BOSENTAN - endothelin receptor antagonist

Name: Work Video:
Duration: 3 min 30 s
Kiran Kumar Singal; Neerja Singal; Paras Passi; Mohit Singla; Nitin Gupta; Sumit Gautam
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'Artery': [17], 'Hypertension)': [18], 'patients.': [19], 'Although': [20], 'it': [21], 'is': [22, 58, 73], 'not': [23], 'clear': [24], 'if': [25], 'increases': [27], 'levels': [31], 'are': [32], 'a': [33, 36, 45, 74], 'cause': [34], 'or': [35], 'consequence': [37], 'PH': [39], 'Hypertension),': [41], 'data': [43], 'supports': [44], 'prominent': [46], 'role': [47], 'for': [48], 'pathogenesis': [54], 'PAH.': [56], 'Bosentan': [57], 'an': [59], 'receptor': [61, 88], 'antagonist': [62, 89], 'used': [63], 'treatment': [66], 'Primary': [68], 'pulmonary': [69, 115], 'hypertension': [70], '(PPH)': [71], 'which': [72], 'progressive': [75], 'disease': [76], 'with': [77, 112], 'high': [78], 'mortality': [79], 'administration': [81], 'orally': [84], 'active,': [85], 'dual': [86], 'bosentan': [90, 103], 'improves': [91], 'exercise': [92], 'endurance,': [93], 'haemodynamics,': [94], 'functional': [96], 'class': [97], 'over': [98], 'short': [100], 'term.': [101], 'First-line': [102], 'therapy': 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