Publication Information

{'id': 'https://openalex.org/W2919957599', 'doi': 'https://doi.org/10.1176/appi.ajp.2018.18070881', 'title': 'No Support for Historical Candidate Gene or Candidate Gene-by-Interaction Hypotheses for Major Depression Across Multiple Large Samples', 'display_name': 'No Support for Historical Candidate Gene or Candidate Gene-by-Interaction Hypotheses for Major Depression Across Multiple Large Samples', 'publication_year': 2019, 'publication_date': '2019-03-08', 'ids': {'openalex': 'https://openalex.org/W2919957599', 'doi': 'https://doi.org/10.1176/appi.ajp.2018.18070881', 'mag': '2919957599', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/30845820', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6548317'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1176/appi.ajp.2018.18070881', 'pdf_url': 'https://ajp.psychiatryonline.org/doi/pdf/10.1176/appi.ajp.2018.18070881', 'source': {'id': 'https://openalex.org/S116025658', 'display_name': 'American Journal of Psychiatry', 'issn_l': '0002-953X', 'issn': ['0002-953X', '1535-7228'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316602', 'host_organization_name': 'American Psychiatric Association', 'host_organization_lineage': ['https://openalex.org/P4310316602'], 'host_organization_lineage_names': ['American Psychiatric Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://ajp.psychiatryonline.org/doi/pdf/10.1176/appi.ajp.2018.18070881', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5069656894', 'display_name': 'Richard Border', 'orcid': 'https://orcid.org/0000-0002-6293-2968'}, 'institutions': [{'id': 'https://openalex.org/I188538660', 'display_name': 'University of Colorado Boulder', 'ror': 'https://ror.org/02ttsq026', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I188538660']}, {'id': 'https://openalex.org/I114027177', 'display_name': 'University of North Carolina at Chapel Hill', 'ror': 'https://ror.org/0130frc33', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I114027177']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Richard Border', 'raw_affiliation_strings': ['The Institute for Behavioral Genetics (Border, Johnson, Evans, Smolen, Keller), the Department of Psychology and Neuroscience (Border, Berley, Keller), the Department of Applied Mathematics (Border), and the Department of Ecology and Evolutionary Biology (Evans), University of Colorado Boulder, Boulder; the Department of Psychiatry, Washington University School of Medicine, St. Louis (Johnson); the Department of Genetics and Psychiatry, University of North Carolina at Chapel Hill (Sullivan); and the...'], 'affiliations': [{'raw_affiliation_string': 'The Institute for Behavioral Genetics (Border, Johnson, Evans, Smolen, Keller), the Department of Psychology and Neuroscience (Border, Berley, Keller), the Department of Applied Mathematics (Border), and the Department of Ecology and Evolutionary Biology (Evans), University of Colorado Boulder, Boulder; the Department of Psychiatry, Washington University School of Medicine, St. Louis (Johnson); the Department of Genetics and Psychiatry, University of North Carolina at Chapel Hill (Sullivan); and the...', 'institution_ids': ['https://openalex.org/I188538660', 'https://openalex.org/I114027177']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012200474', 'display_name': 'Emma C. Johnson', 'orcid': 'https://orcid.org/0000-0003-0394-777X'}, 'institutions': [{'id': 'https://openalex.org/I188538660', 'display_name': 'University of Colorado Boulder', 'ror': 'https://ror.org/02ttsq026', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I188538660']}, {'id': 'https://openalex.org/I114027177', 'display_name': 'University of North Carolina at Chapel Hill', 'ror': 'https://ror.org/0130frc33', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I114027177']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Emma C. Johnson', 'raw_affiliation_strings': ['The Institute for Behavioral Genetics (Border, Johnson, Evans, Smolen, Keller), the Department of Psychology and Neuroscience (Border, Berley, Keller), the Department of Applied Mathematics (Border), and the Department of Ecology and Evolutionary Biology (Evans), University of Colorado Boulder, Boulder; the Department of Psychiatry, Washington University School of Medicine, St. Louis (Johnson); the Department of Genetics and Psychiatry, University of North Carolina at Chapel Hill (Sullivan); and the...'], 'affiliations': [{'raw_affiliation_string': 'The Institute for Behavioral Genetics (Border, Johnson, Evans, Smolen, Keller), the Department of Psychology and Neuroscience (Border, Berley, Keller), the Department of Applied Mathematics (Border), and the Department of Ecology and Evolutionary Biology (Evans), University of Colorado Boulder, Boulder; the Department of Psychiatry, Washington University School of Medicine, St. Louis (Johnson); the Department of Genetics and Psychiatry, University of North Carolina at Chapel Hill (Sullivan); and the...', 'institution_ids': ['https://openalex.org/I188538660', 'https://openalex.org/I114027177']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083763530', 'display_name': 'Luke M. Evans', 'orcid': 'https://orcid.org/0000-0002-7458-1720'}, 'institutions': [{'id': 'https://openalex.org/I188538660', 'display_name': 'University of Colorado Boulder', 'ror': 'https://ror.org/02ttsq026', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I188538660']}, {'id': 'https://openalex.org/I114027177', 'display_name': 'University of North Carolina at Chapel Hill', 'ror': 'https://ror.org/0130frc33', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I114027177']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Luke M. Evans', 'raw_affiliation_strings': ['The Institute for Behavioral Genetics (Border, Johnson, Evans, Smolen, Keller), the Department of Psychology and Neuroscience (Border, Berley, Keller), the Department of Applied Mathematics (Border), and the Department of Ecology and Evolutionary Biology (Evans), University of Colorado Boulder, Boulder; the Department of Psychiatry, Washington University School of Medicine, St. Louis (Johnson); the Department of Genetics and Psychiatry, University of North Carolina at Chapel Hill (Sullivan); and the...'], 'affiliations': [{'raw_affiliation_string': 'The Institute for Behavioral Genetics (Border, Johnson, Evans, Smolen, Keller), the Department of Psychology and Neuroscience (Border, Berley, Keller), the Department of Applied Mathematics (Border), and the Department of Ecology and Evolutionary Biology (Evans), University of Colorado Boulder, Boulder; the Department of Psychiatry, Washington University School of Medicine, St. Louis (Johnson); the Department of Genetics and Psychiatry, University of North Carolina at Chapel Hill (Sullivan); and the...', 'institution_ids': ['https://openalex.org/I188538660', 'https://openalex.org/I114027177']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085447170', 'display_name': 'Andrew Smolen', 'orcid': 'https://orcid.org/0000-0002-9030-0562'}, 'institutions': [{'id': 'https://openalex.org/I188538660', 'display_name': 'University of Colorado Boulder', 'ror': 'https://ror.org/02ttsq026', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I188538660']}, {'id': 'https://openalex.org/I114027177', 'display_name': 'University of North Carolina at Chapel Hill', 'ror': 'https://ror.org/0130frc33', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I114027177']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Andrew Smolen', 'raw_affiliation_strings': ['The Institute for Behavioral Genetics (Border, Johnson, Evans, Smolen, Keller), the Department of Psychology and Neuroscience (Border, Berley, Keller), the Department of Applied Mathematics (Border), and the Department of Ecology and Evolutionary Biology (Evans), University of Colorado Boulder, Boulder; the Department of Psychiatry, Washington University School of Medicine, St. Louis (Johnson); the Department of Genetics and Psychiatry, University of North Carolina at Chapel Hill (Sullivan); and the...'], 'affiliations': [{'raw_affiliation_string': 'The Institute for Behavioral Genetics (Border, Johnson, Evans, Smolen, Keller), the Department of Psychology and Neuroscience (Border, Berley, Keller), the Department of Applied Mathematics (Border), and the Department of Ecology and Evolutionary Biology (Evans), University of Colorado Boulder, Boulder; the Department of Psychiatry, Washington University School of Medicine, St. Louis (Johnson); the Department of Genetics and Psychiatry, University of North Carolina at Chapel Hill (Sullivan); and the...', 'institution_ids': ['https://openalex.org/I188538660', 'https://openalex.org/I114027177']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017017519', 'display_name': 'Noah Berley', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I188538660', 'display_name': 'University of Colorado Boulder', 'ror': 'https://ror.org/02ttsq026', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I188538660']}, {'id': 'https://openalex.org/I114027177', 'display_name': 'University of North Carolina at Chapel Hill', 'ror': 'https://ror.org/0130frc33', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I114027177']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Noah Berley', 'raw_affiliation_strings': ['The Institute for Behavioral Genetics (Border, Johnson, Evans, Smolen, Keller), the Department of Psychology and Neuroscience (Border, Berley, Keller), the Department of Applied Mathematics (Border), and the Department of Ecology and Evolutionary Biology (Evans), University of Colorado Boulder, Boulder; the Department of Psychiatry, Washington University School of Medicine, St. Louis (Johnson); the Department of Genetics and Psychiatry, University of North Carolina at Chapel Hill (Sullivan); and the...'], 'affiliations': [{'raw_affiliation_string': 'The Institute for Behavioral Genetics (Border, Johnson, Evans, Smolen, Keller), the Department of Psychology and Neuroscience (Border, Berley, Keller), the Department of Applied Mathematics (Border), and the Department of Ecology and Evolutionary Biology (Evans), University of Colorado Boulder, Boulder; the Department of Psychiatry, Washington University School of Medicine, St. Louis (Johnson); the Department of Genetics and Psychiatry, University of North Carolina at Chapel Hill (Sullivan); and the...', 'institution_ids': ['https://openalex.org/I188538660', 'https://openalex.org/I114027177']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061802355', 'display_name': 'Patrick F. Sullivan', 'orcid': 'https://orcid.org/0000-0002-6619-873X'}, 'institutions': [{'id': 'https://openalex.org/I188538660', 'display_name': 'University of Colorado Boulder', 'ror': 'https://ror.org/02ttsq026', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I188538660']}, {'id': 'https://openalex.org/I114027177', 'display_name': 'University of North Carolina at Chapel Hill', 'ror': 'https://ror.org/0130frc33', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I114027177']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Patrick F. Sullivan', 'raw_affiliation_strings': ['The Institute for Behavioral Genetics (Border, Johnson, Evans, Smolen, Keller), the Department of Psychology and Neuroscience (Border, Berley, Keller), the Department of Applied Mathematics (Border), and the Department of Ecology and Evolutionary Biology (Evans), University of Colorado Boulder, Boulder; the Department of Psychiatry, Washington University School of Medicine, St. Louis (Johnson); the Department of Genetics and Psychiatry, University of North Carolina at Chapel Hill (Sullivan); and the...'], 'affiliations': [{'raw_affiliation_string': 'The Institute for Behavioral Genetics (Border, Johnson, Evans, Smolen, Keller), the Department of Psychology and Neuroscience (Border, Berley, Keller), the Department of Applied Mathematics (Border), and the Department of Ecology and Evolutionary Biology (Evans), University of Colorado Boulder, Boulder; the Department of Psychiatry, Washington University School of Medicine, St. Louis (Johnson); the Department of Genetics and Psychiatry, University of North Carolina at Chapel Hill (Sullivan); and the...', 'institution_ids': ['https://openalex.org/I188538660', 'https://openalex.org/I114027177']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5043052935', 'display_name': 'Matthew C. Keller', 'orcid': 'https://orcid.org/0000-0002-6075-9882'}, 'institutions': [{'id': 'https://openalex.org/I188538660', 'display_name': 'University of Colorado Boulder', 'ror': 'https://ror.org/02ttsq026', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I188538660']}, {'id': 'https://openalex.org/I114027177', 'display_name': 'University of North Carolina at Chapel Hill', 'ror': 'https://ror.org/0130frc33', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I114027177']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Matthew C. Keller', 'raw_affiliation_strings': ['The Institute for Behavioral Genetics (Border, Johnson, Evans, Smolen, Keller), the Department of Psychology and Neuroscience (Border, Berley, Keller), the Department of Applied Mathematics (Border), and the Department of Ecology and Evolutionary Biology (Evans), University of Colorado Boulder, Boulder; the Department of Psychiatry, Washington University School of Medicine, St. Louis (Johnson); the Department of Genetics and Psychiatry, University of North Carolina at Chapel Hill (Sullivan); and the...'], 'affiliations': [{'raw_affiliation_string': 'The Institute for Behavioral Genetics (Border, Johnson, Evans, Smolen, Keller), the Department of Psychology and Neuroscience (Border, Berley, Keller), the Department of Applied Mathematics (Border), and the Department of Ecology and Evolutionary Biology (Evans), University of Colorado Boulder, Boulder; the Department of Psychiatry, Washington University School of Medicine, St. Louis (Johnson); the Department of Genetics and Psychiatry, University of North Carolina at Chapel Hill (Sullivan); and the...', 'institution_ids': ['https://openalex.org/I188538660', 'https://openalex.org/I114027177']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 71.506, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 543, 'citation_normalized_percentile': {'value': 0.99991, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '176', 'issue': '5', 'first_page': '376', 'last_page': '387'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11577', 'display_name': 'Cognitive Abilities and Testing', 'score': 0.9919, 'subfield': {'id': 'https://openalex.org/subfields/3205', 'display_name': 'Experimental and Cognitive Psychology'}, 'field': {'id': 'https://openalex.org/fields/32', 'display_name': 'Psychology'}, 'domain': {'id': 'https://openalex.org/domains/2', 'display_name': 'Social Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11577', 'display_name': 'Cognitive Abilities and Testing', 'score': 0.9919, 'subfield': {'id': 'https://openalex.org/subfields/3205', 'display_name': 'Experimental and Cognitive Psychology'}, 'field': {'id': 'https://openalex.org/fields/32', 'display_name': 'Psychology'}, 'domain': {'id': 'https://openalex.org/domains/2', 'display_name': 'Social Sciences'}}, {'id': 'https://openalex.org/T10261', 'display_name': 'Genetic Associations and Epidemiology', 'score': 0.9894, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10182', 'display_name': 'Child and Adolescent Psychosocial and Emotional Development', 'score': 0.9751, 'subfield': {'id': 'https://openalex.org/subfields/3203', 'display_name': 'Clinical Psychology'}, 'field': {'id': 'https://openalex.org/fields/32', 'display_name': 'Psychology'}, 'domain': {'id': 'https://openalex.org/domains/2', 'display_name': 'Social Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/candidate-gene', 'display_name': 'Candidate gene', 'score': 0.9006971}, {'id': 'https://openalex.org/keywords/population-stratification', 'display_name': 'Population stratification', 'score': 0.50068426}, {'id': 'https://openalex.org/keywords/depression', 'display_name': 'Depression', 'score': 0.42191187}, {'id': 'https://openalex.org/keywords/moderation', 'display_name': 'Moderation', 'score': 0.42095593}], 'concepts': [{'id': 'https://openalex.org/C69991583', 'wikidata': 'https://www.wikidata.org/wiki/Q1423575', 'display_name': 'Candidate gene', 'level': 3, 'score': 0.9006971}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.51497966}, {'id': 'https://openalex.org/C166976648', 'wikidata': 'https://www.wikidata.org/wiki/Q7229824', 'display_name': 'Population stratification', 'level': 5, 'score': 0.50068426}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.45455965}, {'id': 'https://openalex.org/C2908647359', 'wikidata': 'https://www.wikidata.org/wiki/Q2625603', 'display_name': 'Population', 'level': 2, 'score': 0.42309695}, {'id': 'https://openalex.org/C2776867660', 'wikidata': 'https://www.wikidata.org/wiki/Q1814941', 'display_name': 'Depression (economics)', 'level': 2, 'score': 0.42191187}, {'id': 'https://openalex.org/C93225998', 'wikidata': 'https://www.wikidata.org/wiki/Q1941972', 'display_name': 'Moderation', 'level': 2, 'score': 0.42095593}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.37092677}, {'id': 'https://openalex.org/C70410870', 'wikidata': 'https://www.wikidata.org/wiki/Q199906', 'display_name': 'Clinical psychology', 'level': 1, 'score': 0.3453672}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.25756225}, {'id': 'https://openalex.org/C135763542', 'wikidata': 'https://www.wikidata.org/wiki/Q106016', 'display_name': 'Genotype', 'level': 3, 'score': 0.23811337}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.18705171}, {'id': 'https://openalex.org/C153209595', 'wikidata': 'https://www.wikidata.org/wiki/Q501128', 'display_name': 'Single-nucleotide polymorphism', 'level': 4, 'score': 0.15463063}, {'id': 'https://openalex.org/C77805123', 'wikidata': 'https://www.wikidata.org/wiki/Q161272', 'display_name': 'Social psychology', 'level': 1, 'score': 0.09268689}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C139719470', 'wikidata': 'https://www.wikidata.org/wiki/Q39680', 'display_name': 'Macroeconomics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C162324750', 'wikidata': 'https://www.wikidata.org/wiki/Q8134', 'display_name': 'Economics', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000076783', 'descriptor_name': 'Adverse Childhood Experiences', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D003865', 'descriptor_name': 'Depressive Disorder, Major', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D059647', 'descriptor_name': 'Gene-Environment Interaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000067073', 'descriptor_name': 'Psychological Trauma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D012959', 'descriptor_name': 'Socioeconomic Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D003865', 'descriptor_name': 'Depressive Disorder, Major', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056726', 'descriptor_name': 'Genetic Association Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010641', 'descriptor_name': 'Phenotype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011110', 'descriptor_name': 'Polymorphism, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012008', 'descriptor_name': 'Recurrence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015203', 'descriptor_name': 'Reproducibility of Results', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012720', 'descriptor_name': 'Severity of Illness Index', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1176/appi.ajp.2018.18070881', 'pdf_url': 'https://ajp.psychiatryonline.org/doi/pdf/10.1176/appi.ajp.2018.18070881', 'source': {'id': 'https://openalex.org/S116025658', 'display_name': 'American Journal of Psychiatry', 'issn_l': '0002-953X', 'issn': ['0002-953X', '1535-7228'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316602', 'host_organization_name': 'American Psychiatric Association', 'host_organization_lineage': ['https://openalex.org/P4310316602'], 'host_organization_lineage_names': ['American Psychiatric Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc6548317', 'pdf_url': 'https://europepmc.org/articles/pmc6548317?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548317', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://doi.org/10.17615/8hef-8a84', 'pdf_url': 'https://cdr.lib.unc.edu/downloads/vm40z3972', 'source': {'id': 'https://openalex.org/S4306401075', 'display_name': 'Carolina Digital Repository (University of North Carolina at Chapel Hill)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I114027177', 'host_organization_name': 'University of North Carolina at Chapel Hill', 'host_organization_lineage': ['https://openalex.org/I114027177'], 'host_organization_lineage_names': ['University of North Carolina at Chapel Hill'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/30845820', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1176/appi.ajp.2018.18070881', 'pdf_url': 'https://ajp.psychiatryonline.org/doi/pdf/10.1176/appi.ajp.2018.18070881', 'source': {'id': 'https://openalex.org/S116025658', 'display_name': 'American Journal of Psychiatry', 'issn_l': '0002-953X', 'issn': ['0002-953X', '1535-7228'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316602', 'host_organization_name': 'American Psychiatric Association', 'host_organization_lineage': ['https://openalex.org/P4310316602'], 'host_organization_lineage_names': ['American Psychiatric Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 57, 'referenced_works': ['https://openalex.org/W1589843265', 'https://openalex.org/W1601856453', 'https://openalex.org/W1894736765', 'https://openalex.org/W1966758272', 'https://openalex.org/W1969470176', 'https://openalex.org/W1984455353', 'https://openalex.org/W1985464233', 'https://openalex.org/W1987942611', 'https://openalex.org/W1991302346', 'https://openalex.org/W1992204010', 'https://openalex.org/W2000151841', 'https://openalex.org/W2000460373', 'https://openalex.org/W2000904449', 'https://openalex.org/W2005534453', 'https://openalex.org/W2015093703', 'https://openalex.org/W2028142313', 'https://openalex.org/W2031024128', 'https://openalex.org/W2040259741', 'https://openalex.org/W2040600205', 'https://openalex.org/W2051314902', 'https://openalex.org/W2055245513', 'https://openalex.org/W2060015298', 'https://openalex.org/W2082704080', 'https://openalex.org/W2087414280', 'https://openalex.org/W2088842558', 'https://openalex.org/W2099610622', 'https://openalex.org/W2101357408', 'https://openalex.org/W2102521965', 'https://openalex.org/W2106631668', 'https://openalex.org/W2114850508', 'https://openalex.org/W2121955249', 'https://openalex.org/W2123466824', 'https://openalex.org/W2124916392', 'https://openalex.org/W2131533686', 'https://openalex.org/W2132322340', 'https://openalex.org/W2140660757', 'https://openalex.org/W2144875296', 'https://openalex.org/W2150090706', 'https://openalex.org/W2155226911', 'https://openalex.org/W2156104108', 'https://openalex.org/W2162196924', 'https://openalex.org/W2167459234', 'https://openalex.org/W2168463527', 'https://openalex.org/W2195783463', 'https://openalex.org/W2345597444', 'https://openalex.org/W2526501380', 'https://openalex.org/W2528374605', 'https://openalex.org/W2529241974', 'https://openalex.org/W2587960748', 'https://openalex.org/W2589114874', 'https://openalex.org/W2591920123', 'https://openalex.org/W2735838525', 'https://openalex.org/W2738082385', 'https://openalex.org/W2765504358', 'https://openalex.org/W2768889016', 'https://openalex.org/W2949141189', 'https://openalex.org/W4247894378'], 'related_works': ['https://openalex.org/W3033548456', 'https://openalex.org/W2954044368', 'https://openalex.org/W2806714088', 'https://openalex.org/W2385813177', 'https://openalex.org/W2275577754', 'https://openalex.org/W2078815200', 'https://openalex.org/W2029056863', 'https://openalex.org/W1965800774', 'https://openalex.org/W1592611938', 'https://openalex.org/W1516251615'], 'abstract_inverted_index': {'Objective:': [0], 'Interest': [1], 'in': [2, 182, 190, 221], 'candidate': [3, 6, 35, 82, 127, 143, 179, 209, 224], 'gene': [4, 83, 128, 180, 225], 'and': [5, 47, 62, 89, 107, 213], 'gene-by-environment': [7], 'interaction': [8], 'hypotheses': [9, 206], 'regarding': [10], 'major': [11], 'depressive': [12], 'disorder': [13], 'remains': [14], 'strong': [15], 'despite': [16], 'controversy': [17], 'surrounding': [18], 'the': [19, 29, 73, 201, 215, 222], 'validity': [20], 'of': [21, 78, 95, 98, 193, 218], 'previous': [22, 177], 'findings.': [23, 169], 'In': [24], 'response': [25], 'to': [26, 53, 69, 164, 229], 'this': [27], 'controversy,': [28], 'present': [30], 'investigation': [31], 'empirically': [32], 'identified': [33], '18': [34], 'genes': [36, 144, 210], 'for': [37, 50, 125, 166], 'depression': [38, 54, 99, 132, 142, 150, 178, 208, 223], 'that': [39, 158, 204, 214], 'have': [40], 'been': [41], 'studied': [42], '10': [43], 'or': [44, 112, 134], 'more': [45, 147], 'times': [46], 'examined': [48, 198], 'evidence': [49, 122], 'their': [51], 'relevance': [52], 'phenotypes.': [55], 'Methods:': [56], 'Utilizing': [57], 'data': [58], 'from': [59, 67], 'large': [60, 184, 216], 'population-based': [61], 'case-control': [63], 'samples': [64, 191], '(Ns': [65], 'ranging': [66], '62,138': [68], '443,264': [70], 'across': [71, 92], 'subsamples),': [72], 'authors': [74, 156], 'conducted': [75], 'a': [76, 93, 140], 'series': [77], 'preregistered': [79], 'analyses': [80], 'examining': [81], 'polymorphism': [84, 129], 'main': [85], 'effects,': [86], 'polymorphism-by-environment': [87, 136], 'interactions,': [88], 'gene-level': [90], 'effects': [91, 186], 'number': [94, 217], 'operational': [96], 'definitions': [97], '(e.g.,': [100, 110], 'lifetime': [101], 'diagnosis,': [102], 'current': [103], 'severity,': [104], 'episode': [105], 'recurrence)': [106], 'environmental': [108], 'moderators': [109], 'sexual': [111], 'physical': [113], 'abuse': [114], 'during': [115], 'childhood,': [116], 'socioeconomic': [117], 'adversity).': [118], 'Results:': [119], 'No': [120], 'clear': [121], 'was': [123], 'found': [124], 'any': [126, 135], 'associations': [130, 219], 'with': [131, 149], 'phenotypes': [133, 151], 'moderator': [137], 'effects.': [138], 'As': [139], 'set,': [141], 'were': [145, 211], 'no': [146], 'associated': [148], 'than': [152, 196], 'noncandidate': [153], 'genes.': [154], 'The': [155, 171], 'demonstrate': [157], 'phenotypic': [159], 'measurement': [160], 'error': [161], 'is': [162], 'unlikely': [163], 'account': [165], 'these': [167], 'null': [168], 'Conclusions:': [170], 'study': [172], 'results': [173, 202], 'do': [174], 'not': [175], 'support': [176], 'findings,': [181], 'which': [183], 'genetic': [185], 'are': [187, 227], 'frequently': [188], 'reported': [189, 220], 'orders': [192], 'magnitude': [194], 'smaller': [195], 'those': [197], 'here.': [199], 'Instead,': [200], 'suggest': [203], 'early': [205], 'about': [207], 'incorrect': [212], 'literature': [226], 'likely': [228], 'be': [230], 'false': [231], 'positives.': [232]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2919957599', 'counts_by_year': [{'year': 2024, 'cited_by_count': 65}, {'year': 2023, 'cited_by_count': 85}, {'year': 2022, 'cited_by_count': 88}, {'year': 2021, 'cited_by_count': 109}, {'year': 2020, 'cited_by_count': 122}, {'year': 2019, 'cited_by_count': 65}, {'year': 2017, 'cited_by_count': 1}], 'updated_date': '2024-12-22T05:11:40.137593', 'created_date': '2019-03-11'}