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'https://openalex.org/W2068477286', 'https://openalex.org/W2029356158', 'https://openalex.org/W2003605608', 'https://openalex.org/W1979875535'], 'abstract_inverted_index': {'症例は70歳代女性.自覚症状は特になかった.近医にて甲状腺腫大を指摘され当科紹介.頸部エコーで甲状腺右葉下極に1.3': [0], 'cm大,形状不整,辺縁粗雑,内部不均一,石灰化を伴う腫瘤を認めた.computed': [1], 'tomography': [2, 6], '(CT)': [3], 'で病変は胸骨甲状筋への浸潤が疑われ,両側頸部リンパ節腫大を認めたが,positron': [4], 'emission': [5], '(PET)-CTでは転移を疑う異常集積を認めなかった.細胞診では不整な濃染性核を有する異型上皮の大小の重積性あるいは乳頭状集塊を認め,乳頭癌が疑われた.以上,甲状腺乳頭癌の術前診断に対して甲状腺亜全摘と両側頸部中央区域リンパ節郭清を施行した.術後病理診断では胸骨甲状筋と右下副甲状腺への浸潤を伴う線維化の強い腫瘍が胞巣状に増生しており,核化傾向を伴っていたため扁平上皮癌が疑われ,また胞巣の一部に粘液を含んだ管腔構造を認め,粘表皮癌も疑われた.免疫染色ではcluster': [7], 'of': [8], 'differentiation': [9], '5': [10], '(CD5)': [11], '(+),tumor': [12], 'protein': [13], 'p63': [14], '(p63)': [15], '(+),KIT': [16], 'proto-oncogene': [17], 'receptor': [18], 'tyrosine': [19], 'kinase': [20], '(c-KIT': [21], '(CD117))': [22], '(+),thyroglobulin': [23], '(−),thyroid': [24], 'transcription': [25], 'factor-1': [26], '(TTF-1)': [27], '(−)': [28], 'であったことから胸腺様分化を示す癌(carcinoma': [29], 'showing': [30], 'thymus-like': [31], 'differentiation:': [32], 'CASTLE)の診断となった.CASTLEは組織学的に胸腺上皮腫瘍に類似した甲状腺癌である.多くのCASTLEの症例では未分化癌,低分化癌,扁平上皮癌と鑑別を要した.本症例も': [33], 'Hematoxylin-Eosin染色での検鏡では扁平上皮癌または粘表皮癌疑いであり,CD5を含む免疫染色を追加,診断が確定した.リンパ節転移や甲状腺外への浸潤は予後不良因子とされており,本症例でも今後,経過観察の継続が重要である.': [34]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2891009572', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}], 'updated_date': '2024-09-14T17:03:00.833843', 'created_date': '2018-09-27'}