Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2890184645', 'doi': 'https://doi.org/10.1093/neuonc/noy139.152', 'title': 'P01.110 Elderly patients >65years of age with newly diagnosed Glioblastoma multiforme gain life time from treatment with Tumor Treating Fields and Temozolomide', 'display_name': 'P01.110 Elderly patients >65years of age with newly diagnosed Glioblastoma multiforme gain life time from treatment with Tumor Treating Fields and Temozolomide', 'publication_year': 2018, 'publication_date': '2018-09-01', 'ids': {'openalex': 'https://openalex.org/W2890184645', 'doi': 'https://doi.org/10.1093/neuonc/noy139.152', 'mag': '2890184645'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/neuonc/noy139.152', 'pdf_url': 'https://academic.oup.com/neuro-oncology/article-pdf/20/suppl_3/iii256/25792910/noy139.152.pdf', 'source': {'id': 'https://openalex.org/S106908163', 'display_name': 'Neuro-Oncology', 'issn_l': '1522-8517', 'issn': ['1522-8517', '1523-5866'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://academic.oup.com/neuro-oncology/article-pdf/20/suppl_3/iii256/25792910/noy139.152.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5085357003', 'display_name': 'Gregory F. Guzauskas', 'orcid': 'https://orcid.org/0000-0002-9095-1672'}, 'institutions': [{'id': 'https://openalex.org/I201448701', 'display_name': 'University of Washington', 'ror': 'https://ror.org/00cvxb145', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I201448701']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'G F Guzauskas', 'raw_affiliation_strings': ['University of Washington Department of Pharmacy, Seattle, WA, United States'], 'affiliations': [{'raw_affiliation_string': 'University of Washington Department of Pharmacy, Seattle, WA, United States', 'institution_ids': ['https://openalex.org/I201448701']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5054151747', 'display_name': 'B C M Wang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I201448701', 'display_name': 'University of Washington', 'ror': 'https://ror.org/00cvxb145', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I201448701']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'B C M Wang', 'raw_affiliation_strings': ['University of Washington Department of Pharmacy, Seattle, WA, United States'], 'affiliations': [{'raw_affiliation_string': 'University of Washington Department of Pharmacy, Seattle, WA, United States', 'institution_ids': ['https://openalex.org/I201448701']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091378683', 'display_name': 'Adrian Kinzel', 'orcid': None}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'A Kinzel', 'raw_affiliation_strings': ['Novocure, Munich, Germany'], 'affiliations': [{'raw_affiliation_string': 'Novocure, Munich, Germany', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5053372870', 'display_name': 'Christina Proescholdt', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210107308', 'display_name': 'Novo Nordisk (Switzerland)', 'ror': 'https://ror.org/01p1t0k52', 'country_code': 'CH', 'type': 'company', 'lineage': ['https://openalex.org/I189090001', 'https://openalex.org/I2801134892', 'https://openalex.org/I4210107308', 'https://openalex.org/I4210159963']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'C Proescholdt', 'raw_affiliation_strings': ['Novocure, Root, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Novocure, Root, Switzerland', 'institution_ids': ['https://openalex.org/I4210107308']}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4612, 'currency': 'USD', 'value_usd': 4612, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 62}, 'biblio': {'volume': '20', 'issue': 'suppl_3', 'first_page': 'iii256', 'last_page': 'iii257'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10129', 'display_name': 'Glioma Diagnosis and Treatment', 'score': 0.7949, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10129', 'display_name': 'Glioma Diagnosis and Treatment', 'score': 0.7949, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/temozolomide', 'display_name': 'Temozolomide', 'score': 0.9154011}, {'id': 'https://openalex.org/keywords/subgroup-analysis', 'display_name': 'Subgroup analysis', 'score': 0.64996904}, {'id': 'https://openalex.org/keywords/post-hoc-analysis', 'display_name': 'Post-hoc analysis', 'score': 0.5491703}], 'concepts': [{'id': 'https://openalex.org/C2777389519', 'wikidata': 'https://www.wikidata.org/wiki/Q425088', 'display_name': 'Temozolomide', 'level': 3, 'score': 0.9154011}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8176042}, {'id': 'https://openalex.org/C187960798', 'wikidata': 'https://www.wikidata.org/wiki/Q7631152', 'display_name': 'Subgroup analysis', 'level': 3, 'score': 0.64996904}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.60929465}, {'id': 'https://openalex.org/C2776194525', 'wikidata': 'https://www.wikidata.org/wiki/Q282142', 'display_name': 'Glioblastoma', 'level': 2, 'score': 0.60341847}, {'id': 'https://openalex.org/C10515644', 'wikidata': 'https://www.wikidata.org/wiki/Q543310', 'display_name': 'Survival analysis', 'level': 2, 'score': 0.5810445}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.5711601}, {'id': 'https://openalex.org/C67761136', 'wikidata': 'https://www.wikidata.org/wiki/Q2105849', 'display_name': 'Post-hoc analysis', 'level': 2, 'score': 0.5491703}, {'id': 'https://openalex.org/C535046627', 'wikidata': 'https://www.wikidata.org/wiki/Q30612', 'display_name': 'Clinical trial', 'level': 2, 'score': 0.5376313}, {'id': 'https://openalex.org/C2776283816', 'wikidata': 'https://www.wikidata.org/wiki/Q332823', 'display_name': 'Survival rate', 'level': 2, 'score': 0.5307479}, {'id': 'https://openalex.org/C50382708', 'wikidata': 'https://www.wikidata.org/wiki/Q223218', 'display_name': 'Proportional hazards model', 'level': 2, 'score': 0.41070157}, {'id': 'https://openalex.org/C509974204', 'wikidata': 'https://www.wikidata.org/wiki/Q180507', 'display_name': 'Radiation therapy', 'level': 2, 'score': 0.33298707}, {'id': 'https://openalex.org/C95190672', 'wikidata': 'https://www.wikidata.org/wiki/Q815382', 'display_name': 'Meta-analysis', 'level': 2, 'score': 0.0863297}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/neuonc/noy139.152', 'pdf_url': 'https://academic.oup.com/neuro-oncology/article-pdf/20/suppl_3/iii256/25792910/noy139.152.pdf', 'source': {'id': 'https://openalex.org/S106908163', 'display_name': 'Neuro-Oncology', 'issn_l': '1522-8517', 'issn': ['1522-8517', '1523-5866'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144654', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/neuonc/noy139.152', 'pdf_url': 'https://academic.oup.com/neuro-oncology/article-pdf/20/suppl_3/iii256/25792910/noy139.152.pdf', 'source': {'id': 'https://openalex.org/S106908163', 'display_name': 'Neuro-Oncology', 'issn_l': '1522-8517', 'issn': ['1522-8517', '1523-5866'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/2', 'display_name': 'Zero hunger', 'score': 0.79}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W606085651', 'https://openalex.org/W3174247396', 'https://openalex.org/W3139389455', 'https://openalex.org/W3029609210', 'https://openalex.org/W2951968252', 'https://openalex.org/W2890184645', 'https://openalex.org/W2809156106', 'https://openalex.org/W2808769567', 'https://openalex.org/W2075981241', 'https://openalex.org/W2051372910'], 'abstract_inverted_index': {'Glioblastoma': [0], '(GBM)': [1], 'is': [2, 223], 'the': [3, 17, 52, 58, 90, 105, 113, 150, 154, 166, 210, 218, 238, 244, 258, 273, 277, 291, 298], 'most': [4], 'aggressive': [5], 'form': [6], 'of': [7, 51, 75, 104, 131, 149, 156, 165, 182, 199, 209, 240, 243, 257, 262, 276, 294], 'primary': [8], 'brain': [9], 'cancer': [10], 'in': [11, 32, 64, 89, 135, 196, 231, 253, 297, 312], 'adults.': [12], 'The': [13], 'EF-14': [14, 56, 114, 245, 299], 'trial': [15, 21, 167, 300], 'was': [16, 98, 138], 'first': [18], 'randomized': [19], 'controlled': [20], 'to': [22, 86, 161, 186, 267, 307], 'report': [23], 'a': [24, 35, 38, 71, 129, 197, 254, 280], 'survival': [25, 39, 60, 72, 96, 124, 134, 159, 181, 216, 222, 261], 'benefit': [26], 'for': [27, 77, 189, 203, 214, 284, 309], 'newly': [28, 313], 'diagnosed': [29, 314], 'GBM': [30, 110, 121, 315], 'patients': [31, 78, 111, 170, 190, 242, 278, 316], 'more': [33], 'than': [34, 42], 'decade': [36], 'with': [37, 80, 116, 172, 192, 248, 269, 279, 290], 'rate': [40, 130, 213], 'greater': [41], '10%': [43], 'at': [44, 73, 128], '5-years.': [45], 'A': [46], 'post': [47], 'hoc': [48], 'subgroup': [49, 66, 106, 239], 'analysis': [50], 'elderly': [53, 241], '(>65': [54], 'years)': [55], 'populationshowed': [57], 'greatest': [59], 'beneft': [61], 'from': [62, 112], 'TTFields': [63, 81, 173, 204, 249, 310], 'this': [65], '(HR': [67], '=': [68], '0.51)': [69], 'and': [70, 82, 152, 174, 319], '5-years': [74], '15%': [76], 'treated': [79, 171, 191], 'maintenance': [83], 'TMZ': [84, 91, 175, 193, 251, 270], 'compared': [85, 153, 185, 266], 'no': [87], 'survivors': [88], 'alone': [92], 'arm.': [93], 'An': [94], 'integrated': [95, 158], 'model': [97, 160], 'calculated,': [99], 'incorporating': [100], 'Kaplan': [101], 'Meier': [102], 'Data': [103], 'over': [107], '65': [108, 317], 'years': [109, 137, 184, 188, 202, 228, 235, 265, 318], 'Trial': [115, 246], 'epidemiological': [117], 'data': [118], 'on': [119], 'long-term': [120, 285], 'survival.': [122, 286], 'Future': [123], 'benefits': [125], 'were': [126], 'discounted': [127], '3%': [132, 141, 211], '(i.e.,': [133], 'future': [136, 215], 'reduced': [139], 'by': [140], 'per': [142], 'year).': [143], 'We': [144], 'also': [145], 'perfomed': [146], 'sensitivity': [147], 'analyses': [148], 'results': [151, 155, 288], 'our': [157], 'regression': [162], 'based': [163], 'extrapolations': [164], 'data.': [168], 'Elderly': [169], 'achieved': [176], 'an': [177], 'undiscounted': [178], 'mean': [179, 259], 'lifetime': [180, 260], '3.66': [183], '1.32': [187], 'alone,': [194, 271], 'resulting': [195, 219], 'gain': [198], '2.34': [200], 'life': [201, 220, 227, 234, 264], 'plus': [205, 250], 'TMZ.': [206], 'After': [207], 'application': [208], 'discount': [212], 'benefits,': [217], 'time': [221], '3.04': [224], 'vs.': [225], '1.29': [226], 'respectively,': [229], 'resuling': [230], '1.75': [232], 'incremental': [233], 'gained.': [236], 'In': [237], 'treatment': [247, 268, 311], 'resulted': [252], 'substantial': [255], 'increase': [256], '1,75': [263], 'despite': [272], 'older': [274], 'age': [275], 'naturally': [281], 'lower': [282], 'potential': [283], 'These': [287], 'together': [289], 'low': [292], 'incidence': [293], 'adverse': [295], 'events': [296], 'indicate': [301], 'that': [302], 'it': [303], 'may': [304], 'be': [305], 'appropriate': [306], 'opt': [308], 'older.': [320]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2890184645', 'counts_by_year': [], 'updated_date': '2024-12-13T09:16:12.737012', 'created_date': '2018-09-27'}