Publication Information

{'id': 'https://openalex.org/W2940220885', 'doi': 'https://doi.org/10.1016/j.celrep.2019.03.054', 'title': 'Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism', 'display_name': 'Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism', 'publication_year': 2019, 'publication_date': '2019-04-01', 'ids': {'openalex': 'https://openalex.org/W2940220885', 'doi': 'https://doi.org/10.1016/j.celrep.2019.03.054', 'mag': '2940220885', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/30995474'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.celrep.2019.03.054', 'pdf_url': 'https://www.cell.com/article/S2211124719303845/pdf', 'source': {'id': 'https://openalex.org/S169236886', 'display_name': 'Cell Reports', 'issn_l': '2211-1247', 'issn': ['2211-1247', '2639-1856'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.cell.com/article/S2211124719303845/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5013949680', 'display_name': 'José Luís Fachi', 'orcid': 'https://orcid.org/0000-0002-1035-5193'}, 'institutions': [{'id': 'https://openalex.org/I181391015', 'display_name': 'Universidade Estadual de Campinas (UNICAMP)', 'ror': 'https://ror.org/04wffgt70', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I181391015']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'José Luís Fachi', 'raw_affiliation_strings': ['Laboratory of Immunoinflammation, Department of Genetics, Evolution, Microbiology, and Immunology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunoinflammation, Department of Genetics, Evolution, Microbiology, and Immunology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil', 'institution_ids': ['https://openalex.org/I181391015']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052347564', 'display_name': 'Jaqueline de Souza Felipe', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I181391015', 'display_name': 'Universidade Estadual de Campinas (UNICAMP)', 'ror': 'https://ror.org/04wffgt70', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I181391015']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Jaqueline de Souza Felipe', 'raw_affiliation_strings': ['Laboratory of Immunoinflammation, Department of Genetics, Evolution, Microbiology, and Immunology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunoinflammation, Department of Genetics, Evolution, Microbiology, and Immunology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil', 'institution_ids': ['https://openalex.org/I181391015']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083976560', 'display_name': 'Laís Passariello Pral', 'orcid': 'https://orcid.org/0000-0002-3008-0465'}, 'institutions': [{'id': 'https://openalex.org/I181391015', 'display_name': 'Universidade Estadual de Campinas (UNICAMP)', 'ror': 'https://ror.org/04wffgt70', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I181391015']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Laís Passariello Pral', 'raw_affiliation_strings': ['Laboratory of Immunoinflammation, Department of Genetics, Evolution, Microbiology, and Immunology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunoinflammation, Department of Genetics, Evolution, Microbiology, and Immunology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil', 'institution_ids': ['https://openalex.org/I181391015']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039822358', 'display_name': 'Bruna Karadi da Silva', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I181391015', 'display_name': 'Universidade Estadual de Campinas (UNICAMP)', 'ror': 'https://ror.org/04wffgt70', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I181391015']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Bruna Karadi da Silva', 'raw_affiliation_strings': ['Laboratory of Immunoinflammation, Department of Genetics, Evolution, Microbiology, and Immunology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunoinflammation, Department of Genetics, Evolution, Microbiology, and Immunology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil', 'institution_ids': ['https://openalex.org/I181391015']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088955841', 'display_name': 'Renan Oliveira Corrêa', 'orcid': 'https://orcid.org/0000-0002-3333-0482'}, 'institutions': [{'id': 'https://openalex.org/I181391015', 'display_name': 'Universidade Estadual de Campinas (UNICAMP)', 'ror': 'https://ror.org/04wffgt70', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I181391015']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Renan Oliveira Corrêa', 'raw_affiliation_strings': ['Laboratory of Immunoinflammation, Department of Genetics, Evolution, Microbiology, and Immunology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunoinflammation, Department of Genetics, Evolution, Microbiology, and Immunology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil', 'institution_ids': ['https://openalex.org/I181391015']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110957278', 'display_name': 'Mirella Cristiny Pereira de Andrade', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I181391015', 'display_name': 'Universidade Estadual de Campinas (UNICAMP)', 'ror': 'https://ror.org/04wffgt70', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I181391015']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Mirella Cristiny Pereira de Andrade', 'raw_affiliation_strings': ['Laboratory of Immunoinflammation, Department of Genetics, Evolution, Microbiology, and Immunology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunoinflammation, Department of Genetics, Evolution, Microbiology, and Immunology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil', 'institution_ids': ['https://openalex.org/I181391015']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037024228', 'display_name': 'Denise Morais da Fonseca', 'orcid': 'https://orcid.org/0000-0001-8310-0186'}, 'institutions': [{'id': 'https://openalex.org/I17974374', 'display_name': 'Universidade de São Paulo', 'ror': 'https://ror.org/036rp1748', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I17974374']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Denise Morais da Fonseca', 'raw_affiliation_strings': ['Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-900, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-900, Brazil', 'institution_ids': ['https://openalex.org/I17974374']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052999467', 'display_name': 'Paulo José Basso', 'orcid': 'https://orcid.org/0000-0003-4856-9207'}, 'institutions': [{'id': 'https://openalex.org/I17974374', 'display_name': 'Universidade de São Paulo', 'ror': 'https://ror.org/036rp1748', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I17974374']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Paulo José Basso', 'raw_affiliation_strings': ['Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-900, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-900, Brazil', 'institution_ids': ['https://openalex.org/I17974374']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063347657', 'display_name': 'Niels Olsen Saraiva Câmara', 'orcid': 'https://orcid.org/0000-0001-5436-1248'}, 'institutions': [{'id': 'https://openalex.org/I17974374', 'display_name': 'Universidade de São Paulo', 'ror': 'https://ror.org/036rp1748', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I17974374']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Niels Olsen Saraiva Câmara', 'raw_affiliation_strings': ['Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-900, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-900, Brazil', 'institution_ids': ['https://openalex.org/I17974374']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5078190789', 'display_name': 'Éricka Lorenna de Sales e Souza', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I110200422', 'display_name': 'Universidade Federal de Minas Gerais', 'ror': 'https://ror.org/0176yjw32', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I110200422']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Éricka Lorenna de Sales e Souza', 'raw_affiliation_strings': ['Laboratory of Biotherapeutics Agents, Department of Microbiology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, MG 31270-901, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Biotherapeutics Agents, Department of Microbiology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, MG 31270-901, Brazil', 'institution_ids': ['https://openalex.org/I110200422']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047427352', 'display_name': 'Flaviano S. Martins', 'orcid': 'https://orcid.org/0000-0003-0741-3062'}, 'institutions': [{'id': 'https://openalex.org/I110200422', 'display_name': 'Universidade Federal de Minas Gerais', 'ror': 'https://ror.org/0176yjw32', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I110200422']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Flaviano dos Santos Martins', 'raw_affiliation_strings': ['Laboratory of Biotherapeutics Agents, Department of Microbiology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, MG 31270-901, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Biotherapeutics Agents, Department of Microbiology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, MG 31270-901, Brazil', 'institution_ids': ['https://openalex.org/I110200422']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5078395043', 'display_name': 'Suzana Eiko Sato Guima', 'orcid': 'https://orcid.org/0000-0002-1031-1764'}, 'institutions': [{'id': 'https://openalex.org/I17974374', 'display_name': 'Universidade de São Paulo', 'ror': 'https://ror.org/036rp1748', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I17974374']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Suzana Eiko Sato Guima', 'raw_affiliation_strings': ['Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, SP 05508-000, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, SP 05508-000, Brazil', 'institution_ids': ['https://openalex.org/I17974374']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081300089', 'display_name': 'Andrew Maltez Thomas', 'orcid': 'https://orcid.org/0000-0001-5789-3354'}, 'institutions': [{'id': 'https://openalex.org/I17974374', 'display_name': 'Universidade de São Paulo', 'ror': 'https://ror.org/036rp1748', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I17974374']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Andrew Maltez Thomas', 'raw_affiliation_strings': ['Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, SP 05508-000, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, SP 05508-000, Brazil', 'institution_ids': ['https://openalex.org/I17974374']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060418877', 'display_name': 'João Carlos Setúbal', 'orcid': 'https://orcid.org/0000-0001-9174-2816'}, 'institutions': [{'id': 'https://openalex.org/I859038795', 'display_name': 'Virginia Tech', 'ror': 'https://ror.org/02smfhw86', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I859038795']}, {'id': 'https://openalex.org/I4210151352', 'display_name': 'Biocom', 'ror': 'https://ror.org/03ymdxs56', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210151352']}, {'id': 'https://openalex.org/I17974374', 'display_name': 'Universidade de São Paulo', 'ror': 'https://ror.org/036rp1748', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I17974374']}], 'countries': ['BR', 'US'], 'is_corresponding': False, 'raw_author_name': 'João Carlos Setubal', 'raw_affiliation_strings': ['Biocomplexity Institute, Virginia Polytechnic Institute, Blacksburg, VA 24061, USA', 'Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, SP 05508-000, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Biocomplexity Institute, Virginia Polytechnic Institute, Blacksburg, VA 24061, USA', 'institution_ids': ['https://openalex.org/I859038795', 'https://openalex.org/I4210151352']}, {'raw_affiliation_string': 'Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, SP 05508-000, Brazil', 'institution_ids': ['https://openalex.org/I17974374']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049162453', 'display_name': 'Yuli Thamires Magalhães', 'orcid': 'https://orcid.org/0000-0002-3140-5532'}, 'institutions': [{'id': 'https://openalex.org/I17974374', 'display_name': 'Universidade de São Paulo', 'ror': 'https://ror.org/036rp1748', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I17974374']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Yuli Thamires Magalhães', 'raw_affiliation_strings': ['Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, SP 05508-000, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, SP 05508-000, Brazil', 'institution_ids': ['https://openalex.org/I17974374']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089651035', 'display_name': 'Fábio Luís Forti', 'orcid': 'https://orcid.org/0000-0002-2278-6396'}, 'institutions': [{'id': 'https://openalex.org/I17974374', 'display_name': 'Universidade de São Paulo', 'ror': 'https://ror.org/036rp1748', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I17974374']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Fábio Luis Forti', 'raw_affiliation_strings': ['Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, SP 05508-000, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, SP 05508-000, Brazil', 'institution_ids': ['https://openalex.org/I17974374']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061580671', 'display_name': 'Thamiris Candreva', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I181391015', 'display_name': 'Universidade Estadual de Campinas (UNICAMP)', 'ror': 'https://ror.org/04wffgt70', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I181391015']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Thamiris Candreva', 'raw_affiliation_strings': ['Laboratory of Nutrients and Tissue Repair, School of Applied Sciences, University of Campinas, Limeira, SP 13484-350, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Nutrients and Tissue Repair, School of Applied Sciences, University of Campinas, Limeira, SP 13484-350, Brazil', 'institution_ids': ['https://openalex.org/I181391015']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036874404', 'display_name': 'Hosana Gomes Rodrigues', 'orcid': 'https://orcid.org/0000-0002-6122-0379'}, 'institutions': [{'id': 'https://openalex.org/I181391015', 'display_name': 'Universidade Estadual de Campinas (UNICAMP)', 'ror': 'https://ror.org/04wffgt70', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I181391015']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Hosana Gomes Rodrigues', 'raw_affiliation_strings': ['Laboratory of Nutrients and Tissue Repair, School of Applied Sciences, University of Campinas, Limeira, SP 13484-350, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Nutrients and Tissue Repair, School of Applied Sciences, University of Campinas, Limeira, SP 13484-350, Brazil', 'institution_ids': ['https://openalex.org/I181391015']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013139407', 'display_name': 'Marcelo Bispo de Jesus', 'orcid': 'https://orcid.org/0000-0003-0812-1491'}, 'institutions': [{'id': 'https://openalex.org/I181391015', 'display_name': 'Universidade Estadual de Campinas (UNICAMP)', 'ror': 'https://ror.org/04wffgt70', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I181391015']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Marcelo Bispo de Jesus', 'raw_affiliation_strings': ['Nano-Cell Interactions Lab, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Nano-Cell Interactions Lab, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil', 'institution_ids': ['https://openalex.org/I181391015']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018705027', 'display_name': 'Sílvio Roberto Consonni', 'orcid': 'https://orcid.org/0000-0003-3149-021X'}, 'institutions': [{'id': 'https://openalex.org/I181391015', 'display_name': 'Universidade Estadual de Campinas (UNICAMP)', 'ror': 'https://ror.org/04wffgt70', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I181391015']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Sílvio Roberto Consonni', 'raw_affiliation_strings': ['Laboratory of Citochemistry and Immunocitochemistry, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Citochemistry and Immunocitochemistry, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil', 'institution_ids': ['https://openalex.org/I181391015']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034710546', 'display_name': 'Alessandro S. Farias', 'orcid': 'https://orcid.org/0000-0001-6759-1819'}, 'institutions': [{'id': 'https://openalex.org/I181391015', 'display_name': 'Universidade Estadual de Campinas (UNICAMP)', 'ror': 'https://ror.org/04wffgt70', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I181391015']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Alessandro dos Santos Farias', 'raw_affiliation_strings': ['Laboratory of Neuroimmunology, Department of Genetics, Evolution Microbiology, and Immunology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Neuroimmunology, Department of Genetics, Evolution Microbiology, and Immunology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil', 'institution_ids': ['https://openalex.org/I181391015']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036301404', 'display_name': 'Patrick Varga‐Weisz', 'orcid': 'https://orcid.org/0000-0001-7409-8686'}, 'institutions': [{'id': 'https://openalex.org/I1302113299', 'display_name': 'Babraham Institute', 'ror': 'https://ror.org/01d5qpn59', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I1302113299', 'https://openalex.org/I2799693246', 'https://openalex.org/I4210087105']}, {'id': 'https://openalex.org/I110002522', 'display_name': 'University of Essex', 'ror': 'https://ror.org/02nkf1q06', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I110002522']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Patrick Varga-Weisz', 'raw_affiliation_strings': ['Nuclear Dynamics Programme, Babraham Institute, Cambridge CB22 3AT, UK', 'School of Biological Sciences, University of Essex, Colchester CO4 3SQ, UK'], 'affiliations': [{'raw_affiliation_string': 'Nuclear Dynamics Programme, Babraham Institute, Cambridge CB22 3AT, UK', 'institution_ids': ['https://openalex.org/I1302113299']}, {'raw_affiliation_string': 'School of Biological Sciences, University of Essex, Colchester CO4 3SQ, UK', 'institution_ids': ['https://openalex.org/I110002522']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5026984796', 'display_name': 'Marco Aurélio Ramirez Vinolo', 'orcid': 'https://orcid.org/0000-0003-1335-760X'}, 'institutions': [{'id': 'https://openalex.org/I181391015', 'display_name': 'Universidade Estadual de Campinas (UNICAMP)', 'ror': 'https://ror.org/04wffgt70', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I181391015']}], 'countries': ['BR'], 'is_corresponding': True, 'raw_author_name': 'Marco Aurélio Ramirez Vinolo', 'raw_affiliation_strings': ['Laboratory of Immunoinflammation, Department of Genetics, Evolution, Microbiology, and Immunology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunoinflammation, Department of Genetics, Evolution, Microbiology, and Immunology, Institute of Biology, University of Campinas, Campinas, SP 13083-862, Brazil', 'institution_ids': ['https://openalex.org/I181391015']}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 7, 'corresponding_author_ids': ['https://openalex.org/A5026984796'], 'corresponding_institution_ids': ['https://openalex.org/I181391015'], 'apc_list': {'value': 5200, 'currency': 'USD', 'value_usd': 5200, 'provenance': 'doaj'}, 'apc_paid': {'value': 5200, 'currency': 'USD', 'value_usd': 5200, 'provenance': 'doaj'}, 'fwci': 23.821, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 265, 'citation_normalized_percentile': {'value': 0.999921, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '27', 'issue': '3', 'first_page': '750', 'last_page': '761.e7'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11288', 'display_name': 'Clostridium difficile and Clostridium perfringens research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11288', 'display_name': 'Clostridium difficile and Clostridium perfringens research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10066', 'display_name': 'Gut microbiota and health', 'score': 0.9914, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10365', 'display_name': 'Gastrointestinal motility and disorders', 'score': 0.9687, 'subfield': {'id': 'https://openalex.org/subfields/2715', 'display_name': 'Gastroenterology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/dysbiosis', 'display_name': 'Dysbiosis', 'score': 0.67344195}, {'id': 'https://openalex.org/keywords/barrier-function', 'display_name': 'Barrier function', 'score': 0.5913958}], 'concepts': [{'id': 'https://openalex.org/C2776979534', 'wikidata': 'https://www.wikidata.org/wiki/Q193213', 'display_name': 'Butyrate', 'level': 3, 'score': 0.8583665}, {'id': 'https://openalex.org/C2777165150', 'wikidata': 'https://www.wikidata.org/wiki/Q269334', 'display_name': 'Dysbiosis', 'level': 3, 'score': 0.67344195}, {'id': 'https://openalex.org/C2775862500', 'wikidata': 'https://www.wikidata.org/wiki/Q2453464', 'display_name': 'Colitis', 'level': 2, 'score': 0.6536448}, {'id': 'https://openalex.org/C2994496256', 'wikidata': 'https://www.wikidata.org/wiki/Q27031090', 'display_name': 'Clostridium difficile', 'level': 3, 'score': 0.6389462}, {'id': 'https://openalex.org/C51911345', 'wikidata': 'https://www.wikidata.org/wiki/Q4863604', 'display_name': 'Barrier function', 'level': 2, 'score': 0.5913958}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.55619925}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.48529786}, {'id': 'https://openalex.org/C134193097', 'wikidata': 'https://www.wikidata.org/wiki/Q5135489', 'display_name': 'Clostridium difficile toxin B', 'level': 5, 'score': 0.472263}, {'id': 'https://openalex.org/C97505648', 'wikidata': 'https://www.wikidata.org/wiki/Q5135488', 'display_name': 'Clostridium difficile toxin A', 'level': 4, 'score': 0.4582339}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.3871379}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3844645}, {'id': 'https://openalex.org/C501593827', 'wikidata': 'https://www.wikidata.org/wiki/Q12187', 'display_name': 'Antibiotics', 'level': 2, 'score': 0.3614143}, {'id': 'https://openalex.org/C539455810', 'wikidata': 'https://www.wikidata.org/wiki/Q739734', 'display_name': 'Gut flora', 'level': 2, 'score': 0.29975998}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.20542365}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.07309672}, {'id': 'https://openalex.org/C100544194', 'wikidata': 'https://www.wikidata.org/wiki/Q41760', 'display_name': 'Fermentation', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002087', 'descriptor_name': 'Butyrates', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D016360', 'descriptor_name': 'Clostridioides difficile', 'qualifier_ui': 'Q000472', 'qualifier_name': 'pathogenicity', 'is_major_topic': True}, {'descriptor_ui': 'D003092', 'descriptor_name': 'Colitis', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': True}, {'descriptor_ui': 'D051793', 'descriptor_name': 'Hypoxia-Inducible Factor 1', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000284', 'descriptor_name': 'Administration, Oral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D002087', 'descriptor_name': 'Butyrates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002087', 'descriptor_name': 'Butyrates', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D016360', 'descriptor_name': 'Clostridioides difficile', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016360', 'descriptor_name': 'Clostridioides difficile', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D003092', 'descriptor_name': 'Colitis', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D003092', 'descriptor_name': 'Colitis', 'qualifier_ui': 'Q000382', 'qualifier_name': 'microbiology', 'is_major_topic': False}, {'descriptor_ui': 'D003092', 'descriptor_name': 'Colitis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004847', 'descriptor_name': 'Epithelial Cells', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D004847', 'descriptor_name': 'Epithelial Cells', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004847', 'descriptor_name': 'Epithelial Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004847', 'descriptor_name': 'Epithelial Cells', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D005232', 'descriptor_name': 'Fatty Acids, Volatile', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005232', 'descriptor_name': 'Fatty Acids, Volatile', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051793', 'descriptor_name': 'Hypoxia-Inducible Factor 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007328', 'descriptor_name': 'Insulin', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D007328', 'descriptor_name': 'Insulin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007413', 'descriptor_name': 'Intestinal Mucosa', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D007413', 'descriptor_name': 'Intestinal Mucosa', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D007413', 'descriptor_name': 'Intestinal Mucosa', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008810', 'descriptor_name': 'Mice, Inbred C57BL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D064307', 'descriptor_name': 'Microbiota', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D064307', 'descriptor_name': 'Microbiota', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010539', 'descriptor_name': 'Permeability', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D010539', 'descriptor_name': 'Permeability', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019108', 'descriptor_name': 'Tight Junctions', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D019108', 'descriptor_name': 'Tight Junctions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014118', 'descriptor_name': 'Toxins, Biological', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': False}, {'descriptor_ui': 'D014118', 'descriptor_name': 'Toxins, Biological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014280', 'descriptor_name': 'Triglycerides', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D014280', 'descriptor_name': 'Triglycerides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.celrep.2019.03.054', 'pdf_url': 'https://www.cell.com/article/S2211124719303845/pdf', 'source': {'id': 'https://openalex.org/S169236886', 'display_name': 'Cell Reports', 'issn_l': '2211-1247', 'issn': ['2211-1247', '2639-1856'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/9c4fc043dfbe4f37bba8f567ccb37dd6', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'http://hdl.handle.net/10919/93202', 'pdf_url': 'https://vtechworks.lib.vt.edu/bitstream/10919/93202/1/1-s2.0-S2211124719303845-main.pdf', 'source': {'id': 'https://openalex.org/S4306400248', 'display_name': 'VTechWorks (Virginia Tech)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I859038795', 'host_organization_name': 'Virginia Tech', 'host_organization_lineage': ['https://openalex.org/I859038795'], 'host_organization_lineage_names': ['Virginia Tech'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://repository.essex.ac.uk/24651/1/1s20S2211124719303845main.pdf', 'pdf_url': 'http://repository.essex.ac.uk/24651/1/1s20S2211124719303845main.pdf', 'source': {'id': 'https://openalex.org/S4306401237', 'display_name': 'Open Access at Essex (University of Essex)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I110002522', 'host_organization_name': 'University of Essex', 'host_organization_lineage': ['https://openalex.org/I110002522'], 'host_organization_lineage_names': ['University of Essex'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/30995474', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.celrep.2019.03.054', 'pdf_url': 'https://www.cell.com/article/S2211124719303845/pdf', 'source': {'id': 'https://openalex.org/S169236886', 'display_name': 'Cell Reports', 'issn_l': '2211-1247', 'issn': ['2211-1247', '2639-1856'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320320006', 'funder_display_name': 'Royal Society', 'award_id': None}, {'funder': 'https://openalex.org/F4320320997', 'funder_display_name': 'Fundação de Amparo à Pesquisa do Estado de São Paulo', 'award_id': '2018/01753-6'}, {'funder': 'https://openalex.org/F4320320997', 'funder_display_name': 'Fundação de Amparo à Pesquisa do Estado de São Paulo', 'award_id': '2013/06810-4'}, {'funder': 'https://openalex.org/F4320320997', 'funder_display_name': 'Fundação de Amparo à Pesquisa do Estado de São Paulo', 'award_id': '2017/16280-3'}, {'funder': 'https://openalex.org/F4320320997', 'funder_display_name': 'Fundação de Amparo à Pesquisa do Estado de São Paulo', 'award_id': '2012/10653-9'}, {'funder': 'https://openalex.org/F4320320997', 'funder_display_name': 'Fundação de Amparo à Pesquisa do Estado de São Paulo', 'award_id': '2014/03002-7'}, {'funder': 'https://openalex.org/F4320320997', 'funder_display_name': 'Fundação de Amparo à Pesquisa do Estado de São Paulo', 'award_id': '2015/06134-4'}, {'funder': 'https://openalex.org/F4320321091', 'funder_display_name': 'Coordenação de Aperfeiçoamento de Pessoal de Nível Superior', 'award_id': None}, {'funder': 'https://openalex.org/F4320322025', 'funder_display_name': 'Conselho Nacional de Desenvolvimento Científico e Tecnológico', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 54, 'referenced_works': ['https://openalex.org/W1948266836', 'https://openalex.org/W1973650764', 'https://openalex.org/W1974603596', 'https://openalex.org/W1979012796', 'https://openalex.org/W1981266729', 'https://openalex.org/W1981884436', 'https://openalex.org/W1982920345', 'https://openalex.org/W1984771489', 'https://openalex.org/W1988925586', 'https://openalex.org/W1992174684', 'https://openalex.org/W1993830991', 'https://openalex.org/W1998016881', 'https://openalex.org/W2001938165', 'https://openalex.org/W2003342633', 'https://openalex.org/W2003481369', 'https://openalex.org/W2007247918', 'https://openalex.org/W2008294135', 'https://openalex.org/W2021800929', 'https://openalex.org/W2030129318', 'https://openalex.org/W2036897871', 'https://openalex.org/W2039062534', 'https://openalex.org/W2060185417', 'https://openalex.org/W2072970694', 'https://openalex.org/W2079183971', 'https://openalex.org/W2083096979', 'https://openalex.org/W2088833470', 'https://openalex.org/W2096436144', 'https://openalex.org/W2104318549', 'https://openalex.org/W2105329815', 'https://openalex.org/W2115717127', 'https://openalex.org/W2119522619', 'https://openalex.org/W2121180999', 'https://openalex.org/W2127067932', 'https://openalex.org/W2148171446', 'https://openalex.org/W2153109441', 'https://openalex.org/W2153333049', 'https://openalex.org/W2160125244', 'https://openalex.org/W2165067288', 'https://openalex.org/W2170024099', 'https://openalex.org/W2218480779', 'https://openalex.org/W2293319370', 'https://openalex.org/W2310441748', 'https://openalex.org/W2335805754', 'https://openalex.org/W2338773685', 'https://openalex.org/W2395785890', 'https://openalex.org/W2398390426', 'https://openalex.org/W2409656339', 'https://openalex.org/W2463118776', 'https://openalex.org/W2480559039', 'https://openalex.org/W2763829062', 'https://openalex.org/W2782311151', 'https://openalex.org/W2794339025', 'https://openalex.org/W2800136432', 'https://openalex.org/W4234288885'], 'related_works': ['https://openalex.org/W4293204701', 'https://openalex.org/W2999094514', 'https://openalex.org/W2968050891', 'https://openalex.org/W2411405867', 'https://openalex.org/W2206647875', 'https://openalex.org/W2085700440', 'https://openalex.org/W2018405600', 'https://openalex.org/W1999628378', 'https://openalex.org/W1568452228', 'https://openalex.org/W1545079601'], 'abstract_inverted_index': {'Antibiotic-induced': [0], 'dysbiosis': [1], 'is': [2, 99], 'a': [3, 90], 'key': [4], 'factor': [5, 83], 'predisposing': [6], 'intestinal': [7, 20, 45, 49, 59, 74, 86, 109], 'infection': [8], 'by': [9, 57, 115], 'Clostridium': [10], 'difficile.': [11], 'Here,': [12], 'we': [13], 'show': [14], 'that': [15, 17, 106], 'interventions': [16], 'restore': [18], 'butyrate': [19, 102, 107], 'levels': [21], 'mitigate': [22], 'clinical': [23], 'and': [24, 47, 62, 97, 128], 'pathological': [25], 'features': [26], 'of': [27, 71, 73, 80, 122, 131], 'C.': [28, 36, 94, 116], 'difficile-induced': [29, 95], 'colitis.': [30], 'Butyrate': [31], 'has': [32], 'no': [33], 'effect': [34, 92], 'on': [35], 'difficile': [37, 117], 'colonization': [38], 'or': [39], 'toxin': [40], 'production.': [41], 'However,': [42], 'it': [43, 98], 'attenuates': [44], 'inflammation': [46], 'improves': [48], 'barrier': [50], 'function': [51], 'in': [52, 85, 93], 'infected': [53], 'mice,': [54], 'as': [55], 'shown': [56], 'reduced': [58], 'epithelial': [60, 75, 87, 110], 'permeability': [61], 'bacterial': [63], 'translocation,': [64], 'effects': [65], 'associated': [66], 'with': [67], 'the': [68, 81, 120, 132], 'increased': [69], 'expression': [70], 'components': [72], 'cell': [76], 'tight': [77], 'junctions.': [78], 'Activation': [79], 'transcription': [82], 'HIF-1': [84], 'cells': [88, 111], 'exerts': [89], 'protective': [91], 'colitis,': [96], 'required': [100], 'for': [101], 'effects.': [103], 'We': [104], 'conclude': [105], 'protects': [108], 'from': [112], 'damage': [113], 'caused': [114], 'toxins': [118], 'via': [119], 'stabilization': [121], 'HIF-1,': [123], 'mitigating': [124], 'local': [125], 'inflammatory': [126], 'response': [127], 'systemic': [129], 'consequences': [130], 'infection.': [133]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2940220885', 'counts_by_year': [{'year': 2024, 'cited_by_count': 49}, {'year': 2023, 'cited_by_count': 55}, {'year': 2022, 'cited_by_count': 52}, {'year': 2021, 'cited_by_count': 57}, {'year': 2020, 'cited_by_count': 38}, {'year': 2019, 'cited_by_count': 11}], 'updated_date': '2024-12-23T02:25:38.947750', 'created_date': '2019-04-25'}