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'https://openalex.org/W77040905', 'https://openalex.org/W967062177'], 'related_works': ['https://openalex.org/W4391375266', 'https://openalex.org/W4389568370', 'https://openalex.org/W3108674512', 'https://openalex.org/W3032375762', 'https://openalex.org/W3031052312', 'https://openalex.org/W2899084033', 'https://openalex.org/W2748952813', 'https://openalex.org/W2080531066', 'https://openalex.org/W1995515455', 'https://openalex.org/W1506200166'], 'abstract_inverted_index': {'Protein': [0, 135], 'supplementation': [1, 136, 721], 'therapy': [2, 137, 513, 1080, 1115], 'using': [3, 138], 'in': [4, 74, 76, 113, 127, 139, 209, 211, 248, 262, 274, 311, 374, 379, 428, 533, 537, 556, 559, 598, 614, 636, 695, 748, 751, 834, 989, 1030, 1072, 1488, 1511, 1546, 1569, 1583, 1603, 1653, 1669, 1691, 1712, 1749, 1774, 1802, 1844, 1881, 1907, 1956, 2104, 2122, 2236, 2277, 2295, 2301, 2390, 2397, 2436, 2453, 2551, 2750, 2755, 2763, 2798, 2812, 2847, 2875, 2880, 2918, 2949, 2958, 2989, 3027, 3060, 3137, 3143, 3289, 3447, 3608, 3647, 3766, 3803, 3806, 3850, 3916, 4145, 4155, 4161, 4170, 4187, 4213, 4229, 4250], 'vitro-transcribed': [5, 140, 534], '(IVT)': [6, 141, 535], 'mRNA': [7, 26, 39, 65, 81, 89, 128, 142, 161, 174, 200, 216, 224, 263, 507, 536, 544, 613, 653, 693, 715, 734, 743, 812, 829, 927, 945, 1053, 1149], 'for': [8, 143, 286, 340, 346, 360, 514, 719, 753, 932, 1000, 1057, 1186, 1223, 1243, 1253, 1503, 2033, 2150, 2163, 2181, 2406, 2605, 2624, 2680, 3273, 3285, 3327, 3575, 3694, 4031], 'genetic': [9, 94, 144, 229, 1507], 'diseases': [10, 109, 145, 244, 515, 1140], 'contains': [11, 146], 'huge': [12, 147], 'potential': [13, 148, 840], 'as': [14, 40, 52, 149, 175, 187, 966, 1054, 1088, 1098, 1100, 1104, 1851, 1959, 2404, 2410, 2537, 3191, 3449], 'a': [15, 28, 41, 53, 100, 122, 150, 163, 176, 188, 235, 257, 271, 349, 376, 436, 511, 526, 550, 609, 615, 716, 754, 815, 891, 1031, 1055, 1145, 1172, 1221, 1441, 1543, 1716, 2041, 2387, 2552, 2837, 2877, 2919, 3140, 3144, 3192, 3450, 3851, 4039, 4168], 'new': [16, 151, 512], 'class': [17, 152], 'of': [18, 24, 31, 37, 64, 80, 103, 125, 153, 159, 166, 172, 199, 215, 238, 260, 294, 399, 424, 431, 532, 612, 618, 633, 641, 652, 681, 692, 711, 736, 741, 783, 794, 811, 828, 893, 943, 957, 969, 976, 992, 1034, 1081, 1135, 1148, 1155, 1180, 1211, 1217, 1267, 1294, 1339, 1387, 1391, 1404, 1425, 1578, 1636, 1771, 1854, 1860, 1867, 1877, 2011, 2043, 2085, 2093, 2175, 2184, 2201, 2210, 2224, 2462, 2489, 2511, 2532, 2542, 2554, 2581, 2585, 2670, 2683, 2707, 2730, 2736, 2777, 2794, 2845, 2888, 2922, 2951, 3035, 3103, 3146, 3194, 3237, 3275, 3408, 3440, 3452, 3493, 3533, 3578, 3814, 3858, 3877, 3911, 3919, 3952, 3995, 4041, 4142, 4173, 4184, 4217, 4245, 4253], 'therapy.': [19, 117, 154, 252], 'From': [20, 155], 'the': [21, 34, 75, 87, 156, 169, 210, 222, 275, 295, 425, 523, 538, 670, 676, 708, 712, 954, 958, 981, 990, 995, 1193, 1202, 1208, 1218, 1227, 1235, 1249, 1273, 1278, 1281, 1284, 1317, 1340, 1344, 1504, 1713, 1754, 1807, 1861, 1875, 1908, 1948, 2001, 2172, 2182, 2204, 2208, 2211, 2215, 2222, 2297, 2302, 2398, 2437, 2619, 2675, 2681, 2746, 2841, 3147, 3280, 3494, 3917, 4171, 4214, 4218, 4251], 'early': [22, 157], 'ages': [23, 158], 'synthetic': [25, 160], 'discovery,': [27, 162], 'great': [29, 164], 'number': [30, 165, 2842], 'studies': [32, 167, 2396, 2466], 'showed': [33, 168, 541], 'versatile': [35, 170], 'use': [36, 171, 2368], 'IVT': [38, 173], 'novel': [42, 177, 377, 2586], 'approach': [43, 178], 'to': [44, 60, 91, 179, 195, 226, 348, 510, 657, 675, 831, 836, 971, 978, 997, 1121, 1161, 1176, 1201, 1421, 1756, 1809, 1858, 1871, 1901, 1946, 2000, 2102, 2234, 2245, 2290, 2333, 2372, 2469, 2663, 2835, 3540, 3998, 4226], 'supplement': [45, 180], 'faulty': [46, 181], 'or': [47, 182, 446, 1157, 1298, 1306, 1865, 2734, 3931, 4113], 'absent': [48, 183], 'protein': [49, 115, 184, 250, 519, 524, 720, 756, 1078, 1094, 3323, 3651], 'and': [50, 69, 110, 130, 185, 204, 245, 265, 277, 280, 353, 355, 381, 439, 479, 558, 679, 750, 790, 948, 974, 1092, 1110, 1119, 1139, 1159, 1182, 1199, 1215, 1241, 1245, 1248, 1257, 1264, 1269, 1291, 1316, 1396, 1412, 1456, 1462, 1472, 1486, 1508, 1551, 1564, 1572, 1710, 1718, 1780, 1826, 1846, 1874, 1888, 1910, 1916, 1918, 1924, 1934, 1936, 1969, 1980, 1984, 1996, 2039, 2074, 2087, 2095, 2107, 2125, 2178, 2193, 2199, 2207, 2226, 2251, 2259, 2284, 2342, 2375, 2409, 2458, 2482, 2514, 2603, 2608, 2626, 2633, 2694, 2757, 2761, 2775, 2843, 2962, 2992, 3033, 3186, 3279, 3284, 3291, 3331, 3370, 3530, 3654, 3698, 3770, 3823, 3886, 3888, 3895, 3898, 3909, 3956, 3969, 4037, 4073, 4099, 4164, 4182, 4232, 4243], 'also': [51, 120, 186, 255, 1167, 1953, 4208], 'vaccine.': [54, 189], 'Many': [55, 190], 'modifications': [56, 129, 191, 264, 968], 'have': [57, 192, 830, 2400, 2836], 'been': [58, 193, 2792, 2833], 'made': [59, 194], 'produce': [61, 196, 1913, 1978], 'high': [62, 197, 755, 3875], 'expressions': [63, 198], 'causing': [66, 201], 'less': [67, 202], 'immunogenicity': [68, 203, 841, 973], 'more': [70, 205], 'stability.': [71, 206], 'Recent': [72, 207, 2395], 'advancements': [73, 112, 208, 247, 988], 'vivo': [77, 212, 2876], 'lung': [78, 95, 108, 213, 230, 243, 1028, 1082, 1117, 1124, 1136, 1163, 1170, 1219, 1512, 1547, 1579, 1714, 1855, 4102], 'delivery': [79, 214], 'complexed': [82, 217], 'with': [83, 106, 218, 241, 498, 517, 525, 745, 1142, 1205, 1418, 1470, 1605, 1829, 2046, 2826, 3064, 3101, 3139, 3367, 3660, 3733, 3772, 3811, 3855, 4044], 'various': [84, 93, 107, 219, 228, 242, 1584, 1928], 'carriers': [85, 220], 'encouraged': [86, 221], 'whole': [88, 223], 'community': [90, 225], 'tackle': [92, 227], 'diseases.': [96, 231], 'This': [97, 118, 232, 253, 604, 705, 1229, 1998, 2738], 'review': [98, 119, 233, 254, 1075, 1131], 'gives': [99, 234, 508, 1132], 'comprehensive': [101, 236, 1146], 'overview': [102, 237, 1134], 'cells': [104, 239, 279, 430, 1271, 1409, 1424, 1563, 1926, 1941, 1977, 1991, 2169, 2287, 2327, 2367, 2435, 2501, 2650, 2661, 2673, 3868, 3872, 3913, 3958, 3961, 4186, 4204, 4207, 4247], 'associated': [105, 240, 516, 1141, 2045, 4043], 'recent': [111, 246, 987], 'mRNA-based': [114, 249], 'replacement': [116, 251, 1079], 'covers': [121, 256], 'brief': [123, 258], 'summary': [124, 259, 1147], 'developments': [126, 261], 'nanocarriers': [131, 266, 977, 993, 1160], 'toward': [132, 267], 'clinical': [133, 268, 1902], 'translation.': [134, 269], 'RNA,': [270], 'fundamental': [272], 'molecule': [273, 718], 'eukaryotic': [276], 'prokaryotic': [278], 'viruses,': [281], 'came': [282], 'recently': [283, 3824], 'into': [284, 549, 595, 3935], 'focus': [285], 'therapeutic': [287, 610, 623, 838], 'approaches:1Robertson': [288], 'M.P.': [289], 'Joyce': [290], 'G.F.': [291, 625], 'The': [292, 308, 327, 529, 856, 986, 1169, 1287, 1385, 1399, 1435, 1452, 2161, 2186, 2487, 3907, 4241], 'origins': [293], 'RNA': [296, 309, 329, 344, 400, 501, 568, 785, 857, 894], 'world.Cold': [297], 'Spring': [298, 313, 2636], 'Harb.': [299, 314, 2637], 'Perspect.': [300, 315, 2638], 'Biol.': [301, 316, 936, 2558, 2639, 2931, 4108], '2012;': [302, 317, 2822, 3201, 3244, 3413, 3619, 3972], '4:': [303, 318], 'a003608Google': [304], 'Scholar,': [305, 320, 391, 409, 453, 491, 577, 765, 800, 867, 904, 916, 1041, 1351, 1497, 1518, 1611, 1660, 1699, 1764, 1817, 2054, 2131, 2563, 2595, 2643, 3975, 4052, 4080], '2Cech': [306], 'T.R.': [307, 2015, 2064, 2352, 4013], 'worlds': [310], 'context.Cold': [312], 'a006742Google': [319], '3Neveu': [321], 'M.': [322, 415, 723, 775, 924, 1357, 1524, 1532, 1534, 1538, 1625, 1627, 1666, 1688, 1730, 1783, 1819, 2310, 2320, 2346, 2975, 3044, 3091, 3208, 3256, 3359, 3397, 3476, 3521, 3588, 3603, 3685, 3721, 3747, 3759, 3827, 3835, 3902, 4084, 4124, 4236], 'Kim': [323], 'H.J.': [324], 'Benner': [325], 'S.A.': [326, 4056], '"strong"': [328], 'world': [330], 'hypothesis:': [331], 'fifty': [332], 'years': [333], 'old.Astrobiology.': [334], '2013;': [335, 3110, 3374, 3459, 3702, 3738, 3777], '13:': [336, 3926], '391-403Google': [337], 'Scholar': [338, 506, 603, 649, 704, 825, 941, 1066, 1384, 1451, 1556, 1642, 1679, 1728, 1779, 1839, 1975, 2083, 2160, 2268, 2341, 2385, 2448, 2499, 2616, 2659, 2693, 2716, 2786, 2825, 2873, 2935, 3004, 3042, 3113, 3161, 3204, 3247, 3297, 3339, 3377, 3416, 3462, 3550, 3584, 3669, 3705, 3741, 3780, 3822, 3866, 3928, 4008, 4112, 4153, 4202], 'tRNAs': [339], 'nonsense': [341, 382, 3141], 'mutation': [342, 3142, 3190, 3362, 3728], 'correction,': [343], 'aptamers': [345], 'binding': [347], 'specific': [350, 404, 1123], 'target': [351, 1001, 1162], 'molecule,': [352], 'RNAi': [354], 'long': [356], 'noncoding': [357], 'RNAs': [358], '(lncRNAs)': [359], 'gene': [361, 427, 593, 2241, 2985], 'regulation.4Murgola': [362], 'E.J.': [363], 'Prather': [364], 'N.E.': [365], 'Mims': [366], 'B.H.': [367], 'Pagel': [368], 'F.T.': [369], 'Hijazi': [370], 'K.A.': [371, 3636], 'Anticodon': [372], 'shift': [373], 'tRNA:': [375], 'mechanism': [378, 4216], 'missense': [380], 'suppression.Proc.': [383], 'Natl.': [384, 570, 2378, 2441, 2686, 3154], 'Acad.': [385, 571, 2379, 2442, 2687, 3155], 'Sci.': [386, 572, 2380, 2443, 2688, 3156], 'USA.': [387, 573, 2381, 2444, 2689, 3157], '1983;': [388], '80:': [389], '4936-4939Google': [390], '5Ellington': [392], 'A.D.': [393], 'Szostak': [394], 'J.W.': [395], 'In': [396, 1891, 2220, 2787, 4002], 'vitro': [397, 557], 'selection': [398], 'molecules': [401], 'that': [402, 542, 952, 1892, 1982, 2170, 2545, 2617, 3873], 'bind': [403], 'ligands.Nature.': [405], '1990;': [406, 600], '346:': [407], '818-822Google': [408], '6Cogoni': [410], 'C.': [411, 725, 731, 777, 1045, 1629, 1664, 1686, 2116, 2423, 2903, 2967, 3210, 3393, 3519, 3570, 3598, 3644, 3689, 3843, 4090, 4131], 'Irelan': [412], 'J.T.': [413], 'Schumacher': [414], 'Schmidhauser': [416], 'T.J.': [417], 'Selker': [418], 'E.U.': [419], 'Macino': [420], 'G.': [421, 587, 1331, 1648, 2013, 2058, 2413, 2805, 2851, 2979, 3016, 3260, 3566, 3983, 4011], 'Transgene': [422], 'silencing': [423], 'al-1': [426], 'vegetative': [429], 'Neurospora': [432], 'is': [433, 928, 1166, 1220, 1542, 2031, 2228, 2546, 2810, 2944, 3271, 3325, 3573, 3692, 3764, 4029], 'mediated': [434, 842], 'by': [435, 521, 608, 843, 946, 1152, 1460, 2154, 2167, 2191, 2217, 2504, 2723, 2885, 2946, 3405, 3491, 3967], 'cytoplasmic': [437, 3576], 'effector': [438], 'does': [440], 'not': [441, 1943, 2549], 'depend': [442], 'on': [443, 500, 1068, 1077, 1277, 2840], 'DNA-DNA': [444], 'interactions': [445], 'DNA': [447], 'methylation.EMBO': [448], 'J.': [449, 851, 922, 1009, 1329, 1371, 1430, 1615, 1621, 1722, 1962, 2019, 2491, 2867, 2927, 2998, 3069, 3107, 3198, 3216, 3241, 3262, 3309, 3311, 3456, 3501, 3544, 3592, 3663, 3774, 3782, 3829, 3841, 3904, 3950, 3989, 3993, 4017, 4066, 4104, 4192, 4238], '1996;': [450, 1553], '15:': [451, 1495, 2266], '3153-3163Google': [452], '7Chen': [454], 'X.': [455, 2905, 3083], 'He': [456], 'L.': [457, 471, 473, 1047, 1684, 2318, 3424, 3627, 3794, 3831, 3942, 3981], 'Zhao': [458], 'Y.': [459, 461, 2017, 2023, 2060, 2698, 3085, 3387, 4015, 4021], 'Li': [460, 3084], 'Zhang': [462, 3563], 'S.': [463, 767, 769, 804, 908, 1367, 1536, 1742, 1795, 1821, 2114, 2907, 3020, 3133, 3225, 4118], 'Sun': [464], 'K.': [465, 467, 493, 918, 1522, 1738, 1791, 2112, 2425, 2524, 2567, 3008, 3317, 3515], 'So': [466], 'Chen': [468, 1366, 2057, 3785, 3949, 3984, 3992], 'F.': [469, 1365, 2304, 3266], 'Zhou': [470, 4059], 'Lu': [472], 'et': [474, 889, 1022, 1372, 1539, 2323, 2432, 3025, 3094, 3183, 3226, 3269, 3318, 3360, 3398, 3437, 3483, 3528, 3571, 3606, 3645, 3690, 3726, 3762, 3801, 3846], 'al.Malat1': [475], 'regulates': [476, 2040, 4038], 'myogenic': [477], 'differentiation': [478, 2038, 2073, 4036], 'muscle': [480, 597, 1239, 1484], 'regeneration': [481, 1571], 'through': [482, 1192], 'modulating': [483], 'MyoD': [484], 'transcriptional': [485], 'activity.Cell': [486], 'Discov.': [487], '2017;': [488, 1676, 1696, 2640, 4005], '3:': [489], '17002Google': [490], '8Lundstrom': [492], 'Special': [494], 'Issue:': [495], 'Gene': [496], 'Therapy': [497], 'Emphasis': [499], 'Interference.Viruses.': [502], '2015;': [503, 1639, 2080, 2656, 4150], '7:': [504, 3973, 4006], '4482-4487Google': [505], 'rise': [509], 'functional': [518, 551, 664], 'loss': [520, 1876, 2887], 'supplementing': [522], 'transcript': [527, 1150], 'encoding.': [528], 'first': [530, 1505], 'study': [531], 'late': [539], '1980s': [540], 'this': [543, 1074, 1130], 'can': [545, 686, 2720, 2740], 'be': [546, 688, 832, 2451, 2721], 'directly': [547, 1899], 'translated': [548], 'form': [552], 'immediately': [553], 'after': [554], 'transfection': [555, 735, 810], 'vivo.9Malone': [560], 'R.W.': [561, 581, 2139], 'Felgner': [562, 590], 'P.L.': [563, 591], 'Verma': [564], 'I.M.': [565], 'Cationic': [566], 'liposome-mediated': [567], 'transfection.Proc.': [569], '1989;': [574, 1494], '86:': [575], '6077-6081Google': [576], '10Wolff': [578], 'J.A.': [579, 855, 1644, 1966, 2029, 2062, 2066, 2255, 2645, 2899, 4027], 'Malone': [580], 'Williams': [582], 'P.': [583, 733, 773, 806, 869, 875, 1013, 1526, 1528, 1734, 1787, 2056, 2141, 2316, 2417, 2973, 2981, 3052, 3054, 3117, 3638, 3790], 'Chong': [584], 'W.': [585, 3430, 3900, 4234], 'Acsadi': [586], 'Jani': [588], 'A.': [589, 771, 888, 1005, 1474, 1598, 1619, 1740, 1746, 1793, 1799, 2025, 2145, 2350, 2429, 2575, 2767, 2801, 2803, 3010, 3012, 3014, 3046, 3077, 3163, 3212, 3220, 3254, 3268, 3299, 3305, 3341, 3351, 3381, 3466, 3513, 3517, 3523, 3594, 3671, 3707, 3906, 4023, 4122, 4127, 4240], 'Direct': [592], 'transfer': [594, 1179], 'mouse': [596, 1032, 2034, 2920, 4032], 'vivo.Science.': [599], '247:': [601], '1465-1468Google': [602], 'was': [605, 2893], 'shortly': [606], 'followed': [607, 2884], 'application': [611], 'temporary': [616], 'reversal': [617], 'diabetes': [619, 634], 'insipidus,': [620], 'unraveling': [621], 'its': [622, 658, 949], 'potential.11Jirikowski': [624], 'Sanna': [626], 'P.P.': [627], 'Maciejewski-Lenoir': [628], 'D.': [629, 926, 1613, 2137, 3123, 3347, 3554, 3687, 3711, 3938, 3977], 'Bloom': [630], 'F.E.': [631], 'Reversal': [632], 'insipidus': [635], 'Brattleboro': [637], 'rats:': [638], 'intrahypothalamic': [639], 'injection': [640], 'vasopressin': [642], 'mRNA.Science.': [643], '1992;': [644], '255:': [645], '996-998Scopus': [646], '(138)': [647], 'Google': [648, 703, 1450, 2340, 2594, 4201], 'Therapeutic': [650], 'applications': [651], 'are': [654, 984, 1127, 1458, 1581, 1842, 1920, 1942, 2091, 2165, 2179, 2188, 2275, 2288, 2467, 2502, 2711, 3869, 4158, 4224], 'advantageous': [655], 'due': [656, 674, 1857, 1870, 2233, 3539], 'unique': [659, 1174], 'properties.': [660], 'Cytoplasm': [661], 'being': [662, 4205], "mRNA's": [663], 'site': [665, 1210], 'requires': [666, 1231, 2393], 'no': [667], 'transportation': [668], 'across': [669], 'nuclear': [671], 'membrane.': [672, 960], 'Furthermore,': [673, 1144], 'transient': [677], 'nature': [678, 1845], 'biodegradability': [680], 'mRNA,': [682], 'permanent': [683, 709], 'adverse': [684], 'effects': [685], 'potentially': [687], 'avoided.12Newbury': [689], 'S.F.': [690], 'Control': [691], 'stability': [694], 'eukaryotes.Biochem.': [696], 'Soc.': [697, 2264, 2612], 'Trans.': [698], '2006;': [699, 762, 797], '34:': [700], '30-34Scopus': [701], '(0)': [702], 'includes': [706, 1378], 'preventing': [707, 2151], 'manipulation': [710], 'genome,': [713], 'making': [714], 'prevalent': [717], 'therapy.13Mockey': [722], 'Gonçalves': [724], 'Dupuy': [726], 'F.P.': [727], 'Lemoine': [728], 'F.M.': [729], 'Pichon': [730], 'Midoux': [732], 'dendritic': [737, 795, 1990], 'cells:': [738], 'synergistic': [739], 'effect': [740, 2839], 'ARCA': [742], 'capping': [744, 1158], 'Poly(A)': [746], 'chains': [747], 'cis': [749], 'trans': [752], 'expression': [757], 'level.Biochem.': [758], 'Biophys.': [759, 819], 'Res.': [760, 820, 863, 900, 1493, 1675, 1695], 'Commun.': [761, 821, 3862], '340:': [763], '1062-1068Google': [764], '14Holtkamp': [766], 'Kreiter': [768], 'Selmi': [770], 'Simon': [772], 'Koslowski': [774], 'Huber': [776], 'Türeci': [778], 'O.': [779, 1732, 1744, 1785, 1797], 'Sahin': [780], 'U.': [781], 'Modification': [782, 858], 'antigen-encoding': [784], 'increases': [786], 'stability,': [787], 'translational': [788], 'efficacy,': [789], 'T-cell': [791], 'stimulatory': [792], 'capacity': [793], 'cells.Blood.': [796], '108:': [798, 2446], '4009-4017Google': [799], '15Elango': [801], 'N.': [802, 1015, 1019, 1590, 3024, 3264, 3303, 3391], 'Elango': [803], 'Shivshankar': [805], 'Katz': [807], 'M.S.': [808], 'Optimized': [809], 'transcribed': [813], 'from': [814, 1753, 1806, 1922, 2674, 2815, 2941, 3959], 'd(A/T)100': [816], 'tail-containing': [817], 'vector.Biochem.': [818], '2005;': [822, 913], '330:': [823], '958-966Google': [824], 'Several': [826], 'aspects': [827], 'addressed': [833], 'order': [835], 'achieve': [837, 1113], 'benefits:': [839], 'innate': [844, 1937, 1949, 1986, 1993, 2298, 2653, 3889], 'immune': [845, 1565, 1938, 1950, 1987, 2008, 2299, 2407, 3890], 'system': [846, 1951, 2300], 'reactions': [847], '(pattern': [848], 'recognition': [849], 'receptor),16Rozenski': [850], 'Crain': [852], 'P.F.': [853], 'McCloskey': [854], 'Database:': [859], '1999': [860], 'update.Nucleic': [861, 898], 'Acids': [862, 899], '1999;': [864, 1657, 4197], '27:': [865], '196-197Google': [866], '17Boccaletto': [868], 'Machnicka': [870], 'M.A.': [871, 3081, 3167, 3525, 3743], 'Purta': [872], 'E.': [873, 1021, 1617, 2306, 2849, 3119, 3127, 3395, 3568], 'Piatkowski': [874], 'Baginski': [876], 'B.': [877, 1043, 1361, 2322, 3115, 3683, 3717, 4129], 'Wirecki': [878], 'T.K.': [879], 'de': [880, 3632], 'Crécy-Lagard': [881], 'V.': [882, 1327, 1359, 1428, 2110, 2314, 2977], 'Ross': [883], 'R.': [884, 1323, 1325, 1476, 3018, 3075, 3079, 3087, 3464, 3629, 3677, 3755], 'Limbach': [885], 'P.A.': [886], 'Kotter': [887], 'al.MODOMICS:': [890], 'database': [892], 'modification': [895, 1154], 'pathways.': [896], '2017': [897], '2018;': [901, 1038, 1063, 1348, 1381, 1972, 2128, 2265], '46:': [902, 3820], 'D303-D307Google': [903], '18Ishii': [905], 'K.J.': [906], 'Akira': [907], 'TLR': [909], 'ignores': [910], 'methylated': [911], 'RNA?.Immunity.': [912], '23:': [914, 1762, 1815, 2871], '111-113Google': [915], '19Karikó': [917], 'Ni': [919], 'H.': [920, 1017, 1520, 1530, 1662, 2027, 2431, 3006, 3022, 3093, 3206, 3315, 3511, 3552, 3556, 3562, 3600, 3605, 3798, 3837, 3946, 3987, 4025], 'Capodici': [921], 'Lamphier': [923], 'Weissman': [925], 'an': [929, 1133, 1719, 2292, 2538, 2742, 4210], 'endogenous': [930], 'ligand': [931], 'Toll-like': [933], 'receptor': [934], '3.J.': [935], 'Chem.': [937, 2559], '2004;': [938], '279:': [939], '12542-12550Google': [940], 'degradation': [942], 'single-stranded': [944], 'nucleases,': [947], 'negative': [950], 'charge': [951], 'inhibits': [953, 4074], 'passive': [955], 'crossing': [956, 980], 'cell': [959, 982, 1125, 1137, 1164, 1559, 1895, 2005, 2037, 2072, 2089, 2732, 2752, 2925, 4035], 'Concerning': [961], 'these': [962, 3933, 4157], 'obstacles,': [963], 'solutions': [964], 'such': [965, 1087, 1103, 1850], 'chemical': [967, 1153], 'nucleosides': [970, 1156], 'reduce': [972], 'usage': [975], 'facilitate': [979], 'membrane': [983], 'emerging.': [985], 'field': [991], 'suggest': [994], 'possibility': [996], 'customize': [998], 'particles': [999], 'organs.20Haque': [1002], 'A.K.M.A.': [1003], 'Dewerth': [1004], 'Antony': [1006], 'J.S.': [1007, 3432, 4054], 'Riethmüller': [1008], 'Schweizer': [1010], 'G.R.': [1011], 'Weinmann': [1012], 'Latifi': [1014], 'Yasar': [1016], 'Pedemonte': [1018], 'Sondo': [1020], 'al.Chemically': [1023], 'modified': [1024], 'hCFTR': [1025], 'mRNAs': [1026], 'recuperate': [1027], 'function': [1029, 2753, 3330], 'model': [1033, 2921], 'cystic': [1035, 1089, 1606], 'fibrosis.Sci.': [1036], 'Rep.': [1037, 4004, 4149], '8:': [1039, 2614, 3375, 3739], '16776Google': [1040], '21Connolly': [1042], 'Isaacs': [1044], 'Cheng': [1046], 'Asrani': [1048], 'K.H.': [1049], 'Subramanian': [1050], 'R.R.': [1051], 'SERPINA1': [1052], 'Treatment': [1056], 'Alpha-1': [1058], 'Antitrypsin': [1059], 'Deficiency.J.': [1060], 'Nucleic': [1061], 'Acids.': [1062], '2018:': [1064, 2129], '8247935Google': [1065], 'Based': [1067], 'our': [1069], 'research': [1070], 'interest': [1071], 'lungs,': [1073], 'focuses': [1076], 'disease,': [1083], 'especially': [1084], 'monogenetic': [1085], 'diseases,': [1086, 1102, 1585, 1958], 'fibrosis': [1090, 1631, 1682, 1711, 1859, 2152], '(CF)': [1091], 'surfactant': [1093, 3882], 'B': [1095], '(SP-B)': [1096], 'deficiency,': [1097], 'well': [1099], 'multifactorial': [1101], 'chronic': [1105, 1750, 1803, 1886, 2764, 2816], 'obstructive': [1106, 2817], 'pulmonary': [1107, 1346, 1426, 1681, 1692, 1957, 2035, 2075, 2252, 2652, 2765, 2818, 3964, 4033], 'disease': [1108, 2819], '(COPD)': [1109], 'asthma.': [1111, 2463], 'To': [1112], 'targeted': [1114], 'options,': [1116], 'structure': [1118, 2607], 'methods': [1120], 'reach': [1122], 'populations': [1126, 1138, 1165, 1560, 1896], 'critical.': [1128], 'Therefore,': [1129], 'them.': [1143], 'improvements': [1151], 'featured.': [1168], 'has': [1171, 2791, 2832], 'very': [1173], 'architecture': [1175], 'enable': [1177], 'efficient': [1178], 'oxygen': [1181], 'carbon': [1183], 'dioxide': [1184], 'required': [1185, 2032, 2468, 3272, 3574, 3693, 4030], 'oxidative': [1187], 'metabolism.': [1188], 'Inhaled': [1189], 'gases': [1190], 'travel': [1191], 'airway': [1194, 1288, 1341, 1375, 1454, 1632, 1868, 2205, 2216, 2247, 2391, 2709, 2747, 4070, 4190, 4219], 'tubes': [1195, 1864], 'via': [1196], 'trachea': [1197, 2392, 2399, 2438], 'bronchi': [1198], 'bronchioles': [1200], 'alveoli': [1203, 1457], 'enriched': [1204], 'blood': [1206], 'vessels,': [1207], 'primary': [1209, 2555, 2778, 2993, 3030, 3061, 3098, 3151, 3195, 3232, 3364, 3402, 3453, 3488, 3536, 3615, 3657, 3730, 3767], 'gas': [1212, 1224], 'exchange.': [1213], 'Inflation': [1214], 'deflation': [1216], 'prerequisite': [1222], 'exchange': [1225], 'at': [1226, 2955], 'alveoli.': [1228], 'process': [1230, 1717], 'multiple': [1232, 1848, 1894, 2278, 2506, 2952, 3815, 3859], 'components': [1233], 'like': [1234], 'extracellular': [1236], 'matrix,': [1237], 'smooth': [1238], 'cells,': [1240, 1296, 1300, 1302, 1304, 1310, 1315, 1393, 1395, 1417, 1566, 1905, 1988, 1995, 2270], 'cartilage': [1242], 'support': [1244], 'flexible': [1246], 'collagen': [1247], 'elastin': [1250, 1487], 'fiber': [1251], 'network': [1252, 2042, 4040], 'flexibility': [1254], 'during': [1255, 2460, 4097], 'inflation': [1256, 1471], 'deflation.': [1258], 'Precisely': [1259], 'regulated': [1260, 2166], 'surface': [1261], 'fluids,': [1262], 'electrolytes,': [1263], 'mechanical': [1265], 'activity': [1266], 'secretory': [1268, 3871], 'ciliated': [1270, 1301, 2672, 2751, 2923, 4114], 'determine': [1272], 'mucociliary': [1274, 2231, 2684, 3808, 3852], 'clearance,': [1275], 'whereas': [1276, 2874], 'other': [1279], 'hand': [1280], 'epithelium': [1282, 1289, 1342, 1401, 1633], 'maintains': [1283], 'barrier': [1285], 'function.': [1286], '(tracheal': [1290], 'bronchiolar)': [1292], 'consists': [1293, 1402], 'goblet': [1295, 1392, 2036, 2071, 2088, 4009, 4034], 'brush': [1297], 'tuft': [1299, 2326], 'basal': [1303, 1923], 'neuroendocrine': [1305], 'neuroepithelial': [1307], 'bodies,': [1308], 'club': [1309, 1925, 3912, 4246], 'lineage-negative': [1311], 'epithelial': [1312, 1376, 1439, 1755, 1808, 2068, 2325, 2649, 2731, 2865, 2924], 'progenitor': [1313, 4206], '(LNEP)': [1314], 'newly': [1318], 'identified': [1319, 3825], 'ionocytes.22Plasschaert': [1320], 'L.W.': [1321], 'Žilionis': [1322], 'Choo-Wing': [1324], 'Savova': [1326], 'Knehr': [1328], 'Roma': [1330], 'Klein': [1332], 'A.M.': [1333, 1768, 3050, 3121, 3129], 'Jaffe': [1334], 'A.B.': [1335], 'A': [1336, 2578, 3134], 'single-cell': [1337], 'atlas': [1338], 'reveals': [1343], 'CFTR-rich': [1345], 'ionocyte.Nature.': [1347], '560:': [1349, 1382], '377-381Google': [1350], '23Montoro': [1352], 'D.T.': [1353], 'Haber': [1354], 'A.L.': [1355, 3056], 'Biton': [1356], 'Vinarsky': [1358], 'Lin': [1360], 'Birket': [1362], 'S.E.': [1363, 1707, 2021, 4019], 'Yuan': [1364], 'Leung': [1368, 3943], 'H.M.': [1369, 2356, 3586], 'Villoria': [1370], 'al.A': [1373], 'revised': [1374], 'hierarchy': [1377], 'CFTR-expressing': [1379], 'ionocytes.Nature.': [1380], '319-324Google': [1383], 'ducts': [1386, 1455], 'submucosal': [1388, 1911, 2176], 'glands': [1389, 2177], 'consist': [1390], 'serous': [1394, 2168], 'myoepithelial': [1397], 'cells.': [1398], 'alveolar': [1400, 1405, 1413, 1436, 1548, 3936, 3953, 4075], 'primarily': [1403], 'type': [1406, 1414, 1437, 2329, 3954], 'I': [1407, 3955], '(ATI)': [1408], '(∼95%),': [1410], 'macrophages,': [1411], 'II': [1415, 1438, 3957], '(ATII)': [1416], 'close': [1419], 'association': [1420], 'capillary': [1422], 'endothelial': [1423], 'microcirculation.24Castranova': [1427], 'Rabovsky': [1429], 'Tucker': [1431], 'J.H.': [1432, 2897], 'Miles': [1433], 'P.R.': [1434], 'cell:': [1440], 'multifunctional': [1442], 'pneumocyte.Toxicol.': [1443], 'Appl.': [1444], 'Pharmacol.': [1445], '1988;': [1446], '93:': [1447, 3111, 3778], '472-483Scopus': [1448], '(126)': [1449], 'terminal': [1453, 4162], 'supported': [1459], 'fibroblasts': [1461], 'myofibroblasts': [1463], 'producing': [1464], 'extensive': [1465], 'elastin-collagen': [1466], 'networks,': [1467], 'which': [1468, 1567, 2100, 2243, 2964], 'help': [1469, 1568], 'deflation.25Noguchi': [1473], 'Reddy': [1475], 'Kursar': [1477], 'J.D.': [1478], 'Parks': [1479], 'W.C.': [1480], 'Mecham': [1481], 'R.P.': [1482], 'Smooth': [1483], 'isoactin': [1485], 'fetal': [1489], 'bovine': [1490], 'lung.Exp.': [1491], 'Lung': [1492], '537-552Google': [1496], '26Morrisey': [1498], 'E.E.': [1499, 3252], 'Hogan': [1500], 'B.L.': [1501], 'Preparing': [1502], 'breath:': [1506], 'cellular': [1509], 'mechanisms': [1510], 'development.Dev.': [1513], 'Cell.': [1514, 2588], '2010;': [1515, 2382, 2932, 3070], '18:': [1516, 2784], '8-23Google': [1517], '27Boström': [1519], 'Willetts': [1521], 'Pekny': [1523], 'Levéen': [1525], 'Lindahl': [1527], 'Hedstrand': [1529], 'Pekna': [1531], 'Hellström': [1533], 'Gebre-Medhin': [1535], 'Schalling': [1537], 'al.PDGF-A': [1540], 'signaling': [1541, 2371, 4068], 'critical': [1544, 2623], 'event': [1545], 'myofibroblast': [1549], 'development': [1550], 'alveogenesis.Cell.': [1552], '85:': [1554, 3548], '863-873Google': [1555], 'Other': [1557], 'important': [1558, 2180, 2293, 4211], 'include': [1561, 2965], 'stem': [1562], 'region-specific': [1570], 'protection': [1573], 'against': [1574], 'pathogens,': [1575, 1932], 'respectively.': [1576], 'Abnormalities': [1577], 'mechanics': [1580], 'observed': [1582], 'including': [1586, 1989, 3892], 'CF,28Hilliard': [1587], 'T.N.': [1588], 'Regamey': [1589], 'Shute': [1591], 'J.K.': [1592, 4116], 'Nicholson': [1593], 'A.G.': [1594], 'Alton': [1595], 'E.W.': [1596], 'Bush': [1597], 'Davies': [1599], 'J.C.': [1600, 1623, 3178], 'Airway': [1601, 1651, 1667, 2067, 2119, 2256, 4147], 'remodelling': [1602, 1690, 1709, 1748, 1801], 'children': [1604], 'fibrosis.Thorax.': [1607], '2007;': [1608, 1725, 3158], '62:': [1609], '1074-1080Google': [1610], '29Adam': [1612], 'Roux-Delrieu': [1614], 'Luczka': [1616], 'Bonnomet': [1618], 'Lesage': [1620], 'Mérol': [1622], 'Polette': [1624], 'Abély': [1626], 'Coraux': [1628], 'Cystic': [1630, 2123], 'remodelling:': [1634], 'involvement': [1635], 'inflammation.J.': [1637, 2077], 'Pathol.': [1638, 1724], '235:': [1640], '408-419Google': [1641], 'asthma,30Elias': [1643], 'Zhu': [1645], 'Z.': [1646], 'Chupp': [1647], 'Homer': [1649], 'R.J.': [1650], 'remodeling': [1652, 1668, 1773], 'asthma.J.': [1654], 'Clin.': [1655, 2049, 2078, 4047], 'Invest.': [1656, 2050, 2079, 4048], '104:': [1658, 3159], '1001-1006Google': [1659], '31Fehrenbach': [1661], 'Wagner': [1663], 'Wegmann': [1665], 'asthma:': [1670], 'what': [1671], 'really': [1672], 'matters.Cell': [1673], 'Tissue': [1674, 1689, 1694, 1747, 1800], '367:': [1677, 1697], '551-569Google': [1678], 'idiopathic': [1680], '(IPF),32Knudsen': [1683], 'Ruppert': [1685], 'Ochs': [1687], 'fibrosis.Cell': [1693], '607-626Google': [1698], '33Wallace': [1700], 'W.A.': [1701], 'Fitch': [1702], 'P.M.': [1703], 'Simpson': [1704], 'A.J.': [1705, 3180], 'Howie': [1706], 'Inflammation-associated': [1708], '-': [1715], 'end': [1720], 'point.Int.': [1721], 'Exp.': [1723], '88:': [1726], '103-110Google': [1727], 'COPD,34Pain': [1729], 'Bermudez': [1731, 1784], 'Lacoste': [1733, 1786], 'Royer': [1735, 1788], 'P.J.': [1736, 1789], 'Botturi': [1737, 1790], 'Tissot': [1739, 1792], 'Brouard': [1741, 1794], 'Eickelberg': [1743, 1796], 'Magnan': [1745, 1798], 'bronchial': [1751, 1804], 'diseases:': [1752, 1805], 'mesenchymal': [1757, 1810], 'phenotype.Eur.': [1758, 1811], 'Respir.': [1759, 1812, 2492, 2781, 2928, 3068, 4105, 4193], 'Rev.': [1760, 1813, 2782], '2014;': [1761, 1814, 3504, 3819, 3863], '118-130Google': [1763, 1816], '35Salazar': [1765], 'L.M.': [1766], 'Herrera': [1767], 'Fibrotic': [1769], 'response': [1770, 2009], 'tissue': [1772, 1831, 1856, 2253], 'COPD.Hai.': [1775], '2011;': [1776, 2445, 2613, 3294, 3336, 4109], '189:': [1777], '101-109Google': [1778], 'bronchiolitis': [1781], 'obliterans.34Pain': [1782], '36Sato': [1818], 'Keshavjee': [1820], 'Bronchiolitis': [1822], 'obliterans': [1823], 'syndrome:': [1824], 'alloimmune-dependent': [1825], '-independent': [1827], 'injury': [1828], 'aberrant': [1830], 'remodeling.Semin.': [1832], 'Thorac.': [1833, 2263, 2611], 'Cardiovasc.': [1834], 'Surg.': [1835], '2008;': [1836, 3581], '20:': [1837], '173-182Google': [1838], 'These': [1840, 1976, 2449], 'conditions': [1841], 'detrimental': [1843, 2838], 'involve': [1847], 'factors,': [1849], 'increased': [1852], 'resistance': [1853], 'lung;': [1862], 'collapsing': [1863], 'thickening': [1866], 'walls': [1869], 'mucus': [1872, 1884, 2047, 2086, 2202, 2212, 2828, 4045], 'overproduction;': [1873], 'ciliary': [1878, 2218, 2556, 2724, 2779, 2796, 2881, 2937, 2942, 2994, 3031, 3062, 3099, 3152, 3196, 3233, 3287, 3365, 3403, 3409, 3454, 3489, 3537, 3616, 3658, 3699, 3731, 3768], 'function,': [1879, 2963], 'resulting': [1880, 2940], 'airflow': [1882], 'obstruction,': [1883], 'plugging,': [1885], 'infection,': [1887], 'inflammatory': [1889, 2743], 'damages.': [1890], 'process,': [1893], 'undergo': [1897], 'remodeling,': [1898], 'contributing': [1900], 'symptoms.': [1903], 'Goblet': [1904, 1940, 1970], 'present': [1906], 'broncho-epithelia': [1909], 'glands,': [1912], 'mucins': [1914, 2187], '(MUC5B': [1915], 'MUC5AC),': [1917], 'they': [1919, 4165, 4223], 'differentiated': [1921], 'upon': [1927], 'stimuli': [1929], '(toxic': [1930], 'substances,': [1931], 'particles,': [1933], 'neural': [1935], 'signals).': [1939], 'only': [1944, 4159], 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'2914-2924Google': [2053, 4051], '39Rajavelu': [2055], 'integrates': [2070], 'Th2': [2076], '125:': [2081], '2021-2031Google': [2082], 'Hyper-production': [2084], 'metaplasia': [2090, 4072], 'characteristics': [2092], 'Th2-mediated': [2094], 'non-mediated': [2096], 'inflammation': [2097], '(pathogen': [2098], 'mediated),': [2099], 'leads': [2101, 2244], 'complications': [2103], 'CF,': [2105, 2221, 4230], 'COPD,': [2106, 2788, 4231], 'IPF.40De': [2108], 'Rose': [2109], 'Molloy': [2111], 'Gohy': [2113], 'Pilette': [2115], 'Greene': [2117], 'C.M.': [2118, 3468, 4094], 'Epithelium': [2120], 'Dysfunction': [2121], 'Fibrosis': [2124], 'COPD.Mediators': [2126], 'Inflamm.': [2127], '1309746Google': [2130], '41Wynn': [2132], 'T.A.': [2133, 2913], 'Cheever': [2134], 'A.W.': [2135, 4178], 'Jankovic': [2136], 'Poindexter': [2138], 'Caspar': [2140], 'Lewis': [2142], 'F.A.': [2143], 'Sher': [2144], 'An': [2146], 'IL-12-based': [2147], 'vaccination': [2148], 'method': [2149], 'induced': [2153, 3966], 'schistosome': [2155], 'infection.Nature.': [2156], '1995;': [2157], '376:': [2158], '594-596Google': [2159], 'fluids': [2162], 'hydration': [2164], 'line': [2171], 'acinar': [2173], 'region': [2174], 'pathology': [2183], 'CF.': [2185], 'precisely': [2189], 'balanced': [2190], 'fluid,': [2192], 'electrolyte': [2194], 'transport': [2195], 'enables': [2196], 'rapid': [2197], 'secretion': [2198, 2223], 'dispersal': [2200], 'onto': [2203], 'surfaces': [2206], 'movement': [2209], 'gel': [2213], 'up': [2214], 'activity.': [2219], 'chloride': [2225], 'bicarbonate': [2227], 'impaired,': [2229], 'disrupting': [2230, 3406], 'clearance': [2232, 2719, 3809, 3853], 'mutations': [2235, 2948, 2987, 3059, 3096, 3230, 3400, 3446, 3486, 3532, 3848], 'CF': [2237], 'transmembrane': [2238], 'conductance': [2239], 'regulator': [2240], '(CFTR),': [2242], 'recurrent': [2246, 2756], 'infections,': [2248, 2759], 'sinusitis,': [2249], 'bronchiectasis,': [2250], 'remodeling.42Whitsett': [2254], 'Epithelial': [2257, 2480, 4000], 'Differentiation': [2258, 3994], 'Mucociliary': [2260, 2634, 2718, 3441], 'Clearance.Ann.': [2261], 'Am.': [2262, 2610], 'S143-S148Google': [2267], 'Brush': [2269, 2286], 'containing': [2271, 3322], 'distinctive': [2272], 'apical': [2273], 'microvilli,': [2274], 'found': [2276], 'organs,': [2279], 'e.g.,': [2280], 'pancreas,': [2281], 'intestine,': [2282], 'nose,': [2283], 'trachea.': [2285], 'known': [2289], 'play': [2291, 4167], 'role': [2294, 2403, 3908, 4169, 4212, 4242], 'activating': [2296], 'intestine43Gerbe': [2303], 'Sidot': [2305], 'Smyth': [2307], 'D.J.': [2308], 'Ohmoto': [2309], 'Matsumoto': [2311], 'I.': [2312, 3125, 3258, 3357, 3719, 3845], 'Dardalhon': [2313], 'Cesses': [2315], 'Garnier': [2317], 'Pouzolles': [2319], 'Brulin': [2321], 'al.Intestinal': [2324], 'initiate': [2328, 2741], 'mucosal': [2331], 'immunity': [2332], 'helminth': [2334], 'parasites.Nature.': [2335], '2016;': [2336, 2496, 2783, 3925], '529:': [2337], '226-230Scopus': [2338], '(297)': [2339], 'nose': [2343], '(Tas2R': [2344], 'receptors),44Tizzano': [2345], 'Gulbransen': [2347], 'B.D.': [2348, 4133], 'Vandenbeuch': [2349], 'Clapp': [2351], 'Herman': [2353], 'J.P.': [2354], 'Sibhatu': [2355], 'Churchill': [2357], 'M.E.': [2358, 3048], 'Silver': [2359], 'W.L.': [2360], 'Kinnamon': [2361], 'S.C.': [2362, 3634], 'Finger': [2363], 'T.E.': [2364, 3165], 'Nasal': [2365], 'chemosensory': [2366, 2405, 2434], 'bitter': [2369], 'taste': [2370], 'detect': [2373], 'irritants': [2374], 'bacterial': [2376], 'signals.Proc.': [2377], '107:': [2383], '3210-3215Google': [2384], 'however,': [2386], 'similar': [2388], 'phenomenon': [2389], 'testing.': [2394], 'indicated': [2401], 'their': [2402, 2471, 2505], 'surveillance': [2408], 'respiratory': [2411, 2677, 2864, 3921, 4255], 'regulators.45Krasteva': [2412], 'Canning': [2414], 'B.J.': [2415], 'Hartmann': [2416], 'Veres': [2418], 'T.Z.': [2419], 'Papadakis': [2420], 'T.': [2421, 2647, 3222, 3558, 3792], 'Mühlfeld': [2422], 'Schliecker': [2424], 'Tallini': [2426], 'Y.N.': [2427], 'Braun': [2428], 'Hackstein': [2430], 'al.Cholinergic': [2433], 'regulate': [2439, 2618], 'breathing.Proc.': [2440], '9478-9483Google': [2447], 'might': [2450], 'responsible': [2452], 'transducing': [2454], 'signals': [2455], 'regulating': [2456], 'wheezing': [2457], 'coughing': [2459], 'episodes': [2461], 'However,': [2464, 4154], 'further': [2465], 'understand': [2470], 'role.46Gordon': [2472], 'E.D.': [2473], 'Locksley': [2474], 'R.M.': [2475], 'Fahy': [2476], 'J.V.': [2477, 3681], 'Cross-Talk': [2478], 'between': [2479], 'Cells': [2481, 3997, 4001, 4144], 'Type': [2483], 'Immune': [2485], 'Signaling.': [2486], 'Role': [2488], 'IL-25.Am.': [2490], 'Crit.': [2493, 4194], 'Care': [2494, 4195], 'Med.': [2495, 2821, 4196], '193:': [2497], '935-936Google': [2498], 'Ciliated': [2500, 2660], 'characterized': [2503], 'apical,': [2507], 'motile': [2508, 3328, 3816, 3860], 'cilia': [2509, 2544, 2706, 2814, 2846, 2889, 3329], 'composed': 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[2584], 'components.Mol.': [2587], 'Proteomics.': [2589], '1:': [2591], '451-465Scopus': [2592], '(346)': [2593], '49Ostrowski': [2596], 'Dutcher': [2598, 2770, 3722], 'S.K.': [2599, 2771, 3723], 'Lo': [2600], 'C.W.': [2601], 'Cilia': [2602, 2632], 'models': [2604], 'studying': [2606], 'function.Proc.': [2609], '423-429Google': [2615], 'coordinated': [2620], 'bidirectional': [2621], 'beating': [2622, 2797, 2809, 2882], 'particle': [2625], 'pathogen': [2627], 'clearance.50Bustamante-Marin': [2628], 'X.M.': [2629], 'Clearance.Cold': [2635], '9:': [2641], 'a028241Google': [2642], '51Whitsett': [2644], 'Alenghat': [2646], 'Respiratory': [2648], 'orchestrate': [2651], 'immunity.Nat.': [2654], 'Immunol.': [2655], '16:': [2657], '27-35Google': [2658], 'respond': [2662], 'both': [2664], 'physical52Sanderson': [2665], 'M.J.': [2666, 2704, 3428], 'Dirksen': [2667], 'E.R.': [2668], 'Mechanosensitivity': [2669], 'cultured': [2671], 'mammalian': [2676], 'tract:': [2678], 'implications': [2679], 'regulation': [2682], 'transport.Proc.': [2685], '1986;': [2690], '83:': [2691], '7302-7306Google': [2692], 'chemical53Shah': [2695], 'A.S.': [2696], 'Ben-Shahar': [2697], 'Moninger': [2699], 'T.O.': [2700], 'Kline': [2701], 'J.N.': [2702, 2857], 'Welsh': [2703], 'Motile': [2705], 'epithelia': [2710], 'chemosensory.Science.': [2712], '325:': [2714], '1131-1134Google': [2715], 'stimulation.': [2717], 'affected': [2722], 'dysfunction,': [2725], 'impaired': [2726], 'fluid': [2727], 'secretion,': [2728], 'disruption': [2729, 3492], 'lining,': [2733], 'lack': [2735], 'cough.': [2737], 'impairment': [2739], 'response,': [2744], 'damaging': [2745], 'epithelium.': [2748], 'Disruption': [2749], 'results': [2754], 'persistent': [2758], 'morbidity,': [2760], 'mortality': [2762], 'disorders.54Horani': [2766], 'Ferkol': [2768, 3344, 3708], 'T.W.': [2769, 3345, 3709, 3753], 'Brody': [2772, 3342, 3724], 'S.L.': [2773, 3343, 3725], 'Genetics': [2774], 'biology': [2776], 'dyskinesia.Paediatr.': [2780], '18-24Google': [2785], 'direct': [2789], 'evidence': [2790], 'provided': [2793], 'suppressed': [2795], 'nasal': [2799, 2813], 'epithelium55Yaghi': [2800], 'Zaman': [2802], 'Cox': [2804], 'Dolovich': [2806], 'Ciliary': [2808], 'depressed': [2811], 'subjects.Respir.': [2820], '106:': [2823], '1139-1147Google': [2824], 'normal': [2827, 3065, 3286, 3368, 4188], 'production.': [2829], 'Cigarette': [2830, 2860], 'smoking': [2831], 'shown': [2834], 'size': [2844], 'vitro,56Tamashiro': [2848], 'Xiong': [2850], 'Anselmo-Lima': [2852], 'W.T.': [2853], 'Kreindler': [2854], 'J.L.': [2855, 3426], 'Palmer': [2856], 'Cohen': [2858], 'N.A.': [2859], 'smoke': [2861, 2916], 'exposure': [2862, 2917], 'impairs': [2863], 'ciliogenesis.Am.': [2866], 'Rhinol.': [2868], 'Allergy.': [2869], '117-122Google': [2872], 'slight': [2878], 'increase': [2879], 'initially': [2883], 'significant': [2886], 'over': [2890], 'prolonged': [2891], 'time': [2892], 'observed.57Simet': [2894], 'S.M.': [2895], 'Sisson': [2896], 'Pavlik': [2898], 'Devasure': [2900], 'J.M.': [2901], 'Boyer': [2902], 'Liu': [2904, 3082, 3386], 'Kawasaki': [2906], 'Sharp': [2908], 'J.G.': [2909], 'Rennard': [2910], 'S.I.': [2911], 'Wyatt': [2912], 'Long-term': [2914], 'cigarette': [2915], 'function.Am.': [2926], 'Cell': [2929, 4106], 'Mol.': [2930, 4107], '43:': [2933, 3295, 3337], '635-640Google': [2934], 'Primary': [2936], 'dyskinesia': [2938, 2995, 3032, 3063, 3100, 3234, 3366, 3404, 3490, 3538, 3659, 3732, 3769], '(PCD)': [2939], 'dysfunction': [2943], 'caused': [2945], 'recessive': [2947], 'one': [2950], 'involved': [2954], 'different': [2956], 'points': [2957], 'cilium': [2959], 'structure,': [2960], 'assembly,': [2961], 'DNAI,58Guichard': [2966], 'Harricane': [2968], 'M.C.': [2969], 'Lafitte': [2970], 'J.J.': [2971], 'Godard': [2972], 'Zaegel': [2974], 'Tack': [2976], 'Lalau': [2978], 'Bouvagnet': [2980], 'Axonemal': [2982], 'intermediate-chain': [2984], '(DNAI1)': [2986], 'result': [2988, 3805, 3849], 'situs': [2990], 'inversus': [2991], '(Kartagener': [2996], 'syndrome).Am.': [2997], 'Hum.': [2999, 3108, 3199, 3242, 3457, 3502, 3545, 3664, 3775], 'Genet.': [3000, 3038, 3109, 3200, 3243, 3293, 3335, 3412, 3458, 3503, 3546, 3618, 3665, 3701, 3776, 3818], '2001;': [3001], '68:': [3002], '1030-1035Google': [3003], 'DNAH(5,59Olbrich': [3005], 'Häffner': [3007, 3514], 'Kispert': [3009, 3522], 'Völkel': [3011], 'Volz': [3013], 'Sasmaz': [3015], 'Reinhardt': [3017], 'Hennig': [3019], 'Lehrach': [3021], 'Konietzko': [3023], 'al.Mutations': [3026, 3607, 3646, 3802], 'DNAH5': [3028], 'cause': [3029, 3097, 3193, 3231, 3401, 3451, 3487, 3535, 3614, 3656], 'randomization': [3034, 3102, 3236], 'left-right': [3036, 3238, 3332], 'asymmetry.Nat.': [3037], '30:': [3040], '143-144Google': [3041], '1160Pifferi': [3043], 'Michelucci': [3045], 'Conidi': [3047], 'Cangiotti': [3049], 'Simi': [3051], 'Macchia': [3053], 'Boner': [3055], 'New': [3057], 'DNAH11': [3058], 'axonemal': [3066, 3579, 3609, 3695], 'ultrastructure.Eur.': [3067], '35:': [3071], '1413-1416Google': [3072], 'Scholar),': [3073, 3507, 3622], 'ARMC4,61Hjeij': [3074], 'Lindstrand': [3076], 'Francis': [3078, 3676], 'Zariwala': [3080, 3166, 3524], 'Damerla': [3086], 'Dougherty': [3088, 3473, 3678, 3760, 3799, 3838], 'G.W.': [3089, 3474, 3679, 3761, 3800, 3839], 'Abouhamed': [3090], 'Olbrich': [3092, 3314, 3510, 3555, 3604, 3797, 3836], 'al.ARMC4': [3095], 'left/right': [3104], 'body': [3105, 3239], 'asymmetry.Am.': [3106, 3240], '357-367Google': [3112], 'TXNDC3,62Duriez': [3114], 'Duquesnoy': [3116], 'Escudier': [3118], 'Bridoux': [3120], 'Escalier': [3122], 'Rayet': [3124], 'Marcos': [3126], 'Vojtek': [3128], 'Bercher': [3130], 'J.F.': [3131], 'Amselem': [3132], 'common': [3135], 'variant': [3136], 'combination': [3138], 'member': [3145], 'thioredoxin': [3148], 'family': [3149], 'causes': [3150, 3363, 3729], 'dyskinesia.Proc.': [3153], '3336-3341Google': [3160], 'HEATR2,63Horani': [3162], 'Druley': [3164], 'Patel': [3168], 'A.C.': [3169, 3250, 4120], 'Levinson': [3170], 'B.T.': [3171], 'Van': [3172, 4125], 'Arendonk': [3173], 'L.G.': [3174], 'Thornton': [3175], 'K.C.': [3176], 'Giacalone': [3177], 'Albee': [3179], 'Wilson': [3181, 3352, 3641], 'K.S.': [3182, 3353], 'al.Whole-exome': [3184], 'capture': [3185], 'sequencing': [3187, 3444], 'identifies': [3188, 3445], 'HEATR2': [3189], 'dyskinesia.Am.': [3197, 3455], '91:': [3202, 3245], '685-693Google': [3203], 'HYDIN,64Olbrich': [3205], 'Schmidts': [3207, 3396, 3520, 3587], 'Werner': [3209, 3842], 'Onoufriadis': [3211, 3465], 'Loges': [3213, 3312, 3388, 3477, 3559, 3589, 3672, 3787, 3832], 'N.T.': [3214, 3313, 3389, 3472, 3478, 3509, 3560, 3590, 3673, 3788, 3833], 'Raidt': [3215, 3840], 'Banki': [3217], 'N.F.': [3218, 3482], 'Shoemark': [3219], 'Burgoyne': [3221], 'Al': [3223, 3601], 'Turki': [3224], 'al.UK10K': [3227, 3484], 'ConsortiumRecessive': [3228], 'HYDIN': [3229], 'without': [3235], '672-684Google': [3246], 'CDC': [3248], '(39,65Merveille': [3249], 'Davis': [3251, 3433], 'Becker-Heck': [3253, 3380, 3512], 'Legendre': [3255], 'Amirav': [3257, 3356, 3718, 3844], 'Bataille': [3259], 'Belmont': [3261], 'Beydon': [3263], 'Billen': [3265], 'Clément': [3267], 'al.CCDC39': [3270], 'assembly': [3274, 3407, 3611, 3697], 'arms': [3278], 'regulatory': [3282], 'complex': [3283, 3499], 'motility': [3288], 'humans': [3290], 'dogs.Nat.': [3292], '72-78Google': [3296], '40,66Becker-Heck': [3298], 'Zohn': [3300], 'I.E.': [3301], 'Okabe': [3302], 'Pollock': [3304], 'Lenhart': [3306], 'K.B.': [3307], 'Sullivan-Brown': [3308], 'McSheene': [3310], 'Haeffner': [3316], 'al.The': [3319], 'coiled-coil': [3320], 'domain': [3321], 'CCDC40': [3324], 'essential': [3326], 'axis': [3333], 'formation.Nat.': [3334], '79-84Google': [3338], '65,67Horani': [3340], 'Shoseyov': [3346, 3710], 'Wasserman': [3348, 3712], 'M.G.': [3349, 3713, 4082], 'Ta-shma': [3350], 'Bayly': [3354], 'P.V.': [3355], 'Cohen-Cymberknoh': [3358, 3720], 'al.CCDC65': [3361], 'ultrastructure': [3369], 'hyperkinetic': [3371], 'cilia.PLoS': [3372], 'ONE.': [3373, 3737, 3971], 'e72299Google': [3376], '103,68Panizzi': [3378], 'J.R.': [3379, 4086], 'Castleman': [3382], 'V.H.': [3383, 3625], 'Al-Mutairi': [3384, 3748, 3783], 'D.A.': [3385, 3749, 3784, 4064], 'Pathak': [3390], 'Austin-Tse': [3392], 'Sheridan': [3394], 'al.CCDC103': [3399], 'arms.Nat.': [3411], '44:': [3414, 3620, 4110], '714-719Google': [3415], '114,69Knowles': [3417], 'M.R.': [3418], 'Leigh': [3419, 3526, 3750], 'M.W.': [3420, 3527, 3751], 'Huang': [3423], 'Carson': [3425], 'Hazucha': [3427], 'Yin': [3429, 3941, 3980], 'Berg': [3431], 'S.D.': [3434, 3436, 3757], 'Dell': [3435, 3756], 'al.Genetic': [3438], 'Disorders': [3439], 'Clearance': [3442], 'ConsortiumExome': [3443], 'CCDC114': [3448], '92:': [3460], '99-106Google': [3461], '15170Hjeij': [3463], 'Watson': [3467], 'Slagle': [3469, 3674], 'C.E.': [3470, 3675], 'Klena': [3471], 'Kurkowiak': [3475, 3746], 'Diggle': [3479], 'C.P.': [3480], 'Morante': [3481], 'ConsortiumCCDC151': [3485], 'outer': [3495], 'docking': [3498], 'formation.Am.': [3500], '95:': [3505], '257-274Google': [3506], 'DNAAF(1,71Loges': [3508], 'Heer': [3516], 'Reinhard': [3518], 'al.Deletions': [3529], 'point': [3531], 'LRRC50': [3534], 'defects.Am.': [3543], '883-889Google': [3549], '2,72Omran': [3551], 'Kobayashi': [3553], 'Tsukahara': [3557], 'Hagiwara': [3561], 'Q.': [3564, 3985, 4060], 'Leblond': [3565], "O'Toole": [3567], 'Hara': [3569], 'al.Ktu/PF13': [3572], 'pre-assembly': [3577], 'dyneins.Nature.': [3580], '456:': [3582], '611-616Google': [3583], '373Mitchison': [3585], 'Freshour': [3591], 'Dritsoula': [3593], 'Hirst': [3595, 3630], 'R.A.': [3596, 3631], "O'Callaghan": [3597], 'Blau': [3599], 'Dabbagh': [3602], 'factor': [3612], 'DNAAF3': [3613], 'dyskinesia.Nat.': [3617], '381-389Google': [3621], 'RHSP(4A,': [3623], '9),74Castleman': [3624], 'Romio': [3626], 'Chodhari': [3628], 'Castro': [3633], 'Parker': [3635], 'Ybot-Gonzalez': [3637], 'Emes': [3639], 'R.D.': [3640], 'S.W.': [3642], 'Wallis': [3643], 'radial': [3648], 'spoke': [3649], 'head': [3650], 'RSPH9': [3653], 'RSPH4A': [3655], 'central-microtubular-pair': [3661], 'abnormalities.Am.': [3662], '84:': [3667], '197-209Google': [3668], 'DYX1C1,75Tarkar': [3670], 'Tamayo': [3680], 'Shook': [3682], 'Cantino': [3684], 'Schwartz': [3686], 'Jahnke': [3688], 'al.UK10KDYX1C1': [3691], 'motility.Nat.': [3700], '45:': [3703], '995-1003Google': [3704], 'LRRC6,76Horani': [3706], 'Oren': [3714], 'Y.S.': [3715], 'Kerem': [3716], 'al.LRRC6': [3727], 'defects.PLoS': [3736], 'e59436Google': [3740], 'ZMYND10,77Zariwala': [3742], 'Gee': [3744], 'H.Y.': [3745], 'Hurd': [3752], 'Hjeij': [3754], 'Chaki': [3758], 'al.ZMYND10': [3763], 'mutated': [3765], 'interacts': [3771], 'LRRC6.Am.': [3773], '336-345Google': [3779], 'CCNO,78Wallmeier': [3781], 'C.T.': [3786], 'Pennekamp': [3789], 'Menchen': [3791], 'Ma': [3793, 3830], 'Shamseldin': [3795], 'H.E.': [3796], 'CCNO': [3804], 'congenital': [3807], 'disorder': [3810, 3854], 'reduced': [3812, 3856], 'generation': [3813, 3857], 'cilia.Nat.': [3817, 3861], '646-651Google': [3821], 'MCIDAS.79Boon': [3826], 'Wallmeier': [3828], 'Jaspers': [3834], 'al.MCIDAS': [3847], '5:': [3864], '4418Google': [3865], 'Club': [3867, 3996, 4203], 'columnar,': [3870], 'express': [3874], 'levels': [3876], 'cytochrome': [3878], 'P450-detoxifying': [3879], 'enzyme': [3880], 'CYP2F,': [3881], '(SP-A,': [3884], 'SP-B,': [3885], 'SP-D),': [3887], 'proteins,': [3891], 'defensins,': [3893], 'lactoferrin,': [3894], 'secretaglobins': [3896], '(SCGB1A1': [3897], 'SCGB3A1).80Rokicki': [3899], 'Rokicki': [3901, 4235], 'Wojtacha': [3903, 4237], 'Dżeljijli': [3905, 4239], 'importance': [3910, 4244], '(Clara': [3914, 4248], 'cells)': [3915, 4249], 'pathogenesis': [3918, 4252], 'some': [3920, 4254], 'diseases.Kardiochir.': [3922, 4256], 'Torakochirurgia': [3923], 'Pol.': [3924], '26-30Google': [3927], 'Upon': [3929], 'stimulus': [3930], 'injury,': [3932], 'differentiate': [3934], 'cells,81Zheng': [3937], 'Limmon': [3939], 'G.V.': [3940], 'N.H.': [3944], 'Yu': [3945], 'Chow': [3947, 3990], 'V.T.': [3948, 3991], 'Regeneration': [3951], 'Scgb1a1-expressing': [3960], 'following': [3962], 'severe': [3963], 'damage': [3965, 4227], 'bleomycin': [3968], 'influenza.PLoS': [3970], 'e48451Google': [3974], '82Zheng': [3976], 'Soh': [3978], 'B.S.': [3979], 'Hu': [3982], 'Choi': [3986], 'Han': [3988], 'Alveolar': [3999], 'Vitro.Sci.': [4003], '41661Google': [4007], 'cells,38Chen': [4010], '83Guseh': [4053], 'Bores': [4055], 'Stanger': [4057], 'B.Z.': [4058], 'Anderson': [4061], 'W.J.': [4062], 'Melton': [4063], 'Rajagopal': [4065], 'Notch': [4067], 'promotes': [4069], 'mucous': [4071], 'development.Development.': [4076], '136:': [4078], '1751-1759Google': [4079], '84Roy': [4081], 'Rahmani': [4083], 'Hernandez': [4085], 'Alexander': [4087], 'S.N.': [4088], 'Ehre': [4089], 'Ho': [4091], 'S.B.': [4092], 'Evans': [4093], 'Mucin': [4095], 'production': [4096], 'prenatal': [4098], 'postnatal': [4100], 'murine': [4101], 'development.Am.': [4103], '755-760Google': [4111], 'cells.85Watson': [4115], 'Rulands': [4117], 'Wilkinson': [4119], 'Wuidart': [4121], 'Ousset': [4123], 'Keymeulen': [4126], 'Göttgens': [4128], 'Blanpain': [4130], 'Simons': [4132], 'Rawlins': [4134], 'E.L.': [4135], 'Clonal': [4136], 'Dynamics': [4137], 'Reveal': [4138], 'Two': [4139], 'Distinct': [4140], 'Populations': [4141], 'Basal': [4143], 'Slow-Turnover': [4146], 'Epithelium.Cell': [4148], '12:': [4151], '90-101Google': [4152], 'humans,': [4156], 'localized': [4160], 'bronchioles,': [4163], 'may': [4166], 'maintenance': [4172], 'distal': [4174], 'bronchioles.86Boers': [4175], 'J.E.': [4176], 'Ambergen': [4177], 'Thunnissen': [4179], 'F.B.': [4180], 'Number': [4181], 'proliferation': [4183], 'clara': [4185], 'epithelium.Am.': [4191], '159:': [4198], '1585-1591Scopus': [4199], '(208)': [4200], 'plays': [4209], 'repair': [4215], 'epithelium,': [4220], 'and,': [4221], 'therefore,': [4222], 'connected': [4225], 'responses': [4228], 'IPF.80Rokicki': [4233]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2921986119', 'counts_by_year': [{'year': 2024, 'cited_by_count': 15}, {'year': 2023, 'cited_by_count': 24}, {'year': 2022, 'cited_by_count': 16}, {'year': 2021, 'cited_by_count': 15}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 2}], 'updated_date': '2024-12-10T17:11:17.379885', 'created_date': '2019-03-22'}