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1946, 1977, 2075, 2179, 2554, 2635, 2974, 3854, 3921, 3990], 'ISI': [665], 'Web': [666, 2276], 'Science).': [668], 'recent': [670, 715, 3121], 'years,': [671, 950], 'undergone': [676], 'some': [677], 'major': [678, 687, 757, 1631], 'changes': [679, 1819], 'addition': [682], 'new': [684, 734, 995, 1047], 'chapters': [685, 711], 'updates': [688], 'across': [689], 'multiple': [690], 'areas.': [691], 'For': [692, 2062, 3026], 'this': [693, 788, 1433, 1798, 2284, 2314, 2757, 2864, 3044, 3117], "year's": [694, 789, 2294], 'edition,': [695], 'Committee,': [698, 2229], 'which': [699, 951, 1429, 2155, 2663], 'produces': [700], 'document': [702, 2865, 3045], 'AHA,': [705, 2225], 'updated': [706], 'current': [710, 1268, 1874, 2054, 2105, 2250], 'nationally': [716], 'representative': [717], 'inclusion': [720], 'relevant': [722], 'articles': [723], 'over': [727, 1603], 'past': [729, 1510], 'year': [730, 3095, 3122], 'added': [732], 'chapter': [735], 'detailing': [736], 'how': [737], 'family': [738], 'history': [739], 'genetics': [741], 'play': [742], 'role': [744], 'cardiovascular': [746, 762, 1632, 2038, 2057, 2069, 3192, 3474], '(CVD)': [748], 'risk.': [749], 'Also,': [750], '2011': [752, 1398, 1857, 2779, 4141, 4149], 'source': [758], 'monitoring': [760], 'both': [761], 'health': [763, 1585, 2151, 2169], 'population,': [768], 'focus': [771, 1876], 'progress': [773], 'toward': [774], 'achievement': [775], "AHA's": [778, 1948, 1966], '2020': [779], 'Impact': [780, 3466], 'Goals.': [781], 'Below': [782], 'are': [783, 1056, 1062, 1209, 1215, 1442, 1459, 1478, 1490, 1505, 1801, 1944, 2006, 2032, 2322, 2670, 2759, 2835, 3046, 3062, 3107, 3340], 'few': [785], 'highlights': [786], 'Update.Death': [790], 'Rates': [791], 'CVD': [793, 808, 860, 869, 908, 926, 943, 1571, 2133, 2217], 'Have': [794], 'Declined,': [795], 'Yet': [796], 'Burden': [798], 'Remains': [801, 1137], 'HighThe': [802], '2007': [803, 866, 898, 929, 981, 1068, 2086, 2141, 2258], 'overall': [804], 'death': [805, 857, 915, 1102, 1119], 'rate': [806, 858, 900, 1103, 1709], '(International': [809], 'Classification': [810], 'Diseases': [812], '10,': [813], 'I00–I99)': [814], 'was': [815, 982, 1286, 1296, 2196], '251.2': [816], 'per': [817, 824, 831, 838, 846, 1730, 1838], '100': [818, 825, 832, 839, 847, 1359], '000.': [819], 'rates': [821, 1197], '294.0': [823], '000': [826, 833, 840, 848, 922, 990, 1000, 1013, 1043, 1053, 1061, 1174, 1319, 1344, 1360, 1486, 1493, 1494, 2078, 2084, 2689, 2725], 'white': [828, 842], 'males,': [829, 836], '405.9': [830], 'black': [835, 850], '205.7': [837], 'females,': [843], '286.1': [845], 'females.': [851], '1997': [853, 1097, 2080], '2007,': [855, 884, 936, 1099, 1115, 1674], 'declined': [861, 1113], '27.8%.': [862], 'Mortality': [863, 1065], 'show': [867, 2011], 'that': [868, 1009, 1070, 1154, 1225, 1690, 1706, 1722, 1742, 1758, 2283, 2645, 2804, 2848, 2863], '(I00–I99;': [870], 'Q20–Q28)': [871], 'accounted': [872, 1072], '33.6%': [874], '(813': [875], '804)': [876], '2': [879, 1471, 3952], '243': [880], '712': [881], 'deaths': [882, 890, 940, 969, 1078, 1112], 'or': [885, 1048, 1710, 1752, 2651, 2690, 2696, 2698, 2705, 2711, 2717, 2722, 2726, 2799, 2814, 2818, 2854, 2996, 3009], '1': [886, 914, 1116, 2464, 3336], 'every': [888, 916, 967, 1022, 1034, 1076, 1085, 2793], '2.9': [889], 'United': [893, 972, 1081, 1091, 1126, 1394, 1827, 2138, 2244], 'States.On': [894], 'basis': [896, 1617], 'data,': [901, 1621], '2200': [904], 'Americans': [905, 923, 991, 1240, 1345], 'die': [906, 1038], 'each': [909, 1019], 'day,': [910], 'an': [911, 987, 1010, 1025, 1138, 1170, 1340, 2292, 2557, 2811, 3796], 'average': [912, 956, 1763, 1806], '39': [917], 'seconds.': [918], 'More': [919, 2264], '150': [921], 'killed': [924], 'by': [925, 1461, 1771, 1781, 2298, 2989, 3233, 3350, 3861], '(I00–I99)': [927], '<65': [931], 'years': [932, 1160, 1242, 1303, 1312, 1322, 1422, 1474, 1522, 1654], 'age.': [934, 1672], 'nearly': [937, 1184], '33%': [938], 'due': [941], 'occurred': [944], 'before': [945, 954], 'age': [947, 1162, 1305, 1314, 1324, 1524], '75': [949], 'well': [953, 1898, 1936], 'life': [957], 'expectancy': [958], '77.9': [960], 'years.Coronary': [961], 'caused': [964], '≈1': [965, 1074], '6': [968, 1519, 2082, 4065], 'States': [973, 1092, 1127, 1395, 1828, 2139, 2245], '2007.': [975], 'Coronary': [976, 1993, 3827], '406': [983], '351.': [984], 'Each': [985], 'estimated': [988, 1008, 1171, 1316, 1341, 1412, 2143, 2188], '785': [989], 'will': [992, 1001, 1027, 1037], 'have': [993, 1002, 1028, 1163, 1193, 1227, 1229, 1325, 2261], 'coronary': [996, 1030, 1575, 1955, 3757], 'attack,': [997], '≈470': [999], 'recurrent': [1004, 1049, 1063], 'attack.': [1005], 'It': [1006], 'additional': [1011, 1357, 3005], '195': [1012], 'silent': [1014], 'first': [1015, 1057], 'myocardial': [1016, 3543], 'infarctions': [1017], 'occur': [1018], 'year.': [1020], 'Approximately': [1021, 1051], '25': [1023], 'seconds,': [1024, 1087], 'event,': [1031], 'approximately': [1033], 'minute,': [1035], 'someone': [1036, 1088], 'one.Each': [1040], '≈795': [1042], 'people': [1044], 'experience': [1045], 'stroke.': [1050, 1095, 1974], '610': [1052], 'attacks,': [1058], '185': [1060], 'attacks.': [1064], 'indicate': [1069, 1153, 1757], 'stroke': [1071, 1101, 1111, 2135, 2241, 2969], '18': [1077, 1342], 'States.': [1082], 'average,': [1084], '40': [1086], 'fell': [1104], '44.8%,': [1105], 'actual': [1108, 2650, 2798], 'number': [1109, 2066], '14.7%.In': [1114], '9': [1118, 1264, 1679], 'certificates': [1120], '(277': [1121], '193': [1122], 'deaths)': [1123], 'mentioned': [1128], 'failure.Prevalence': [1130], 'Traditional': [1134], 'Risk': [1135, 3801, 4020], 'Factors': [1136, 4021], 'Issue': [1139, 4135], 'Many': [1141], 'AmericansData': [1142], 'Health': [1146, 2099, 2274, 2497, 2504, 2537, 2552, 3361], 'Nutrition': [1148], 'Examination': [1149], 'Survey': [1150, 2124], '(NHANES)': [1151], '2005–2008': [1152], '33.5%': [1155], 'US': [1157, 1175, 1419, 1440, 1546, 1768], 'adults': [1158, 1176, 1192, 1320, 1420, 1441, 1734, 1769], '≥20': [1159, 1321], 'hypertension': [1164, 1182, 1199, 1228], '(Table': [1165, 1337, 1396, 1468], '7-1).': [1166], 'This': [1167, 2148], 'amounts': [1168], '76': [1172], '400': [1173], 'hypertension.': [1178], 'prevalence': [1180, 1334, 1413, 1514, 1596, 1611, 1624, 3089, 3105], 'equal': [1185], 'between': [1186, 1759], 'men': [1187, 1247, 1645, 1784], 'women.': [1189], 'African': [1190, 1374, 1502], 'among': [1194, 1239, 1644, 1648, 1675, 1767, 3194], 'highest': [1196, 1297], 'world,': [1202], 'at': [1203, 2269, 2384, 2453, 2540, 2787, 2987, 3021, 3064], '44%.': [1204], 'Among': [1205], 'hypertensive': [1206], 'adults,': [1207], '≈80%': [1208], 'aware': [1210, 1224], 'condition,': [1213], '71%': [1214], 'using': [1216, 2120], 'antihypertensive': [1217], 'medication,': [1218], 'only': [1220], '48%': [1221], 'those': [1223, 1299, 1308, 2760], 'they': [1226, 1691], 'condition': [1231], 'controlled.Despite': [1232], '4': [1233, 1300, 4136], 'decades': [1234], 'progress,': [1236], '2008,': [1238, 1339, 2186], '≥18': [1241], 'age,': [1244, 1476], '23.1%': [1245], '18.3%': [1249], 'women': [1251, 1451, 1774], 'continued': [1252], 'be': [1254, 2145, 2267, 2281, 2318, 2647, 2681, 2741, 2850, 2866], 'cigarette': [1255], 'smokers.': [1256], '2009,': [1258], '19.5%': [1259], 'students': [1261], 'grades': [1263, 1678], 'through': [1265, 1680, 2226], '12': [1266, 1309], 'reported': [1267, 1689, 1735, 2658], 'tobacco': [1269], 'use.': [1270], 'percentage': [1272], 'nonsmoking': [1275], 'population': [1276, 1458, 3113], 'detectable': [1278], 'serum': [1279, 1327], 'cotinine': [1280], '(indicating': [1281], 'exposure': [1282, 3352], 'secondhand': [1284], 'smoke)': [1285], '46.4%': [1287], '1999': [1289], '2004,': [1291, 1762], 'declines': [1293], 'occurring,': [1294], '11': [1302, 1521], '(60.5%)': [1306], '19': [1311, 1473], '(55.4%).An': [1315], '33': [1317], '600': [1318], 'total': [1326, 1764, 2065, 2127], 'cholesterol': [1328], 'levels': [1329, 2041, 3337], '≥240': [1330], 'mg/dL,': [1331], '15.0%': [1336], '13-1).In': [1338], '300': [1343, 1427], 'had': [1346, 1361, 1367, 1692], 'diagnosed': [1347], 'diabetes': [1348, 1363, 1390, 1569, 1598], 'mellitus,': [1349, 1364, 1570], 'representing': [1350], '8.0%': [1351], 'adult': [1354, 3987], 'population.': [1355, 1547], 'An': [1356], '7': [1358, 1718], 'undiagnosed': [1362], '36.8%': [1366], 'prediabetes,': [1368], 'abnormal': [1370], 'fasting': [1371], 'glucose': [1372], 'levels.': [1373], 'Americans,': [1375, 1377], 'Mexican': [1376, 1496], 'Hispanic/Latino': [1378], 'individuals,': [1379], 'ethnic': [1382], 'minorities': [1383], 'bear': [1384], 'strikingly': [1386], 'disproportionate': [1387], 'burden': [1388], 'mellitus': [1391, 1599], '16-1).The': [1397], 'Expands': [1400], 'Data': [1401, 1861, 1990, 2031], 'Coverage': [1402], 'Obesity': [1405], 'Epidemic': [1406], 'Its': [1408], 'Antecedents': [1409], 'ConsequencesThe': [1411], 'overweight': [1415, 1465, 1479, 1557, 1613], 'obesity': [1417, 1467, 1516, 1559, 3348], '(≥20': [1421], 'age)': [1424, 1656], '149': [1426], '000,': [1428], 'represents': [1430, 1483, 2638], '67.3%': [1431], 'group': [1434, 2643, 2669, 2834], '2008.': [1436], 'Fully': [1437], '33.7%': [1438], 'obese': [1443, 1481, 1491], '(body': [1444, 1533], 'mass': [1445, 1534], 'index': [1446, 1535], '≥30': [1447, 1536], 'kg/m2).': [1448], 'Men': [1449], 'race/ethnic': [1454], 'groups': [1455], 'affected': [1460], 'epidemic': [1463], '15-1).Among': [1469], 'children': [1470, 1518, 1723], '31.9%': [1477], '(which': [1482], '23': [1484], '500': [1485], 'children),': [1487], '16.3%': [1489], '(12': [1492], 'children).': [1495], 'boys': [1498, 1688], 'girls': [1500, 1504, 1684], 'disproportionately': [1506], 'affected.': [1507], 'Over': [1508], '3': [1511], 'decades,': [1512], 'increased': [1526, 1707, 1770, 1822, 1841, 2073, 3341], '≈4%': [1528], '20%.Obesity': [1532], 'kg/m2)': [1537], 'marked': [1541], 'excess': [1542, 1553], 'Even': [1548], 'notable': [1550], 'terms': [1561], 'factor': [1564, 2040], 'development': [1565], 'incidence': [1567], 'end': [1572], 'points': [1573], 'failure),': [1581], 'numerous': [1583], 'conditions,': [1586], 'including': [1587], 'asthma,': [1588], 'cancer,': [1589], 'degenerative': [1590], 'joint': [1591], 'others.The': [1595], 'increasing': [1601], 'dramatically': [1602], 'time,': [1604], 'parallel': [1606], 'increases': [1609, 1670, 1793], 'obesity.On': [1615], 'NHANES': [1619, 1756, 3088, 3098, 3104, 3124], '2003–2006': [1620], 'age-adjusted': [1623], 'metabolic': [1626], 'syndrome,': [1627], 'cluster': [1629], 'related': [1635, 1820, 1905, 1924, 2113, 2118, 3190], 'overweight/obesity': [1637], 'insulin': [1639], 'resistance,': [1640], '34%': [1642], '(35.1%': [1643], '32.6%': [1647], 'women).The': [1649], 'proportion': [1650, 1669], 'youth': [1652], '(≤18': [1653], 'report': [1658, 2758, 2973], 'engaging': [1659, 1736], 'no': [1661, 1738], 'regular': [1662], 'physical': [1663, 1700], 'activity': [1664, 1705, 1727, 1740], 'high,': [1666], 'adolescents': [1676], '12,': [1681], '29.9%': [1682], '17.0%': [1686], 'not': [1693, 2020, 2766, 3047], 'engaged': [1694], '60': [1696], 'minutes': [1697], 'moderate-to-vigorous': [1699], 'activity,': [1701], 'defined': [1702], 'as': [1703, 1897, 1899, 1935, 1937, 2649, 2657, 2807, 2852, 2868, 3953], 'any': [1704, 2221, 2693, 2797], 'breathing': [1711, 1751], 'rate,': [1712], 'even': [1713], 'once': [1714], 'previous': [1717], 'days,': [1719], 'despite': [1720], 'recommendations': [1721, 2016], 'engage': [1724], 'such': [1726, 2846], '≥5': [1728], 'days': [1729], 'week.Thirty-six': [1731], 'percent': [1732], 'vigorous': [1739], '(activity': [1741], 'causes': [1743], 'heavy': [1744], 'sweating': [1745], 'large': [1748], 'increase': [1749], 'rate).Data': [1754], '1971': [1760], 'energy': [1765], 'consumption': [1766, 1842], '22%': [1772], '(from': [1775, 1785], '1542': [1776], '1886': [1778], 'kcal/d)': [1779], '10%': [1782], '2450': [1786], '2693': [1788], 'kcal/d;': [1789], 'see': [1790], 'Chart': [1791], '19-1).The': [1792], 'calories': [1795, 1837], 'consumed': [1796], 'during': [1797, 2692], 'time': [1799], 'period': [1800], 'attributable': [1802], 'primarily': [1803], 'greater': [1805, 1833], 'carbohydrate': [1807], 'intake,': [1808], 'particular,': [1810, 1941], 'starches,': [1812], 'refined': [1813], 'grains,': [1814], 'sugars.': [1816], 'Other': [1817], 'specific': [1818], 'caloric': [1823], 'intake': [1824], 'include': [1829, 2156], 'larger': [1830], 'portion': [1831], 'sizes,': [1832], 'food': [1834], 'quantity': [1835], 'meal,': [1839], 'sugar-sweetened': [1844], 'beverages,': [1845], 'snacks,': [1846], 'commercially': [1847], 'prepared': [1848], '(especially': [1849], 'fast': [1850], 'food)': [1851], 'meals,': [1852], 'higher': [1854], 'energy-density': [1855], 'foods.The': [1856], 'Provides': [1859], 'Critical': [1860], 'Regarding': [1862], 'Cardiovascular': [1863, 1989, 3198, 3418, 3800, 3836, 3897, 4019, 4052, 4062], 'Quality': [1864], 'Care,': [1866], 'Procedure': [1867, 2044], 'Utilization,': [1868], 'CostsIn': [1870], 'light': [1871], 'utilization,': [1879], 'costs,': [1880, 1896, 2154, 2203, 2209], 'quality,': [1882], 'it': [1883, 2279, 2744], 'critical': [1885, 1912], 'monitor': [1887], 'understand': [1889], 'magnitude': [1891], 'delivery': [1894], 'delivery,': [1904], 'CVDs.': [1907], 'provides': [1910, 2049], 'several': [1915], 'sections.Quality-of-Care': [1916], 'Metrics': [1917], 'CVDsChapter': [1919], '20': [1920], 'reviews': [1921, 2104], 'metrics': [1923, 2022], 'care': [1929, 2026, 3677], 'delivered': [1930], 'patients': [1932, 3681, 3755], 'CVDs,': [1934, 2115], 'disparities.': [1939], '"Get': [1949, 1967, 2000], 'With': [1950, 1968, 2001, 3795, 4058], 'Guidelines"': [1952, 1970, 2003], 'programs': [1953], 'artery': [1956], 'failure': [1960], 'Association/': [1965], 'program': [1971], 'acute': [1973], 'Similar': [1975], 'Veterans': [1979], 'Healthcare': [1980], 'Administration,': [1981], 'Medicare': [1983], 'Medicaid': [1985], 'Registry': [1991, 2004], 'Acute': [1992, 2575, 3826], 'Treatment': [1994, 3686], 'Intervention': [1996], 'Outcomes': [1997], 'Network': [1998], '-': [1999], 'also': [2007, 2033], 'reviewed.': [2008], 'These': [2009], 'impressive': [2012], 'adherence': [2013], 'guideline': [2015], 'many,': [2018], 'but': [2019], 'all,': [2021], 'hospitalized': [2029], 'patients.': [2030], 'reviewed': [2034], 'screening': [2036], 'control.Cardiovascular': [2043], 'Utilization': [2045], 'CostsChapter': [2047], '21': [2048], 'trends': [2052], 'usage': [2055], 'surgical': [2058], 'invasive': [2060], 'procedures.': [2061], 'example,': [2063], 'inpatient': [2068], 'operations': [2070], '27%,': [2074], '5': [2076], '382': [2077], '846': [2083], '(National': [2087], 'Heart,': [2088, 2563], 'Lung,': [2089, 2564], 'Blood': [2091, 2566, 2600], 'Institute': [2092], 'computation': [2093], 'based': [2094, 3108], 'Center': [2097, 2272, 2495], 'data).Chapter': [2102], '22': [2103], 'estimates': [2106, 3090, 3106], 'direct': [2108, 2128, 2202], 'indirect': [2110, 2130, 2208, 2215], 'conditions': [2119], 'Medical': [2121, 2377, 2425, 2446, 2509, 3729], 'Expenditure': [2122], 'Panel': [2123, 3927, 3996], 'data.': [2125], 'cost': [2131, 2158, 2189], '$286': [2146], 'billion.': [2147], 'figure': [2149], 'includes': [2150], 'expenditures': [2152], '(direct': [2153], 'physicians': [2160, 2302], 'hospital': [2164], 'services,': [2165], 'prescribed': [2166], 'medications,': [2167], 'home': [2168], 'durables)': [2174], 'lost': [2176], 'productivity': [2177], 'resulting': [2178], '(indirect': [2181], 'costs).': [2182, 2216], 'By': [2183, 3137], 'comparison,': [2184], 'cancer': [2192], 'benign': [2194], 'neoplasms': [2195], '$228': [2197], 'billion': [2198, 2200, 2205, 2212], '($93': [2199], '$19': [2204], '$116': [2211], 'diagnostic': [2223], 'group.The': [2224], 'continuously': [2230], 'monitors': [2231], 'evaluates': [2233], 'sources': [2234], 'provide': [2247], 'released.': [2263], 'information': [2265], 'can': [2266], 'found': [2268], 'site,': [2277], 'http://www.cdc.gov/nchs/data/nvsr/nvsr58/nvsr58_01.pdf.Finally,': [2278], 'must': [2280], 'noted': [2282], 'product': [2290], 'entire': [2293], 'worth': [2295], 'effort': [2297, 2794], 'dedicated': [2299], 'volunteer': [2301], 'scientists,': [2304], 'outstanding': [2306], 'AHA': [2307, 3016, 3023, 3029], 'staff': [2308], 'members,': [2309], 'without': [2310, 3049], 'whom': [2311], 'publication': [2312, 3203, 3244, 3280, 3309, 3368, 3390, 3439, 3455, 3484, 3510, 3554, 3581, 3667, 3691, 3738, 3776, 3808, 3843, 3870, 3903, 3939, 3971, 4008, 4033], 'would': [2317, 2344], 'impossible.': [2319], 'Their': [2320], 'contributions': [2321], 'gratefully': [2323], 'acknowledged.AcknowledgmentsWe': [2324], 'wish': [2325], 'thank': [2327], 'Thomas': [2328], 'Thom,': [2329], 'Jonathan': [2330], 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