Title: Comparison of Sevoflurane and Propofol with Fentanyl for Tracheal Intubation Without Muscle Relaxant
Abstract: SUMMARY:
Comparing the effectiveness of sevoflurane and propofol with fentanyl for tracheal intubation without muscle Relaxant in our study we summarize:
• Optimal intubating conditions were better in sevoflurane – fentanyl (92.5%) combination than propofol – fentanyl (52.5%) combination.(P – 0.0001).
• Acceptable (optimal or good) intubating conditions was best with sevoflurane – fentanyl (100%) combination than propofol – fentanyl (82.5%) combination. (P – 0.011).
• Cough after intubation and cuff inflation was least in sevoflurane group than in propofol group. (90% vs 62.5%) – P = 0.026 ; (97.5% vs 77.5%) – P = 0.013.
• Apnea was more pronounced with propofol group (100%) than with sevoflurane group (12.5%) (P – 0.0001).
• There was significant reduction in the mean arterial pressure 1 min and 5 minutes after intubation compared with baseline but the mean arterial pressure was well maintained above 70 mm Hg.
• There was no difference in the heart rate,systolic and diastolic blood pressure between the 2 groups.
CONCLUSION:
In conclusion, anaesthetic induction and tracheal intubation without muscle relaxants in premedicated healthy adult patients undergoing elective surgery is better achieved by incremental induction of sevoflurane and fentanyl 2 μg/kg than with propofol 3 mg/kg and fentanyl 2 μg/kg. The intubating conditions were better with sevoflurane – fentanyl – lidocaine combination than propofol –fentanyl - lidocaine. Hemodynamic changes were similar in both the groups.
Publication Year: 2013
Publication Date: 2013-04-01
Language: en
Type: dissertation
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