Publication Information

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18, 95, 323], 'a': [6, 96, 100, 324], 'major': [7], 'global': [8], 'public': [9], 'health': [10], 'problem.': [11], 'Early': [12], 'diagnosis': [13], 'of': [14, 24, 40, 64, 77, 114, 145, 207, 226, 256, 265, 285, 290, 296, 313], 'drug-resistant': [15, 41], '(TB)': [17], 'essential': [19], 'for': [20, 38, 73, 99, 111, 183, 241, 293, 329], 'minimizing': [21], 'the': [22, 53, 65, 74, 112, 155, 166, 173, 179, 194, 208, 223, 237, 257, 266, 273, 294, 314], 'risk': [23], 'Mycobacterium': [25], '(MTB)': [27], 'transmission.': [28], 'The': [29, 143, 160, 229, 288, 311], 'conventional': [30, 167], 'culture': [31], 'based': [32], 'drug': [33, 168, 333], 'susceptibility': [34, 169], 'testing': [35, 170], '(DST)': [36], 'methods': [37], 'detection': [39, 76, 113, 295], 'M.': [42], 'are': [44], 'laborious': [45], 'and': [46, 84, 123, 141, 252, 302, 308, 326, 331], 'time': [47], 'consuming.': [48], 'Pyrosequencing': [49], '(PSQ)': [50], 'assay': [51, 72, 292, 316, 322], 'has': [52], 'ability': [54], 'to': [55, 62, 79, 190, 214, 243, 249, 298], 'rapidly': [56], 'detect': [57], 'multiple': [58], 'mutations': [59, 115, 221, 280, 335], 'conferring': [60], 'resistance': [61, 78, 242, 297, 334], 'many': [63], 'anti-tuberculosis': [66], 'drugs.': [67], '\r\nOBJECTIVES': [68], ':\r\nTo': [69], 'evaluate': [70], 'PSQ': [71, 128, 161, 193, 291, 315, 321], 'rapid': [75, 325], 'Rifampicin': [80], '(RIF)': [81], 'Fluoroquinolones': [82], '(FQ)': [83], 'Aminoglycosides': [85], 'in': [86, 104, 116, 172, 199, 222, 272, 282], 'MTB': [87, 106, 133, 337], 'clinical': [88, 107, 134, 338], 'isolates': [89, 108, 135, 181, 210, 219, 239, 259, 268], '\r\nMATERIALS': [90], 'AND': [91, 176], 'METHODS': [92], '\r\nThis': [94], 'prospective': [97], 'study': [98], 'period': [101], '1.5': [102], 'years': [103], 'which': [105], 'were': [109, 163, 187, 211, 246], 'evaluated': [110, 277], 'rpoB': [117, 200], 'gene': [118, 121, 125, 201, 275], '(rifampicin),': [119], 'gyrA': [120, 227], '(fluoroquinolones),': [122], 'rrs': [124, 274, 286], '(aminoglycosides)': [126], 'by': [127, 152], 'assay.': [129], 'DNA': [130], 'extraction': [131], 'from': [132, 336], 'was': [136, 149, 202, 233, 304, 317], 'performed': [137], 'using': [138, 154], 'Tris-HCl': [139], 'buffer': [140], 'chloroform.': [142], 'amplification': [144], 'respective': [146], 'target': [147], 'genes': [148], 'done': [150, 171], 'followed': [151], 'sequencing': [153], 'PyroMark': [156], 'Q24': [157], 'ID': [158], 'system.': [159], 'results': [162], 'compared': [164], 'with': [165], 'laboratory.': [174], '\r\nRESULTS': [175], 'DISCUSSION': [177], ':\r\nOf': [178], '57': [180], 'tested': [182, 240], 'RIF': [184], 'resistance,': [185], '40': [186], 'phenotypically': [188, 212, 247], 'Rifampicin.': [191], 'By': [192], 'most': [195], 'predominant': [196, 230], 'mutation': [197, 231, 271], 'observed': [198, 232], 'TCG531TTG': [203], '(82%).': [204], 'Twenty': [205], 'eight': [206], '50': [209], 'FQ.': [215], 'Of': [216, 236], 'these,': [217], '20': [218], 'showed': [220], '94th': [224], 'codon': [225], 'gene.': [228, 287], 'GAC94GGC': [234], '(55%).': [235], '51': [238], 'aminoglycosides': [244], '10': [245, 258], 'Capreomycin': [250], '(CAP)': [251], 'Kanamycin': [253], '(KAN).': [254], 'Five': [255], 'had': [260, 269], 'A1401G': [261], 'mutation.': [262], 'However,': [263], '4': [264], 'no': [270], 'segments': [276], 'suggesting': [278], 'that': [279], 'exist': [281], 'other': [283], 'sites': [284], 'sensitivity': [289], 'RIF,': [299], 'FQ,': [300], 'CAP': [301], 'KAN': [303], '100%,': [305, 306], '40%': [307], '50%': [309], 'respectively.': [310], 'specificity': [312], '100%.': [318], '\r\nCONCLUSION': [319], ':\r\nThe': [320], 'effective': [327], 'method': [328], 'detecting': [330], 'characterising': [332], 'isolates.': [339]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2887568769', 'counts_by_year': [], 'updated_date': '2024-12-12T07:53:53.586395', 'created_date': '2018-08-22'}