Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2888209731', 'doi': 'https://doi.org/10.1016/j.mimet.2018.08.008', 'title': 'The EDTA-based disk-combination tests are unreliable for the detection of MCR-mediated colistin-resistance in Enterobacteriaceae', 'display_name': 'The EDTA-based disk-combination tests are unreliable for the detection of MCR-mediated colistin-resistance in Enterobacteriaceae', 'publication_year': 2018, 'publication_date': '2018-08-20', 'ids': {'openalex': 'https://openalex.org/W2888209731', 'doi': 'https://doi.org/10.1016/j.mimet.2018.08.008', 'mag': '2888209731', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/30138643'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.mimet.2018.08.008', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S24124513', 'display_name': 'Journal of Microbiological Methods', 'issn_l': '0167-7012', 'issn': ['0167-7012', '1872-8359'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://boris.unibe.ch/119489/1/Accepted-1-s2.0-S0167701218305062-main.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5017497703', 'display_name': 'Mathieu Clément', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I118564535', 'display_name': 'University of Bern', 'ror': 'https://ror.org/02k7v4d05', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I118564535']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Mathieu Clément', 'raw_affiliation_strings': ['Graduate School of Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland', 'Institute for Infectious Diseases, University of Bern, Bern, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Institute for Infectious Diseases, University of Bern, Bern, Switzerland', 'institution_ids': ['https://openalex.org/I118564535']}, {'raw_affiliation_string': 'Graduate School of Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland', 'institution_ids': ['https://openalex.org/I118564535']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5014249018', 'display_name': 'Thomas Büdel', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I118564535', 'display_name': 'University of Bern', 'ror': 'https://ror.org/02k7v4d05', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I118564535']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Thomas Büdel', 'raw_affiliation_strings': ['Institute for Infectious Diseases, University of Bern, Bern, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Institute for Infectious Diseases, University of Bern, Bern, Switzerland', 'institution_ids': ['https://openalex.org/I118564535']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000535177', 'display_name': 'Odette J. Bernasconi', 'orcid': 'https://orcid.org/0000-0002-7579-5819'}, 'institutions': [{'id': 'https://openalex.org/I118564535', 'display_name': 'University of Bern', 'ror': 'https://ror.org/02k7v4d05', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I118564535']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Odette J. Bernasconi', 'raw_affiliation_strings': ['Graduate School of Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland', 'Institute for Infectious Diseases, University of Bern, Bern, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Graduate School of Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland', 'institution_ids': ['https://openalex.org/I118564535']}, {'raw_affiliation_string': 'Institute for Infectious Diseases, University of Bern, Bern, Switzerland', 'institution_ids': ['https://openalex.org/I118564535']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023667826', 'display_name': 'Luigi Principe', 'orcid': 'https://orcid.org/0000-0002-2000-5322'}, 'institutions': [{'id': 'https://openalex.org/I4210113373', 'display_name': 'Alessandro Manzoni Hospital', 'ror': 'https://ror.org/030kaa114', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210113373']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Luigi Principe', 'raw_affiliation_strings': ['Clinical Microbiology and Virology Unit, A. Manzoni Hospital, Lecco, Italy'], 'affiliations': [{'raw_affiliation_string': 'Clinical Microbiology and Virology Unit, A. Manzoni Hospital, Lecco, Italy', 'institution_ids': ['https://openalex.org/I4210113373']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063774580', 'display_name': 'Vincent Perreten', 'orcid': 'https://orcid.org/0000-0001-5722-9445'}, 'institutions': [{'id': 'https://openalex.org/I118564535', 'display_name': 'University of Bern', 'ror': 'https://ror.org/02k7v4d05', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I118564535']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Vincent Perreten', 'raw_affiliation_strings': ['Institute of Veterinary Bacteriology, University of Bern, Bern, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Institute of Veterinary Bacteriology, University of Bern, Bern, Switzerland', 'institution_ids': ['https://openalex.org/I118564535']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017156016', 'display_name': 'Francesco Luzzaro', 'orcid': 'https://orcid.org/0000-0002-8275-8389'}, 'institutions': [{'id': 'https://openalex.org/I4210113373', 'display_name': 'Alessandro Manzoni Hospital', 'ror': 'https://ror.org/030kaa114', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210113373']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Francesco Luzzaro', 'raw_affiliation_strings': ['Clinical Microbiology and Virology Unit, A. Manzoni Hospital, Lecco, Italy'], 'affiliations': [{'raw_affiliation_string': 'Clinical Microbiology and Virology Unit, A. Manzoni Hospital, Lecco, Italy', 'institution_ids': ['https://openalex.org/I4210113373']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5023022594', 'display_name': 'Andrea Endimiani', 'orcid': 'https://orcid.org/0000-0003-3186-5421'}, 'institutions': [{'id': 'https://openalex.org/I118564535', 'display_name': 'University of Bern', 'ror': 'https://ror.org/02k7v4d05', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I118564535']}], 'countries': ['CH'], 'is_corresponding': True, 'raw_author_name': 'Andrea Endimiani', 'raw_affiliation_strings': ['Institute for Infectious Diseases, University of Bern, Bern, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Institute for Infectious Diseases, University of Bern, Bern, Switzerland', 'institution_ids': ['https://openalex.org/I118564535']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5023022594'], 'corresponding_institution_ids': ['https://openalex.org/I118564535'], 'apc_list': {'value': 2850, 'currency': 'USD', 'value_usd': 2850, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.43, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 5, 'citation_normalized_percentile': {'value': 0.402728, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 79, 'max': 81}, 'biblio': {'volume': '153', 'issue': None, 'first_page': '31', 'last_page': '34'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10147', 'display_name': 'Global Challenge of Antibiotic Resistance in Bacteria', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1313', 'display_name': 'Molecular Medicine'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10147', 'display_name': 'Global Challenge of Antibiotic Resistance in Bacteria', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1313', 'display_name': 'Molecular Medicine'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11036', 'display_name': 'Pharmacokinetics of Antibiotics in Critically Ill Patients', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10654', 'display_name': 'Management and Epidemiology of Pneumonia', 'score': 0.997, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/colistin', 'display_name': 'Colistin', 'score': 0.8897095}, {'id': 'https://openalex.org/keywords/mcr-1', 'display_name': 'MCR-1', 'score': 0.67579824}, {'id': 'https://openalex.org/keywords/enterobacteriaceae-infections', 'display_name': 'Enterobacteriaceae Infections', 'score': 0.6018422}, {'id': 'https://openalex.org/keywords/multidrug-resistant-bacteria', 'display_name': 'Multidrug-Resistant Bacteria', 'score': 0.455993}], 'concepts': [{'id': 'https://openalex.org/C2779259085', 'wikidata': 'https://www.wikidata.org/wiki/Q418946', 'display_name': 'Colistin', 'level': 3, 'score': 0.8897095}, {'id': 'https://openalex.org/C2778910516', 'wikidata': 'https://www.wikidata.org/wiki/Q380136', 'display_name': 'Enterobacteriaceae', 'level': 4, 'score': 0.84144926}, {'id': 'https://openalex.org/C2777620836', 'wikidata': 'https://www.wikidata.org/wiki/Q23578725', 'display_name': 'MCR-1', 'level': 5, 'score': 0.67579824}, {'id': 'https://openalex.org/C2910948552', 'wikidata': 'https://www.wikidata.org/wiki/Q380136', 'display_name': 'Enterobacteriaceae Infections', 'level': 5, 'score': 0.6018422}, {'id': 'https://openalex.org/C2778660310', 'wikidata': 'https://www.wikidata.org/wiki/Q177998', 'display_name': 'Agar', 'level': 3, 'score': 0.591255}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.57305014}, {'id': 'https://openalex.org/C197404232', 'wikidata': 'https://www.wikidata.org/wiki/Q319827', 'display_name': 'Chelation', 'level': 2, 'score': 0.44370517}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.35939646}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.34575522}, {'id': 'https://openalex.org/C523546767', 'wikidata': 'https://www.wikidata.org/wiki/Q10876', 'display_name': 'Bacteria', 'level': 2, 'score': 0.26530105}, {'id': 'https://openalex.org/C547475151', 'wikidata': 'https://www.wikidata.org/wiki/Q25419', 'display_name': 'Escherichia coli', 'level': 3, 'score': 0.2429091}, {'id': 'https://openalex.org/C501593827', 'wikidata': 'https://www.wikidata.org/wiki/Q12187', 'display_name': 'Antibiotics', 'level': 2, 'score': 0.17995197}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.1242826}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.05039859}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D003091', 'descriptor_name': 'Colistin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D052978', 'descriptor_name': 'Disk Diffusion Antimicrobial Tests', 'qualifier_ui': 'Q000592', 'qualifier_name': 'standards', 'is_major_topic': True}, {'descriptor_ui': 'D024881', 'descriptor_name': 'Drug Resistance, Bacterial', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D004492', 'descriptor_name': 'Edetic Acid', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D004755', 'descriptor_name': 'Enterobacteriaceae', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003091', 'descriptor_name': 'Colistin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D052978', 'descriptor_name': 'Disk Diffusion Antimicrobial Tests', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D052978', 'descriptor_name': 'Disk Diffusion Antimicrobial Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004492', 'descriptor_name': 'Edetic Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004755', 'descriptor_name': 'Enterobacteriaceae', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D004755', 'descriptor_name': 'Enterobacteriaceae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008826', 'descriptor_name': 'Microbial Sensitivity Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015203', 'descriptor_name': 'Reproducibility of Results', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012680', 'descriptor_name': 'Sensitivity and Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.mimet.2018.08.008', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S24124513', 'display_name': 'Journal of Microbiological Methods', 'issn_l': '0167-7012', 'issn': ['0167-7012', '1872-8359'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://boris.unibe.ch/119489/', 'pdf_url': 'https://boris.unibe.ch/119489/1/Accepted-1-s2.0-S0167701218305062-main.pdf', 'source': {'id': 'https://openalex.org/S4306401086', 'display_name': 'Bern Open Repository and Information System (University of Bern)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I118564535', 'host_organization_name': 'University of Bern', 'host_organization_lineage': ['https://openalex.org/I118564535'], 'host_organization_lineage_names': ['University of Bern'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/30138643', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://boris.unibe.ch/119489/', 'pdf_url': 'https://boris.unibe.ch/119489/1/Accepted-1-s2.0-S0167701218305062-main.pdf', 'source': {'id': 'https://openalex.org/S4306401086', 'display_name': 'Bern Open Repository and Information System (University of Bern)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I118564535', 'host_organization_name': 'University of Bern', 'host_organization_lineage': ['https://openalex.org/I118564535'], 'host_organization_lineage_names': ['University of Bern'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320310993', 'funder_display_name': 'Hans-Sigrist-Stiftung', 'award_id': None}, {'funder': 'https://openalex.org/F4320320924', 'funder_display_name': 'Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung', 'award_id': '177378'}], 'datasets': [], 'versions': [], 'referenced_works_count': 27, 'referenced_works': ['https://openalex.org/W2062347073', 'https://openalex.org/W2102217986', 'https://openalex.org/W2342696571', 'https://openalex.org/W2343573713', 'https://openalex.org/W2444494164', 'https://openalex.org/W2504872050', 'https://openalex.org/W2570525150', 'https://openalex.org/W2593444269', 'https://openalex.org/W2605353609', 'https://openalex.org/W2622029395', 'https://openalex.org/W2622768456', 'https://openalex.org/W26641785', 'https://openalex.org/W2740287829', 'https://openalex.org/W2740527601', 'https://openalex.org/W2742292956', 'https://openalex.org/W2746873671', 'https://openalex.org/W2747942801', 'https://openalex.org/W2754815840', 'https://openalex.org/W2756986324', 'https://openalex.org/W2763659886', 'https://openalex.org/W2768815131', 'https://openalex.org/W2769205640', 'https://openalex.org/W2773164014', 'https://openalex.org/W2785542514', 'https://openalex.org/W2793959324', 'https://openalex.org/W2884130168', 'https://openalex.org/W2977386011'], 'related_works': ['https://openalex.org/W4282589990', 'https://openalex.org/W2992696714', 'https://openalex.org/W2898450640', 'https://openalex.org/W2895795892', 'https://openalex.org/W2885500619', 'https://openalex.org/W2796965525', 'https://openalex.org/W2756986324', 'https://openalex.org/W2740287829', 'https://openalex.org/W2499077378', 'https://openalex.org/W2288105368'], 'abstract_inverted_index': {'We': [0], 'evaluated': [1], 'several': [2], 'EDTA-based': [3], 'combined-disk': [4], 'tests': [5, 46], 'to': [6, 42], 'detect': [7], '25': [8], 'mcr': [9], 'producers': [10], 'among': [11], '48': [12], 'Enterobacteriaceae.': [13], 'Colistin': [14], 'disks': [15], 'plus': [16], 'EDTA': [17], '(292/584': [18], 'μg)': [19], 'on': [20], 'MH': [21], 'and': [22], 'CAMH': [23], 'agar': [24], 'were': [25, 28], 'used.': [26], 'Results': [27], 'positive': [29], 'if': [30], 'with': [31], 'chelator': [32], 'there': [33], 'was': [34], 'an': [35], 'inhibition': [36], 'zone': [37], 'increase': [38], '≥3': [39], 'mm': [40], 'compared': [41], 'colistin': [43], 'alone.': [44], 'All': [45], 'resulted': [47], 'unreliable': [48], '(sensitivity': [49], '≤68%).': [50]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2888209731', 'counts_by_year': [{'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 2}], 'updated_date': '2024-09-17T20:00:57.194993', 'created_date': '2018-08-31'}