Title: Clinical and laboratory assessment of efficiency of the use of Gistafen in complex therapy for patients with itching dermatoses
Abstract: The objective: is to study the effect of the antihistamine Gistafen on the dynamics of the clinical picture and laboratory parameters of patients with itching dermatoses, and to assess its acceptability.Materials and methods. Sixty patients with itching dermatoses aged 18 to 65 years were examined. All patients were divided into two representative groups. Patients of the control group along with standard therapy, corresponding to the established diagnosis, took an antihistamine – loratadine. Patients of the main group received an antihistamine Gistafen. Duration of prescribing – 14 days.Results. As a result of the investigation, it was revealed that patients of the main group, in comparison with the control group, had the decrease of clinical symptoms in a short period of time, the level of serotonin decreased, the activity of diaminoxidase increased, and patients quality of life improved significantly.Conclusion. The use of Gistafen is an effective treatment for patients with itching dermatoses, as it provides an evident antipruritic effect, rapid relief of clinical symptoms according to the Dermatological index of scale of symptoms, significantly improves their quality of life according to DQLI scale.