Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2887931962', 'doi': 'https://doi.org/10.1210/er.2018-00139', 'title': 'The Expanding Spectrum of Primary Aldosteronism: Implications for Diagnosis, Pathogenesis, and Treatment', 'display_name': 'The Expanding Spectrum of Primary Aldosteronism: Implications for Diagnosis, Pathogenesis, and Treatment', 'publication_year': 2018, 'publication_date': '2018-08-15', 'ids': {'openalex': 'https://openalex.org/W2887931962', 'doi': 'https://doi.org/10.1210/er.2018-00139', 'mag': '2887931962', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/30124805', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6260247'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1210/er.2018-00139', 'pdf_url': 'https://academic.oup.com/edrv/article-pdf/39/6/1057/26660673/er.2018-00139.pdf', 'source': {'id': 'https://openalex.org/S13493133', 'display_name': 'Endocrine Reviews', 'issn_l': '0163-769X', 'issn': ['0163-769X', '1945-7189'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://academic.oup.com/edrv/article-pdf/39/6/1057/26660673/er.2018-00139.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5067976959', 'display_name': 'Anand Vaidya', 'orcid': 'https://orcid.org/0000-0002-0314-9252'}, 'institutions': [{'id': 'https://openalex.org/I1283280774', 'display_name': "Brigham and Women's Hospital", 'ror': 'https://ror.org/04b6nzv94', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1283280774', 'https://openalex.org/I48633490']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Anand Vaidya', 'raw_affiliation_strings': ['Center for Adrenal Disorders, Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts'], 'affiliations': [{'raw_affiliation_string': 'Center for Adrenal Disorders, Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts', 'institution_ids': ['https://openalex.org/I1283280774', 'https://openalex.org/I136199984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023647519', 'display_name': 'Paolo Mulatero', 'orcid': 'https://orcid.org/0000-0003-4913-3608'}, 'institutions': [{'id': 'https://openalex.org/I55143463', 'display_name': 'University of Turin', 'ror': 'https://ror.org/048tbm396', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I55143463']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Paolo Mulatero', 'raw_affiliation_strings': ['Division of Internal Medicine and Hypertension, Department of Medical Sciences, University of Torino, Torino, Italy'], 'affiliations': [{'raw_affiliation_string': 'Division of Internal Medicine and Hypertension, Department of Medical Sciences, University of Torino, Torino, Italy', 'institution_ids': ['https://openalex.org/I55143463']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5033678258', 'display_name': 'René Baudrand', 'orcid': 'https://orcid.org/0000-0002-8655-4957'}, 'institutions': [{'id': 'https://openalex.org/I162148367', 'display_name': 'Pontificia Universidad Católica de Chile', 'ror': 'https://ror.org/04teye511', 'country_code': 'CL', 'type': 'education', 'lineage': ['https://openalex.org/I162148367']}], 'countries': ['CL'], 'is_corresponding': False, 'raw_author_name': 'Rene Baudrand', 'raw_affiliation_strings': ['Program for Adrenal Disorders and Hypertension, Department of Endocrinology, Pontificia Universidad Catolica de Chile, Santiago, Chile'], 'affiliations': [{'raw_affiliation_string': 'Program for Adrenal Disorders and Hypertension, Department of Endocrinology, Pontificia Universidad Catolica de Chile, Santiago, Chile', 'institution_ids': ['https://openalex.org/I162148367']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5048806317', 'display_name': 'Gail K. Adler', 'orcid': 'https://orcid.org/0000-0003-3506-7347'}, 'institutions': [{'id': 'https://openalex.org/I1283280774', 'display_name': "Brigham and Women's Hospital", 'ror': 'https://ror.org/04b6nzv94', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1283280774', 'https://openalex.org/I48633490']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Gail K Adler', 'raw_affiliation_strings': ['Center for Adrenal Disorders, Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts'], 'affiliations': [{'raw_affiliation_string': 'Center for Adrenal Disorders, Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts', 'institution_ids': ['https://openalex.org/I1283280774', 'https://openalex.org/I136199984']}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5067976959'], 'corresponding_institution_ids': ['https://openalex.org/I1283280774', 'https://openalex.org/I136199984'], 'apc_list': {'value': 3400, 'currency': 'USD', 'value_usd': 3400, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.951, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 196, 'citation_normalized_percentile': {'value': 0.588055, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '39', 'issue': '6', 'first_page': '1057', 'last_page': '1088'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11839', 'display_name': 'Management of Primary Aldosteronism', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11839', 'display_name': 'Management of Primary Aldosteronism', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11054', 'display_name': 'Pheochromocytoma and Paraganglioma', 'score': 0.9968, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T14486', 'display_name': 'Role of Urotensin II in Cardiovascular Physiology and Disease', 'score': 0.989, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/primary-aldosteronism', 'display_name': 'Primary Aldosteronism', 'score': 0.651734}, {'id': 'https://openalex.org/keywords/aldosterone', 'display_name': 'Aldosterone', 'score': 0.5511}, {'id': 'https://openalex.org/keywords/hyperaldosteronism', 'display_name': 'Hyperaldosteronism', 'score': 0.5164654}, {'id': 'https://openalex.org/keywords/pathogenesis', 'display_name': 'Pathogenesis', 'score': 0.48446512}, {'id': 'https://openalex.org/keywords/secondary-hypertension', 'display_name': 'Secondary hypertension', 'score': 0.46531108}, {'id': 'https://openalex.org/keywords/essential-hypertension', 'display_name': 'Essential hypertension', 'score': 0.42182532}], 'concepts': [{'id': 'https://openalex.org/C2780233176', 'wikidata': 'https://www.wikidata.org/wiki/Q1939330', 'display_name': 'Primary aldosteronism', 'level': 3, 'score': 0.96308964}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7658311}, {'id': 'https://openalex.org/C2778242168', 'wikidata': 'https://www.wikidata.org/wiki/Q794086', 'display_name': 'Hypokalemia', 'level': 2, 'score': 0.5728294}, {'id': 'https://openalex.org/C2778525890', 'wikidata': 'https://www.wikidata.org/wiki/Q184564', 'display_name': 'Aldosterone', 'level': 2, 'score': 0.5583105}, {'id': 'https://openalex.org/C2776292634', 'wikidata': 'https://www.wikidata.org/wiki/Q1640860', 'display_name': 'Hyperaldosteronism', 'level': 3, 'score': 0.5164654}, {'id': 'https://openalex.org/C2780942790', 'wikidata': 'https://www.wikidata.org/wiki/Q372016', 'display_name': 'Pathogenesis', 'level': 2, 'score': 0.48446512}, {'id': 'https://openalex.org/C2777581072', 'wikidata': 'https://www.wikidata.org/wiki/Q987319', 'display_name': 'Secondary hypertension', 'level': 3, 'score': 0.46531108}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.43350738}, {'id': 'https://openalex.org/C2777097880', 'wikidata': 'https://www.wikidata.org/wiki/Q988405', 'display_name': 'Essential hypertension', 'level': 3, 'score': 0.42182532}, {'id': 'https://openalex.org/C189135053', 'wikidata': 'https://www.wikidata.org/wiki/Q3454531', 'display_name': 'Mineralocorticoid receptor', 'level': 3, 'score': 0.41912568}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.4123208}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.38373286}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.3332703}, {'id': 'https://openalex.org/C84393581', 'wikidata': 'https://www.wikidata.org/wiki/Q82642', 'display_name': 'Blood pressure', 'level': 2, 'score': 0.15356308}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.109598905}], 'mesh': [{'descriptor_ui': 'D006929', 'descriptor_name': 'Hyperaldosteronism', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006929', 'descriptor_name': 'Hyperaldosteronism', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D006929', 'descriptor_name': 'Hyperaldosteronism', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006929', 'descriptor_name': 'Hyperaldosteronism', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D006929', 'descriptor_name': 'Hyperaldosteronism', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1210/er.2018-00139', 'pdf_url': 'https://academic.oup.com/edrv/article-pdf/39/6/1057/26660673/er.2018-00139.pdf', 'source': {'id': 'https://openalex.org/S13493133', 'display_name': 'Endocrine Reviews', 'issn_l': '0163-769X', 'issn': ['0163-769X', '1945-7189'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc6260247', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260247', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/30124805', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1210/er.2018-00139', 'pdf_url': 'https://academic.oup.com/edrv/article-pdf/39/6/1057/26660673/er.2018-00139.pdf', 'source': {'id': 'https://openalex.org/S13493133', 'display_name': 'Endocrine Reviews', 'issn_l': '0163-769X', 'issn': ['0163-769X', '1945-7189'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.82}], 'grants': [{'funder': 'https://openalex.org/F4320332161', 'funder_display_name': 'National Institutes of Health', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 258, 'referenced_works': ['https://openalex.org/W125284107', 'https://openalex.org/W137431462', 'https://openalex.org/W1535399883', 'https://openalex.org/W1577094786', 'https://openalex.org/W1577679403', 'https://openalex.org/W1650509978', 'https://openalex.org/W1796196870', 'https://openalex.org/W1797367453', 'https://openalex.org/W1838763091', 'https://openalex.org/W1862205625', 'https://openalex.org/W1872613035', 'https://openalex.org/W1885172161', 'https://openalex.org/W1907427644', 'https://openalex.org/W1923553208', 'https://openalex.org/W195587408', 'https://openalex.org/W1963677664', 'https://openalex.org/W1964629239', 'https://openalex.org/W1967440935', 'https://openalex.org/W1968567987', 'https://openalex.org/W1969509483', 'https://openalex.org/W1970103235', 'https://openalex.org/W1972430810', 'https://openalex.org/W1975847524', 'https://openalex.org/W1977564735', 'https://openalex.org/W1979022882', 'https://openalex.org/W1979069430', 'https://openalex.org/W1979309614', 'https://openalex.org/W1980312558', 'https://openalex.org/W1983803713', 'https://openalex.org/W1985327924', 'https://openalex.org/W1988349432', 'https://openalex.org/W1990209083', 'https://openalex.org/W1990806018', 'https://openalex.org/W1991449126', 'https://openalex.org/W1992842298', 'https://openalex.org/W1993600102', 'https://openalex.org/W1995501138', 'https://openalex.org/W1997949373', 'https://openalex.org/W2001601001', 'https://openalex.org/W2002317491', 'https://openalex.org/W2003315040', 'https://openalex.org/W2003989747', 'https://openalex.org/W2004602029', 'https://openalex.org/W2007085386', 'https://openalex.org/W2008218942', 'https://openalex.org/W2008821347', 'https://openalex.org/W2012910138', 'https://openalex.org/W2014246045', 'https://openalex.org/W2018220023', 'https://openalex.org/W2019645953', 'https://openalex.org/W2019857800', 'https://openalex.org/W2022880162', 'https://openalex.org/W2024885055', 'https://openalex.org/W2025063380', 'https://openalex.org/W2027104468', 'https://openalex.org/W2027962635', 'https://openalex.org/W2028022705', 'https://openalex.org/W2028235817', 'https://openalex.org/W2028956013', 'https://openalex.org/W2032582841', 'https://openalex.org/W2036247250', 'https://openalex.org/W2036745719', 'https://openalex.org/W2037612479', 'https://openalex.org/W2040581237', 'https://openalex.org/W2040925848', 'https://openalex.org/W2041776437', 'https://openalex.org/W2043717590', 'https://openalex.org/W2048712799', 'https://openalex.org/W2050310843', 'https://openalex.org/W2052968067', 'https://openalex.org/W2057317313', 'https://openalex.org/W2057961394', 'https://openalex.org/W2059351949', 'https://openalex.org/W2061341378', 'https://openalex.org/W2061764902', 'https://openalex.org/W2063599459', 'https://openalex.org/W2067816291', 'https://openalex.org/W2071127848', 'https://openalex.org/W2071430881', 'https://openalex.org/W2075016374', 'https://openalex.org/W2076825380', 'https://openalex.org/W2077547488', 'https://openalex.org/W2077932410', 'https://openalex.org/W2078741210', 'https://openalex.org/W2081645613', 'https://openalex.org/W2082883792', 'https://openalex.org/W2083120105', 'https://openalex.org/W2087225685', 'https://openalex.org/W2087855842', 'https://openalex.org/W2089400376', 'https://openalex.org/W2089564914', 'https://openalex.org/W2092182177', 'https://openalex.org/W2093901402', 'https://openalex.org/W2096425398', 'https://openalex.org/W2096645292', 'https://openalex.org/W2098519186', 'https://openalex.org/W2098555647', 'https://openalex.org/W2099488003', 'https://openalex.org/W2099583783', 'https://openalex.org/W2103452905', 'https://openalex.org/W2104836122', 'https://openalex.org/W2107999636', 'https://openalex.org/W2110463898', 'https://openalex.org/W2110638183', 'https://openalex.org/W2111582520', 'https://openalex.org/W2113014870', 'https://openalex.org/W2113930277', 'https://openalex.org/W2114339665', 'https://openalex.org/W2114594866', 'https://openalex.org/W2116698088', 'https://openalex.org/W2117150574', 'https://openalex.org/W2117490534', 'https://openalex.org/W2120347052', 'https://openalex.org/W2121766756', 'https://openalex.org/W2122039587', 'https://openalex.org/W2122595081', 'https://openalex.org/W2123144543', 'https://openalex.org/W2123184974', 'https://openalex.org/W2124034732', 'https://openalex.org/W2124738746', 'https://openalex.org/W2126447127', 'https://openalex.org/W2127215552', 'https://openalex.org/W2128287943', 'https://openalex.org/W2129950671', 'https://openalex.org/W2132044241', 'https://openalex.org/W2136936562', 'https://openalex.org/W2141197851', 'https://openalex.org/W2141479541', 'https://openalex.org/W2141779514', 'https://openalex.org/W2143300626', 'https://openalex.org/W2144261534', 'https://openalex.org/W2145754425', 'https://openalex.org/W2147066085', 'https://openalex.org/W2147621031', 'https://openalex.org/W2150302805', 'https://openalex.org/W2151167240', 'https://openalex.org/W2152681812', 'https://openalex.org/W2154694043', 'https://openalex.org/W2154788287', 'https://openalex.org/W2156119953', 'https://openalex.org/W2156497356', 'https://openalex.org/W2156939318', 'https://openalex.org/W2157610967', 'https://openalex.org/W2157801554', 'https://openalex.org/W2159365812', 'https://openalex.org/W2160612644', 'https://openalex.org/W2161920873', 'https://openalex.org/W2163393793', 'https://openalex.org/W2163881723', 'https://openalex.org/W2164282511', 'https://openalex.org/W2166045505', 'https://openalex.org/W2168778005', 'https://openalex.org/W2168924012', 'https://openalex.org/W2169857190', 'https://openalex.org/W2171768326', 'https://openalex.org/W2178916197', 'https://openalex.org/W2180775593', 'https://openalex.org/W2188408455', 'https://openalex.org/W2193446858', 'https://openalex.org/W2216243113', 'https://openalex.org/W2224048827', 'https://openalex.org/W2231119533', 'https://openalex.org/W2233921369', 'https://openalex.org/W2266820106', 'https://openalex.org/W2269755209', 'https://openalex.org/W2273687839', 'https://openalex.org/W2290633895', 'https://openalex.org/W2312715796', 'https://openalex.org/W2318109202', 'https://openalex.org/W2320400149', 'https://openalex.org/W2323458614', 'https://openalex.org/W2328521507', 'https://openalex.org/W2328926651', 'https://openalex.org/W2329138927', 'https://openalex.org/W2339300299', 'https://openalex.org/W2341581017', 'https://openalex.org/W2429510502', 'https://openalex.org/W2460484699', 'https://openalex.org/W2465200336', 'https://openalex.org/W2473587640', 'https://openalex.org/W2484432461', 'https://openalex.org/W2500553549', 'https://openalex.org/W2504981678', 'https://openalex.org/W2507510102', 'https://openalex.org/W2514693695', 'https://openalex.org/W2515022149', 'https://openalex.org/W2519578718', 'https://openalex.org/W2522526745', 'https://openalex.org/W2522938965', 'https://openalex.org/W2528513517', 'https://openalex.org/W2549741543', 'https://openalex.org/W2549776302', 'https://openalex.org/W2552476657', 'https://openalex.org/W2557454322', 'https://openalex.org/W2573330445', 'https://openalex.org/W2582159637', 'https://openalex.org/W2587872553', 'https://openalex.org/W2595764720', 'https://openalex.org/W2600438012', 'https://openalex.org/W2604461124', 'https://openalex.org/W2604715325', 'https://openalex.org/W2605241743', 'https://openalex.org/W2605251296', 'https://openalex.org/W2606248084', 'https://openalex.org/W2606339763', 'https://openalex.org/W2606392225', 'https://openalex.org/W2610903647', 'https://openalex.org/W2611121922', 'https://openalex.org/W2613190330', 'https://openalex.org/W2613926670', 'https://openalex.org/W2617388174', 'https://openalex.org/W2618064573', 'https://openalex.org/W2618657196', 'https://openalex.org/W2624544718', 'https://openalex.org/W2741012772', 'https://openalex.org/W2743577687', 'https://openalex.org/W2748795020', 'https://openalex.org/W2760971233', 'https://openalex.org/W2762703482', 'https://openalex.org/W2765314468', 'https://openalex.org/W2766250829', 'https://openalex.org/W2766766263', 'https://openalex.org/W2767092533', 'https://openalex.org/W2767799851', 'https://openalex.org/W2768057265', 'https://openalex.org/W2770837559', 'https://openalex.org/W2771432457', 'https://openalex.org/W2772618307', 'https://openalex.org/W2772975884', 'https://openalex.org/W2774697273', 'https://openalex.org/W2776596297', 'https://openalex.org/W2784117724', 'https://openalex.org/W2789114977', 'https://openalex.org/W2790443436', 'https://openalex.org/W2791182539', 'https://openalex.org/W2792973160', 'https://openalex.org/W2793147627', 'https://openalex.org/W2793806343', 'https://openalex.org/W2793929830', 'https://openalex.org/W2794312234', 'https://openalex.org/W2796868581', 'https://openalex.org/W2799600787', 'https://openalex.org/W2801560374', 'https://openalex.org/W2801658748', 'https://openalex.org/W2804783428', 'https://openalex.org/W2852717346', 'https://openalex.org/W2864747507', 'https://openalex.org/W2884884048', 'https://openalex.org/W2887100951', 'https://openalex.org/W2890253902', 'https://openalex.org/W2895985163', 'https://openalex.org/W4210466116', 'https://openalex.org/W4234540174', 'https://openalex.org/W4234749653', 'https://openalex.org/W4252126843', 'https://openalex.org/W4317527875', 'https://openalex.org/W4366064100', 'https://openalex.org/W561187501'], 'related_works': ['https://openalex.org/W801193981', 'https://openalex.org/W4280628405', 'https://openalex.org/W3115090319', 'https://openalex.org/W2921097002', 'https://openalex.org/W2804602972', 'https://openalex.org/W2735261925', 'https://openalex.org/W2496231646', 'https://openalex.org/W2404305588', 'https://openalex.org/W2401847221', 'https://openalex.org/W2395273970'], 'abstract_inverted_index': {'Primary': [0], 'aldosteronism': [1, 23, 72, 100, 143, 186, 224], 'is': [2, 8, 101, 159], 'characterized': [3], 'by': [4, 26], 'aldosterone': [5, 115], 'secretion': [6, 116], 'that': [7, 33, 95, 108, 117, 150, 184, 199, 212, 240], 'independent': [9], 'of': [10, 21, 29, 39, 88, 98, 113, 141, 177, 192, 222, 250], 'renin': [11], 'and': [12, 15, 44, 55, 69, 77, 82, 107, 110, 156, 175, 225, 233], 'angiotensin': [13], 'II': [14], 'sodium': [16], 'status.': [17], 'The': [18], 'deleterious': [19], 'effects': [20], 'primary': [22, 71, 99, 142, 178, 185, 223, 251], 'are': [24], 'mediated': [25], 'excessive': [27], 'activation': [28], 'the': [30, 36, 51, 64, 84, 89, 96, 146, 151, 172, 220, 244, 248], 'mineralocorticoid': [31], 'receptor': [32], 'results': [34], 'in': [35], 'well-known': [37], 'consequences': [38], 'volume': [40], 'expansion,': [41], 'hypertension,': [42], 'hypokalemia,': [43], 'metabolic': [45], 'alkalosis,': [46], 'but': [47], 'it': [48], 'also': [49], 'increases': [50], 'risk': [52, 121, 153], 'for': [53, 154, 219], 'cardiovascular': [54, 120, 155, 202], 'kidney': [56, 157], 'disease,': [57], 'as': [58, 60], 'well': [59], 'death.': [61], 'For': [62], 'decades,': [63], 'approaches': [65, 148], 'to': [66, 128, 137, 170, 197, 214, 228], 'defining,': [67], 'diagnosing,': [68], 'treating': [70, 83], 'have': [73], 'been': [74], 'relatively': [75], 'constant': [76], 'generally': [78], 'focused': [79], 'on': [80], 'detecting': [81], 'more': [85], 'severe': [86], 'presentations': [87], 'disease.': [90], 'However,': [91], 'emerging': [92, 207], 'evidence': [93, 182, 208], 'suggests': [94], 'prevalence': [97], 'much': [102], 'greater': [103], 'than': [104], 'previously': [105], 'recognized,': [106], 'milder': [109], 'nonclassical': [111], 'forms': [112, 140], 'renin-independent': [114], 'impart': [118], 'heightened': [119], 'may': [122], 'be': [123], 'common.': [124], 'Public': [125], 'health': [126], 'efforts': [127], 'prevent': [129], 'aldosterone-mediated': [130], 'end-organ': [131], 'disease': [132, 158], 'will': [133], 'require': [134], 'improved': [135], 'capabilities': [136], 'diagnose': [138], 'all': [139], 'while': [144], 'optimizing': [145], 'treatment': [147, 176, 249], 'such': [149], 'excess': [152], 'adequately': [160], 'mitigated.': [161], 'In': [162], 'this': [163], 'review,': [164], 'we': [165, 205, 236], 'present': [166], 'a': [167, 189, 216, 226], 'physiologic': [168], 'approach': [169, 246], 'considering': [171], 'diagnosis,': [173], 'pathogenesis,': [174], 'aldosteronism.': [179, 252], 'We': [180], 'review': [181, 206, 237], 'suggesting': [183], 'manifests': [187], 'across': [188], 'wide': [190], 'spectrum': [191, 232], 'severity,': [193], 'ranging': [194], 'from': [195, 209], 'mild': [196], 'overt,': [198], 'correlates': [200], 'with': [201], 'risk.': [203], 'Furthermore,': [204], 'genetic': [210], 'studies': [211, 239], 'begin': [213], 'provide': [215, 241], 'theoretical': [217], 'explanation': [218], 'pathogenesis': [221], 'link': [227], 'its': [229], 'phenotypic': [230], 'severity': [231], 'prevalence.': [234], 'Finally,': [235], 'human': [238], 'insights': [242], 'into': [243], 'optimal': [245], 'toward': [247]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2887931962', 'counts_by_year': [{'year': 2024, 'cited_by_count': 26}, {'year': 2023, 'cited_by_count': 35}, {'year': 2022, 'cited_by_count': 45}, {'year': 2021, 'cited_by_count': 45}, {'year': 2020, 'cited_by_count': 26}, {'year': 2019, 'cited_by_count': 14}, {'year': 2017, 'cited_by_count': 1}], 'updated_date': '2024-09-18T23:10:22.667851', 'created_date': '2018-08-22'}