Publication Information

{'id': 'https://openalex.org/W2894284291', 'doi': 'https://doi.org/10.1093/jjco/hyy138', 'title': 'Combination of transarterial chemoembolization and sorafenib improves outcomes of unresectable hepatocellular carcinoma: an updated systematic review and meta-analysis', 'display_name': 'Combination of transarterial chemoembolization and sorafenib improves outcomes of unresectable hepatocellular carcinoma: an updated systematic review and meta-analysis', 'publication_year': 2018, 'publication_date': '2018-09-18', 'ids': {'openalex': 'https://openalex.org/W2894284291', 'doi': 'https://doi.org/10.1093/jjco/hyy138', 'mag': '2894284291', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/30272196'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/jjco/hyy138', 'pdf_url': 'https://academic.oup.com/jjco/article-pdf/48/12/1058/26751318/hyy138.pdf', 'source': {'id': 'https://openalex.org/S149902429', 'display_name': 'Japanese Journal of Clinical Oncology', 'issn_l': '0368-2811', 'issn': ['0368-2811', '1465-3621'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://academic.oup.com/jjco/article-pdf/48/12/1058/26751318/hyy138.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5038925047', 'display_name': 'Piaopiao Jin', 'orcid': 'https://orcid.org/0000-0002-2220-8959'}, 'institutions': [{'id': 'https://openalex.org/I27781120', 'display_name': 'Wenzhou Medical University', 'ror': 'https://ror.org/00rd5t069', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I27781120']}, {'id': 'https://openalex.org/I2801769982', 'display_name': 'First Affiliated Hospital of Wenzhou Medical University', 'ror': 'https://ror.org/03cyvdv85', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801769982']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Piao-Piao Jin', 'raw_affiliation_strings': ['Department of Gastroenterology, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Gastroenterology, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China', 'institution_ids': ['https://openalex.org/I27781120', 'https://openalex.org/I2801769982']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102331937', 'display_name': 'Shiyi Shao', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210158318', 'display_name': 'Second Affiliated Hospital of Zhejiang University', 'ror': 'https://ror.org/059cjpv64', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210158318']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Shi-Yi Shao', 'raw_affiliation_strings': ['Department of Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China', 'institution_ids': ['https://openalex.org/I4210158318']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020774547', 'display_name': 'Wangteng Wu', 'orcid': 'https://orcid.org/0000-0001-8735-7587'}, 'institutions': [{'id': 'https://openalex.org/I4210158318', 'display_name': 'Second Affiliated Hospital of Zhejiang University', 'ror': 'https://ror.org/059cjpv64', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210158318']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wang-Teng Wu', 'raw_affiliation_strings': ['Department of Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China', 'institution_ids': ['https://openalex.org/I4210158318']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101680596', 'display_name': 'Xinyu Zhao', 'orcid': 'https://orcid.org/0000-0002-2811-8735'}, 'institutions': [{'id': 'https://openalex.org/I4210158318', 'display_name': 'Second Affiliated Hospital of Zhejiang University', 'ror': 'https://ror.org/059cjpv64', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210158318']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xin-Yu Zhao', 'raw_affiliation_strings': ['Department of Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China', 'institution_ids': ['https://openalex.org/I4210158318']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111870838', 'display_name': 'Bingfeng Huang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210158318', 'display_name': 'Second Affiliated Hospital of Zhejiang University', 'ror': 'https://ror.org/059cjpv64', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210158318']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Bing-Feng Huang', 'raw_affiliation_strings': ['Department of Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China', 'institution_ids': ['https://openalex.org/I4210158318']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046579422', 'display_name': 'Qihan Fu', 'orcid': 'https://orcid.org/0000-0003-2967-1812'}, 'institutions': [{'id': 'https://openalex.org/I4210158318', 'display_name': 'Second Affiliated Hospital of Zhejiang University', 'ror': 'https://ror.org/059cjpv64', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210158318']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Qi-Han Fu', 'raw_affiliation_strings': ['Department of Oncology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China', 'institution_ids': ['https://openalex.org/I4210158318']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085378930', 'display_name': 'Risheng Que', 'orcid': 'https://orcid.org/0000-0003-3242-5639'}, 'institutions': [{'id': 'https://openalex.org/I4210158318', 'display_name': 'Second Affiliated Hospital of Zhejiang University', 'ror': 'https://ror.org/059cjpv64', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210158318']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ri-Sheng Que', 'raw_affiliation_strings': ['Department of Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China', 'institution_ids': ['https://openalex.org/I4210158318']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5067811638', 'display_name': 'Qi-Da Hu', 'orcid': 'https://orcid.org/0000-0002-9092-7808'}, 'institutions': [{'id': 'https://openalex.org/I4210158318', 'display_name': 'Second Affiliated Hospital of Zhejiang University', 'ror': 'https://ror.org/059cjpv64', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210158318']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Qi-Da Hu', 'raw_affiliation_strings': ['Department of Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China', 'institution_ids': ['https://openalex.org/I4210158318']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5067811638'], 'corresponding_institution_ids': ['https://openalex.org/I4210158318'], 'apc_list': {'value': 3300, 'currency': 'USD', 'value_usd': 3300, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.564, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 19, 'citation_normalized_percentile': {'value': 0.383881, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '48', 'issue': '12', 'first_page': '1058', 'last_page': '1069'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10073', 'display_name': 'Hepatocellular Carcinoma Treatment and Prognosis', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2721', 'display_name': 'Hepatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10073', 'display_name': 'Hepatocellular Carcinoma Treatment and Prognosis', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2721', 'display_name': 'Hepatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10417', 'display_name': 'Lung Cancer Treatments and Mutations', 'score': 0.9964, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11364', 'display_name': 'Cholangiocarcinoma and Gallbladder Cancer Studies', 'score': 0.9962, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.90392005}, {'id': 'https://openalex.org/C207103383', 'wikidata': 'https://www.wikidata.org/wiki/Q3930246', 'display_name': 'Hazard ratio', 'level': 3, 'score': 0.85065615}, {'id': 'https://openalex.org/C44249647', 'wikidata': 'https://www.wikidata.org/wiki/Q208498', 'display_name': 'Confidence interval', 'level': 2, 'score': 0.7594915}, {'id': 'https://openalex.org/C2778019345', 'wikidata': 'https://www.wikidata.org/wiki/Q1148337', 'display_name': 'Hepatocellular carcinoma', 'level': 2, 'score': 0.7367166}, {'id': 'https://openalex.org/C82789193', 'wikidata': 'https://www.wikidata.org/wiki/Q2142611', 'display_name': 'Relative risk', 'level': 3, 'score': 0.7090535}, {'id': 'https://openalex.org/C2778695046', 'wikidata': 'https://www.wikidata.org/wiki/Q421136', 'display_name': 'Sorafenib', 'level': 3, 'score': 0.7039584}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.64547133}, {'id': 'https://openalex.org/C95190672', 'wikidata': 'https://www.wikidata.org/wiki/Q815382', 'display_name': 'Meta-analysis', 'level': 2, 'score': 0.51835996}, {'id': 'https://openalex.org/C2779984678', 'wikidata': 'https://www.wikidata.org/wiki/Q2145898', 'display_name': 'Response Evaluation Criteria in Solid Tumors', 'level': 4, 'score': 0.46086156}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.3507992}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.34392875}, {'id': 'https://openalex.org/C2776694085', 'wikidata': 'https://www.wikidata.org/wiki/Q974135', 'display_name': 'Chemotherapy', 'level': 2, 'score': 0.1701673}, {'id': 'https://openalex.org/C2778822529', 'wikidata': 'https://www.wikidata.org/wiki/Q1951525', 'display_name': 'Progressive disease', 'level': 3, 'score': 0.16307583}], 'mesh': [{'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D006528', 'descriptor_name': 'Carcinoma, Hepatocellular', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': True}, {'descriptor_ui': 'D016461', 'descriptor_name': 'Chemoembolization, Therapeutic', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D008113', 'descriptor_name': 'Liver Neoplasms', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': True}, {'descriptor_ui': 'D000077157', 'descriptor_name': 'Sorafenib', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D006528', 'descriptor_name': 'Carcinoma, Hepatocellular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006528', 'descriptor_name': 'Carcinoma, Hepatocellular', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D016461', 'descriptor_name': 'Chemoembolization, Therapeutic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003131', 'descriptor_name': 'Combined Modality Therapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018450', 'descriptor_name': 'Disease Progression', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008113', 'descriptor_name': 'Liver Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008113', 'descriptor_name': 'Liver Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077157', 'descriptor_name': 'Sorafenib', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D000077157', 'descriptor_name': 'Sorafenib', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077157', 'descriptor_name': 'Sorafenib', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/jjco/hyy138', 'pdf_url': 'https://academic.oup.com/jjco/article-pdf/48/12/1058/26751318/hyy138.pdf', 'source': {'id': 'https://openalex.org/S149902429', 'display_name': 'Japanese Journal of Clinical Oncology', 'issn_l': '0368-2811', 'issn': ['0368-2811', '1465-3621'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/30272196', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/jjco/hyy138', 'pdf_url': 'https://academic.oup.com/jjco/article-pdf/48/12/1058/26751318/hyy138.pdf', 'source': {'id': 'https://openalex.org/S149902429', 'display_name': 'Japanese Journal of Clinical Oncology', 'issn_l': '0368-2811', 'issn': ['0368-2811', '1465-3621'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.71, 'display_name': 'Good health and well-being'}], 'grants': [{'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81502026'}, {'funder': 'https://openalex.org/F4320338464', 'funder_display_name': 'Natural Science Foundation of Zhejiang Province', 'award_id': 'LQ16H180002'}, {'funder': 'https://openalex.org/F4320338464', 'funder_display_name': 'Natural Science Foundation of Zhejiang Province', 'award_id': 'LY18H160026'}], 'datasets': [], 'versions': [], 'referenced_works_count': 45, 'referenced_works': ['https://openalex.org/W1601002325', 'https://openalex.org/W1971837077', 'https://openalex.org/W1975154077', 'https://openalex.org/W1990095055', 'https://openalex.org/W1994193851', 'https://openalex.org/W1996229105', 'https://openalex.org/W2000307707', 'https://openalex.org/W2007872832', 'https://openalex.org/W2007920662', 'https://openalex.org/W2019634979', 'https://openalex.org/W2022454793', 'https://openalex.org/W2025152609', 'https://openalex.org/W2028319026', 'https://openalex.org/W2049811920', 'https://openalex.org/W2057378223', 'https://openalex.org/W2080219242', 'https://openalex.org/W2083256952', 'https://openalex.org/W2099734862', 'https://openalex.org/W2112716777', 'https://openalex.org/W2116475791', 'https://openalex.org/W2142806941', 'https://openalex.org/W2143045445', 'https://openalex.org/W2156410597', 'https://openalex.org/W2157823046', 'https://openalex.org/W2162741760', 'https://openalex.org/W2163945848', 'https://openalex.org/W2165951066', 'https://openalex.org/W2176045506', 'https://openalex.org/W2277004004', 'https://openalex.org/W2286222994', 'https://openalex.org/W2296475742', 'https://openalex.org/W23438228', 'https://openalex.org/W2470136591', 'https://openalex.org/W2507525933', 'https://openalex.org/W2528789218', 'https://openalex.org/W2583711744', 'https://openalex.org/W2661307008', 'https://openalex.org/W2739274500', 'https://openalex.org/W2767490296', 'https://openalex.org/W2790776429', 'https://openalex.org/W2917837889', 'https://openalex.org/W3139763557', 'https://openalex.org/W4211105405', 'https://openalex.org/W4239761639', 'https://openalex.org/W4245403358'], 'related_works': ['https://openalex.org/W4379336131', 'https://openalex.org/W4323536446', 'https://openalex.org/W2957827266', 'https://openalex.org/W2894284291', 'https://openalex.org/W2889691785', 'https://openalex.org/W2754556903', 'https://openalex.org/W2410776349', 'https://openalex.org/W2082648967', 'https://openalex.org/W1972665675', 'https://openalex.org/W1900595920'], 'abstract_inverted_index': {'The': [0, 91, 228], 'effectiveness': [1], 'of': [2, 5, 172, 230, 238], 'combination': [3, 81, 92, 155, 229], 'therapy': [4, 82, 93, 156], 'transarterial': [6, 33, 38, 55, 60, 231, 244], 'chemoembolization': [7, 34, 56, 61, 245], 'and': [8, 25, 37, 59, 84, 109, 219, 233], 'sorafenib': [9, 36, 58, 234], 'for': [10, 41, 63], 'unresectable': [11, 64, 239], 'hepatocellular': [12, 42, 65, 240], 'carcinoma': [13, 66, 241], 'are': [14], 'controversial': [15], 'in': [16, 80, 86, 122, 127, 248], 'some': [17], 'studies.': [18, 52], 'This': [19], 'meta-analysis': [20], 'aims': [21], 'to': [22, 49, 97, 140], 'compare': [23], 'efficacy': [24], 'safety,': [26], 'as': [27, 29], 'well': [28], 'regional': [30], 'disparities,': [31], 'between': [32], 'plus': [35, 57], 'chemotherapy': [39], 'alone': [40, 62], 'carcinoma.': [43], 'We': [44], 'systematically': [45], 'searched': [46], 'multiple': [47], 'databases': [48], 'select': [50], 'eligible': [51], 'Studies': [53], 'comparing': [54], 'were': [67, 89], 'included.': [68], 'Thirteen': [69], 'studies': [70], 'including': [71, 175], 'five': [72], 'randomized': [73], 'clinical': [74], 'trials': [75], 'with': [76, 243], '2538': [77], 'patients': [78], '(1121': [79], 'group': [83], '1417': [85], 'monotherapy': [87], 'group)': [88], 'selected.': [90], 'significantly': [94, 235], 'improved': [95], 'time': [96, 139], 'progression': [98], '(hazard': [99, 112, 157], 'ratio': [100, 113, 133, 143, 158, 180, 189, 197, 205, 213, 222], '0.66;': [101], '95%': [102, 115, 135, 145, 160, 182, 191, 199, 207, 215, 224], 'confidence': [103, 116, 136, 146, 161, 183, 192, 200, 208, 216, 225], 'interval': [104, 117, 137, 147, 162, 184, 193, 201, 209, 217, 226], '0.48–0.89;': [105], 'P': [106, 119, 164], '=': [107, 165], '0.006)': [108], 'overall': [110], 'survival': [111], '0.57;': [114], '0.45–0.72;': [118], '<': [120], '0.001)': [121], 'Asian': [123, 249], 'region': [124], 'but': [125], 'not': [126], 'non-Asian': [128], 'countries': [129], '(overall': [130], 'survival:': [131], 'hazard': [132, 142], '0.96,': [134], '0.73–1.20;': [138], 'progression:': [141], '1.08,': [144], '0.73–1.60).': [148], 'Additionally,': [149], 'disease': [150], 'control': [151], 'rate': [152], 'also': [153], 'favored': [154], '1.30;': [159], '1.00–1.69;': [163], '0.05),': [166], 'which': [167], 'simultaneously': [168], 'caused': [169], 'higher': [170], 'incidences': [171], 'adverse': [173], 'events,': [174], 'hand–foot': [176], 'skin': [177], 'reaction': [178], '(relative': [179, 188, 196, 204, 212, 221], '7.03;': [181], '4.77–10.37),': [185], 'hematological': [186], 'events': [187], '3.14;': [190], '0.99–10.01),': [194], 'diarrhea': [195], '2.75;': [198], '1.74–4.35),': [202], 'hypertension': [203], '2.58;': [206], '1.33–4.99),': [210], 'rash': [211], '2.87;': [214], '1.86–4.43)': [218], 'alopecia': [220], '4.88;': [223], '1.67–14.13).': [227], 'chemoembolizaiton': [232], 'improves': [236], 'outcomes': [237], 'compared': [242], 'monotherapy,': [246], 'especially': [247], 'region.': [250]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2894284291', 'counts_by_year': [{'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 1}], 'updated_date': '2024-12-07T19:45:12.289677', 'created_date': '2018-10-05'}