Biochromic silole derivatives: a single dye for differentiation, quantitation and imaging of live/dead cells

Name: Work Video:
Duration: 3 min 30 s
Description: A new method using a single cell-permeable biochromic fluorescent dye to differentiate, quantify and image both live and dead cells is reported.
Sijie Chen; Jianzhao Liu; Shouxiang Zhang; Engui Zhao; Chris Y. Y. Yu; Roozbeh Hushiarian; Yuning Hong; Ben Zhong Tang
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China', 'Division of Biomedical Engineering, and Division of Life Science', 'Institute of Molecular Functional Materials', 'MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Zheda Road 38, Hangzhou 310027, China', 'State Key Laboratory of Neuroscience'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute of Molecular Functional Materials, State Key Laboratory of Neuroscience, Division of Biomedical Engineering, and Division of Life Science, The Hong Kong University of Science and Technology, Kowloon, Hong Kong, China', 'institution_ids': ['https://openalex.org/I4210094881', 'https://openalex.org/I889458895', 'https://openalex.org/I200769079']}, {'raw_affiliation_string': 'MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer 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National Engineering Research Center for Tissue Restoration and Reconstruction, Institute of Molecular Functional Materials, State Key Laboratory of Neuroscience, Division of Biomedical Engineering, and Division of Life Science, The Hong Kong University of Science and Technology, Kowloon, Hong Kong, China', 'Division of Biomedical Engineering, and Division of Life Science', 'Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction', 'Institute of Molecular Functional Materials', 'State Key Laboratory of Neuroscience'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute of Molecular Functional Materials, State Key Laboratory of Neuroscience, Division of Biomedical Engineering, and Division of Life Science, The Hong Kong University of Science and Technology, Kowloon, Hong Kong, China', 'institution_ids': 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