Publication Information

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'heterozygous': [103], 'gene': [104], 'mutations': [105], 'familial': [107], 'HLH-associated': [108], 'pathway': [110], 'genes': [111], '(e.g.,': [112], 'PRF1,': [113], 'UNC13D)': [114], 'have': [115, 234], 'been': [116, 134, 235], 'linked': [117], 'substantial': [120], 'subset': [121], 'patients.': [124], 'In': [125, 195, 241], 'addition,': [126], 'pro-inflammatory': [128, 175], 'cytokine': [129, 176, 179, 217, 239, 248], 'environment,': [130], 'particularly': [131], 'IL-6,': [132, 231], 'has': [133], 'shown': [135], 'decrease': [137], 'NK': [138, 145], 'cell': [139], 'function.': [141], 'The': [142, 178], 'inability': [143], 'cells': [146, 151, 160, 200], 'CD8': [149], 'T': [150], 'lyse': [153], 'infected': [154], 'otherwise': [156], 'activated': [157], 'antigen': [158, 207], 'presenting': [159], 'results': [161, 181], 'prolonged': [163], 'cell-to-cell': [164], '(innate': [165], 'adaptive': [167], 'immune': [168, 259], 'cells)': [169], 'interactions': [170], 'amplification': [172], 'cascade.': [177, 240], 'storm': [180], 'macrophages,': [185, 198], 'causing': [186], 'hemophagocytosis,': [187], 'well': [189, 213], 'contributing': [191, 215], 'multi-organ': [193], 'addition': [196, 242], 'dendritic': [199], 'likely': [201], 'play': [202], 'critical': [204], 'role': [205], 'presentation': [208], 'lymphocytes,': [211], 'expression.': [218], 'Several': [219], 'cytokines,': [220], 'including': [221], 'tumor': [222], 'necrosis': [223], 'factor,': [224], 'interferon-gamma,': [225], 'numerous': [227], 'interleukins': [228], '(i.e.,': [229], 'IL-1,': [230], 'IL-18,': [232], 'IL-33),': [233], 'implicated': [236], 'broadly': [244], 'immunosuppressive': [245], 'therapies,': [246], 'novel': [247], 'targeted': [249], 'treatments': [250], 'are': [251], 'being': [252], 'explored': [253], 'dampen': [255], 'overly': [257], 'active': [258], 'response': [260], 'that': [261], 'responsible': [263], 'for': [264], 'much': [265], 'pathology': [268], 'seen': [269], 'MAS.': [271]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2912679257', 'counts_by_year': [{'year': 2024, 'cited_by_count': 66}, {'year': 2023, 'cited_by_count': 88}, {'year': 2022, 'cited_by_count': 115}, {'year': 2021, 'cited_by_count': 125}, {'year': 2020, 'cited_by_count': 131}, {'year': 2019, 'cited_by_count': 13}], 'updated_date': '2024-12-12T02:07:41.643747', 'created_date': '2019-02-21'}