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[388], 'diseases:': [392], 'checklist.': [394], 'JAMA': [395], 'Intern': [396, 440, 574], 'Med.': [397, 441, 575], '2017;177:1020-5.': [398], '28505266]': [400], 'doi:10.1001/jamainternmed.2017.1302': [401], 'Scholar3.': [403], 'Welch': [404], 'HG,': [405], 'Black': [406], 'WC.': [407], 'cancer.': [410], 'Natl': [412], 'Cancer': [413], 'Inst.': [414], '2010;102:605-13.': [415], '20413742]': [417], 'doi:10.1093/jnci/djq099': [418], 'Scholar4.': [420], 'Wiener': [421], 'RS,': [422], 'Schwartz': [423], 'LM,': [424], 'Woloshin': [425], 'S.': [426], 'Time': [427], 'trends': [428], 'pulmonary': [430], 'embolism': [431], 'United': [434], 'States:': [435], 'evidence': [436], 'Arch': [439], '2011;171:831-7.': [442], '21555660]': [444], 'doi:10.1001/archinternmed.2011.178': [445], 'Scholar5.': [447], 'de': [448, 530], 'Lemos': [449], 'JA,': [450], 'Drazner': [451], 'MH,': [452], 'Omland': [453], 'T,': [454], 'Ayers': [455], 'CR,': [456], 'Khera': [457], 'Rohatgi': [459], 'al.': [462], 'Association': [463], 'troponin': [465, 507, 957], 'T': [466, 958], 'detected': [467], 'highly': [470, 544], 'sensitive': [471, 545, 955], 'assay': [472, 959], 'cardiac': [474, 956, 1152], 'structure': [475], 'mortality': [477], 'risk': [478], 'general': [481], 'population.': [482], 'JAMA.': [483], '2010;304:2503-12.': [484], '21139111]': [486], 'doi:10.1001/jama.2010.1768': [487], 'Scholar6.': [489], 'Shah': [490], 'ASV,': [491], 'Anand': [492], 'Strachan': [494], 'FE,': [495], 'Ferry': [496], 'AV,': [497], 'Lee': [498], 'KK,': [499], 'Chapman': [500], 'High-STEACS': [504], 'Investigators.': [505], 'High-sensitivity': [506], 'patients': [512], 'suspected': [514], 'acute': [515], 'coronary': [516], 'syndrome:': [517], 'stepped-wedge,': [519], 'cluster-randomised': [520], 'controlled': [521], 'trial.': [522], 'Lancet.': [523], '2018;392:919-28.': [524], '30170853]': [526], 'doi:10.1016/S0140-6736(18)31923-8': [527], 'Scholar7.': [529], 'Groot': [531], 'JAH,': [532], 'Naaktgeboren': 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