Publication Information

{'id': 'https://openalex.org/W2904802473', 'doi': 'https://doi.org/10.1042/bj3550059', 'title': 'Selective recognition of inositol phosphates by subtypes of the inositol trisphosphate receptor', 'display_name': 'Selective recognition of inositol phosphates by subtypes of the inositol trisphosphate receptor', 'publication_year': 2001, 'publication_date': '2001-02-26', 'ids': {'openalex': 'https://openalex.org/W2904802473', 'doi': 'https://doi.org/10.1042/bj3550059', 'mag': '2904802473'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1042/bj3550059', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S44425019', 'display_name': 'Biochemical Journal', 'issn_l': '0264-6021', 'issn': ['0264-6021', '1470-8728'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311608', 'host_organization_name': 'Portland Press', 'host_organization_lineage': ['https://openalex.org/P4310311715', 'https://openalex.org/P4310311608'], 'host_organization_lineage_names': ['Biochemical Society', 'Portland Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5065776554', 'display_name': 'Edmund P. Nerou', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I241749', 'display_name': 'University of Cambridge', 'ror': 'https://ror.org/013meh722', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I241749']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Edmund P. NEROU', 'raw_affiliation_strings': ['Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QJ, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QJ, U.K.', 'institution_ids': ['https://openalex.org/I241749']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023315844', 'display_name': 'Andrew M. Riley', 'orcid': 'https://orcid.org/0000-0001-9003-3540'}, 'institutions': [{'id': 'https://openalex.org/I51601045', 'display_name': 'University of Bath', 'ror': 'https://ror.org/002h8g185', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I51601045']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Andrew M. RILEY', 'raw_affiliation_strings': ['Wolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Wolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, U.K.', 'institution_ids': ['https://openalex.org/I51601045']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113898464', 'display_name': 'Barry V. L. Potter', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I51601045', 'display_name': 'University of Bath', 'ror': 'https://ror.org/002h8g185', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I51601045']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Barry V. L. POTTER', 'raw_affiliation_strings': ['Wolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Wolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, U.K.', 'institution_ids': ['https://openalex.org/I51601045']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5040503192', 'display_name': 'Colin W. Taylor', 'orcid': 'https://orcid.org/0000-0001-7771-1044'}, 'institutions': [{'id': 'https://openalex.org/I241749', 'display_name': 'University of Cambridge', 'ror': 'https://ror.org/013meh722', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I241749']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Colin W. TAYLOR', 'raw_affiliation_strings': ['Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QJ, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QJ, U.K.', 'institution_ids': ['https://openalex.org/I241749']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.033, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 30, 'citation_normalized_percentile': {'value': 0.753139, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 88, 'max': 89}, 'biblio': {'volume': '355', 'issue': '1', 'first_page': '59', 'last_page': '69'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11075', 'display_name': 'Insect Resistance and Genetics', 'score': 0.9318, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11075', 'display_name': 'Insect Resistance and Genetics', 'score': 0.9318, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10570', 'display_name': 'Drug Transport and Resistance Mechanisms', 'score': 0.9134, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10450', 'display_name': 'Aquaculture Nutrition and Growth', 'score': 0.9023, 'subfield': {'id': 'https://openalex.org/subfields/1104', 'display_name': 'Aquatic Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/inositol-phosphate', 'display_name': 'Inositol phosphate', 'score': 0.74280506}, {'id': 'https://openalex.org/keywords/inositol-trisphosphate-receptor', 'display_name': 'Inositol trisphosphate receptor', 'score': 0.68762916}, {'id': 'https://openalex.org/keywords/inositol-trisphosphate', 'display_name': 'Inositol trisphosphate', 'score': 0.46182567}, {'id': 'https://openalex.org/keywords/affinities', 'display_name': 'Affinities', 'score': 0.43799582}], 'concepts': [{'id': 'https://openalex.org/C2777427919', 'wikidata': 'https://www.wikidata.org/wiki/Q407997', 'display_name': 'Inositol', 'level': 3, 'score': 0.8213988}, {'id': 'https://openalex.org/C2778618036', 'wikidata': 'https://www.wikidata.org/wiki/Q2878809', 'display_name': 'Inositol phosphate', 'level': 4, 'score': 0.74280506}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.73462015}, {'id': 'https://openalex.org/C152624196', 'wikidata': 'https://www.wikidata.org/wiki/Q418917', 'display_name': 'Inositol trisphosphate receptor', 'level': 4, 'score': 0.68762916}, {'id': 'https://openalex.org/C118792377', 'wikidata': 'https://www.wikidata.org/wiki/Q108584245', 'display_name': 'Selectivity', 'level': 3, 'score': 0.49987102}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.47628397}, {'id': 'https://openalex.org/C2781387506', 'wikidata': 'https://www.wikidata.org/wiki/Q138145', 'display_name': 'Inositol trisphosphate', 'level': 4, 'score': 0.46182567}, {'id': 'https://openalex.org/C98539663', 'wikidata': 'https://www.wikidata.org/wiki/Q220599', 'display_name': 'Cytosol', 'level': 3, 'score': 0.44761875}, {'id': 'https://openalex.org/C2780283098', 'wikidata': 'https://www.wikidata.org/wiki/Q4688960', 'display_name': 'Affinities', 'level': 2, 'score': 0.43799582}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.43705866}, {'id': 'https://openalex.org/C71240020', 'wikidata': 'https://www.wikidata.org/wiki/Q186011', 'display_name': 'Stereochemistry', 'level': 1, 'score': 0.43618974}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.36227202}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.32964224}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.32084686}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.11920905}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.06607786}, {'id': 'https://openalex.org/C161790260', 'wikidata': 'https://www.wikidata.org/wiki/Q82264', 'display_name': 'Catalysis', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1042/bj3550059', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S44425019', 'display_name': 'Biochemical Journal', 'issn_l': '0264-6021', 'issn': ['0264-6021', '1470-8728'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311608', 'host_organization_name': 'Portland Press', 'host_organization_lineage': ['https://openalex.org/P4310311715', 'https://openalex.org/P4310311608'], 'host_organization_lineage_names': ['Biochemical Society', 'Portland Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W2414370287', 'https://openalex.org/W2401644871', 'https://openalex.org/W2401626197', 'https://openalex.org/W2337457843', 'https://openalex.org/W2123890105', 'https://openalex.org/W2074993713', 'https://openalex.org/W2064525306', 'https://openalex.org/W2063903820', 'https://openalex.org/W1984139268', 'https://openalex.org/W1499372908'], 'abstract_inverted_index': {'Synthetic': [0], 'analogues': [1], 'of': [2, 7, 15, 24, 54, 107, 150, 154, 167, 179, 186, 198, 207, 230, 243, 247, 258, 263], 'inositol': [3], 'trisphosphate': [4], '(IP3),': [5], 'all': [6, 100], 'which': [8, 146], 'included': [9], 'structures': [10], 'equivalent': [11], 'to': [12, 19, 91, 145], 'the': [13, 21, 51, 55, 85, 103, 114, 122, 143, 151, 165, 187, 196, 208, 228, 239, 244, 254], '4,5-bisphosphate': [14], '(1,4,5)IP3,': [16], 'were': [17, 60], 'used': [18], 'probe': [20], 'recognition': [22, 245], 'properties': [23, 246], 'rat': [25], 'full-length': [26], 'type': [27, 61, 71, 96, 170, 201, 222, 233], '1,': [28], '2': [29, 66, 191, 202], 'and': [30, 121, 160, 192, 203, 225, 251, 256], '3': [31, 62, 204, 223, 234], 'IP3': [32, 248], 'receptors': [33], 'expressed': [34], 'in': [35, 47, 88, 131, 142, 176], 'insect': [36], 'Spodoptera': [37], 'frugiperda': [38], '9': [39], 'cells.': [40], 'Using': [41], 'equilibrium': [42], 'competition': [43], 'binding': [44, 77, 137], 'with': [45], '[3H](1,4,5)IP3': [46], 'Ca2+-free': [48], 'cytosol-like': [49], 'medium,': [50], 'relative': [52], 'affinities': [53], 'receptor': [56, 249], 'subtypes': [57, 86, 140, 250], 'for': [58, 111, 164, 169, 200, 227, 232], '(1,4,5)IP3': [59, 76, 108, 155, 259], '(Kd': [63, 67, 73], '=': [64, 68, 74], '11±2nM)>type': [65], '17±2nM)': [69], '>': [70, 95], '1': [72, 94, 171], '24±4nM).': [75], 'was': [78, 109, 126, 218], 'reversibly': [79], 'stimulated': [80], 'by': [81, 214, 221], 'increased': [82], 'pH,': [83], 'but': [84], 'differed': [87, 141, 175], 'their': [89, 177], 'sensitivity': [90], 'pH': [92], '(type': [93, 156], '2>type': [97, 158], '3).': [98], 'For': [99], 'three': [101], 'subtypes,': [102], 'equatorial': [104, 115], '6-hydroxy': [105], 'group': [106, 117, 125, 153, 189, 210], 'essential': [110], 'high-affinity': [112], 'binding,': [113], '3-hydroxy': [116, 152, 209], 'significantly': [118], 'improved': [119, 136], 'affinity,': [120], 'axial': [123], '2-hydroxy': [124, 188], 'insignificant;': [127], 'a': [128, 134], '1-phosphate': [129], '(or': [130], 'its': [132, 212], 'absence,': [133], '2-phosphate)': [135], 'affinity.': [138], 'The': [139], 'extents': [144], 'they': [147], 'tolerated': [148, 220], 'inversion': [149], '1>type': [157], '3),': [159], 'this': [161], 'probably': [162], 'accounts': [163, 226], 'selectivity': [166, 197, 229], '(1,4,6)IP3': [168], 'receptors.': [172, 205, 235], 'They': [173], 'also': [174], 'tolerance': [178], 'inversion,': [180], 'removal': [181], 'or': [182, 211, 216], 'substitution': [183], '(by': [184], 'phosphate)': [185], '(types': [190], '3>type': [193], '1),': [194], 'hence': [195], '(1,2,4,5)IP4': [199], 'Removal': [206], 'replacement': [213], 'fluorine': [215], 'CH2OH': [217], 'best': [219], 'receptors,': [224], '3-deoxy(1,4,5)IP3': [231], 'Our': [236], 'results': [237], 'provide': [238], 'first': [240], 'systematic': [241], 'analysis': [242], 'have': [252], 'identified': [253], '2-': [255], '3-positions': [257], 'as': [260], 'key': [261], 'determinants': [262], 'subtype': [264], 'selectivity.': [265]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2904802473', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-17T09:52:08.586917', 'created_date': '2018-12-22'}