Publication Information

{'id': 'https://openalex.org/W2923456802', 'doi': 'https://doi.org/10.7150/jca.29106', 'title': 'The Impact of Primary Tumor Sidedness on the Effect of Regorafenib in Refractory Metastatic Colorectal Cancer', 'display_name': 'The Impact of Primary Tumor Sidedness on the Effect of Regorafenib in Refractory Metastatic Colorectal Cancer', 'publication_year': 2019, 'publication_date': '2019-01-01', 'ids': {'openalex': 'https://openalex.org/W2923456802', 'doi': 'https://doi.org/10.7150/jca.29106', 'mag': '2923456802', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/31205516', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6548008'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.7150/jca.29106', 'pdf_url': 'https://www.jcancer.org/v10p1611.pdf', 'source': {'id': 'https://openalex.org/S200072998', 'display_name': 'Journal of Cancer', 'issn_l': '1837-9664', 'issn': ['1837-9664'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317973', 'host_organization_name': 'Ivyspring International Publisher', 'host_organization_lineage': ['https://openalex.org/P4310317973'], 'host_organization_lineage_names': ['Ivyspring International Publisher'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.jcancer.org/v10p1611.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5070300049', 'display_name': 'Sang Eun Yoon', 'orcid': 'https://orcid.org/0000-0002-0379-5297'}, 'institutions': [{'id': 'https://openalex.org/I2802194831', 'display_name': 'Samsung Medical Center', 'ror': 'https://ror.org/05a15z872', 'country_code': 'KR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802194831']}, {'id': 'https://openalex.org/I848706', 'display_name': 'Sungkyunkwan University', 'ror': 'https://ror.org/04q78tk20', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I848706']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Sang Eun Yoon', 'raw_affiliation_strings': ['Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea'], 'affiliations': [{'raw_affiliation_string': 'Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea', 'institution_ids': ['https://openalex.org/I2802194831', 'https://openalex.org/I848706']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100647502', 'display_name': 'Su Jin Lee', 'orcid': 'https://orcid.org/0000-0003-3405-9935'}, 'institutions': [{'id': 'https://openalex.org/I2802194831', 'display_name': 'Samsung Medical Center', 'ror': 'https://ror.org/05a15z872', 'country_code': 'KR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802194831']}, {'id': 'https://openalex.org/I848706', 'display_name': 'Sungkyunkwan University', 'ror': 'https://ror.org/04q78tk20', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I848706']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Su Jin Lee', 'raw_affiliation_strings': ['Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea'], 'affiliations': [{'raw_affiliation_string': 'Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea', 'institution_ids': ['https://openalex.org/I2802194831', 'https://openalex.org/I848706']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019406140', 'display_name': 'Jeeyun Lee', 'orcid': 'https://orcid.org/0000-0002-4911-6165'}, 'institutions': [{'id': 'https://openalex.org/I848706', 'display_name': 'Sungkyunkwan University', 'ror': 'https://ror.org/04q78tk20', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I848706']}, {'id': 'https://openalex.org/I2802194831', 'display_name': 'Samsung Medical Center', 'ror': 'https://ror.org/05a15z872', 'country_code': 'KR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802194831']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Jeeyun Lee', 'raw_affiliation_strings': ['Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea'], 'affiliations': [{'raw_affiliation_string': 'Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea', 'institution_ids': ['https://openalex.org/I848706', 'https://openalex.org/I2802194831']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057146015', 'display_name': 'Se Hoon Park', 'orcid': 'https://orcid.org/0000-0001-5084-9326'}, 'institutions': [{'id': 'https://openalex.org/I2802194831', 'display_name': 'Samsung Medical Center', 'ror': 'https://ror.org/05a15z872', 'country_code': 'KR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802194831']}, {'id': 'https://openalex.org/I848706', 'display_name': 'Sungkyunkwan University', 'ror': 'https://ror.org/04q78tk20', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I848706']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Se Hoon Park', 'raw_affiliation_strings': ['Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea'], 'affiliations': [{'raw_affiliation_string': 'Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea', 'institution_ids': ['https://openalex.org/I2802194831', 'https://openalex.org/I848706']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045587524', 'display_name': 'Joon Oh Park', 'orcid': 'https://orcid.org/0000-0001-6502-2612'}, 'institutions': [{'id': 'https://openalex.org/I2802194831', 'display_name': 'Samsung Medical Center', 'ror': 'https://ror.org/05a15z872', 'country_code': 'KR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802194831']}, {'id': 'https://openalex.org/I848706', 'display_name': 'Sungkyunkwan University', 'ror': 'https://ror.org/04q78tk20', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I848706']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Joon Oh Park', 'raw_affiliation_strings': ['Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea'], 'affiliations': [{'raw_affiliation_string': 'Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea', 'institution_ids': ['https://openalex.org/I2802194831', 'https://openalex.org/I848706']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015598872', 'display_name': 'Ho Yeong Lim', 'orcid': 'https://orcid.org/0000-0001-9325-2300'}, 'institutions': [{'id': 'https://openalex.org/I2802194831', 'display_name': 'Samsung Medical Center', 'ror': 'https://ror.org/05a15z872', 'country_code': 'KR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802194831']}, {'id': 'https://openalex.org/I848706', 'display_name': 'Sungkyunkwan University', 'ror': 'https://ror.org/04q78tk20', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I848706']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Ho Yeong Lim', 'raw_affiliation_strings': ['Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea'], 'affiliations': [{'raw_affiliation_string': 'Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea', 'institution_ids': ['https://openalex.org/I2802194831', 'https://openalex.org/I848706']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5065244228', 'display_name': 'Won Ki Kang', 'orcid': 'https://orcid.org/0000-0002-0049-8086'}, 'institutions': [{'id': 'https://openalex.org/I2802194831', 'display_name': 'Samsung Medical Center', 'ror': 'https://ror.org/05a15z872', 'country_code': 'KR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802194831']}, {'id': 'https://openalex.org/I848706', 'display_name': 'Sungkyunkwan University', 'ror': 'https://ror.org/04q78tk20', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I848706']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Won Ki Kang', 'raw_affiliation_strings': ['Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea'], 'affiliations': [{'raw_affiliation_string': 'Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea', 'institution_ids': ['https://openalex.org/I2802194831', 'https://openalex.org/I848706']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101437342', 'display_name': 'Young Suk Park', 'orcid': 'https://orcid.org/0000-0002-2900-0421'}, 'institutions': [{'id': 'https://openalex.org/I2802194831', 'display_name': 'Samsung Medical Center', 'ror': 'https://ror.org/05a15z872', 'country_code': 'KR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802194831']}, {'id': 'https://openalex.org/I848706', 'display_name': 'Sungkyunkwan University', 'ror': 'https://ror.org/04q78tk20', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I848706']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Young Suk Park', 'raw_affiliation_strings': ['Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea'], 'affiliations': [{'raw_affiliation_string': 'Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea', 'institution_ids': ['https://openalex.org/I2802194831', 'https://openalex.org/I848706']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5026351538', 'display_name': 'Seung Tae Kim', 'orcid': 'https://orcid.org/0000-0001-7335-1846'}, 'institutions': [{'id': 'https://openalex.org/I2802194831', 'display_name': 'Samsung Medical Center', 'ror': 'https://ror.org/05a15z872', 'country_code': 'KR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802194831']}, {'id': 'https://openalex.org/I848706', 'display_name': 'Sungkyunkwan University', 'ror': 'https://ror.org/04q78tk20', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I848706']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Seung Tae Kim', 'raw_affiliation_strings': ['Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea'], 'affiliations': [{'raw_affiliation_string': 'Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea', 'institution_ids': ['https://openalex.org/I2802194831', 'https://openalex.org/I848706']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2000, 'currency': 'AUD', 'value_usd': 1337, 'provenance': 'doaj'}, 'apc_paid': {'value': 2000, 'currency': 'AUD', 'value_usd': 1337, 'provenance': 'doaj'}, 'fwci': 0.937, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 14, 'citation_normalized_percentile': {'value': 0.99996, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 88, 'max': 89}, 'biblio': {'volume': '10', 'issue': '7', 'first_page': '1611', 'last_page': '1615'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11067', 'display_name': 'Colorectal Cancer Treatments and Studies', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11067', 'display_name': 'Colorectal Cancer Treatments and Studies', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11369', 'display_name': 'Genetic factors in colorectal cancer', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13110', 'display_name': 'Colorectal and Anal Carcinomas', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/regorafenib', 'display_name': 'Regorafenib', 'score': 0.97242403}, {'id': 'https://openalex.org/keywords/splenic-flexure', 'display_name': 'Splenic flexure', 'score': 0.6983258}, {'id': 'https://openalex.org/keywords/descending-colon', 'display_name': 'Descending colon', 'score': 0.66177726}, {'id': 'https://openalex.org/keywords/primary-tumor', 'display_name': 'Primary tumor', 'score': 0.58972627}, {'id': 'https://openalex.org/keywords/refractory', 'display_name': 'Refractory (planetary science)', 'score': 0.56305605}, {'id': 'https://openalex.org/keywords/transverse-colon', 'display_name': 'Transverse colon', 'score': 0.48687282}], 'concepts': [{'id': 'https://openalex.org/C2776248978', 'wikidata': 'https://www.wikidata.org/wiki/Q3891664', 'display_name': 'Regorafenib', 'level': 4, 'score': 0.97242403}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8923774}, {'id': 'https://openalex.org/C526805850', 'wikidata': 'https://www.wikidata.org/wiki/Q188874', 'display_name': 'Colorectal cancer', 'level': 3, 'score': 0.82480013}, {'id': 'https://openalex.org/C3019760618', 'wikidata': 'https://www.wikidata.org/wiki/Q5144815', 'display_name': 'Splenic flexure', 'level': 5, 'score': 0.6983258}, {'id': 'https://openalex.org/C2781187634', 'wikidata': 'https://www.wikidata.org/wiki/Q20969980', 'display_name': 'KRAS', 'level': 4, 'score': 0.66749614}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.66216546}, {'id': 'https://openalex.org/C2778292851', 'wikidata': 'https://www.wikidata.org/wiki/Q2562565', 'display_name': 'Descending colon', 'level': 3, 'score': 0.66177726}, {'id': 'https://openalex.org/C2780283643', 'wikidata': 'https://www.wikidata.org/wiki/Q2110267', 'display_name': 'Primary tumor', 'level': 4, 'score': 0.58972627}, {'id': 'https://openalex.org/C142424586', 'wikidata': 'https://www.wikidata.org/wiki/Q7307572', 'display_name': 'Refractory (planetary science)', 'level': 2, 'score': 0.56305605}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.5157604}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.49784994}, {'id': 'https://openalex.org/C2777807078', 'wikidata': 'https://www.wikidata.org/wiki/Q2619732', 'display_name': 'Transverse colon', 'level': 2, 'score': 0.48687282}, {'id': 'https://openalex.org/C2778822529', 'wikidata': 'https://www.wikidata.org/wiki/Q1951525', 'display_name': 'Progressive disease', 'level': 3, 'score': 0.45114398}, {'id': 'https://openalex.org/C2781074409', 'wikidata': 'https://www.wikidata.org/wiki/Q158716', 'display_name': 'Rectum', 'level': 2, 'score': 0.45040542}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.35739142}, {'id': 'https://openalex.org/C2778435480', 'wikidata': 'https://www.wikidata.org/wiki/Q840387', 'display_name': 'Colonoscopy', 'level': 4, 'score': 0.291736}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.24374664}, {'id': 'https://openalex.org/C2779013556', 'wikidata': 'https://www.wikidata.org/wiki/Q181876', 'display_name': 'Metastasis', 'level': 3, 'score': 0.20086244}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C87355193', 'wikidata': 'https://www.wikidata.org/wiki/Q411', 'display_name': 'Astrobiology', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.7150/jca.29106', 'pdf_url': 'https://www.jcancer.org/v10p1611.pdf', 'source': {'id': 'https://openalex.org/S200072998', 'display_name': 'Journal of Cancer', 'issn_l': '1837-9664', 'issn': ['1837-9664'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317973', 'host_organization_name': 'Ivyspring International Publisher', 'host_organization_lineage': ['https://openalex.org/P4310317973'], 'host_organization_lineage_names': ['Ivyspring International Publisher'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc6548008', 'pdf_url': 'https://europepmc.org/articles/pmc6548008?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548008', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/31205516', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.7150/jca.29106', 'pdf_url': 'https://www.jcancer.org/v10p1611.pdf', 'source': {'id': 'https://openalex.org/S200072998', 'display_name': 'Journal of Cancer', 'issn_l': '1837-9664', 'issn': ['1837-9664'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317973', 'host_organization_name': 'Ivyspring International Publisher', 'host_organization_lineage': ['https://openalex.org/P4310317973'], 'host_organization_lineage_names': ['Ivyspring International Publisher'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.82, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 23, 'referenced_works': ['https://openalex.org/W14234604', 'https://openalex.org/W1799482054', 'https://openalex.org/W1934094702', 'https://openalex.org/W1968209756', 'https://openalex.org/W2000435171', 'https://openalex.org/W2012708129', 'https://openalex.org/W2019607817', 'https://openalex.org/W2039112796', 'https://openalex.org/W2051550002', 'https://openalex.org/W2074607266', 'https://openalex.org/W2111851685', 'https://openalex.org/W2113029107', 'https://openalex.org/W2139505515', 'https://openalex.org/W2147834058', 'https://openalex.org/W2158240350', 'https://openalex.org/W2406315769', 'https://openalex.org/W2413676985', 'https://openalex.org/W2531319683', 'https://openalex.org/W2558788971', 'https://openalex.org/W2599059217', 'https://openalex.org/W2768567726', 'https://openalex.org/W2907720222', 'https://openalex.org/W2917837889'], 'related_works': ['https://openalex.org/W4387734155', 'https://openalex.org/W4309179265', 'https://openalex.org/W4254851444', 'https://openalex.org/W4230741033', 'https://openalex.org/W4214676303', 'https://openalex.org/W4205380886', 'https://openalex.org/W3180706886', 'https://openalex.org/W2986505932', 'https://openalex.org/W2333774038', 'https://openalex.org/W2074298652'], 'abstract_inverted_index': {'Recently,': [0], 'the': [1, 4, 22, 32, 35, 71, 83, 95, 106, 171, 174, 192, 230, 255, 258, 265, 306], 'sidedness': [2, 33, 256], 'of': [3, 24, 34, 82, 105, 148, 160, 173, 257, 267], 'primary': [5, 36, 175, 259], 'tumor': [6, 37, 176, 260], '(right': [7], 'versus': [8], 'left)': [9], 'has': [10], 'been': [11], 'investigated': [12], 'for': [13, 292], 'its': [14], 'ability': [15], 'to': [16, 170, 202, 210, 240, 248], 'prognosticate': [17], 'and': [18, 31, 65, 125, 194, 232, 264, 282], 'predict': [19], 'outcomes.We': [20], 'evaluated': [21], 'effect': [23, 276], 'regorafenib': [25, 57, 188, 224, 301], 'based': [26, 304], 'on': [27, 277, 305], 'KRAS': [28], 'mutation': [29], 'status': [30], 'in': [38, 70, 94, 165, 182], 'patients': [39, 47, 132, 150], 'with': [40, 48, 56, 187, 218, 223], 'metastatic': [41, 50, 268], 'colorectal': [42, 51], 'cancer': [43, 52, 124], '(mCRC).We': [44], 'analyzed': [45], '135': [46, 116], 'refractory': [49], '(mCRC)': [53], 'being': [54], 'treated': [55], 'at': [58], 'Samsung': [59], 'Medical': [60], 'Center,': [61], 'between': [62, 191, 229], 'January': [63, 66], '2014': [64], '2018.Primary': [67], 'tumors': [68, 92], 'originating': [69, 93], 'splenic': [72], 'flexure,': [73, 101], 'descending': [74], 'colon,': [75, 77, 99], 'sigmoid': [76], 'rectum,': [78], 'or': [79, 102, 167], 'proximal': [80], 'third': [81], 'transverse': [84, 107], 'colon': [85, 108, 123, 130], 'were': [86, 109], 'defined': [87, 110], 'as': [88, 111], 'left-sided': [89], 'CRC': [90, 113], '(LC).Primary': [91], 'appendix,': [96], 'cecum,': [97], 'ascending': [98], 'hepatic': [100], 'distal': [103], 'two-thirds': [104], 'right-sided': [112, 129], '(RC).Among': [114], 'all': [115], 'patients,': [117], '100': [118], '(74.1%)': [119], 'had': [120, 128, 151, 273], 'left': [121], 'sided': [122], '35': [126], '(25.9%)': [127], 'cancer.No': [131], 'achieved': [133, 139], 'a': [134, 140, 144, 155, 216, 274, 288], 'complete': [135], 'response,': [136, 142], 'but': [137, 294], 'four': [138], 'partial': [141], 'revealing': [143], 'response': [145], 'rate': [146, 158], '(RR)': [147], '3.0%.Thirty-seven': [149], 'stable': [152], 'disease,': [153], 'yielding': [154], 'disease': [156], 'control': [157], '(DCR)': [159], '30.4%.There': [161], 'was': [162, 189, 225], 'no': [163], 'difference': [164, 181], 'RR': [166], 'DCR': [168], 'according': [169], 'location': [172], '(LC': [177, 261], 'vs.': [178, 204, 242, 262, 271], 'RC).A': [179], 'significant': [180], 'progression': [183], 'free': [184], 'survival': [185], '(PFS)': [186], 'observed': [190], 'LC': [193, 231], 'RC': [195, 233], 'groups': [196, 234], '(2.6': [197], 'months;': [198, 206, 236, 244], '95%': [199, 207, 237, 245], 'CI,': [200, 208, 238, 246], '2.0': [201], '3.1': [203], '1.9': [205], '1.6': [209], '2.3;': [211], 'P': [212, 250, 283], '=': [213, 251, 280, 284], '0.04,': [214], 'respectively).In': [215], 'subpopulation': [217], 'wild': [219], 'type': [220], 'KRAS,': [221], 'PFS': [222, 278], 'also': [226], 'significantly': [227], 'different': [228], '(2.9': [235], '1.5': [239], '4.3': [241], '2.1': [243], '0.6': [247], '3.6;': [249], '0.04).On': [252], 'multivariate': [253], 'analysis,': [254], 'RC)': [263], 'number': [266], 'sites': [269], '(≤1': [270], '2>)': [272], 'prognostic': [275], '(P': [279], '0.01': [281], '0.01,': [285], 'respectively).Regorafenib': [286], 'is': [287, 302], 'current': [289], 'standard': [290], 'treatment': [291, 295], 'CRC,': [293], 'outcomes': [296], 'may': [297], 'be': [298], 'improved': [299], 'if': [300], 'administered': [303], 'appropriate': [307], 'biomarker.': [308]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2923456802', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}], 'updated_date': '2024-12-11T08:07:19.052090', 'created_date': '2019-04-01'}