Publication Information

{'id': 'https://openalex.org/W2902340288', 'doi': 'https://doi.org/10.3390/v10120678', 'title': 'Identification of Diaryl-Quinoline Compounds as Entry Inhibitors of Ebola Virus', 'display_name': 'Identification of Diaryl-Quinoline Compounds as Entry Inhibitors of Ebola Virus', 'publication_year': 2018, 'publication_date': '2018-11-30', 'ids': {'openalex': 'https://openalex.org/W2902340288', 'doi': 'https://doi.org/10.3390/v10120678', 'mag': '2902340288', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/30513600', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6315506'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/v10120678', 'pdf_url': 'https://www.mdpi.com/1999-4915/10/12/678/pdf?version=1543564957', 'source': {'id': 'https://openalex.org/S55776271', 'display_name': 'Viruses', 'issn_l': '1999-4915', 'issn': ['1999-4915'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.mdpi.com/1999-4915/10/12/678/pdf?version=1543564957', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5109919580', 'display_name': 'Qinghua Cui', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I134738993', 'display_name': 'Shandong University of Traditional Chinese Medicine', 'ror': 'https://ror.org/0523y5c19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I134738993']}, {'id': 'https://openalex.org/I39422238', 'display_name': 'University of Illinois Chicago', 'ror': 'https://ror.org/02mpq6x41', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I39422238']}], 'countries': ['CN', 'US'], 'is_corresponding': True, 'raw_author_name': 'Qinghua Cui', 'raw_affiliation_strings': ['College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China', 'Department of Microbiology and Immunology, College of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA'], 'affiliations': [{'raw_affiliation_string': 'College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China', 'institution_ids': ['https://openalex.org/I134738993']}, {'raw_affiliation_string': 'Department of Microbiology and Immunology, College of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA', 'institution_ids': ['https://openalex.org/I39422238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044248887', 'display_name': 'Han Cheng', 'orcid': 'https://orcid.org/0000-0002-9464-8611'}, 'institutions': [{'id': 'https://openalex.org/I39422238', 'display_name': 'University of Illinois Chicago', 'ror': 'https://ror.org/02mpq6x41', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I39422238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Han Cheng', 'raw_affiliation_strings': ['Department of Microbiology and Immunology, College of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology and Immunology, College of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA', 'institution_ids': ['https://openalex.org/I39422238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049308978', 'display_name': 'Rui Xiong', 'orcid': 'https://orcid.org/0000-0002-6350-9037'}, 'institutions': [{'id': 'https://openalex.org/I39422238', 'display_name': 'University of Illinois Chicago', 'ror': 'https://ror.org/02mpq6x41', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I39422238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Rui Xiong', 'raw_affiliation_strings': ['Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, and UICentre, University of Illinois at Chicago, Chicago, IL 60612, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, and UICentre, University of Illinois at Chicago, Chicago, IL 60612, USA', 'institution_ids': ['https://openalex.org/I39422238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100363254', 'display_name': 'Gang Zhang', 'orcid': 'https://orcid.org/0000-0003-0774-5710'}, 'institutions': [{'id': 'https://openalex.org/I200296433', 'display_name': 'Chinese Academy of Medical Sciences & Peking Union Medical College', 'ror': 'https://ror.org/02drdmm93', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I200296433']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Gang Zhang', 'raw_affiliation_strings': ['State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, China', 'institution_ids': ['https://openalex.org/I200296433']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064387517', 'display_name': 'Ruikun Du', 'orcid': 'https://orcid.org/0000-0002-9172-7824'}, 'institutions': [{'id': 'https://openalex.org/I134738993', 'display_name': 'Shandong University of Traditional Chinese Medicine', 'ror': 'https://ror.org/0523y5c19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I134738993']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ruikun Du', 'raw_affiliation_strings': ['College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China'], 'affiliations': [{'raw_affiliation_string': 'College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China', 'institution_ids': ['https://openalex.org/I134738993']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031518827', 'display_name': 'Manu Anantpadma', 'orcid': 'https://orcid.org/0000-0001-5796-532X'}, 'institutions': [{'id': 'https://openalex.org/I1289525096', 'display_name': 'Texas Biomedical Research Institute', 'ror': 'https://ror.org/00wbskb04', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1289525096']}, {'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Manu Anantpadma', 'raw_affiliation_strings': ['Department of Microbiology, Boston University, National Emerging Infectious Diseases Laboratories, 401P, 620 Albany Street, Boston, MA 02118, USA', 'Department of Virology and Immunology, Texas Biomedical Research Institute, San Antonio, TX 78227, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Virology and Immunology, Texas Biomedical Research Institute, San Antonio, TX 78227, USA', 'institution_ids': ['https://openalex.org/I1289525096']}, {'raw_affiliation_string': 'Department of Microbiology, Boston University, National Emerging Infectious Diseases Laboratories, 401P, 620 Albany Street, Boston, MA 02118, USA', 'institution_ids': ['https://openalex.org/I111088046']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042358991', 'display_name': 'Robert A. Davey', 'orcid': 'https://orcid.org/0000-0001-9168-2892'}, 'institutions': [{'id': 'https://openalex.org/I1289525096', 'display_name': 'Texas Biomedical Research Institute', 'ror': 'https://ror.org/00wbskb04', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1289525096']}, {'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Robert A. Davey', 'raw_affiliation_strings': ['Department of Microbiology, Boston University, National Emerging Infectious Diseases Laboratories, 401P, 620 Albany Street, Boston, MA 02118, USA', 'Department of Virology and Immunology, Texas Biomedical Research Institute, San Antonio, TX 78227, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Virology and Immunology, Texas Biomedical Research Institute, San Antonio, TX 78227, USA', 'institution_ids': ['https://openalex.org/I1289525096']}, {'raw_affiliation_string': 'Department of Microbiology, Boston University, National Emerging Infectious Diseases Laboratories, 401P, 620 Albany Street, Boston, MA 02118, USA', 'institution_ids': ['https://openalex.org/I111088046']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5001046842', 'display_name': 'Lijun Rong', 'orcid': 'https://orcid.org/0000-0003-3938-0445'}, 'institutions': [{'id': 'https://openalex.org/I39422238', 'display_name': 'University of Illinois Chicago', 'ror': 'https://ror.org/02mpq6x41', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I39422238']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Lijun Rong', 'raw_affiliation_strings': ['Department of Microbiology and Immunology, College of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology and Immunology, College of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA', 'institution_ids': ['https://openalex.org/I39422238']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 5, 'corresponding_author_ids': ['https://openalex.org/A5109919580', 'https://openalex.org/A5001046842'], 'corresponding_institution_ids': ['https://openalex.org/I134738993', 'https://openalex.org/I39422238', 'https://openalex.org/I39422238'], 'apc_list': {'value': 2600, 'currency': 'CHF', 'value_usd': 2815, 'provenance': 'doaj'}, 'apc_paid': {'value': 2600, 'currency': 'CHF', 'value_usd': 2815, 'provenance': 'doaj'}, 'fwci': 2.208, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 31, 'citation_normalized_percentile': {'value': 0.832229, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '10', 'issue': '12', 'first_page': '678', 'last_page': '678'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11581', 'display_name': 'Viral Infections and Outbreaks Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11581', 'display_name': 'Viral Infections and Outbreaks Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10340', 'display_name': 'Hepatitis B Virus Studies', 'score': 0.9943, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12047', 'display_name': 'Viral Infections and Vectors', 'score': 0.9939, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/vp40', 'display_name': 'VP40', 'score': 0.768641}, {'id': 'https://openalex.org/keywords/ebolavirus', 'display_name': 'Ebolavirus', 'score': 0.7006154}, {'id': 'https://openalex.org/keywords/entry-inhibitor', 'display_name': 'Entry inhibitor', 'score': 0.5027242}], 'concepts': [{'id': 'https://openalex.org/C2777469322', 'wikidata': 'https://www.wikidata.org/wiki/Q8064876', 'display_name': 'Ebola virus', 'level': 3, 'score': 0.9842714}, {'id': 'https://openalex.org/C86295872', 'wikidata': 'https://www.wikidata.org/wiki/Q24779573', 'display_name': 'VP40', 'level': 4, 'score': 0.768641}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.71701264}, {'id': 'https://openalex.org/C2909623084', 'wikidata': 'https://www.wikidata.org/wiki/Q5331908', 'display_name': 'Ebolavirus', 'level': 4, 'score': 0.7006154}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.62103266}, {'id': 'https://openalex.org/C2776997796', 'wikidata': 'https://www.wikidata.org/wiki/Q1345259', 'display_name': 'Entry inhibitor', 'level': 5, 'score': 0.5027242}, {'id': 'https://openalex.org/C58475186', 'wikidata': 'https://www.wikidata.org/wiki/Q4118894', 'display_name': 'Viral entry', 'level': 4, 'score': 0.45317653}, {'id': 'https://openalex.org/C108625454', 'wikidata': 'https://www.wikidata.org/wiki/Q187126', 'display_name': 'Glycoprotein', 'level': 2, 'score': 0.42648768}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.38620377}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.36313927}, {'id': 'https://openalex.org/C140704245', 'wikidata': 'https://www.wikidata.org/wiki/Q3933202', 'display_name': 'Viral replication', 'level': 3, 'score': 0.3045547}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.12353504}], 'mesh': [{'descriptor_ui': 'D000998', 'descriptor_name': 'Antiviral Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D019587', 'descriptor_name': 'Dietary Supplements', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D029043', 'descriptor_name': 'Ebolavirus', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D029043', 'descriptor_name': 'Ebolavirus', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D019142', 'descriptor_name': 'Hemorrhagic Fever, Ebola', 'qualifier_ui': 'Q000821', 'qualifier_name': 'virology', 'is_major_topic': True}, {'descriptor_ui': 'D011804', 'descriptor_name': 'Quinolines', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D053586', 'descriptor_name': 'Virus Internalization', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D000998', 'descriptor_name': 'Antiviral Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000998', 'descriptor_name': 'Antiviral Agents', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004353', 'descriptor_name': 'Drug Evaluation, Preclinical', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004353', 'descriptor_name': 'Drug Evaluation, Preclinical', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D029043', 'descriptor_name': 'Ebolavirus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019142', 'descriptor_name': 'Hemorrhagic Fever, Ebola', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D057166', 'descriptor_name': 'High-Throughput Screening Assays', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020128', 'descriptor_name': 'Inhibitory Concentration 50', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008826', 'descriptor_name': 'Microbial Sensitivity Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008958', 'descriptor_name': 'Models, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008968', 'descriptor_name': 'Molecular Conformation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015394', 'descriptor_name': 'Molecular Structure', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011804', 'descriptor_name': 'Quinolines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011804', 'descriptor_name': 'Quinolines', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D013329', 'descriptor_name': 'Structure-Activity Relationship', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053586', 'descriptor_name': 'Virus Internalization', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014779', 'descriptor_name': 'Virus Replication', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014779', 'descriptor_name': 'Virus Replication', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/v10120678', 'pdf_url': 'https://www.mdpi.com/1999-4915/10/12/678/pdf?version=1543564957', 'source': {'id': 'https://openalex.org/S55776271', 'display_name': 'Viruses', 'issn_l': '1999-4915', 'issn': ['1999-4915'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/c815d3c76d364a4684c58733b2cc5132', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc6315506', 'pdf_url': 'https://europepmc.org/articles/pmc6315506?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315506', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/30513600', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/v10120678', 'pdf_url': 'https://www.mdpi.com/1999-4915/10/12/678/pdf?version=1543564957', 'source': {'id': 'https://openalex.org/S55776271', 'display_name': 'Viruses', 'issn_l': '1999-4915', 'issn': ['1999-4915'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.84}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 43, 'referenced_works': ['https://openalex.org/W1925504181', 'https://openalex.org/W1967023731', 'https://openalex.org/W1969237277', 'https://openalex.org/W1971292277', 'https://openalex.org/W1998370052', 'https://openalex.org/W2003408366', 'https://openalex.org/W2005798703', 'https://openalex.org/W2043620814', 'https://openalex.org/W2043829974', 'https://openalex.org/W2066774442', 'https://openalex.org/W2072154238', 'https://openalex.org/W2081524511', 'https://openalex.org/W2081719521', 'https://openalex.org/W2094993149', 'https://openalex.org/W2107717338', 'https://openalex.org/W2113925456', 'https://openalex.org/W2117671399', 'https://openalex.org/W2122527653', 'https://openalex.org/W2130276289', 'https://openalex.org/W2130901375', 'https://openalex.org/W2138289533', 'https://openalex.org/W2145137218', 'https://openalex.org/W2150837053', 'https://openalex.org/W2152808878', 'https://openalex.org/W2156488043', 'https://openalex.org/W2162395676', 'https://openalex.org/W2166553704', 'https://openalex.org/W2168444132', 'https://openalex.org/W2190190975', 'https://openalex.org/W2262551230', 'https://openalex.org/W2292021561', 'https://openalex.org/W2298069345', 'https://openalex.org/W2346312782', 'https://openalex.org/W2466466163', 'https://openalex.org/W2541191377', 'https://openalex.org/W2647136810', 'https://openalex.org/W2753166108', 'https://openalex.org/W2756098300', 'https://openalex.org/W2765514188', 'https://openalex.org/W2777797644', 'https://openalex.org/W2794972396', 'https://openalex.org/W2801438367', 'https://openalex.org/W2847396516'], 'related_works': ['https://openalex.org/W3204533495', 'https://openalex.org/W3116349712', 'https://openalex.org/W2968139870', 'https://openalex.org/W2902340288', 'https://openalex.org/W2620609420', 'https://openalex.org/W2605634853', 'https://openalex.org/W2515934800', 'https://openalex.org/W2258116701', 'https://openalex.org/W2171864254', 'https://openalex.org/W2097906623'], 'abstract_inverted_index': {'Ebola': [0, 7, 15, 38, 102, 112, 157, 165, 173], 'virus': [1, 8, 16, 46, 61, 88, 113, 166, 174], 'is': [2, 18, 31, 41, 55], 'the': [3, 22, 32, 37, 45, 51, 68, 93, 98, 101, 109, 127, 145, 148], 'causative': [4], 'agent': [5], 'of': [6, 14, 36, 92, 100, 119, 124, 141, 147, 187], 'disease': [9], 'in': [10, 176], 'humans.': [11], 'The': [12, 122], 'lethality': [13], 'infection': [17], 'about': [19], '50%,': [20], 'supporting': [21], 'urgent': [23], 'need': [24], 'to': [25, 47, 126, 136, 151], 'develop': [26], 'anti-Ebola': [27, 60, 87, 212], 'drugs.': [28], 'Glycoprotein': [29], '(GP)': [30], 'only': [33], 'surface': [34], 'protein': [35], 'virus,': [39], 'which': [40, 206], 'functionally': [42], 'critical': [43], 'for': [44, 59, 86, 211], 'attach': [48], 'and': [49, 54, 133], 'enter': [50], 'host': [52], 'cells,': [53], 'a': [56, 78, 198], 'promising': [57], 'target': [58], 'drug': [62, 213], 'development.': [63, 214], 'In': [64, 190], 'this': [65], 'study,': [66], 'using': [67], 'recombinant': [69], 'HIV-1/Ebola': [70], 'pseudovirus': [71], 'platform': [72], 'we': [73, 76, 192], 'previously': [74], 'established,': [75], 'evaluated': [77], 'small': [79], 'molecule': [80], 'library': [81], 'containing': [82], 'various': [83], 'quinoline': [84, 94], 'compounds': [85, 95], 'entry': [89, 99, 114, 167, 204], 'inhibitors.': [90], 'Some': [91], 'specifically': [96], 'inhibited': [97, 171], 'virus.': [103], 'Among': [104], 'them,': [105], 'compound': [106, 154, 169], 'SYL1712': [107, 125, 155, 170], 'was': [108, 130, 134], 'most': [110], 'potent': [111], 'inhibitor': [115], 'with': [116, 138, 162, 184, 197], 'an': [117, 164, 185], 'IC50': [118, 186], '~1': [120], 'μM.': [121, 189], 'binding': [123], 'vial': [128], 'glycoprotein': [129], 'computationally': [131], 'modeled': [132], 'predicted': [135], 'interact': [137], 'specific': [139], 'residues': [140], 'GP.': [142], 'We': [143], 'used': [144], 'time': [146], 'addition': [149], 'assay': [150], 'show': [152], 'that': [153], 'blocks': [156], 'GP-mediated': [158], 'entry.': [159], 'Finally,': [160], 'consistent': [161], 'being': [163], 'inhibitor,': [168], 'infectious': [172], 'replication': [175], 'tissue': [177], 'culture': [178], 'under': [179], 'biosafety': [180], 'level': [181], '4': [182], 'containment,': [183], '2': [188], 'conclusion,': [191], 'identified': [193], 'several': [194], 'related': [195], 'molecules': [196], 'diaryl-quinoline': [199], 'scaffold': [200], 'as': [201], 'potential': [202], 'anti-EBOV': [203], 'inhibitors,': [205], 'can': [207], 'be': [208], 'further': [209], 'optimized': [210]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2902340288', 'counts_by_year': [{'year': 2024, 'cited_by_count': 9}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 6}, {'year': 2021, 'cited_by_count': 8}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 3}], 'updated_date': '2025-01-07T22:32:02.356497', 'created_date': '2018-12-11'}