Publication Information

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2972, 3091, 3159, 3210, 3275, 3282, 3352, 3358, 3389, 3538, 3547, 3698, 3705, 3757, 3805, 3896, 3946, 3963, 4022, 4059, 4086, 4206, 4226, 4266, 4271, 4281, 4283, 4308, 4332, 4340, 4375], 'single-stranded': [7, 146], 'closed': [8, 29, 147, 168], 'RNA': [9, 148, 330, 358, 541, 656, 942, 1752, 1786, 1854, 1960, 2012, 2049, 2084, 2370, 2732, 2918, 3152, 3586, 3760, 3808, 3899, 3937, 3974, 4013, 4381], 'molecules': [10, 149], 'that': [11, 150, 284, 384, 1011, 1447, 1468, 1694, 1807, 1876, 1923, 1979, 1996, 2416, 2528, 2880, 3056, 3171, 3679, 3854, 3980, 4079, 4120, 4154, 4173, 4241], 'formed': [13, 152, 1077, 3287], 'by': [14, 153, 329, 486, 1073, 1189, 1707, 1793, 1818, 1882, 1935, 2584, 2886, 3182, 3197, 3545, 3973, 4090], 'precursor': [15, 154, 302], 'mRNA': [16, 155, 303], 'back-splicing': [17, 156, 1161, 3184], 'or': [18, 157, 677, 874, 975, 1465, 1933, 2590, 3725], 'skipping': [19, 158], 'events': [20, 159], 'thousands': [22, 161, 2971], 'genes': [24, 163, 2571, 2954, 4088], 'in': [25, 75, 86, 90, 113, 123, 164, 214, 225, 229, 252, 262, 299, 357, 366, 530, 545, 570, 731, 746, 761, 774, 806, 839, 842, 905, 947, 967, 996, 999, 1038, 1057, 1127, 1235, 1238, 1258, 1345, 1402, 1405, 1427, 1432, 1499, 1513, 1539, 1567, 1603, 1642, 1669, 1721, 1726, 1865, 1902, 1907, 1963, 1985, 1991, 2015, 2052, 2075, 2087, 2117, 2122, 2232, 2512, 2580, 2619, 2624, 2900, 2927, 2955, 2986, 2999, 3060, 3154, 3176, 3195, 3212, 3265, 3277, 3288, 3333, 3356, 3391, 3457, 3486, 3516, 3551, 3591, 3612, 3622, 3653, 3683, 3708, 3722, 3762, 3810, 3833, 3847, 3859, 3862, 3901, 3984, 4102, 4107, 4132, 4143, 4237, 4268, 4278, 4291, 4351], 'eukaryotes': [26, 165], 'as': [27, 64, 95, 132, 166, 203, 234, 271, 337, 579, 674, 752, 803, 1063, 1451, 1698, 1755, 1820, 1858, 1884, 1928, 2366, 2551, 2587, 3701, 3731, 3942, 4018, 4329], 'covalently': [28, 167], 'continuous': [30, 169], 'loops.': [31, 170], 'High-throughput': [32, 171], 'sequencing': [33, 172, 359, 2916], 'and': [34, 50, 60, 67, 78, 89, 97, 107, 127, 135, 173, 189, 199, 206, 217, 228, 236, 246, 266, 274, 293, 308, 326, 361, 369, 374, 456, 465, 490, 501, 532, 542, 572, 596, 622, 682, 685, 691, 726, 756, 813, 884, 945, 1162, 1207, 1209, 1273, 1286, 1296, 1367, 1380, 1430, 1454, 1493, 1502, 1537, 1640, 1675, 1702, 1724, 1824, 1862, 1905, 1939, 1961, 1989, 2013, 2050, 2067, 2085, 2120, 2143, 2170, 2204, 2300, 2434, 2539, 2622, 2647, 2759, 2778, 2780, 2788, 2802, 2866, 2903, 2924, 2930, 2976, 2980, 3001, 3040, 3063, 3112, 3206, 3239, 3268, 3290, 3294, 3313, 3331, 3336, 3354, 3453, 3483, 3522, 3554, 3589, 3616, 3659, 3696, 3720, 3829, 3970, 3988, 4105, 4137, 4146, 4157, 4163, 4168, 4179, 4182, 4231, 4234, 4335, 4353, 4358], 'bioinformatics': [35, 174, 362], 'approaches': [36, 175, 2906], 'have': [37, 176, 364, 382, 589, 1186, 1252, 1445, 1921, 2102, 2302, 2907, 3057, 3676, 4077], 'uncovered': [38, 177, 375], 'the': [39, 104, 124, 178, 243, 263, 334, 367, 385, 548, 551, 764, 790, 822, 855, 978, 1070, 1381, 1433, 1472, 1670, 1727, 1795, 1826, 1890, 1908, 1948, 1992, 1997, 2027, 2034, 2123, 2165, 2192, 2195, 2296, 2429, 2513, 2529, 2561, 2567, 2605, 2625, 2643, 2653, 2701, 2928, 2946, 2987, 3207, 3242, 3273, 3316, 3844, 3985, 3991, 3995, 4108, 4279, 4310, 4341], 'broad': [40, 179], 'expression': [41, 180, 386, 1473, 1483, 1986, 2355, 2702, 2929, 3761, 3809, 3832, 3861, 3900, 4236, 4350], 'circRNAs': [43, 82, 112, 131, 182, 221, 251, 270, 373, 389, 478, 524, 576, 599, 671, 743, 794, 808, 866, 966, 981, 1075, 1081, 1100, 1185, 1212, 1257, 1289, 1386, 1448, 1459, 1469, 1665, 1695, 2100, 2158, 2288, 2576, 2973, 2981, 3172, 3192, 3211, 3276, 3328, 3390, 3479, 3539, 3608, 3680, 3721, 3962, 3979, 4080, 4121, 4267, 4326], 'across': [44, 183, 600], 'species.': [45, 184], 'Their': [46, 185], 'high': [47, 186, 566, 591], 'stability,': [48, 187], 'abundance,': [49, 188], 'evolutionary': [51, 190, 594], 'conservation': [52, 191, 595], 'among': [53, 192], 'species': [54, 193], 'points': [55, 194], 'to': [56, 195, 393, 484, 550, 1179, 1254, 1488, 1496, 2004, 2033, 2161, 2164, 2191, 2353, 2572, 2642, 2774, 2786, 2870, 2911, 3037, 3109, 3201, 3526, 3540, 3561, 3620, 3663, 4165], 'their': [57, 196, 376, 565, 800, 1343, 2357], 'distinct': [58, 197, 3191], 'properties': [59, 198], 'diverse': [61, 200, 1263, 2956], 'cellular': [62, 201, 2035, 4166], 'functions': [63, 202, 725, 2103], 'efficient': [65, 204, 1756], 'microRNAs': [66, 205], 'protein': [68, 207, 1812, 2585, 2588, 2600, 2837, 2865, 2876, 2889], 'sponges;': [69, 208], 'they': [70, 209, 757, 2413, 3076, 3179, 4152], 'also': [71, 116, 210, 255, 820, 2301, 2414, 2526, 2983, 3610, 3852, 4244], 'play': [72, 211], 'important': [73, 212, 377, 4330], 'roles': [74, 213, 310, 503, 693, 727, 792, 1383, 1677, 2172, 3059, 4265], 'modulating': [76, 215, 2106], 'transcription': [77, 216, 2438, 2442, 2511, 2564, 4085], 'splicing.': [79, 218], 'Additionally,': [80, 219, 562, 670, 1080, 2412, 4224], 'most': [81, 220, 1385, 2099], 'aberrantly': [84, 223], 'expressed': [85, 224, 2985, 3485], 'pathological': [87, 226, 1503], 'conditions': [88, 227], 'tissue-specific': [92, 231], 'manner': [93, 232], 'such': [94, 233, 2349, 2424, 2550], 'development': [96, 235, 4334], 'progression': [98, 237], 'cancer.': [100, 239, 807, 2904], 'Herein,': [101, 240, 786], 'we': [102, 115, 241, 254, 787, 4274], 'highlight': [103, 242, 789], 'characteristics,': [105, 244], 'functions,': [106, 245], 'mechanisms': [108, 247, 544, 856], 'action': [110, 249, 858], 'cancer;': [114, 253], 'provide': [117, 256], 'an': [118, 257, 294, 907, 1040, 1129], 'overview': [119, 258], 'recent': [121, 260, 380], 'progress': [122, 261, 838, 995, 1234, 1401], 'circRNA': [125, 264, 345, 817, 860, 1068, 1218, 1808, 2599, 2676, 3260, 3284, 3831, 3845, 3860], 'field': [126, 265], 'future': [128, 267], 'application': [129, 268], 'cancer': [133, 272, 583, 747, 775, 797, 953, 1514, 1542, 1646, 2783, 3359, 3418, 3461, 3520, 3597, 3626, 3657, 4292, 4333], 'biomarkers': [134, 273, 581, 753, 3238, 3312, 3707], 'novel': [136, 275], 'therapeutic': [137, 276, 804], 'targets.': [138, 277], 'endogenous': [282, 679, 1288, 1700], 'can': [285, 867, 1215, 1449, 1460, 1470, 1480, 2031, 2293, 2426, 3523, 3542, 3558, 3660, 3939, 4015], 'form': [286, 1216, 2205], 'between': [287, 463, 2536], 'downstream': [289], '3′': [290, 480, 876], 'splice': [291, 297], 'site': [292, 298, 1106, 1294], 'upstream': [295], '5′': [296, 878], 'linear': [301, 338, 496, 526, 1089, 2199, 3204], '(pre-mRNA)1Chen': [304], 'L.L.': [305, 340, 498, 688, 1156, 1672, 2167, 2326, 2392, 2464], 'The': [306, 499, 689, 723, 1533, 1560, 1596, 1673, 2168, 2592, 3034, 3106, 3350], 'biogenesis': [307, 500, 690, 818, 861, 1674, 2169, 2644, 2677], 'emerging': [309, 502, 692, 724, 908, 1041, 1130, 1676, 2171], 'circular': [312, 419, 457, 505, 655, 695, 729, 840, 997, 1167, 1192, 1236, 1270, 1403, 1679, 2147, 2174, 2508, 2731, 3699, 3759, 3807, 3898, 3936, 4012, 4252, 4380], 'RNAs.Nat.': [313, 506, 696, 1680, 2175], 'Rev.': [314, 507, 697, 1276, 1681, 2176, 4256], 'Mol.': [315, 508, 698, 1606, 1682, 2177, 2516], 'Cell': [316, 509, 699, 1683, 2178], 'Biol.': [317, 347, 510, 700, 1684, 2149, 2179, 2517], '2016;': [318, 469, 511, 701, 1170, 1278, 1685, 2180, 2844, 3006, 3162, 3423, 3529, 3666, 4066, 4213, 4258], '17:': [319, 512, 702, 1279, 1686, 2181], '205-211Crossref': [320, 513, 703, 1687, 2182], 'PubMed': [321, 351, 431, 472, 514, 557, 630, 665, 704, 737, 781, 849, 916, 959, 1006, 1049, 1138, 1173, 1245, 1281, 1331, 1375, 1412, 1438, 1520, 1549, 1579, 1611, 1659, 1688, 1732, 1762, 1801, 1872, 1913, 1969, 2021, 2058, 2093, 2128, 2153, 2183, 2241, 2280, 2341, 2407, 2479, 2521, 2630, 2691, 2741, 2766, 2809, 2847, 2963, 3009, 3051, 3083, 3123, 3165, 3249, 3323, 3366, 3400, 3426, 3474, 3532, 3603, 3669, 3715, 3774, 3822, 3913, 3954, 4030, 4074, 4113, 4221, 4298, 4321, 4390], 'Scopus': [322, 352, 432, 473, 515, 558, 631, 666, 705, 738, 782, 850, 917, 960, 1007, 1050, 1139, 1174, 1246, 1282, 1332, 1376, 1413, 1439, 1521, 1550, 1580, 1612, 1660, 1689, 1733, 1763, 1802, 1914, 1970, 2022, 2059, 2094, 2129, 2154, 2184, 2281, 2342, 2408, 2480, 2522, 2631, 2692, 2742, 2767, 2810, 2848, 2964, 3010, 3052, 3084, 3124, 3166, 3250, 3324, 3367, 3401, 3427, 3475, 3533, 3604, 3670, 3716, 3775, 3823, 3914, 3955, 4031, 4114, 4299, 4322], '(1005)': [323, 516, 706, 1690, 2185], 'Google': [324, 354, 434, 475, 517, 560, 633, 668, 707, 740, 784, 852, 919, 962, 1009, 1052, 1141, 1176, 1248, 1284, 1334, 1378, 1415, 1441, 1523, 1552, 1582, 1614, 1662, 1691, 1735, 1765, 1804, 1873, 1916, 1972, 2024, 2061, 2096, 2131, 2156, 2186, 2242, 2283, 2344, 2410, 2482, 2524, 2633, 2694, 2744, 2769, 2812, 2850, 2966, 3012, 3054, 3086, 3126, 3168, 3252, 3326, 3369, 3403, 3429, 3477, 3535, 3606, 3672, 3718, 3777, 3825, 3916, 3957, 4033, 4075, 4116, 4222, 4301, 4324], 'Scholar': [325, 355, 476, 518, 561, 669, 741, 785, 853, 963, 1010, 1053, 1177, 1249, 1285, 1335, 1379, 1442, 1663, 1692, 1766, 1805, 1874, 1917, 1973, 2025, 2062, 2097, 2157, 2187, 2284, 2345, 2411, 2483, 2525, 2634, 2695, 2770, 2813, 2851, 2967, 3013, 3055, 3087, 3127, 3169, 3253, 3327, 3478, 3536, 3607, 3673, 3719, 3778, 3826, 3917, 3958, 4034, 4076, 4117, 4223, 4261, 4325], 'transcribed': [328], 'polymerase': [331, 2371], 'II': [332, 2372, 2432, 2563], 'with': [333, 459, 624, 749, 1262, 1369, 2274, 2287, 2295, 2428, 2560, 2679, 2873, 2974, 3186, 3219, 3292, 3449, 3489, 3843, 3866, 3870, 3965], 'same': [335], 'efficiency': [336], 'RNAs.2Chen': [339], 'Yang': [341, 410, 446, 639, 645, 647, 713, 829, 986, 1157, 1225, 1392, 2323, 2389, 2461, 2715, 2721, 2723, 2750, 2756, 2793, 2799, 4364, 4370, 4372], 'L.': [342, 638, 1158, 1266, 1309, 1772, 2257, 2324, 2390, 2462, 2493, 2505, 2714, 3147, 3931, 4007, 4363], 'Regulation': [343], 'biogenesis.RNA': [346], '2015;': [348, 956, 1798, 2518, 3080, 3600, 3712], '12:': [349, 3467], '381-388Crossref': [350], '(1108)': [353], 'Advances': [356], '(RNA-seq)': [360], 'tools': [363], 'resulted': [365], 'discovery': [368], 'identification': [370, 450, 2142], 'various': [372, 2901, 4269], 'roles.': [378], 'First,': [379], 'reports': [381], 'indicated': [383, 590, 1806, 1922, 1978], 'certain': [388], 'is': [390, 528, 943, 1061, 1338, 2189, 2602, 2650, 3156, 3215, 3447, 3587, 3841, 3856, 4345], 'highly': [391], 'specific': [392, 2875, 2881], 'cell': [394, 1264, 1880, 2784, 2957, 3188, 4161, 4248], 'type': [395], 'and/or': [396], 'developmental': [397, 2977], 'stage.3Panda': [398], 'A.C.': [399], 'Grammatikakis': [400], 'I.': [401], 'Kim': [402, 1618, 1622, 3435], 'K.M.': [403], 'De': [404], 'S.': [405, 710, 828, 928, 940, 985, 1224, 1391, 1631, 2245, 2322, 2388, 2460, 2671, 2675, 2821, 2823, 2829, 2997, 3378, 3384, 3440, 3505, 3572, 3584, 3642, 3688], 'Martindale': [406], 'J.L.': [407, 1150, 3495, 3632], 'Munk': [408], 'R.': [409, 720, 1146, 1305, 2657, 3230, 3304], 'X.': [411, 714, 938, 2497, 3412, 3582, 3746, 3750, 3794, 3798, 3885, 3889, 3923, 3999], 'Abdelmohsen': [412], 'K.': [413, 606, 1351, 4046, 4193], 'Gorospe': [414], 'M.': [415, 1303, 1311, 1780, 2226, 2247, 2263, 2495, 2659, 2667, 3025, 3097, 3141, 3236, 3310, 3380, 3738, 3786, 3877, 3933, 4009, 4040, 4187], 'Identification': [416, 3695], 'senescence-associated': [418], '(SAC-RNAs)': [421], 'reveals': [422], 'senescence': [423], 'suppressor': [424], 'CircPVT1.Nucleic': [425], 'Acids': [426, 467], 'Res.': [427, 468, 955, 1169, 1965, 2017, 2054, 2089, 2237, 3245, 3319, 3599], '2017;': [428, 662, 846, 913, 1003, 1046, 1135, 1242, 1323, 1409, 1546, 1571, 1869, 2738, 2763, 2806, 3246, 3320, 3363, 3951, 4027, 4387], '45:': [429], '4021-4035Crossref': [430], '(153)': [433], 'Scholar,': [435, 634, 708, 920, 1142, 1416, 1524, 1553, 1583, 1615, 1736, 2132, 2243, 2745, 3370, 3404, 3430, 4302], '4Chuang': [436], 'T.J.': [437], 'Wu': [438, 641, 2717, 4366], 'C.S.': [439], 'Chen': [440, 933, 1155, 1830, 1842, 2313, 2325, 2379, 2391, 2451, 2463, 2492, 3577], 'C.Y.': [441], 'Hung': [442, 2818, 3373], 'L.Y.': [443], 'Chiang': [444], 'T.W.': [445], 'M.Y.': [447], 'NCLscan:': [448], 'accurate': [449], 'non-co-linear': [452], 'transcripts': [453, 3285], '(fusion,': [454], 'trans-splicing': [455], 'RNA)': [458], 'good': [461], 'balance': [462], 'sensitivity': [464, 2785], 'precision.Nucleic': [466], '44:': [470], 'e29Crossref': [471], '(67)': [474], 'Second,': [477], 'lacking': [479], 'termini': [481], 'resistant': [483], 'degradation': [485], 'exonuclease': [487], 'RNase': [488, 3199], 'R': [489, 3200], 'more': [492, 3481], 'stable': [493, 946, 1217, 3590], 'than': [494, 525, 2105], 'associated': [495, 623, 1368, 3448, 3548], 'mRNAs;1Chen': [497], 'therefore,': [519], 'higher': [521], 'concentration': [522], 'mRNAs': [527, 1492], 'present': [529], 'quiescent': [531], 'post-mitotic': [533], 'cells.5Han': [534], 'B.': [535, 898, 1031, 1120, 1746, 1843, 1847, 2220, 2224, 2501, 3511, 3648], 'Chao': [536], 'J.': [537, 612, 716, 896, 932, 936, 1029, 1118, 1154, 1268, 1357, 1424, 1544, 1605, 1718, 1750, 1776, 1778, 1782, 1833, 1841, 1899, 1956, 2008, 2045, 2080, 2114, 2253, 2616, 2831, 2934, 3005, 3361, 3576, 3580, 3740, 3748, 3788, 3796, 3879, 3887, 4038, 4099, 4185], 'Yao': [538], 'H.': [539, 718, 722, 2138, 2825, 3406, 3408, 3736, 3784, 3875], 'its': [543, 2444, 2704], 'disease:': [546], 'from': [547, 795, 811, 869, 875, 973, 1085, 2289, 2604, 2919, 2950, 3023, 3339, 3864, 4062, 4084, 4123, 4209, 4254], 'bench': [549], 'clinic.Pharmacol.': [552], 'Ther.': [553, 1569, 1648, 3463], '2018;': [554, 734, 778, 1435, 1517, 1608, 1651, 1729, 1910, 2125, 2627, 3043, 3115, 3397, 3466, 3766, 3814, 3905, 4110, 4295], '187:': [555], '31-44Crossref': [556], '(419)': [559], 'because': [563], 'level': [567, 1827], 'stability': [569], 'blood': [571, 3020, 3723, 3727, 3758, 3806, 3836, 3897, 3935, 3961, 4011], 'other': [573, 1182, 2104, 2581], 'body': [574], 'fluids,': [575], 'considered': [578, 1062], 'potential': [580, 751, 2362], 'for': [582, 754, 952, 1013, 1342, 1709, 1887, 2305, 2364, 2922, 3596, 4247], 'risk': [584], 'prediction.': [585], 'Third,': [586], 'genome-wide': [587], 'analyses': [588, 1251], 'levels': [592, 1941, 2639, 3550], 'abundance': [597], 'species.6Jeck': [601], 'W.R.': [602, 1347], 'Sorrentino': [603, 1348], 'J.A.': [604, 1349], 'Wang': [605, 895, 1028, 1117, 1350, 2496, 2937], 'Slevin': [607, 1352], 'M.K.': [608, 1353], 'Burd': [609, 1354], 'C.E.': [610, 1355], 'Liu': [611, 711, 1356, 3735, 3783, 3874], 'Marzluff': [613, 1358], 'W.F.': [614, 1359], 'Sharpless': [615, 1360], 'N.E.': [616, 1361], 'abundant,': [620, 1365], 'conserved,': [621, 1366], 'ALU': [625, 1370], 'repeats.RNA.': [626, 1371], '2013;': [627, 1372, 1759, 1966, 2018, 2055, 2090, 2277, 2333, 2399, 2471], '19:': [628, 1373, 1609], '141-157Crossref': [629, 1374], '(2610)': [632, 1377], '7Du': [635], 'W.W.': [636, 2712, 2747, 2790, 4361], 'Fang': [637, 2713, 4362], 'W.': [640, 892, 894, 930, 1025, 1027, 1114, 1116, 1774, 2503, 2716, 2751, 2794, 3410, 3574, 4365], 'N.': [642, 830, 987, 1226, 1393, 1629, 2669, 2673, 2718, 2940, 3222, 3296, 3503, 3640, 3694, 3742, 3790, 3881, 4367], 'Awan': [643, 2719, 2754, 2797, 4368], 'F.M.': [644, 2720, 2755, 2798, 4369], 'Z.': [646, 712, 890, 1023, 1112, 1152, 1851, 2487, 2722, 3734, 3782, 3873, 3921, 3997, 4371], 'B.B.': [648, 2724, 2757, 2800, 4373], 'Induction': [649, 2725, 4374], 'tumor': [651, 1816, 2727, 2868, 4272, 4376], 'apoptosis': [652, 2728, 4230, 4377], 'through': [653, 1101, 2554, 2707, 2729, 4378], 'enhancing': [657, 2733, 4382], 'Foxo3': [658, 2734, 4383], 'activity.Cell': [659, 2735, 4384], 'Death': [660, 2736, 4385], 'Differ.': [661, 2737, 4386], '24:': [663, 2239, 2739, 4388], '357-370Crossref': [664, 2740, 4389], '(378)': [667, 2743], 'might': [672, 1878, 2351, 2547, 2699, 3728, 4354], 'act': [673, 1697, 1927], 'miRNA': [675, 1452, 1705, 1822, 1952, 2068, 3549], 'sponges': [676, 1453], 'competing': [678, 1708], 'RNA,': [680, 2425], 'bind': [681, 2775], 'sequester': [683], 'proteins,': [684, 1466], 'modulate': [686, 1471, 1481, 2700], 'splicing.1Chen': [687], '8Qu': [709], 'Zhou': [715, 1783], 'Yu': [717, 2500], 'Zhang': [719, 899, 1032, 1121, 1147, 1149, 1153, 1771, 2311, 2377, 2449, 2748, 2791, 3411, 3510, 3647, 3743, 3745, 3791, 3793, 3882, 3884], 'Li': [721, 827, 897, 927, 984, 1030, 1119, 1223, 1390, 1767, 1773, 1834, 2484, 3571, 3737, 3741, 3785, 3789, 3876, 3880, 3922, 3932, 3998, 4008], 'cancer.Cancer': [732, 1867, 1964, 2016, 2053, 2088], 'Lett.': [733, 777, 845, 1002, 1241, 1408, 1516, 1868, 4294], '414:': [735], '301-309Crossref': [736], '(181)': [739], 'Thus,': [742], 'significant': [745, 4246], 'pathogenesis': [748], 'great': [750], 'cancer,': [755, 2697], 'likely': [759], 'involved': [760, 1498, 2579], 'many': [762], 'hallmarks': [765, 4282], 'cancer.9Bach': [767, 1506, 4284], 'D.-H.': [768, 1507, 1526, 1555, 3343, 3432, 4285], 'Lee': [769, 1508, 1531, 1558, 1594, 1626, 3348, 3443, 4286], 'S.K.': [770, 1509, 1532, 1559, 1595, 3349, 3444, 4287], 'Long': [771, 1510, 1586, 1850, 4288], 'noncoding': [772, 1511, 2330, 2396, 2468, 4289], 'cells.Cancer': [776, 1515, 4293], '419:': [779, 1518, 4296], '152-166Crossref': [780, 1519, 4297], '(117)': [783, 1522, 4300], 'will': [788], 'critical': [791, 3058], 'perspective,': [798], 'including': [799, 1505, 4127], 'possible': [801, 4264], 'role': [802, 1534, 1562, 1598, 2363, 3351, 4058, 4205], 'targets': [805], 'derived': [810, 972, 2603, 3022, 3338, 4061, 4083, 4122, 4208], 'pre-mRNAs,': [812], 'thus': [814, 3555], 'modulation': [815, 2064, 2636], 'may': [819, 1082, 1095, 1696, 1926, 2071, 2577, 3279, 4081, 4159, 4243, 4327], 'require': [821, 3280], 'canonical': [823, 1086], 'spliceosomal': [824], 'machinery.10Huang': [825], 'G.': [826, 983, 1222, 1389, 2499, 2995], 'Zou': [831, 988, 1227, 1394], 'Y.': [832, 886, 922, 989, 1019, 1108, 1148, 1228, 1395, 1633, 1784, 1835, 1849, 2310, 2376, 2448, 3491, 3566, 3628, 3744, 3752, 3792, 3800, 3883, 3891, 4052, 4199], 'Zheng': [833, 923, 990, 1229, 1396, 1777, 1836, 1846, 3567], 'D.': [834, 888, 934, 991, 1021, 1110, 1230, 1315, 1397, 1619, 1845, 3436, 3578, 3927, 4003, 4304], 'Xiao': [835, 992, 1231, 1398], 'T.': [836, 993, 1232, 1399, 2222, 2314, 2380, 2452, 2753, 2796, 2817, 3226, 3300, 3376], 'Recent': [837, 994, 1233, 1400, 1443, 3674], 'human': [843, 968, 1000, 1239, 1406, 2953, 3684, 3709, 3834, 3848], 'cancers.Cancer': [844, 1001, 1240, 1407], '404:': [847, 1004, 1243, 1410], '8-18Crossref': [848, 1005, 1244, 1411], '(82)': [851, 1008, 1247, 1414, 3085], 'However,': [854, 1336, 2098, 3254], 'not': [863], 'fully': [864], 'understood.': [865], 'originate': [868], 'exons': [870], 'coding': [872], 'regions': [873], 'UTR,': [877, 879], 'antisense': [880], 'RNAs,': [881], 'intergenic': [882], 'regions,': [883], 'introns.11Dong': [885], 'He': [887, 937, 1020, 1109, 1840, 3581], 'Peng': [889, 891, 1022, 1024, 1111, 1113], 'Shi': [893, 1026, 1115, 3739, 3787, 3878], 'C.': [900, 902, 926, 1033, 1035, 1122, 1124, 1307, 1839, 2489, 2491, 2749, 2792, 2936, 3143, 3372, 3570, 3925, 4001], 'Duan': [901, 1034, 1123], 'cancer:': [906, 1039, 1128, 1428, 1722, 1903, 2118, 2620, 3038, 3110, 4103, 4309], 'key': [909, 1042, 1131], 'player.J.': [910, 1043, 1132], 'Hematol.': [911, 1044, 1133], 'Oncol.': [912, 1045, 1134], '10:': [914, 1047, 1136, 3713], '2Crossref': [915, 1048, 1137], '(189)': [918, 1051, 1140], '12Li': [921], 'Q.': [924, 1837, 2216, 3568], 'Bao': [925, 1838, 2490, 3569], 'Guo': [929, 2137, 3573], 'Zhao': [931, 3575, 3918], 'Gu': [935, 3579], 'Huang': [939, 2488, 3583], 'enriched': [944, 3175, 3588, 3682], 'exosomes:': [948, 3592], 'promising': [950, 3417, 3594], 'biomarker': [951, 3595, 3945, 4021], 'diagnosis.Cell': [954, 3598], '25:': [957, 3601], '981-984Crossref': [958, 3602], '(1340)': [961, 3605], 'Among': [964], 'them,': [965], 'cells': [969, 3021, 3521, 3563, 3658, 3838], 'mainly': [971], 'single': [974, 1092], 'several': [976, 1259], 'exons,': [977, 2291], 'so-called': [979], 'exonic': [980], '(ecircRNAs)10Huang': [982], 'account': [1012], 'over': [1014], '80%': [1015], 'identified': [1017, 1188, 2527, 2970, 3194, 3977], 'circRNAs.11Dong': [1018], 'Although': [1054], 'alternative': [1055, 1102, 1160, 1163], 'splicing,': [1056], 'particular': [1058], 'exon': [1059, 3183], 'skipping,': [1060], 'major': [1065], 'modulator': [1066], 'production,': [1069], 'main': [1071], 'mechanism': [1072], 'which': [1074, 1196, 1203, 1214, 1925, 2188, 2440, 2546, 3840, 4347], 'remains': [1078], 'elusive.': [1079], 'be': [1083, 1461, 1497, 2072, 2162, 2578, 3524, 3543, 3559, 3618, 3661, 3729, 3940, 4016, 4082, 4245], 'different': [1084], 'splicing': [1087, 1164, 3093], 'RNAs;': [1090], 'gene': [1093, 1103, 1475, 1482, 2446, 2574], 'locus': [1094, 1104], 'produce': [1096], 'variety': [1098], 'back-splice': [1105], 'selection.11Dong': [1107], '13Zhang': [1143], 'X.O.': [1144, 2312, 2378, 2450], 'Dong': [1145], 'Luo': [1151], 'Diverse': [1159], 'landscape': [1165], 'RNAs.Genome': [1168, 2148], '26:': [1171], '1277-1287Crossref': [1172], '(472)': [1175], 'Up': [1178], 'now,': [1180], 'three': [1181], 'types': [1183], 'been': [1187, 2908], 'high-throughput': [1190], 'sequencing:': [1191], 'intronic': [1193, 1211, 2328, 2394, 2466], '(ciRNAs),': [1195], 'contain': [1197, 1204, 1290], 'introns': [1198, 1206], 'only;': [1199], 'exon-intron': [1200], 'cirRNAs': [1201], '(EIciRNAs),': [1202], 'both': [1205, 2776], 'exons;': [1208], 'tRNA': [1210], '(tricRNAs),': [1213], 'via': [1219, 1484], 'pre-tRNA': [1220], 'splicing.10Huang': [1221], 'RNA-seq': [1250, 2905, 2968], 'helped': [1253], 'identify': [1255], 'numerous': [1256], 'model': [1260], 'organisms': [1261], 'types,14Szabo': [1265], 'Salzman': [1267], 'Detecting': [1269], 'RNAs:': [1271, 3415], 'bioinformatic': [1272], 'experimental': [1274, 4343], 'challenges.Nat.': [1275], 'Genet.': [1277], '679-692Crossref': [1280], '(392)': [1283], 'some': [1287, 1919], 'internal': [1291], 'ribosome': [1292], 'entry': [1293], 'elements': [1295], 'AUG': [1297], 'sites.15Pamudurti': [1298], 'N.R.': [1299, 2661], 'Bartok': [1300, 2664], 'O.': [1301, 2665, 2827, 3066, 3692], 'Jens': [1302, 2246], 'Ashwal-Fluss': [1304], 'Stottmeister': [1306], 'Ruhe': [1308], 'Hanan': [1310, 2666], 'Wyler': [1312], 'E.': [1313, 1317, 2992], 'Perez-Hernandez': [1314], 'Ramberger': [1316], 'et': [1318, 1636, 1768, 1831, 1852, 2264, 2485, 2506, 2815, 3129, 3150, 3753, 3780, 3801, 3892, 3919, 4036], 'al.Translation': [1319], 'CircRNAs.Mol.': [1321], 'Cell.': [1322, 2332, 2398, 2470, 2682, 3042, 3114], '66:': [1324], '9-21.e7Abstract': [1325], 'Full': [1326, 1328, 1574, 1576, 1654, 1656, 2336, 2338, 2402, 2404, 2474, 2476, 2686, 2688, 3046, 3048, 3118, 3120, 3469, 3471, 3769, 3771, 3817, 3819, 3908, 3910, 4069, 4071, 4216, 4218, 4316, 4318], 'Text': [1327, 1329, 1575, 1577, 1655, 1657, 2337, 2339, 2403, 2405, 2475, 2477, 2687, 2689, 3047, 3049, 3119, 3121, 3470, 3472, 3770, 3772, 3818, 3820, 3909, 3911, 4070, 4072, 4217, 4219, 4317, 4319], 'PDF': [1330, 1578, 1658, 2340, 2406, 2478, 2690, 3050, 3122, 3473, 3773, 3821, 3912, 4073, 4220, 4320], '(987)': [1333], 'there': [1337, 1980, 3255, 3855], 'currently': [1339], 'limited': [1340, 3257], 'evidence': [1341, 3678], 'translation': [1344], 'vivo,6Jeck': [1346], 'biological': [1382, 1501, 2920, 3556], 'remain': [1387], 'unknown.10Huang': [1388], '16Kristensen': [1417], 'L.S.': [1418, 1712, 1893, 2108, 2610, 4093], 'Hansen': [1419, 1713, 1894, 2109, 2611, 4094], 'T.B.': [1420, 1714, 1738, 1895, 1954, 2006, 2043, 2078, 2110, 2612, 4095], 'Venø': [1421, 1715, 1896, 2111, 2613, 4096], 'M.T.': [1422, 1716, 1897, 2112, 2614, 4097], 'Kjems': [1423, 1717, 1749, 1898, 1955, 2007, 2044, 2079, 2113, 2615, 4098], 'opportunities': [1429, 1723, 1904, 2119, 2621, 4104], 'challenges': [1431, 1725, 1906, 2121, 2623, 3039, 3111, 4106], 'field.Oncogene.': [1434, 1728, 1909, 2124, 2626, 4109], '37:': [1436, 1730, 1911, 2126, 2628, 4111], '555-565Crossref': [1437, 1731, 1912, 2127, 2629, 4112], '(827)': [1440, 1734, 1915, 2130, 2632, 4115], 'studies': [1444, 1920, 1977, 2894, 3258, 3675], 'shown': [1446, 4078], 'function': [1450, 1754], 'modulators': [1455, 1703, 2368], 'transcription;': [1457], 'few': [1458], 'translated': [1462], 'into': [1463, 3094, 3272], 'peptides': [1464], 'implying': [1467], 'at': [1476, 2437, 2566], 'multiple': [1477, 1500, 4124], 'levels.': [1478], 'miRNAs': [1479, 1538, 2066, 3293, 3355], 'direct': [1485], 'base': [1486], 'pairing': [1487], 'target': [1489, 2306], 'sites': [1490, 2307], 'within': [1491], 'known': [1495, 2867], 'processes,': [1504], '17Bach': [1525], 'Hong': [1527, 1624, 3344], 'J.-Y.': [1528, 3345], 'Park': [1529, 1556, 3346, 3439, 3441], 'H.J.': [1530, 1557, 1627, 3347, 3442], 'exosomes': [1536, 3353, 3487, 3541, 3621], 'drug-resistance': [1540, 3357], 'cells.Int.': [1543, 3360], 'Cancer.': [1545, 3362, 4257], '141:': [1547, 3364], '220-230Crossref': [1548, 3365], '(163)': [1551, 3368], '18Bach': [1554], 'dual': [1561], 'bone': [1564], 'morphogenetic': [1565], 'proteins': [1566, 1602, 2706], 'cancer.Mol.': [1568], 'Oncolytics.': [1570], '8:': [1572], '1-13Abstract': [1573], '(89)': [1581], '19Bach': [1584], 'D.H.': [1585, 1617], 'N.P.': [1587], 'Luu': [1588, 1634, 3433], 'T.T.': [1589, 1635], 'Anh': [1590], 'N.H.': [1591], 'Kwon': [1592, 1630], 'S.W.': [1593], 'dominant': [1597], 'forkhead': [1600], 'box': [1601], 'cancer.Int.': [1604], 'Sci.': [1607], 'E3279Crossref': [1610], '(1)': [1613], '20Bach': [1616], 'Bae': [1620], 'S.Y.': [1621], 'W.K.': [1623], 'J.Y.': [1625], 'Rajasekaran': [1628], 'Fan': [1632], 'al.Targeting': [1637], 'Nicotinamide': [1638], 'N-Methyltransferase': [1639], 'miR-449a': [1641], 'EGFR-TKI-resistant': [1643], 'non-small-cell': [1644, 3459], 'lung': [1645, 3460], 'cells.Mol.': [1647, 3462], 'Nucleic': [1649, 3464], 'Acids.': [1650, 3465], '11:': [1652], '455-467Abstract': [1653], '(45)': [1661], 'Most': [1664], 'predominantly': [1667], 'located': [1668], 'cytoplasm,1Chen': [1671], 'suggesting': [1693, 1995, 4172, 4240], 'competitive': [1699], 'activity': [1706, 1938, 2069, 3557], 'miRNA-binding': [1710], 'sites.16Kristensen': [1711], '21Hansen': [1737], 'Jensen': [1739], 'T.I.': [1740], 'Clausen': [1741], 'B.H.': [1742], 'Bramsen': [1743], 'J.B.': [1744], 'Finsen': [1745], 'Damgaard': [1747, 1957, 2009, 2046, 2081], 'C.K.': [1748, 1958, 2010, 2047, 2082], 'Natural': [1751], 'circles': [1753], 'microRNA': [1757], 'sponges.Nature.': [1758], '495:': [1760, 2278], '384-388Crossref': [1761], '(4720)': [1764], 'al.22Li': [1769], 'F.': [1770, 2251, 3068, 4050, 4197], 'Deng': [1775], 'An': [1779, 3437], 'Lu': [1781, 3229, 3303], 'ITCH': [1787], 'has': [1788, 1945, 2969, 4348], 'inhibitory': [1789], 'effect': [1790, 2649], 'on': [1791, 2652, 2853, 3259], 'ESCC': [1792], 'suppressing': [1794], 'Wnt/β-catenin': [1796], 'pathway.Oncotarget.': [1797], '6:': [1799, 2845, 3007, 3081, 3530, 3667], '6001-6013Crossref': [1800], '(561)': [1803], 'itchy': [1809], 'E3': [1810], 'ubiquitin': [1811], 'ligase': [1813], '(cir-ITCH)': [1814], 'suppressed': [1815], 'growth': [1817, 1881], 'acting': [1819], 'sponge': [1823, 1886, 1934, 2601], 'increased': [1825, 3983, 4232], 'ITCH.': [1829], 'al.23Chen': [1832], 'Lyu': [1844], 'Xu': [1848, 3409], 'al.Circular': [1853, 2265, 3151], 'profile': [1855], 'identifies': [1856], 'circPVT1': [1857, 1877], 'proliferative': [1860, 4337], 'factor': [1861], 'prognostic': [1863], 'marker': [1864], 'gastric': [1866], '388:': [1870], '208-219Crossref': [1871], 'reported': [1875], 'stimulate': [1879, 2573], 'playing': [1883], 'members': [1888], 'miR-125': [1891], 'family.16Kristensen': [1892], 'Importantly,': [1918, 2635, 4151], 'ciRS-7,': [1924], 'designated': [1930], 'miR-7': [1931, 1937, 1962, 1990, 2001, 2014, 2051, 2086], 'inhibitor': [1932], 'reducing': [1936], 'increasing': [1940], 'miR-7-targeted': [1943], 'transcripts,': [1944, 3205], 'conceptually': [1946], 'changed': [1947], 'mechanistic': [1949], 'understanding': [1950], 'networks.24Hansen': [1953], '73:': [1967, 2019, 2056, 2091], '5609-5612Crossref': [1968, 2020, 2057, 2092], '(725)': [1971, 2023, 2060, 2095], 'In': [1974, 2285, 2696], 'situ': [1975], 'profiling': [1976], 'was': [1981, 2002, 2772], 'remarkable': [1983], 'overlap': [1984], 'ciRS-7': [1988], 'mouse': [1993], 'brain,': [1994], 'majority': [1998], 'brain-expressed': [2000], 'tethered': [2003], 'ciRS-7.24Hansen': [2005], 'Hence,': [2026], 'abundant': [2028, 2423, 3482, 3830], 'ciRS-7/miR-7': [2029], 'correlation': [2030], 'contribute': [2032, 4164], 'pool': [2036], 'available': [2038], 'RNA-induced': [2039], 'silencing': [2040], 'complex': [2041, 2433, 2565], 'components.24Hansen': [2042], 'Consequently,': [2063], 'generally': [2070], 'less': [2073], 'pronounced': [2074], 'ciRS-7/miR-7-expressing': [2076], 'tissues.24Hansen': [2077], 'could': [2101, 2557, 3617], 'miRNAs.16Kristensen': [2107], '25Guo': [2133], 'J.U.': [2134], 'Agarwal': [2135], 'V.': [2136, 3031, 3103], 'Bartel': [2139], 'D.P.': [2140], 'Expanded': [2141], 'characterization': [2144, 3697], 'mammalian': [2146], '2014;': [2150, 2238, 2683], '15:': [2151], '409Crossref': [2152], '(1057)': [2155], 'suggested': [2160, 2879], 'restricted': [2163], 'nucleus,1Chen': [2166], 'similar': [2190], 'observation': [2193], 'nuclear': [2196, 2297, 2532], 'restriction': [2197], 'containing': [2201], 'retained': [2202], 'introns,': [2203], 'large': [2207, 2269], 'number': [2208], 'post-transcriptional': [2210], 'modulators.26Braunschweig': [2211], 'U.': [2212], 'Barbosa-Morais': [2213], 'N.L.': [2214], 'Pan': [2215], 'Nachman': [2217], 'E.N.': [2218], 'Alipanahi': [2219], 'Gonatopoulos-Pournatzis': [2221], 'Frey': [2223], 'Irimia': [2225], 'Blencowe': [2227], 'B.J.': [2228], 'Widespread': [2229], 'intron': [2230], 'retention': [2231], 'mammals': [2233], 'functionally': [2234], 'tunes': [2235], 'transcriptomes.Genome': [2236], '1774-1786Crossref': [2240], '27Memczak': [2244], 'Elefsinioti': [2248], 'A.': [2249, 2255, 2663, 2833, 2990, 3139, 3232, 3306, 3382, 3386], 'Torti': [2250], 'Krueger': [2252], 'Rybak': [2254], 'Maier': [2256], 'Mackowiak': [2258], 'S.D.': [2259], 'Gregersen': [2260], 'L.H.': [2261, 2819], 'Munschauer': [2262], 'animal': [2272], 'regulatory': [2275], 'potency.Nature.': [2276], '333-338Crossref': [2279], '(4733)': [2282], 'contrast': [2286], 'back-spliced': [2290], 'ciRNAs': [2292, 2365], 'associate': [2294], 'insoluble': [2298], 'fraction': [2299], 'little': [2303], 'enrichment': [2304, 3153], 'miRNAs.28Zhang': [2309], 'Xiang': [2315, 2381, 2453], 'J.F.': [2316, 2382, 2454], 'Yin': [2317, 2383, 2455], 'Q.F.': [2318, 2384, 2456], 'Xing': [2319, 2385, 2457], 'Y.H.': [2320, 2386, 2458], 'Zhu': [2321, 2387, 2459], 'long': [2329, 2395, 2467], 'RNAs.Mol.': [2331, 2397, 2469], '51:': [2334, 2400, 2472], '792-806Abstract': [2335, 2401, 2473], '(1422)': [2343, 2409, 2481], 'Significantly,': [2346], 'knockdown': [2347, 4225], 'lead': [2352], 'reduced': [2354], 'parent': [2358], 'genes,': [2359], 'eliciting': [2360], 'one': [2361, 2422], 'positive': [2367], '(Pol': [2373], 'II)': [2374], 'transcription.28Zhang': [2375], 'found': [2415, 2773, 3170, 3853, 4119, 4153], 'ci-Ankyrin': [2417], 'Repeat': [2418], 'Domain': [2419], '52': [2420], '(ci-ANKRD52),': [2421], 'interact': [2427, 2559, 3291], 'elongation': [2430], 'Pol': [2431, 2562], 'largely': [2435], 'accumulates': [2436], 'sites,': [2439], 'stimulates': [2441], 'parental': [2445, 2570], 'ANKRD52.28Zhang': [2447], 'al.29Li': [2486], 'Lin': [2494], 'Zhong': [2498], 'Hu': [2502], 'Dai': [2504], 'al.Exon-intron': [2507], 'regulate': [2510], 'nucleus.Nat.': [2514], 'Struct.': [2515], '22:': [2519], '256-264Crossref': [2520], '(1686)': [2523], 'EIciRNA-U1': [2530], 'small': [2531], 'ribonucleoprotein': [2533], '(snRNP)': [2534], 'complexes': [2535], 'U1': [2537, 2552], 'snRNP': [2538, 2553], 'EIciRNAs,': [2540], 'special': [2542], 'circRNAs,': [2545], 'hold': [2548], 'factors': [2549], 'RNA-RNA': [2555], 'interaction,': [2556], 'further': [2558, 3270], 'promoters': [2568], 'expression.': [2575], 'physiological': [2582], 'processes': [2583], 'binding': [2586, 2655, 2705], 'decoys': [2589], 'sponges.': [2591], 'best': [2593, 4342], 'experimentally': [2594], 'supported': [2595], 'example': [2596], 'mannose-binding': [2606], 'lectin': [2607], '(MBL)': [2608], 'locus.16Kristensen': [2609], 'MBL': [2638, 2654], 'significantly': [2640, 3174, 3216], 'contributes': [2641], 'circMBL,': [2646], 'this': [2648], 'dependent': [2651], 'sites.30Ashwal-Fluss': [2656], 'Meyer': [2658], 'Pamudurti': [2660], 'Ivanov': [2662], 'Evantal': [2668], 'Memczak': [2670], 'Rajewsky': [2672, 3693], 'Kadener': [2674], 'competes': [2678], 'pre-mRNA': [2680, 3092], 'splicing.Mol.': [2681], '56:': [2684], '55-66Abstract': [2685], '(1796)': [2693], 'circFOXO3': [2698], 'regulation': [2708], 'protein-protein': [2710], 'interactions.7Du': [2711], '31Du': [2746], 'Yong': [2752, 2795], 'Identifying': [2758, 2801], 'characterizing': [2760, 2803], 'circRNA-protein': [2761, 2804, 2898], 'interaction.Theranostics.': [2762, 2805], '7:': [2764, 2807, 2961, 3398, 3952, 4028], '4183-4191Crossref': [2765, 2808], '(339)': [2768, 2811], 'circ-FOXO3': [2771], 'p53': [2777], 'MDM2,': [2779], 'enhance': [2781], 'breast': [2782], 'cisplatin': [2787], 'doxorubicin.31Du': [2789], 'Schneider': [2814, 3375], 'al.32Schneider': [2816], 'Schreiner': [2820, 3377], 'Starke': [2822], 'Eckhof': [2824], 'Rossbach': [2826], 'Reich': [2828], 'Medenbach': [2830], 'Bindereif': [2832, 3385], 'CircRNA-protein': [2834], 'complexes:': [2835], 'IMP3': [2836, 2854], 'component': [2838], 'defines': [2839], 'subfamily': [2840], 'circRNPs.Sci.': [2842], 'Rep.': [2843, 3528, 3665, 3950, 4026], '31313Crossref': [2846], '(98)': [2849], 'focused': [2852], '(IGF2BP3': [2855], '[Insulin-Like': [2856], 'Growth': [2857], 'Factor': [2858], '2': [2859], 'Binding': [2860], 'Protein': [2861], '3]),': [2862], 'RNA-binding': [2864], 'marker,': [2869], 'investigate': [2871], 'circRNPs': [2872], 'component.': [2877, 2890], 'They': [2878, 3851, 3976, 4118], 'circRNP': [2882], 'families': [2883], 'exist': [2884], 'defined': [2885], 'common': [2888], 'Both': [2891], 'these': [2893, 4148, 4174], 'demonstrated': [2895, 3827], 'dynamics': [2896], 'interaction': [2899], 'tissues': [2902], 'frequently': [2909], 'applied': [2910], 'transcriptome': [2912, 3160], 'studies,': [2913], 'especially': [2914], 'deep': [2915], 'samples': [2921, 3264], 'investigating': [2923], 'cataloguing': [2925], 'alterations': [2926], 'structure': [2931], 'transcriptomes.33Salzman': [2933], 'Gawad': [2935], 'P.L.': [2938], 'Lacayo': [2939], 'Brown': [2941], 'P.O.': [2942], 'predominant': [2947], 'transcript': [2948], 'isoform': [2949], 'hundreds': [2951], 'types.PLoS': [2958], 'ONE.': [2959, 3711], '2012;': [2960], 'e30733Crossref': [2962], '(1598)': [2965], 'tissue-': [2975], 'stage-specific': [2978], 'expression,': [2979], 'abundantly': [2984], 'hematopoietic': [2988, 3266], 'compartment.34Bonizzato': [2989], 'Gaffo': [2991], 'Te': [2993], 'Kronnie': [2994], 'Bortoluzzi': [2996], 'CircRNAs': [2998], 'hematopoiesis': [3000], 'hematological': [3002], 'malignancies.Blood': [3003], 'Cancer': [3004], 'e483Crossref': [3008], '(109)': [3011], 'Platelets': [3014, 3088], 'small,': [3016], 'translationally': [3017], 'competent,': [3018], 'circulating': [3019], 'megakaryocytes35Haemmerle': [3024], 'Stone': [3026, 3098], 'R.L.': [3027, 3099], 'Menter': [3028, 3100], 'D.G.': [3029, 3101], 'Afshar-Kharghan': [3030, 3102], 'Sood': [3032, 3104], 'A.K.': [3033, 3105], 'platelet': [3035, 3107, 3240, 3314], 'lifeline': [3036, 3108], 'opportunities.Cancer': [3041, 3113], '33:': [3044, 3116], '965-983Abstract': [3045, 3117], '(217)': [3053, 3125], 'hemostasis,': [3061], 'angiogenesis,': [3062], 'wound': [3064], 'healing.36Garraud': [3065], 'Cognasse': [3067], 'Are': [3069], 'platelets': [3070, 3155, 3196, 3278, 3289, 3340], 'cells?': [3071], 'And': [3072], 'if': [3073], 'yes,': [3074], 'immune': [3077], 'cells?.Front.': [3078], 'Immunol.': [3079], '70Crossref': [3082], 'capable': [3090], 'mature': [3095, 3220], 'mRNAs.35Haemmerle': [3096], 'Alhasan': [3128], 'al.37Alhasan': [3130], 'A.A.': [3131], 'Izuogu': [3132], 'O.G.': [3133], 'Al-Balool': [3134], 'H.H.': [3135], 'Steyn': [3136], 'J.S.': [3137], 'Evans': [3138], 'Colzani': [3140], 'Ghevaert': [3142], 'Mountford': [3144], 'J.C.': [3145, 4042, 4189], 'Marenah': [3146], 'Elliott': [3148], 'D.J.': [3149, 3493, 3630], 'signature': [3158], 'degradation.Blood.': [3161], '127:': [3163], 'e1-e11Crossref': [3164], '(139)': [3167], 'platelets,': [3177], 'where': [3178], 'generated': [3181, 4089], 'compared': [3185, 3218, 3488, 3869], 'nucleated': [3187], 'types.': [3189], 'Several': [3190], 'were': [3193, 3609, 3981], 'using': [3198, 3261], 'selectively': [3202], 'remove': [3203], 'relative': [3208], 'proportion': [3209], 'cultured': [3213], 'megakaryocytes': [3214], 'lower': [3217], 'platelets.38Sunderland': [3221], 'Skroblin': [3223, 3297], 'P.': [3224, 3298, 3690, 3929, 4005], 'Barwari': [3225, 3299], 'Huntley': [3227, 3301], 'R.P.': [3228, 3302], 'Joshi': [3231, 3305], 'Lovering': [3233, 3307], 'R.C.': [3234, 3308], 'Mayr': [3235, 3309], 'MicroRNA': [3237, 3311], 'reactivity:': [3241, 3315], 'clot': [3243, 3317], 'thickens.Circ.': [3244, 3318], '120:': [3247, 3321], '418-435Crossref': [3248, 3322], '(125)': [3251, 3325], 'primary': [3262], 'patient': [3263], 'malignancies,': [3267], 'gaining': [3269], 'insight': [3271], 'biology': [3274], 'knowledge': [3281, 4277], 'how': [3283], 'mRNAs.38Sunderland': [3295], 'packaged': [3330], 'released': [3332], 'vesicles': [3334, 3615], '(exosomes': [3335], 'microvesicles)': [3337], '(Figure': [3341, 3564], '1).17Bach': [3342], '39Preußer': [3371], 'L.-H.': [3374], 'Hardt': [3379], 'Moebus': [3381], 'Santoso': [3383], 'Selective': [3387], 'release': [3388], 'platelet-derived': [3392], 'extracellular': [3393, 3614], 'vesicles.J.': [3394], 'Extracell.': [3395], 'Vesicles.': [3396], '1424473Crossref': [3399], '(119)': [3402], '40Yang': [3405], 'Fu': [3407], 'Exosomal': [3413], 'non-coding': [3414], 'biomarker.Clin.': [3419], 'Chem.': [3420], 'Lab.': [3421], 'Med.': [3422], '54:': [3424], '1871-1879Crossref': [3425], '(12)': [3428], '41Bach': [3431], 'T.-T.-T.': [3434], 'Y.J.': [3438], 'BMP4': [3445], 'upregulation': [3446], 'acquired': [3450], 'drug': [3451], 'resistance': [3452, 4169], 'fatty': [3454], 'acid': [3455, 4140], 'metabolism': [3456], 'EGFR-mutant': [3458], '817-828Abstract': [3468], '(0)': [3476], 'widely': [3484], 'cells.42Dou': [3490, 3627], 'Cha': [3492, 3629], 'Franklin': [3494, 3631], 'Higginbotham': [3496, 3633], 'J.N.': [3497, 3634], 'Jeppesen': [3498, 3635], 'D.K.': [3499, 3636], 'Weaver': [3500, 3637], 'A.M.': [3501, 3638], 'Prasad': [3502, 3639], 'Levy': [3504, 3641], 'Coffey': [3506, 3643], 'R.J.': [3507, 3644], 'Patton': [3508, 3645], 'J.G.': [3509, 3646], 'down-regulated': [3515, 3652], 'KRAS': [3517, 3623, 3654], 'mutant': [3518, 3624, 3655], 'colon': [3519, 3656], 'transferred': [3525, 3560, 3619, 3662], 'exosomes.Sci.': [3527, 3664], '37982Crossref': [3531, 3668], '(231)': [3534, 3671], 'Sorting': [3537], 'modulated': [3544], 'changes': [3546], 'producer': [3552], 'cells,': [3553, 4239], 'recipient': [3562], '1).12Li': [3565], 'observed': [3611], 'secreted': [3613], 'colorectal': [3625], 'provided': [3677], 'peripheral': [3685, 3835, 3960], 'whole': [3686, 3726, 3849], 'blood,43Memczak': [3687], 'Papavasileiou': [3689], 'Peters': [3691], 'new': [3703], 'putative': [3706], 'blood.PLoS': [3710], 'e0141214Crossref': [3714], '(447)': [3717], 'components': [3724], 'useful': [3730], 'biomarker.44Qian': [3733], 'Lv': [3747, 3795, 3886], 'Xie': [3749, 3797, 3888], 'Bai': [3751, 3799, 3890], 'al.Potential': [3754, 3802, 3893], 'diagnostic': [3755, 3803, 3894, 3944, 4020], 'power': [3756, 3804, 3895], 'active': [3763, 3811, 3867, 3902, 4178], 'pulmonary': [3764, 3812, 3903], 'tuberculosis.EBioMedicine.': [3765, 3813, 3904], '27:': [3767, 3815, 3906], '18-26Abstract': [3768, 3816, 3907], '(47)': [3776, 3824, 3915], 'Qian': [3779], 'al.44Qian': [3781], 'wide': [3828], 'mononuclear': [3837], '(PBMCs),': [3839], 'comparable': [3842], 'landscapes': [3846], 'blood.': [3850], 'difference': [3858], 'PBMCs': [3863], 'patients': [3865, 3964], 'tuberculosis': [3868], 'healthy': [3871], 'controls.44Qian': [3872], 'al.45Zhao': [3920], 'Gao': [3924, 4000], 'Jian': [3926, 4002], 'Hao': [3928, 4004], 'Rao': [3930, 4006], 'Peripheral': [3934, 4010], 'hsa_circ_0124644': [3938, 4014], 'used': [3941, 4017], 'coronary': [3947, 3966, 4023], 'artery': [3948, 3967, 4024], 'disease.Sci.': [3949, 4025], '39918Crossref': [3953, 4029], '(168)': [3956, 4032], 'analyzed': [3959], 'disease': [3968], '(CAD)': [3969], 'control': [3971], 'individuals': [3972], 'microarray.': [3975], 'five': [3978], 'all': [3982], 'CAD': [3986], 'group,': [3987], 'hsa-circ-0124644': [3989], 'had': [3990], 'largest': [3992], 'area': [3993], 'under': [3994], 'curve.45Zhao': [3996], 'Guarnerio': [4035], 'al.46Guarnerio': [4037], 'Bezzi': [4039, 4186], 'Jeong': [4041, 4188], 'Paffenholz': [4043, 4190], 'S.V.': [4044, 4191], 'Berry': [4045, 4192], 'Naldini': [4047, 4194], 'M.M.': [4048, 4195], 'Lo-Coco': [4049, 4196], 'Tay': [4051, 4198], 'Beck': [4053, 4200], 'A.H.': [4054, 4201], 'Pandolfi': [4055, 4202], 'P.P.': [4056, 4203], 'Oncogenic': [4057, 4204], 'fusion-circRNAs': [4060, 4149, 4207], 'cancer-associated': [4063, 4210], 'chromosomal': [4064, 4091, 4211], 'translocations.Cell.': [4065, 4212], '165:': [4067, 4214], '289-302Abstract': [4068, 4215], 'fusion': [4087], 'translocations.16Kristensen': [4092], 'tumor-associated': [4125], 'translocations,': [4126], 'mixed': [4128], 'lineage': [4129], 'leukemia': [4130, 4135], '(MLL)-AF9': [4131], 'acute': [4133], 'myeloid': [4134], '(AML)': [4136], 'promyelocytic': [4138, 4144], 'leukemia-retinoic': [4139], 'receptor-alpha': [4141], '(PML-RARA)': [4142], 'leukemia,': [4145], 'named': [4147], '(f-circRNAs).': [4150], 'f-circRNAs': [4155, 4175, 4228, 4242], '(f-circPR': [4156], 'f-circM9)': [4158], 'promote': [4160], 'viability,': [4162], 'transformation': [4167], 'upon': [4170], 'therapy,': [4171], 'biologically': [4177], 'exert': [4180], 'pro-proliferative': [4181], 'pro-oncogenic': [4183], 'activities.46Guarnerio': [4184], 'MLL-AF9-derived': [4227], 'stimulated': [4229], 'p27': [4233], 'p21': [4235], 'THP1': [4238], 'viability.47Alderton': [4249], 'G.K.': [4250], 'Translocations:': [4251], 'translocations.Nat.': [4255], '16:': [4259], '273Google': [4260], 'To': [4262], 'consider': [4263, 4275], 'aspects': [4270], 'biology,': [4273], 'existing': [4276], 'context': [4280], '48Hanahan': [4303], 'Weinberg': [4305], 'R.A.': [4306], 'Hallmarks': [4307], 'next': [4311], 'generation.Cell.': [4312], '2011;': [4313], '144:': [4314], '646-674Abstract': [4315], '(40224)': [4323], 'serve': [4328], 'regulators': [4331], 'sustained': [4336], 'signaling.': [4338], 'One': [4339], 'examples': [4344], 'circ-FOXO3,': [4346], 'decreased': [4349], 'tumors': [4352], 'affect': [4355], 'FOXO3,': [4356], 'p53,': [4357], 'PUMA': [4359], 'expression.7Du': [4360], 'Sco': [4391]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2913417482', 'counts_by_year': [{'year': 2024, 'cited_by_count': 17}, {'year': 2023, 'cited_by_count': 51}, {'year': 2022, 'cited_by_count': 67}, {'year': 2021, 'cited_by_count': 89}, {'year': 2020, 'cited_by_count': 80}, {'year': 2019, 'cited_by_count': 36}], 'updated_date': '2024-12-20T03:07:25.832873', 'created_date': '2019-02-21'}