Autocrine CTHRC1 activates hepatic stellate cells and promotes liver fibrosis by activating TGF-β signaling

Name: Work Video:
Duration: 3 min 30 s
Description: Hepatic fibrosis is caused by chronic liver injury and may progress toward liver cirrhosis, and even hepatocellular carcinoma. However, current treatment is not satisfactory. Therefore, there is a mandate to find novel therapeutic targets to improve therapy, and biomarkers to monitor therapeutic response.
Jun Li; Yahui Wang; Mingze Ma; Shu-Heng Jiang; Xueli Zhang; Yanli Zhang; Xiaomei Yang; Chunjie Xu; Guang-Ang Tian; Qing Li; Yang Wang; Lei Zhu; Hui Nie; Mingxuan Feng; Qiang Xia; Jianren Gu; Qing Xu; Zhigang Zhang
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