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'functional': [28, 128, 201], 'rescue': [29], 'and': [30, 55, 60, 154, 203, 213], 'full': [31], 'disease': [32], 'correction.': [33], 'Therefore,': [34], 'we': [35, 162], 'explored': [36], 'the': [37, 41, 63, 99, 109, 151, 205], 'potential': [38, 155, 208], 'combining': [40], 'benefits': [42], 'dystrophin': [44, 56, 71, 117, 121, 169], 'with': [45, 115, 174], 'increases': [46], 'utrophin,': [48], 'an': [49, 147], 'autosomal': [50], 'paralogue': [51], 'Utrophin': [54], 'can': [57], 'be': [58, 106], 'co-expressed': [59], 'co-localized': [61], 'at': [62, 98], 'same': [64], 'muscle': [65, 180], 'membrane.': [66], 'Wild-type': [67], '(wt)': [68], 'levels': [69, 84, 177, 184], 'not': [73, 126], 'significantly': [74], 'affected': [75, 112], 'moderate': [78], 'increase': [79], 'utrophin': [81, 86, 102, 132, 176], 'whereas': [82], 'higher': [83], 'reduce': [87], 'wt': [88, 123, 134, 168, 183], 'dystrophin,': [89], 'suggesting': [90], 'finite': [92], 'number': [93], 'actin': [95], 'binding': [96], 'sites': [97], 'sarcolemma.': [100], 'Thus,': [101, 194], 'upregulation': [103], 'strategies': [104], 'may': [105], 'applied': [107], 'to': [108, 182], 'more': [110], 'mildly': [111], 'Becker': [113], 'patients': [114], 'lower': [116], 'levels.': [118], 'Whereas': [119], 'increased': [120, 175], 'animals': [124], 'does': [125], 'offer': [127], 'improvement,': [129], 'overexpression': [130], 'mice': [135], 'results': [136, 198], 'significant': [139], 'supra-functional': [140], 'benefit': [141, 149, 188, 202], 'over': [142], 'wt.': [143], 'These': [144], 'findings': [145], 'highlight': [146], 'additive': [148, 200], 'combined': [152], 'therapy': [153, 197], 'new': [156], 'unique': [157], 'roles': [158], 'utrophin.': [160], 'Finally,': [161], 'show': [163], '30%': [165], 'restoration': [166], 'levels,': [170], 'using': [171], 'exon-skipping,': [172], 'together': [173], 'restores': [178], 'dystrophic': [179], 'function': [181], 'offering': [185], 'greater': [186], 'than': [189], 'either': [190], 'single': [191], 'approach': [192], 'alone.': [193], 'this': [195], 'combination': [196], 'paves': [204], 'way': [206], 'for': [207], 'future': [209], 'combinations': [210], 'dystrophin-': [212], 'utrophin-based': [214], 'strategies.': [215]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2918837467', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 9}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 12}, {'year': 2020, 'cited_by_count': 10}, {'year': 2019, 'cited_by_count': 1}], 'updated_date': '2024-09-14T15:45:13.687284', 'created_date': '2019-03-11'}