score': 0.41267878}, {'id': 'https://openalex.org/C44249647', 'wikidata': 'https://www.wikidata.org/wiki/Q208498', 'display_name': 'Confidence interval', 'level': 2, 'score': 0.11049694}], 'mesh': [{'descriptor_ui': 'D054058', 'descriptor_name': 'Acute Coronary Syndrome', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D001792', 'descriptor_name': 'Blood Platelets', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D000077144', 'descriptor_name': 'Clopidogrel', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D010975', 'descriptor_name': 'Platelet Aggregation Inhibitors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000068799', 'descriptor_name': 'Prasugrel Hydrochloride', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D054058', 'descriptor_name': 'Acute Coronary Syndrome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001792', 'descriptor_name': 'Blood Platelets', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016022', 'descriptor_name': 'Case-Control Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077144', 'descriptor_name': 'Clopidogrel', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077144', 'descriptor_name': 'Clopidogrel', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D000077144', 'descriptor_name': 'Clopidogrel', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D003643', 'descriptor_name': 'Death', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004359', 'descriptor_name': 'Drug Therapy, Combination', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004359', 'descriptor_name': 'Drug Therapy, Combination', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006470', 'descriptor_name': 'Hemorrhage', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D006470', 'descriptor_name': 'Hemorrhage', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': False}, {'descriptor_ui': 'D006470', 'descriptor_name': 'Hemorrhage', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007511', 'descriptor_name': 'Ischemia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007511', 'descriptor_name': 'Ischemia', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': False}, {'descriptor_ui': 'D007511', 'descriptor_name': 'Ischemia', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009203', 'descriptor_name': 'Myocardial Infarction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009203', 'descriptor_name': 'Myocardial Infarction', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': False}, {'descriptor_ui': 'D010975', 'descriptor_name': 'Platelet Aggregation Inhibitors', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D010975', 'descriptor_name': 'Platelet Aggregation Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010975', 'descriptor_name': 'Platelet Aggregation Inhibitors', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D010979', 'descriptor_name': 'Platelet Function Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010979', 'descriptor_name': 'Platelet Function Tests', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D000068799', 'descriptor_name': 'Prasugrel Hydrochloride', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000068799', 'descriptor_name': 'Prasugrel Hydrochloride', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D000068799', 'descriptor_name': 'Prasugrel Hydrochloride', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D018570', 'descriptor_name': 'Risk Assessment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020521', 'descriptor_name': 'Stroke', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020521', 'descriptor_name': 'Stroke', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1093/eurheartj/ehz202', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S181568219', 'display_name': 'European Heart Journal', 'issn_l': '0195-668X', 'issn': ['0195-668X', '1522-9645'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/31226213', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.84}], 'grants': [{'funder': 'https://openalex.org/F4320307770', 'funder_display_name': 'AstraZeneca', 'award_id': None}, {'funder': 'https://openalex.org/F4320333988', 'funder_display_name': 'Roche Diagnostics', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 31, 'referenced_works': ['https://openalex.org/W144700851', 'https://openalex.org/W1972809452', 'https://openalex.org/W1985059672', 'https://openalex.org/W1990018236', 'https://openalex.org/W2012369487', 'https://openalex.org/W2018234502', 'https://openalex.org/W2052106438', 'https://openalex.org/W2091687606', 'https://openalex.org/W2108817878', 'https://openalex.org/W2121205446', 'https://openalex.org/W2140501627', 'https://openalex.org/W2145323902', 'https://openalex.org/W2147675498', 'https://openalex.org/W2155545321', 'https://openalex.org/W2157833432', 'https://openalex.org/W2161785946', 'https://openalex.org/W2164386459', 'https://openalex.org/W2169387542', 'https://openalex.org/W2509918966', 'https://openalex.org/W2510902864', 'https://openalex.org/W2526988450', 'https://openalex.org/W2598689766', 'https://openalex.org/W2748517697', 'https://openalex.org/W2752033985', 'https://openalex.org/W2766257307', 'https://openalex.org/W2780411499', 'https://openalex.org/W2788079067', 'https://openalex.org/W2792364309', 'https://openalex.org/W2887919176', 'https://openalex.org/W2916912835', 'https://openalex.org/W3140387310'], 'related_works': ['https://openalex.org/W4287010319', 'https://openalex.org/W3207761463', 'https://openalex.org/W3185809790', 'https://openalex.org/W2753219180', 'https://openalex.org/W2418485858', 'https://openalex.org/W2412620152', 'https://openalex.org/W2158537546', 'https://openalex.org/W2115826049', 'https://openalex.org/W2060841228', 'https://openalex.org/W1534422272'], 'abstract_inverted_index': {'The': [0, 98], 'value': [1], 'of': [2, 21, 256, 275, 307, 319], 'platelet': [3, 34, 39, 250, 311], 'function': [4], 'testing': [5], '(PFT)': [6], 'in': [7, 44, 153, 165, 186, 205, 237, 287], 'predicting': [8], 'clinical': [9], 'outcomes': [10, 183, 290], 'and': [11, 28, 37, 88, 140, 203, 316, 324], 'guiding': [12], 'P2Y12-inhibitor': [13], 'treatment': [14, 79, 91, 147], 'is': [15], 'uncertain.': [16], 'In': [17, 223], 'a': [18, 231, 276, 314], 'pre-specified': [19], 'sub-study': [20], 'the': [22, 138, 143, 154], 'TROPICAL-ACS': [23], 'trial,': [24, 278], 'we': [25], 'assessed': [26], 'ischaemic': [27, 100, 235, 289, 308], 'bleeding': [29, 257, 320], 'risks': [30], 'according': [31], 'to': [32, 42, 70, 86, 94, 137, 142, 172, 212], 'high': [33], 'reactivity': [35, 40, 251, 312], '(HPR)': [36], 'low': [38], '(LPR)': [41], 'ADP': [43], 'patients': [45, 56, 129, 167, 174, 188, 206, 239], 'receiving': [46], 'uniform': [47, 71, 292], 'prasugrel': [48, 72, 85, 178, 213, 227, 280, 293, 301, 323], 'vs.': [49, 81, 158, 169], 'PFT-guided': [50, 89], 'clopidogrel': [51, 87, 191, 210, 282], 'or': [52, 107, 281], 'prasugrel.Acute': [53], 'coronary': [54], 'syndrome': [55], 'with': [57, 67, 130, 207, 230, 304], 'PFT': [58, 122, 131, 285], 'done': [59], '14': [60], 'days': [61], 'after': [62], 'hospital': [63], 'discharge': [64], 'were': [65, 135, 184], 'included': [66, 102], 'prior': [68], 'randomization': [69], 'for': [73, 234], '12': [74, 124], 'months': [75], '(control': [76], 'group,': [77], 'no': [78], 'modification)': [80], 'early': [82], 'de-escalation': [83], 'from': [84, 121], 'maintenance': [90], '(HPR:': [92], 'switch-back': [93], 'prasugrel,': [95], 'non-HPR:': [96], 'clopidogrel).': [97], 'composite': [99], 'endpoint': [101], 'cardiovascular': [103], 'death,': [104], 'myocardial': [105], 'infarction,': [106], 'stroke,': [108], 'while': [109, 160], 'key': [110], 'safety': [111], 'outcome': [112], 'was': [113, 150, 162, 228, 252, 302, 313], 'Bleeding': [114], 'Academic': [115], 'Research': [116], 'Consortium': [117], '(BARC)': [118], '2-5': [119], 'bleeding,': [120], 'until': [123], 'months.': [125], 'We': [126], 'identified': [127], '2527': [128], 'results': [132], 'available:': [133], '1266': [134], 'randomized': [136, 277], 'guided': [139, 155, 187], '1261': [141], 'control': [144, 166, 173, 238], 'group.': [145], 'Before': [146], 'adjustment,': [148], 'HPR': [149, 176, 208, 225, 299], 'more': [151, 163], 'prevalent': [152], 'group': [156], '(40%': [157], '15%),': [159], 'LPR': [161], 'common': [164], '(27%': [168], '11%).': [170], 'Compared': [171], 'without': [175, 264, 295], 'on': [177, 190, 209, 226, 272, 284, 300, 322], '(n': [179], '=': [180, 193, 201, 215, 221, 241, 247, 262, 267], '1073),': [181], 'similar': [182, 288], 'observed': [185], 'kept': [189], '[n': [192, 214, 240], '755,': [194], 'hazard': [195], 'ratio': [196], '(HR):': [197], '1.06': [198], '(0.57-1.95),': [199], 'P': [200, 220, 246, 261], '0.86]': [202], 'also': [204], 'switched': [211], '511,': [216], 'HR:': [217, 243], '0.96': [218], '(0.47-1.96),': [219], '0.91].': [222], 'contrast,': [224], 'associated': [229, 303], 'higher': [232], 'risk': [233, 306], 'events': [236], '188,': [242], '2.16': [244], '(1.01-4.65),': [245], '0.049].': [248], 'Low': [249, 310], 'an': [253], 'independent': [254, 317], 'predictor': [255, 318], '[HR:': [258], '1.74': [259], '(1.18-2.56),': [260], '0.005],': [263], 'interaction': [265], '(Pint': [266], '0.76)': [268], 'between': [269], 'study': [270], 'groups.Based': [271], 'this': [273], 'substudy': [274], 'selecting': [279], 'based': [283], 'resulted': [286], 'as': [291], 'therapy': [294], 'HPR.': [296], 'Although': [297], 'infrequent,': [298], 'increased': [305], 'events.': [309], 'strong': [315], 'both': [321], 'clopidogrel.': [325]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2940459858', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 8}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 9}, {'year': 2020, 'cited_by_count': 9}, {'year': 2019, 'cited_by_count': 12}], 'updated_date': '2024-12-09T19:47:23.691948', 'created_date': '2019-05-03'}